 Gene Silencing
"Gene Silencing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Interruption or suppression of the expression of a gene at transcriptional or translational levels.
| Descriptor ID |
D020868
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| MeSH Number(s) |
G05.355.315.203.374
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| Concept/Terms |
Gene Silencing- Gene Silencing
- Silencing, Gene
- Gene Inactivation
- Inactivation, Gene
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Below are MeSH descriptors whose meaning is more general than "Gene Silencing".
Below are MeSH descriptors whose meaning is more specific than "Gene Silencing".
This graph shows the total number of publications written about "Gene Silencing" by people in this website by year, and whether "Gene Silencing" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 2 | 2 | | 2001 | 0 | 1 | 1 | | 2002 | 3 | 1 | 4 | | 2003 | 0 | 3 | 3 | | 2004 | 1 | 7 | 8 | | 2005 | 3 | 6 | 9 | | 2006 | 3 | 5 | 8 | | 2007 | 3 | 3 | 6 | | 2008 | 2 | 3 | 5 | | 2009 | 2 | 11 | 13 | | 2010 | 5 | 6 | 11 | | 2011 | 2 | 10 | 12 | | 2012 | 2 | 7 | 9 | | 2013 | 1 | 8 | 9 | | 2014 | 1 | 8 | 9 | | 2015 | 0 | 6 | 6 | | 2016 | 2 | 6 | 8 | | 2017 | 0 | 4 | 4 | | 2018 | 3 | 1 | 4 | | 2019 | 1 | 1 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Gene Silencing" by people in Profiles.
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Wang H, Cao Y, Shu L, Zhu Y, Peng Q, Ran L, Wu J, Luo Y, Zuo G, Luo J, Zhou L, Shi Q, Weng Y, Huang A, He TC, Fan J. Long non-coding RNA (lncRNA) H19 induces hepatic steatosis through activating MLXIPL and mTORC1 networks in hepatocytes. J Cell Mol Med. 2020 01; 24(2):1399-1412.
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Wu WS, Brown JS, Chen TT, Chu YH, Huang WC, Tu S, Lee HC. piRTarBase: a database of piRNA targeting sites and their roles in gene regulation. Nucleic Acids Res. 2019 01 08; 47(D1):D181-D187.
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Maldonado L, Brait M, Izumchenko E, Begum S, Chatterjee A, Sen T, Loyo M, Barbosa A, Poeta ML, Makarev E, Zhavoronkov A, Fazio VM, Angioli R, Rabitti C, Ongenaert M, Van Criekinge W, Noordhuis MG, de Graeff P, Wisman GBA, van der Zee AGJ, Hoque MO. Integrated transcriptomic and epigenomic analysis of ovarian cancer reveals epigenetically silenced GULP1. Cancer Lett. 2018 10 01; 433:242-251.
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Boboila S, Lopez G, Yu J, Banerjee D, Kadenhe-Chiweshe A, Connolly EP, Kandel JJ, Rajbhandari P, Silva JM, Califano A, Yamashiro DJ. Transcription factor activating protein 4 is synthetically lethal and a master regulator of MYCN-amplified neuroblastoma. Oncogene. 2018 10; 37(40):5451-5465.
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Ward MC, Zhao S, Luo K, Pavlovic BJ, Karimi MM, Stephens M, Gilad Y. Silencing of transposable elements may not be a major driver of regulatory evolution in primate iPSCs. Elife. 2018 04 12; 7.
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Zhang D, Tu S, Stubna M, Wu WS, Huang WC, Weng Z, Lee HC. The piRNA targeting rules and the resistance to piRNA silencing in endogenous genes. Science. 2018 02 02; 359(6375):587-592.
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Wang L, Joshi P, Miller EL, Higgins L, Slattery M, Simon JA. A Role for Monomethylation of Histone H3-K27 in Gene Activity in Drosophila. Genetics. 2018 03; 208(3):1023-1036.
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Yang XH, Tang F, Shin J, Cunningham JM. Incorporating genomic, transcriptomic and clinical data: a prognostic and stem cell-like MYC and PRC imbalance in high-risk neuroblastoma. BMC Syst Biol. 2017 Oct 03; 11(Suppl 5):92.
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Crisp PA, Ganguly DR, Smith AB, Murray KD, Estavillo GM, Searle I, Ford E, Bogdanovic O, Lister R, Borevitz JO, Eichten SR, Pogson BJ. Rapid Recovery Gene Downregulation during Excess-Light Stress and Recovery in Arabidopsis. Plant Cell. 2017 Aug; 29(8):1836-1863.
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Al-Hendy A, Laknaur A, Diamond MP, Ismail N, Boyer TG, Halder SK. Silencing Med12 Gene Reduces Proliferation of Human Leiomyoma Cells Mediated via Wnt/ß-Catenin Signaling Pathway. Endocrinology. 2017 03 01; 158(3):592-603.
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