 Gene Silencing
"Gene Silencing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Interruption or suppression of the expression of a gene at transcriptional or translational levels.
| Descriptor ID |
D020868
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| MeSH Number(s) |
G05.355.315.203.374
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| Concept/Terms |
Gene Silencing- Gene Silencing
- Silencing, Gene
- Gene Inactivation
- Inactivation, Gene
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Below are MeSH descriptors whose meaning is more general than "Gene Silencing".
Below are MeSH descriptors whose meaning is more specific than "Gene Silencing".
This graph shows the total number of publications written about "Gene Silencing" by people in this website by year, and whether "Gene Silencing" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 2 | 2 | | 2001 | 0 | 1 | 1 | | 2002 | 3 | 1 | 4 | | 2003 | 0 | 3 | 3 | | 2004 | 1 | 7 | 8 | | 2005 | 3 | 6 | 9 | | 2006 | 3 | 5 | 8 | | 2007 | 3 | 3 | 6 | | 2008 | 2 | 3 | 5 | | 2009 | 2 | 11 | 13 | | 2010 | 5 | 6 | 11 | | 2011 | 2 | 10 | 12 | | 2012 | 2 | 7 | 9 | | 2013 | 1 | 8 | 9 | | 2014 | 1 | 8 | 9 | | 2015 | 0 | 6 | 6 | | 2016 | 2 | 6 | 8 | | 2017 | 0 | 5 | 5 | | 2018 | 3 | 1 | 4 | | 2019 | 1 | 1 | 2 | | 2020 | 1 | 1 | 2 | | 2021 | 0 | 2 | 2 |
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Below are the most recent publications written about "Gene Silencing" by people in Profiles.
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Li W, Tran V, Shaked I, Xue B, Moore T, Lightle R, Kleinfeld D, Awad IA, Ginsberg MH. Abortive intussusceptive angiogenesis causes multi-cavernous vascular malformations. Elife. 2021 05 20; 10.
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Lapadat R, Anani WQ, Bensing KM, Aeschlimann J, Vege S, Lomas-Francis C, Westhoff CM, Fadeyi EA, Denomme GA. A pair of S-silencing single nucleotide variants cis-linked on GYPB. Transfusion. 2021 04; 61(4):E34-E36.
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Karunakaran D, Nguyen MA, Geoffrion M, Vreeken D, Lister Z, Cheng HS, Otte N, Essebier P, Wyatt H, Kandiah JW, Jung R, Alenghat FJ, Mompeon A, Lee R, Pan C, Gordon E, Rasheed A, Lusis AJ, Liu P, Matic LP, Hedin U, Fish JE, Guo L, Kolodgie F, Virmani R, van Gils JM, Rayner KJ. RIPK1 Expression Associates With Inflammation in Early Atherosclerosis in Humans and Can Be Therapeutically Silenced to Reduce NF-?B Activation and Atherogenesis in Mice. Circulation. 2021 01 12; 143(2):163-177.
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Cheng Q, Lin J, Chen Q, Zheng L, Tang Y, Wang F, Huang X, Zhang Y, Li S, Yang Z, Zhou P, He TC, Luo W, Zhang H. Role of Special AT-Rich Sequence-Binding Protein 2 in the Osteogenesis of Human Dental Mesenchymal Stem Cells. Stem Cells Dev. 2020 08; 29(16):1059-1072.
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Wang H, Cao Y, Shu L, Zhu Y, Peng Q, Ran L, Wu J, Luo Y, Zuo G, Luo J, Zhou L, Shi Q, Weng Y, Huang A, He TC, Fan J. Long non-coding RNA (lncRNA) H19 induces hepatic steatosis through activating MLXIPL and mTORC1 networks in hepatocytes. J Cell Mol Med. 2020 01; 24(2):1399-1412.
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Wu WS, Brown JS, Chen TT, Chu YH, Huang WC, Tu S, Lee HC. piRTarBase: a database of piRNA targeting sites and their roles in gene regulation. Nucleic Acids Res. 2019 01 08; 47(D1):D181-D187.
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Maldonado L, Brait M, Izumchenko E, Begum S, Chatterjee A, Sen T, Loyo M, Barbosa A, Poeta ML, Makarev E, Zhavoronkov A, Fazio VM, Angioli R, Rabitti C, Ongenaert M, Van Criekinge W, Noordhuis MG, de Graeff P, Wisman GBA, van der Zee AGJ, Hoque MO. Integrated transcriptomic and epigenomic analysis of ovarian cancer reveals epigenetically silenced GULP1. Cancer Lett. 2018 10 01; 433:242-251.
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Boboila S, Lopez G, Yu J, Banerjee D, Kadenhe-Chiweshe A, Connolly EP, Kandel JJ, Rajbhandari P, Silva JM, Califano A, Yamashiro DJ. Transcription factor activating protein 4 is synthetically lethal and a master regulator of MYCN-amplified neuroblastoma. Oncogene. 2018 10; 37(40):5451-5465.
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Ward MC, Zhao S, Luo K, Pavlovic BJ, Karimi MM, Stephens M, Gilad Y. Silencing of transposable elements may not be a major driver of regulatory evolution in primate iPSCs. Elife. 2018 04 12; 7.
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Zhang D, Tu S, Stubna M, Wu WS, Huang WC, Weng Z, Lee HC. The piRNA targeting rules and the resistance to piRNA silencing in endogenous genes. Science. 2018 02 02; 359(6375):587-592.
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