 Serine C-Palmitoyltransferase
"Serine C-Palmitoyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A key enzyme in SPHINGOLIPIDS biosynthesis, this enzyme catalyzes the pyridoxal-5'-phosphate-dependent condensation of L-SERINE and PALMITOYL COENZYME A to 3-dehydro-D-sphinganine. The enzyme consists of two different subunits.
| Descriptor ID |
D051102
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| MeSH Number(s) |
D08.811.913.050.668
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| Concept/Terms |
Serine C-Palmitoyltransferase- Serine C-Palmitoyltransferase
- C-Palmitoyltransferase, Serine
- Serine C Palmitoyltransferase
- Serine Palmitoyltransferase
- Palmitoyltransferase, Serine
- Palmitoyl-CoA-L-Serine C-Palmitoyltransferase (Decarboxylating)
- Palmitoyl-Coenzyme A-L-Serine C-Palmitoyltransferase (Decarboxylating)
Long Chain Base Biosynthesis Protein 2- Long Chain Base Biosynthesis Protein 2
- Serine-Palmitoyl-CoA Transferase 2
- Serine Palmitoyl CoA Transferase 2
- Transferase 2, Serine-Palmitoyl-CoA
- Serine Palmitoyltransferase 2
- Palmitoyltransferase 2, Serine
- Serine Palmitoyltransferase, Long Chain Base Subunit 2
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Below are MeSH descriptors whose meaning is more general than "Serine C-Palmitoyltransferase".
Below are MeSH descriptors whose meaning is more specific than "Serine C-Palmitoyltransferase".
This graph shows the total number of publications written about "Serine C-Palmitoyltransferase" by people in this website by year, and whether "Serine C-Palmitoyltransferase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 | | 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Serine C-Palmitoyltransferase" by people in Profiles.
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Shahin MH, Gong Y, Frye RF, Rotroff DM, Beitelshees AL, Baillie RA, Chapman AB, Gums JG, Turner ST, Boerwinkle E, Motsinger-Reif A, Fiehn O, Cooper-DeHoff RM, Han X, Kaddurah-Daouk R, Johnson JA. Sphingolipid Metabolic Pathway Impacts Thiazide Diuretics Blood Pressure Response: Insights From Genomics, Metabolomics, and Lipidomics. J Am Heart Assoc. 2017 12 29; 7(1).
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Gorshkova I, Zhou T, Mathew B, Jacobson JR, Takekoshi D, Bhattacharya P, Smith B, Aydogan B, Weichselbaum RR, Natarajan V, Garcia JG, Berdyshev EV. Inhibition of serine palmitoyltransferase delays the onset of radiation-induced pulmonary fibrosis through the negative regulation of sphingosine kinase-1 expression. J Lipid Res. 2012 Aug; 53(8):1553-68.
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