Macrophage Inflammatory Proteins
"Macrophage Inflammatory Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Heparin-binding proteins that exhibit a number of inflammatory and immunoregulatory activities. Originally identified as secretory products of MACROPHAGES, these chemokines are produced by a variety of cell types including NEUTROPHILS; FIBROBLASTS; and EPITHELIAL CELLS. They likely play a significant role in respiratory tract defenses.
| Descriptor ID |
D019402
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| MeSH Number(s) |
D12.644.276.374.200.600 D12.776.467.374.200.600 D23.125.300.600 D23.469.200.600 D23.529.374.200.600
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Macrophage Inflammatory Proteins".
Below are MeSH descriptors whose meaning is more specific than "Macrophage Inflammatory Proteins".
This graph shows the total number of publications written about "Macrophage Inflammatory Proteins" by people in this website by year, and whether "Macrophage Inflammatory Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 1 | 0 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Macrophage Inflammatory Proteins" by people in Profiles.
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Polymerization of MIP-1 chemokine (CCL3 and CCL4) and clearance of MIP-1 by insulin-degrading enzyme. EMBO J. 2010 Dec 01; 29(23):3952-66.
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Successful immunotherapy with IL-2/anti-CD40 induces the chemokine-mediated mitigation of an immunosuppressive tumor microenvironment. Proc Natl Acad Sci U S A. 2009 Nov 17; 106(46):19455-60.
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Complementation of human papillomavirus type 16 E6 and E7 by Jagged1-specific Notch1-phosphatidylinositol 3-kinase signaling involves pleiotropic oncogenic functions independent of CBF1;Su(H);Lag-1 activation. J Virol. 2005 Jun; 79(12):7889-98.
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Pancreatic cancer escape variants that evade immunogene therapy through loss of sensitivity to IFNgamma-induced apoptosis. Gene Ther. 2003 Jul; 10(13):1067-78.
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ESE-1, an enterocyte-specific Ets transcription factor, regulates MIP-3alpha gene expression in Caco-2 human colonic epithelial cells. J Biol Chem. 2003 Jan 10; 278(2):875-84.
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Genetic deficiency in the chemokine receptor CCR1 protects against acute Clostridium difficile toxin A enteritis in mice. Gastroenterology. 2002 Mar; 122(3):725-33.
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Central nervous system chemokine expression during Theiler's virus-induced demyelinating disease. J Neurovirol. 1999 Dec; 5(6):635-42.
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Reduction of the viral load of HIV-1 after the intraperitoneal administration of dextrin 2-sulphate in patients with AIDS. AIDS. 1998 Mar 05; 12(4):399-409.
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Cloning and characterization of exodus, a novel beta-chemokine. Blood. 1997 May 01; 89(9):3315-22.
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lin-12 and glp-1 are required zygotically for early embryonic cellular interactions and are regulated by maternal GLP-1 signaling in Caenorhabditis elegans. Development. 1996 Dec; 122(12):4105-17.