"Receptor, Notch4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A notch receptor and proto-oncogene protein characterized by a large extracellular domain that consists of 29 EPIDERMAL GROWTH FACTOR - like repeat sequences (EGF repeats) and five ANKYRIN REPEATS. It functions as a receptor for SERRATE-JAGGED PROTEINS and Delta1 (DLK1) protein to control cell fate determination.
| Descriptor ID |
D000074562
|
| MeSH Number(s) |
D12.776.543.750.725.937 D12.776.624.664.700.815 D12.776.930.770.937
|
| Concept/Terms |
Receptor, Notch4- Receptor, Notch4
- Notch4 Receptor
- Notch4 Protein
- Notch-4 Protein
- Notch 4 Protein
- Notch-4 Receptor
- Notch 4 Receptor
- Receptor, Notch-4
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Notch4".
Below are MeSH descriptors whose meaning is more specific than "Receptor, Notch4".
This graph shows the total number of publications written about "Receptor, Notch4" by people in this website by year, and whether "Receptor, Notch4" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Receptor, Notch4" by people in Profiles.
-
Identifying genetic factors that contribute to the increased risk of congenital heart defects in infants with Down syndrome. Sci Rep. 2020 10 22; 10(1):18051.
-
Notch-1 and notch-4 receptors as prognostic markers in breast cancer. Int J Surg Pathol. 2011 Oct; 19(5):607-13.
-
Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches. Cancer Res. 2008 Jul 01; 68(13):5226-35.
-
A notch1 ectodomain construct inhibits endothelial notch signaling, tumor growth, and angiogenesis. Cancer Res. 2008 Jun 15; 68(12):4727-35.
-
Modest evidence for linkage and possible confirmation of association between NOTCH4 and schizophrenia in a large Veterans Affairs Cooperative Study sample. Am J Med Genet B Neuropsychiatr Genet. 2003 Apr 01; 118B(1):8-15.