Isovaleryl-CoA Dehydrogenase
"Isovaleryl-CoA Dehydrogenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mitochondrial flavoprotein, this enzyme catalyzes the oxidation of 3-methylbutanoyl-CoA to 3-methylbut-2-enoyl-CoA using FAD as a cofactor. Defects in the enzyme, is associated with isovaleric acidemia (IVA).
| Descriptor ID |
D050769
|
| MeSH Number(s) |
D08.811.682.660.462
|
| Concept/Terms |
Isovaleryl-CoA Dehydrogenase- Isovaleryl-CoA Dehydrogenase
- Dehydrogenase, Isovaleryl-CoA
- Isovaleryl CoA Dehydrogenase
- CoA Dehydrogenase, Isovaleryl
- Dehydrogenase, Isovaleryl CoA
- Isovaleryl-Coenzyme A Dehydrogenase
- Dehydrogenase, Isovaleryl-Coenzyme A
- Isovaleryl Coenzyme A Dehydrogenase
|
Below are MeSH descriptors whose meaning is more general than "Isovaleryl-CoA Dehydrogenase".
Below are MeSH descriptors whose meaning is more specific than "Isovaleryl-CoA Dehydrogenase".
This graph shows the total number of publications written about "Isovaleryl-CoA Dehydrogenase" by people in this website by year, and whether "Isovaleryl-CoA Dehydrogenase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
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Below are the most recent publications written about "Isovaleryl-CoA Dehydrogenase" by people in Profiles.
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Arginine 387 of human isovaleryl-CoA dehydrogenase plays a crucial role in substrate/product binding. Mol Genet Metab. 2001 Sep-Oct; 74(1-2):226-37.
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Mitochondrial import and processing of wild type and type III mutant isovaleryl-CoA dehydrogenase. J Biol Chem. 2000 Mar 17; 275(11):7958-63.
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Characterization of molecular defects in isovaleryl-CoA dehydrogenase in patients with isovaleric acidemia. Biochemistry. 1998 Jul 14; 37(28):10325-35.