"Bile Acids and Salts" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Steroid acids and salts. The primary bile acids are derived from cholesterol in the liver and usually conjugated with glycine or taurine. The secondary bile acids are further modified by bacteria in the intestine. They play an important role in the digestion and absorption of fat. They have also been used pharmacologically, especially in the treatment of gallstones.
| Descriptor ID |
D001647
|
| MeSH Number(s) |
D04.210.500.105
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Bile Acids and Salts".
Below are MeSH descriptors whose meaning is more specific than "Bile Acids and Salts".
This graph shows the total number of publications written about "Bile Acids and Salts" by people in this website by year, and whether "Bile Acids and Salts" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 2 | 2 | 4 |
| 2012 | 0 | 2 | 2 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 2 | 3 |
| 2015 | 2 | 1 | 3 |
| 2016 | 2 | 1 | 3 |
| 2017 | 1 | 1 | 2 |
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 1 | 2 |
| 2020 | 0 | 3 | 3 |
| 2022 | 1 | 1 | 2 |
| 2023 | 0 | 3 | 3 |
| 2024 | 4 | 1 | 5 |
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Below are the most recent publications written about "Bile Acids and Salts" by people in Profiles.
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Crohn's Disease-Associated Pathogenic Mutation in the Manganese Transporter ZIP8 Shifts the Ileal and Rectal Mucosal Microbiota Implicating Aberrant Bile Acid Metabolism. Inflamm Bowel Dis. 2024 Aug 01; 30(8):1379-1388.
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Antibiotic-Induced Gut Microbiota Dysbiosis Modulates Host Transcriptome and m6A Epitranscriptome via Bile Acid Metabolism. Adv Sci (Weinh). 2024 Jul; 11(28):e2307981.
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Structure of antiviral drug bulevirtide bound to hepatitis B and D virus receptor protein NTCP. Nat Commun. 2024 Mar 20; 15(1):2476.
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Tiny heroes: Microbiota-modified bile acid metabolites protect against drug-induced gut damage. Am J Transplant. 2024 Jul; 24(7):1105-1107.
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Microbially catalyzed conjugation of GABA and tyramine to bile acids. J Bacteriol. 2024 01 25; 206(1):e0042623.
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Bile acid fitness determinants of a Bacteroides fragilis isolate from a human pouchitis patient. mBio. 2024 Jan 16; 15(1):e0283023.
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Strain dropouts reveal interactions that govern the metabolic output of the gut microbiome. Cell. 2023 06 22; 186(13):2839-2852.e21.
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Intestinal bile acids provide a surmountable barrier against C. difficile TcdB-induced disease pathogenesis. Proc Natl Acad Sci U S A. 2023 05 09; 120(19):e2301252120.
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Immunomodulatory fecal metabolites are associated with mortality in COVID-19 patients with respiratory failure. Nat Commun. 2022 11 03; 13(1):6615.
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Structure of human NTCP reveals the basis of recognition and sodium-driven transport of bile salts into the liver. Cell Res. 2022 08; 32(8):773-776.