MAP Kinase Kinase Kinase 1
"MAP Kinase Kinase Kinase 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 195-kDa zinc finger motif-containing MAP kinase kinase kinase with broad specificity for MAP KINASE KINASES. It localizes to the CYTOSKELETON and can activate a variety of MAP kinase-dependent pathways.
|MAP Kinase Kinase Kinase 1
- MAP Kinase Kinase Kinase 1
- MEKK1 Protein
- Mitogen-Activated Protein Kinase Kinase Kinase 1
- Mitogen Activated Protein Kinase Kinase Kinase 1
- MEKK-1 Protein Kinase
- MEKK 1 Protein Kinase
- Protein Kinase, MEKK-1
- MEK Kinase 1
- MEKK1 Protein Kinase
- MAP3K1 Protein
- MAP ERK Kinase Kinase 1
Below are MeSH descriptors whose meaning is more general than "MAP Kinase Kinase Kinase 1".
Below are MeSH descriptors whose meaning is more specific than "MAP Kinase Kinase Kinase 1".
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Below are the most recent publications written about "MAP Kinase Kinase Kinase 1" by people in Profiles.
Selumetinib with and without erlotinib in KRAS mutant and KRAS wild-type advanced nonsmall-cell lung cancer. Ann Oncol. 2016 Apr; 27(4):693-9.
Obatoclax overcomes resistance to cell death in aggressive thyroid carcinomas by countering Bcl2a1 and Mcl1 overexpression. Endocr Relat Cancer. 2014 Oct; 21(5):755-67.
Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers. Am J Hum Genet. 2008 Apr; 82(4):937-48.
Activation of extracellular signal-regulated kinases potentiates hemin toxicity in astrocyte cultures. J Neurochem. 2001 Nov; 79(3):545-55.
Extracellular signal-regulated kinase 1/2-mediated phosphorylation of cytosolic phospholipase A2 is essential for human eosinophil adhesion to fibronectin. J Immunol. 2001 Mar 01; 166(5):3515-21.
Colony-stimulating factor-1 receptor utilizes multiple signaling pathways to induce cyclin D2 expression. Mol Biol Cell. 2000 Nov; 11(11):3835-48.
Role for Lyn tyrosine kinase as a regulator of stress-activated protein kinase activity in response to DNA damage. Mol Cell Biol. 2000 Aug; 20(15):5370-80.
Activation of MEK kinase 1 by the c-Abl protein tyrosine kinase in response to DNA damage. Mol Cell Biol. 2000 Jul; 20(14):4979-89.
Raf, but not MEK or ERK, is sufficient for differentiation of hippocampal neuronal cells. Mol Cell Biol. 1996 Apr; 16(4):1458-70.