 Leukemia Inhibitory Factor
"Leukemia Inhibitory Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An INTERLEUKIN-6 related cytokine that exhibits pleiotrophic effects on many physiological systems that involve cell proliferation, differentiation, and survival. Leukemia inhibitory factor binds to and acts through the lif receptor.
| Descriptor ID |
D053605
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| MeSH Number(s) |
D12.644.276.374.470 D12.776.467.374.470 D23.529.374.470
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| Concept/Terms |
Leukemia Inhibitory Factor- Leukemia Inhibitory Factor
- Inhibitory Factor, Leukemia
- Myeloid Differentiation-Stimulating Factor
- Differentiation-Stimulating Factor, Myeloid
- Myeloid Differentiation Stimulating Factor
- Differentiation-Stimulating Factor
- Differentiation Stimulating Factor
- Cholinergic Differentiation Factor
- Differentiation Factor, Cholinergic
- D Factor (Leukemia Inhibitory Factor)
Emfilermin- Emfilermin
- AMRAD Brand of Recombinant Human Leukemia Inhibitory Factor
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Below are MeSH descriptors whose meaning is more general than "Leukemia Inhibitory Factor".
Below are MeSH descriptors whose meaning is more specific than "Leukemia Inhibitory Factor".
This graph shows the total number of publications written about "Leukemia Inhibitory Factor" by people in this website by year, and whether "Leukemia Inhibitory Factor" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Leukemia Inhibitory Factor" by people in Profiles.
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Lee ST, Yun JI, van der Vlies AJ, Kontos S, Jang M, Gong SP, Kim DY, Lim JM, Hubbell JA. Long-term maintenance of mouse embryonic stem cell pluripotency by manipulating integrin signaling within 3D scaffolds without active Stat3. Biomaterials. 2012 Dec; 33(35):8934-42.
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Gharib SA, Dayyat EA, Khalyfa A, Kim J, Clair HB, Kucia M, Gozal D. Intermittent hypoxia mobilizes bone marrow-derived very small embryonic-like stem cells and activates developmental transcriptional programs in mice. Sleep. 2010 Nov; 33(11):1439-46.
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Davis ID, Kiers L, MacGregor L, Quinn M, Arezzo J, Green M, Rosenthal M, Chia M, Michael M, Bartley P, Harrison L, Daly M. A randomized, double-blinded, placebo-controlled phase II trial of recombinant human leukemia inhibitory factor (rhuLIF, emfilermin, AM424) to prevent chemotherapy-induced peripheral neuropathy. Clin Cancer Res. 2005 Mar 01; 11(5):1890-8.
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Chung TD, Yu JJ, Spiotto MT, Bartkowski M, Simons JW. Characterization of the role of IL-6 in the progression of prostate cancer. Prostate. 1999 Feb 15; 38(3):199-207.
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Sarraf P, Frederich RC, Turner EM, Ma G, Jaskowiak NT, Rivet DJ, Flier JS, Lowell BB, Fraker DL, Alexander HR. Multiple cytokines and acute inflammation raise mouse leptin levels: potential role in inflammatory anorexia. J Exp Med. 1997 Jan 06; 185(1):171-5.
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