"Receptor, Notch3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A notch receptor characterized by a large extracellular domain containing 34 EPIDERMAL GROWTH FACTOR-like repeats. It functions to regulate CELL DIFFERENTIATION; APOPTOSIS; and CELL PROLIFERATION. Mutations in the EGF repeats of Notch-3 are associated with CADASIL.
| Descriptor ID |
D000071656
|
| MeSH Number(s) |
D12.776.543.750.725.875 D12.776.930.770.875
|
| Concept/Terms |
Receptor, Notch3- Receptor, Notch3
- Notch-3 Protein
- Notch 3 Protein
- Notch3 Protein
- Notch-3 Receptor
- Notch 3 Receptor
- Notch3 Receptor
- Neurogenic Locus Notch Homolog Protein 3
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Notch3".
Below are MeSH descriptors whose meaning is more specific than "Receptor, Notch3".
This graph shows the total number of publications written about "Receptor, Notch3" by people in this website by year, and whether "Receptor, Notch3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptor, Notch3" by people in Profiles.
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Comparative genomic analysis of esophageal adenocarcinoma and squamous cell carcinoma. Cancer Discov. 2012 Oct; 2(10):899-905.
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Smooth muscle Notch1 mediates neointimal formation after vascular injury. Circulation. 2009 May 26; 119(20):2686-92.
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Linking Notch signaling to ischemic stroke. Proc Natl Acad Sci U S A. 2008 Mar 25; 105(12):4856-61.
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Modulation of Notch signaling by antibodies specific for the extracellular negative regulatory region of NOTCH3. J Biol Chem. 2008 Mar 21; 283(12):8046-54.