"Receptor, Notch1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A notch receptor that interacts with a variety of ligands and regulates SIGNAL TRANSDUCTION PATHWAYS for multiple cellular processes. It is widely expressed during EMBRYOGENESIS and is essential for EMBRYONIC DEVELOPMENT.
| Descriptor ID |
D051881
|
| MeSH Number(s) |
D12.776.543.750.725.500 D12.776.930.770.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Notch1".
Below are MeSH descriptors whose meaning is more specific than "Receptor, Notch1".
This graph shows the total number of publications written about "Receptor, Notch1" by people in this website by year, and whether "Receptor, Notch1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 3 | 3 |
| 2006 | 3 | 1 | 4 |
| 2007 | 1 | 0 | 1 |
| 2008 | 3 | 2 | 5 |
| 2009 | 3 | 0 | 3 |
| 2010 | 5 | 1 | 6 |
| 2011 | 4 | 2 | 6 |
| 2012 | 1 | 3 | 4 |
| 2013 | 2 | 0 | 2 |
| 2014 | 1 | 2 | 3 |
| 2015 | 3 | 1 | 4 |
| 2016 | 1 | 0 | 1 |
| 2017 | 3 | 0 | 3 |
| 2018 | 3 | 2 | 5 |
| 2019 | 1 | 1 | 2 |
| 2020 | 1 | 4 | 5 |
| 2021 | 3 | 0 | 3 |
| 2022 | 1 | 0 | 1 |
| 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Receptor, Notch1" by people in Profiles.
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Chronic Lymphocytic Leukemia With Two B-Cell Populations of Discordant Light Chain Restrictions in Individual Patients: Parallel Development of Biclonal B-Cell Neoplasms or Clonal Evolution With Isotype Switch? Am J Clin Pathol. 2023 04 04; 159(4):337-351.
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Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth. Nat Genet. 2023 02; 55(2):232-245.
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Non-coding NOTCH1 mutations in chronic lymphocytic leukemia negatively impact prognosis. Am J Hematol. 2022 03 01; 97(3):E100-E102.
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Simulations reveal that different responses to cell crowding determine the expansion of p53 and Notch mutant clones in squamous epithelia. J R Soc Interface. 2021 10; 18(183):20210607.
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Perinatal angiogenesis from pre-existing coronary vessels via DLL4-NOTCH1 signalling. Nat Cell Biol. 2021 09; 23(9):967-977.
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The Spatiotemporal Expression of Notch1 and Numb and Their Functional Interaction during Cardiac Morphogenesis. Cells. 2021 08 25; 10(9).
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Selection of Oncogenic Mutant Clones in Normal Human Skin Varies with Body Site. Cancer Discov. 2021 02; 11(2):340-361.
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Combinatorial ETS1-dependent control of oncogenic NOTCH1 enhancers in T-cell leukemia. Blood Cancer Discov. 2020 09; 1(2):178-197.
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Control of sinus venous valve and sinoatrial node development by endocardial NOTCH1. Cardiovasc Res. 2020 07 01; 116(8):1473-1486.
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Spatial competition shapes the dynamic mutational landscape of normal esophageal epithelium. Nat Genet. 2020 06; 52(6):604-614.