STAT4 Transcription Factor
"STAT4 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-12 in T-LYMPHOCYTES. Stat4 is an important signaling molecule for differentiation in TH1 CELLS.
| Descriptor ID |
D050797
|
| MeSH Number(s) |
D12.644.360.024.342.400 D12.776.157.057.186.400 D12.776.476.024.430.400 D12.776.930.840.400
|
| Concept/Terms |
STAT4 Transcription Factor- STAT4 Transcription Factor
- Transcription Factor, STAT4
- Signal Transducer and Activator of Transcription 4
- STAT4 Protein
- Transcription Factor STAT4
|
Below are MeSH descriptors whose meaning is more general than "STAT4 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "STAT4 Transcription Factor".
This graph shows the total number of publications written about "STAT4 Transcription Factor" by people in this website by year, and whether "STAT4 Transcription Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "STAT4 Transcription Factor" by people in Profiles.
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Variants in STAT4 Associated With Cure of Chronic HBV Infection in HBeAg-positive Patients Treated With Pegylated Interferon-alpha. Clin Gastroenterol Hepatol. 2020 01; 18(1):196-204.e8.
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Signaling by the phosphatase MKP-1 in dendritic cells imprints distinct effector and regulatory T cell fates. Immunity. 2011 Jul 22; 35(1):45-58.
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High-density genotyping of STAT4 reveals multiple haplotypic associations with systemic lupus erythematosus in different racial groups. Arthritis Rheum. 2009 Apr; 60(4):1085-95.
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Association of STAT4 with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in the Japanese population. Arthritis Rheum. 2008 Jul; 58(7):1940-6.
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Mechanistic insights into impaired dendritic cell function by rapamycin: inhibition of Jak2/Stat4 signaling pathway. J Immunol. 2004 Feb 01; 172(3):1355-63.
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Inhibition of IL-12 signaling Stat4/IFN-gamma pathway by rapamycin is associated with impaired dendritic [correction of dendritc] cell function. Transplant Proc. 2002 Aug; 34(5):1394-5.
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Role of STAT6 signaling in the induction and long-term maintenance of tolerance mediated by CTLA4-Ig. Transplant Proc. 2001 Feb-Mar; 33(1-2):214-6.
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Role of STAT4 and STAT6 signaling in allograft rejection and CTLA4-Ig-mediated tolerance. J Immunol. 2000 Nov 15; 165(10):5580-7.