"Peripheral Tolerance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The mechanism, in peripheral lymphoid organs (LYMPH NODES; SPLEEN; TONSILS; and mucosal-associated lymphoid tissue), that prevents mature lymphocytes from reacting to SELF-ANTIGENS. This is accomplished through a variety of means including CLONAL ANERGY and CLONAL DELETION.
| Descriptor ID |
D061166
|
| MeSH Number(s) |
G12.535.425.800.600
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| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Peripheral Tolerance".
Below are MeSH descriptors whose meaning is more specific than "Peripheral Tolerance".
This graph shows the total number of publications written about "Peripheral Tolerance" by people in this website by year, and whether "Peripheral Tolerance" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Peripheral Tolerance" by people in Profiles.
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Cbl-b deficiency prevents functional but not phenotypic T cell anergy. J Exp Med. 2021 07 05; 218(7).
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Engineering antigen-specific immunological tolerance. Curr Opin Immunol. 2015 Aug; 35:80-8.