 Mice, Inbred mdx
"Mice, Inbred mdx" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A strain of mice arising from a spontaneous MUTATION (mdx) in inbred C57BL mice. This mutation is X chromosome-linked and produces viable homozygous animals that lack the muscle protein DYSTROPHIN, have high serum levels of muscle ENZYMES, and possess histological lesions similar to human MUSCULAR DYSTROPHY. The histological features, linkage, and map position of mdx make these mice a worthy animal model of DUCHENNE MUSCULAR DYSTROPHY.
| Descriptor ID |
D018101
|
| MeSH Number(s) |
B01.050.050.157.520.420.500 B01.050.050.199.520.520.420.500 B01.050.150.900.649.865.635.505.500.400.420.500 B01.050.150.900.649.865.635.505.500.550.265
|
| Concept/Terms |
Mice, Inbred mdx- Mice, Inbred mdx
- Inbred mdx Mice
- mdx Mice, Inbred
- Mouse, Inbred mdx
- Inbred mdx Mouse
- mdx Mouse, Inbred
- Mice, mdx
- mdx Mice
- Mouse, mdx
- mdx Mouse
|
Below are MeSH descriptors whose meaning is more general than "Mice, Inbred mdx".
- Organisms [B]
- Eukaryota [B01]
- Animals [B01.050]
- Animal Population Groups [B01.050.050]
- Animals, Inbred Strains [B01.050.050.157]
- Mice, Inbred Strains [B01.050.050.157.520]
- Mice, Inbred C57BL [B01.050.050.157.520.420]
- Mice, Inbred mdx [B01.050.050.157.520.420.500]
- Animals, Laboratory [B01.050.050.199]
- Animals, Inbred Strains [B01.050.050.199.520]
- Mice, Inbred Strains [B01.050.050.199.520.520]
- Mice, Inbred C57BL [B01.050.050.199.520.520.420]
- Mice, Inbred mdx [B01.050.050.199.520.520.420.500]
- Chordata [B01.050.150]
- Vertebrates [B01.050.150.900]
- Mammals [B01.050.150.900.649]
- Rodentia [B01.050.150.900.649.865]
- Muridae [B01.050.150.900.649.865.635]
- Murinae [B01.050.150.900.649.865.635.505]
- Mice [B01.050.150.900.649.865.635.505.500]
- Mice, Inbred Strains [B01.050.150.900.649.865.635.505.500.400]
- Mice, Inbred C57BL [B01.050.150.900.649.865.635.505.500.400.420]
- Mice, Inbred mdx [B01.050.150.900.649.865.635.505.500.400.420.500]
- Mice, Mutant Strains [B01.050.150.900.649.865.635.505.500.550]
- Mice, Inbred mdx [B01.050.150.900.649.865.635.505.500.550.265]
Below are MeSH descriptors whose meaning is more specific than "Mice, Inbred mdx".
This graph shows the total number of publications written about "Mice, Inbred mdx" by people in this website by year, and whether "Mice, Inbred mdx" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 0 | 6 | 6 | | 2011 | 0 | 2 | 2 | | 2012 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Mice, Inbred mdx" by people in Profiles.
-
Quattrocelli M, Zelikovich AS, Jiang Z, Peek CB, Demonbreun AR, Kuntz NL, Barish GD, Haldar SM, Bass J, McNally EM. Pulsed glucocorticoids enhance dystrophic muscle performance through epigenetic-metabolic reprogramming. JCI Insight. 2019 12 19; 4(24).
-
Gordish-Dressman H, Willmann R, Dalle Pazze L, Kreibich A, van Putten M, Heydemann A, Bogdanik L, Lutz C, Davies K, Demonbreun AR, Duan D, Elsey D, Fukada SI, Girgenrath M, Patrick Gonzalez J, Grounds MD, Nichols A, Partridge T, Passini M, Sanarica F, Schnell FJ, Wells DJ, Yokota T, Young CS, Zhong Z, Spurney C, Spencer M, De Luca A, Nagaraju K, Aartsma-Rus A. "Of Mice and Measures": A Project to Improve How We Advance Duchenne Muscular Dystrophy Therapies to the Clinic. J Neuromuscul Dis. 2018; 5(4):407-417.
-
Quattrocelli M, Barefield DY, Warner JL, Vo AH, Hadhazy M, Earley JU, Demonbreun AR, McNally EM. Intermittent glucocorticoid steroid dosing enhances muscle repair without eliciting muscle atrophy. J Clin Invest. 2017 Jun 01; 127(6):2418-2432.
-
Smith LR, Hammers DW, Sweeney HL, Barton ER. Increased collagen cross-linking is a signature of dystrophin-deficient muscle. Muscle Nerve. 2016 06; 54(1):71-8.
-
Gutpell KM, Hrinivich WT, Hoffman LM. Skeletal muscle fibrosis in the mdx/utrn+/- mouse validates its suitability as a murine model of Duchenne muscular dystrophy. PLoS One. 2015; 10(1):e0117306.
-
Ceco E, Bogdanovich S, Gardner B, Miller T, DeJesus A, Earley JU, Hadhazy M, Smith LR, Barton ER, Molkentin JD, McNally EM. Targeting latent TGFß release in muscular dystrophy. Sci Transl Med. 2014 Oct 22; 6(259):259ra144.
-
Sharma P, Basu S, Mitchell RW, Stelmack GL, Anderson JE, Halayko AJ. Role of dystrophin in airway smooth muscle phenotype, contraction and lung function. PLoS One. 2014; 9(7):e102737.
-
Wissing ER, Boyer JG, Kwong JQ, Sargent MA, Karch J, McNally EM, Otsu K, Molkentin JD. P38a MAPK underlies muscular dystrophy and myofiber death through a Bax-dependent mechanism. Hum Mol Genet. 2014 Oct 15; 23(20):5452-63.
-
Selsby JT, Acosta P, Sleeper MM, Barton ER, Sweeney HL. Long-term wheel running compromises diaphragm function but improves cardiac and plantarflexor function in the mdx mouse. J Appl Physiol (1985). 2013 Sep 01; 115(5):660-6.
-
Selsby JT, Morine KJ, Pendrak K, Barton ER, Sweeney HL. Rescue of dystrophic skeletal muscle by PGC-1a involves a fast to slow fiber type shift in the mdx mouse. PLoS One. 2012; 7(1):e30063.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|