 Ventral Tegmental Area
"Ventral Tegmental Area" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A region in the mesencephalon which is dorsomedial to the substantia nigra and ventral to the red nucleus. The mesocortical and mesolimbic dopaminergic systems originate here, including an important projection to the nucleus accumbens. Overactivity of the cells in this area has been suspected to contribute to the positive symptoms of schizophrenia.
| Descriptor ID |
D017557
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| MeSH Number(s) |
A08.186.211.132.659.822.820 A08.186.211.653.822.820
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Ventral Tegmental Area".
Below are MeSH descriptors whose meaning is more specific than "Ventral Tegmental Area".
This graph shows the total number of publications written about "Ventral Tegmental Area" by people in this website by year, and whether "Ventral Tegmental Area" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 | | 1996 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 2000 | 2 | 0 | 2 | | 2002 | 3 | 2 | 5 | | 2003 | 1 | 1 | 2 | | 2004 | 1 | 0 | 1 | | 2006 | 1 | 2 | 3 | | 2007 | 2 | 1 | 3 | | 2009 | 0 | 4 | 4 | | 2010 | 1 | 0 | 1 | | 2011 | 2 | 0 | 2 | | 2012 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 | | 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ventral Tegmental Area" by people in Profiles.
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Wang R, Shen YL, Hausknecht KA, Chang L, Haj-Dahmane S, Vezina P, Shen RY. Prenatal ethanol exposure increases risk of psychostimulant addiction. Behav Brain Res. 2019 01 01; 356:51-61.
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Steidl S, O'Sullivan S, Pilat D, Bubula N, Brown J, Vezina P. Operant responding for optogenetic excitation of LDTg inputs to the VTA requires D1 and D2 dopamine receptor activation in the NAcc. Behav Brain Res. 2017 08 30; 333:161-170.
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Singer BF, Bubula N, Li D, Przybycien-Szymanska MM, Bindokas VP, Vezina P. Drug-Paired Contextual Stimuli Increase Dendritic Spine Dynamics in Select Nucleus Accumbens Neurons. Neuropsychopharmacology. 2016 07; 41(8):2178-87.
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Hausknecht K, Haj-Dahmane S, Shen YL, Vezina P, Dlugos C, Shen RY. Excitatory synaptic function and plasticity is persistently altered in ventral tegmental area dopamine neurons after prenatal ethanol exposure. Neuropsychopharmacology. 2015 Mar; 40(4):893-905.
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Baker LK, Mao D, Chi H, Govind AP, Vallejo YF, Iacoviello M, Herrera S, Cortright JJ, Green WN, McGehee DS, Vezina P. Intermittent nicotine exposure upregulates nAChRs in VTA dopamine neurons and sensitises locomotor responding to the drug. Eur J Neurosci. 2013 Mar; 37(6):1004-11.
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McCutcheon JE, Conrad KL, Carr SB, Ford KA, McGehee DS, Marinelli M. Dopamine neurons in the ventral tegmental area fire faster in adolescent rats than in adults. J Neurophysiol. 2012 Sep; 108(6):1620-30.
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Leinninger GM, Opland DM, Jo YH, Faouzi M, Christensen L, Cappellucci LA, Rhodes CJ, Gnegy ME, Becker JB, Pothos EN, Seasholtz AF, Thompson RC, Myers MG. Leptin action via neurotensin neurons controls orexin, the mesolimbic dopamine system and energy balance. Cell Metab. 2011 Sep 07; 14(3):313-23.
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Mao D, Gallagher K, McGehee DS. Nicotine potentiation of excitatory inputs to ventral tegmental area dopamine neurons. J Neurosci. 2011 May 04; 31(18):6710-20.
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Leshan RL, Opland DM, Louis GW, Leinninger GM, Patterson CM, Rhodes CJ, Münzberg H, Myers MG. Ventral tegmental area leptin receptor neurons specifically project to and regulate cocaine- and amphetamine-regulated transcript neurons of the extended central amygdala. J Neurosci. 2010 Apr 21; 30(16):5713-23.
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Mao D, McGehee DS. Nicotine and behavioral sensitization. J Mol Neurosci. 2010 Jan; 40(1-2):154-63.
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