 Growth Differentiation Factor 2
"Growth Differentiation Factor 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A growth differentiation factor that plays a regulatory role as a paracrine factor for a diverse array of cell types during EMBRYONIC DEVELOPMENT and in the adult tissues. Growth differentiation factor 2 is also a potent regulator of CHONDROGENESIS and was previously referred to as bone morphogenetic protein 9.
| Descriptor ID |
D055427
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| MeSH Number(s) |
D12.644.276.954.200.910 D12.644.276.954.300.200 D12.776.467.942.200.910 D12.776.467.942.300.200 D23.529.942.200.910 D23.529.942.300.200
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Growth Differentiation Factor 2".
Below are MeSH descriptors whose meaning is more specific than "Growth Differentiation Factor 2".
This graph shows the total number of publications written about "Growth Differentiation Factor 2" by people in this website by year, and whether "Growth Differentiation Factor 2" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2004 | 0 | 3 | 3 | | 2007 | 0 | 1 | 1 | | 2008 | 2 | 0 | 2 | | 2010 | 3 | 0 | 3 | | 2011 | 1 | 0 | 1 | | 2012 | 3 | 1 | 4 | | 2013 | 4 | 0 | 4 | | 2014 | 2 | 0 | 2 | | 2015 | 2 | 0 | 2 | | 2016 | 1 | 0 | 1 | | 2017 | 3 | 2 | 5 |
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Below are the most recent publications written about "Growth Differentiation Factor 2" by people in Profiles.
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Wang T, Zhang Z, Wang K, Wang J, Jiang Y, Xia J, Gou L, Liu M, Zhou L, He T, Zhang Y. Inhibitory effects of BMP9 on breast cancer cells by regulating their interaction with pre-adipocytes/adipocytes. Oncotarget. 2017 May 30; 8(22):35890-35901.
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Zou Y, Qazvini NT, Zane K, Sadati M, Wei Q, Liao J, Fan J, Song D, Liu J, Ma C, Qu X, Chen L, Yu X, Zhang Z, Zhao C, Zeng Z, Zhang R, Yan S, Wu T, Wu X, Shu Y, Li Y, Zhang W, Reid RR, Lee MJ, Wolf JM, Tirrell M, He TC, de Pablo JJ, Deng ZL. Gelatin-Derived Graphene-Silicate Hybrid Materials Are Biocompatible and Synergistically Promote BMP9-Induced Osteogenic Differentiation of Mesenchymal Stem Cells. ACS Appl Mater Interfaces. 2017 May 17; 9(19):15922-15932.
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Wei Q, Fan J, Liao J, Zou Y, Song D, Liu J, Cui J, Liu F, Ma C, Hu X, Li L, Yu Y, Qu X, Chen L, Yu X, Zhang Z, Zhao C, Zeng Z, Zhang R, Yan S, Wu X, Shu Y, Reid RR, Lee MJ, Wolf JM, He TC. Engineering the Rapid Adenovirus Production and Amplification (RAPA) Cell Line to Expedite the Generation of Recombinant Adenoviruses. Cell Physiol Biochem. 2017; 41(6):2383-2398.
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Liao J, Wei Q, Zou Y, Fan J, Song D, Cui J, Zhang W, Zhu Y, Ma C, Hu X, Qu X, Chen L, Yu X, Zhang Z, Wang C, Zhao C, Zeng Z, Zhang R, Yan S, Wu T, Wu X, Shu Y, Lei J, Li Y, Luu HH, Lee MJ, Reid RR, Ameer GA, Wolf JM, He TC, Huang W. Notch Signaling Augments BMP9-Induced Bone Formation by Promoting the Osteogenesis-Angiogenesis Coupling Process in Mesenchymal Stem Cells (MSCs). Cell Physiol Biochem. 2017; 41(5):1905-1923.
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Wang J, Liao J, Zhang F, Song D, Lu M, Liu J, Wei Q, Tang S, Liu H, Fan J, Zou Y, Guo D, Huang J, Liu F, Ma C, Hu X, Li L, Qu X, Chen L, Weng Y, Lee MJ, He TC, Reid RR, Zhang J. NEL-Like Molecule-1 (Nell1) Is Regulated by Bone Morphogenetic Protein 9 (BMP9) and Potentiates BMP9-Induced Osteogenic Differentiation at the Expense of Adipogenesis in Mesenchymal Stem Cells. Cell Physiol Biochem. 2017; 41(2):484-500.
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Li R, Yan Z, Ye J, Huang H, Wang Z, Wei Q, Wang J, Zhao L, Lu S, Wang X, Tang S, Fan J, Zhang F, Zou Y, Song D, Liao J, Lu M, Liu F, Shi LL, Athiviraham A, Lee MJ, He TC, Zhang Z. The Prodomain-Containing BMP9 Produced from a Stable Line Effectively Regulates the Differentiation of Mesenchymal Stem Cells. Int J Med Sci. 2016; 13(1):8-18.
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Li L, Dong Q, Wang Y, Feng Q, Zhou P, Ou X, Meng Q, He T, Luo J. Hedgehog signaling is involved in the BMP9-induced osteogenic differentiation of mesenchymal stem cells. Int J Mol Med. 2015 Jun; 35(6):1641-50.
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Zhang H, Li L, Dong Q, Wang Y, Feng Q, Ou X, Zhou P, He T, Luo J. Activation of PKA/CREB Signaling is Involved in BMP9-Induced Osteogenic Differentiation of Mesenchymal Stem Cells. Cell Physiol Biochem. 2015; 37(2):548-62.
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Wang J, Zhang H, Zhang W, Huang E, Wang N, Wu N, Wen S, Chen X, Liao Z, Deng F, Yin L, Zhang J, Zhang Q, Yan Z, Liu W, Zhang Z, Ye J, Deng Y, Luu HH, Haydon RC, He TC, Deng F. Bone morphogenetic protein-9 effectively induces osteo/odontoblastic differentiation of the reversibly immortalized stem cells of dental apical papilla. Stem Cells Dev. 2014 Jun 15; 23(12):1405-16.
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Li R, Zhang W, Cui J, Shui W, Yin L, Wang Y, Zhang H, Wang N, Wu N, Nan G, Chen X, Wen S, Deng F, Zhang H, Zhou G, Liao Z, Zhang J, Zhang Q, Yan Z, Liu W, Zhang Z, Ye J, Deng Y, Luu HH, Haydon RC, He TC, Deng ZL. Targeting BMP9-promoted human osteosarcoma growth by inactivation of notch signaling. Curr Cancer Drug Targets. 2014; 14(3):274-85.
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