 Immunoglobulins, Thyroid-Stimulating
"Immunoglobulins, Thyroid-Stimulating" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Autoantibodies that bind to the thyroid-stimulating hormone (TSH) receptor (RECEPTORS, THYROTROPIN) on thyroid epithelial cells. The autoantibodies mimic TSH causing an unregulated production of thyroid hormones characteristic of GRAVES DISEASE.
| Descriptor ID |
D018828
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| MeSH Number(s) |
D12.776.124.486.485.114.323.480 D12.776.124.486.485.114.648 D12.776.124.790.651.114.323.480 D12.776.124.790.651.114.648 D12.776.377.715.548.114.323.480 D12.776.377.715.548.114.648
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| Concept/Terms |
Immunoglobulins, Thyroid-Stimulating- Immunoglobulins, Thyroid-Stimulating
- Thyroid-Stimulating Antibodies
- Thyroid Stimulating Antibodies
- Thyroid-Stimulating Immunoglobulin
- Thyroid Stimulating Immunoglobulin
- Immunoglobulin, Thyroid-Stimulating
- Immunoglobulin, Thyroid Stimulating
- Antibodies, Thyroid-Stimulating
- Thyroid Stimulating Antibody
- Antibody, Thyroid Stimulating
- Stimulating Antibody, Thyroid
- Thyroid-Stimulating Immunoglobulins
- Thyroid Stimulating Immunoglobulins
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Below are MeSH descriptors whose meaning is more general than "Immunoglobulins, Thyroid-Stimulating".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulins, Thyroid-Stimulating".
This graph shows the total number of publications written about "Immunoglobulins, Thyroid-Stimulating" by people in this website by year, and whether "Immunoglobulins, Thyroid-Stimulating" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 | | 2000 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 |
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Below are the most recent publications written about "Immunoglobulins, Thyroid-Stimulating" by people in Profiles.
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Majima T, Komatsu Y, Doi K, Takagi C, Shigemoto M, Fukao A, Morimoto T, Corners J, Nakao K. Negative correlation between bone mineral density and TSH receptor antibodies in male patients with untreated Graves' disease. Osteoporos Int. 2006; 17(7):1103-10.
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Costagliola S, Bonomi M, Morgenthaler NG, Van Durme J, Panneels V, Refetoff S, Vassart G. Delineation of the discontinuous-conformational epitope of a monoclonal antibody displaying full in vitro and in vivo thyrotropin activity. Mol Endocrinol. 2004 Dec; 18(12):3020-34.
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Costagliola S, Many MC, Denef JF, Pohlenz J, Refetoff S, Vassart G. Genetic immunization of outbred mice with thyrotropin receptor cDNA provides a model of Graves' disease. J Clin Invest. 2000 Mar; 105(6):803-11.
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Hidaka Y, Guimaraes V, Soliman M, Yanagawa T, Okamoto Y, Quintans J, DeGroot LJ. Production of thyroid-stimulating antibodies in mice by immunization with T-cell epitopes of human thyrotropin receptor. Endocrinology. 1995 Apr; 136(4):1642-7.
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Soliman M, Kaplan E, Yanagawa T, Hidaka Y, Fisfalen ME, DeGroot LJ. T-cells recognize multiple epitopes in the human thyrotropin receptor extracellular domain. J Clin Endocrinol Metab. 1995 Mar; 80(3):905-14.
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