"MicroRNAs" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer, that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC) of target RNA by binding to homologous 3'UTR region as an imperfect match. The small temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered, and are from a class of miRNAs involved in developmental timing.
| Descriptor ID |
D035683
|
| MeSH Number(s) |
D13.150.650.319 D13.444.735.150.319 D13.444.735.790.552.500
|
| Concept/Terms |
MicroRNAs- MicroRNAs
- MicroRNA
- miRNAs
- Micro RNA
- RNA, Micro
- miRNA
Primary MicroRNA- Primary MicroRNA
- MicroRNA, Primary
- Primary miRNA
- miRNA, Primary
- pri-miRNA
- pri miRNA
|
Below are MeSH descriptors whose meaning is more general than "MicroRNAs".
Below are MeSH descriptors whose meaning is more specific than "MicroRNAs".
This graph shows the total number of publications written about "MicroRNAs" by people in this website by year, and whether "MicroRNAs" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2004 | 2 | 0 | 2 |
| 2005 | 3 | 0 | 3 |
| 2006 | 1 | 1 | 2 |
| 2007 | 5 | 4 | 9 |
| 2008 | 11 | 4 | 15 |
| 2009 | 16 | 4 | 20 |
| 2010 | 12 | 6 | 18 |
| 2011 | 16 | 5 | 21 |
| 2012 | 31 | 6 | 37 |
| 2013 | 13 | 8 | 21 |
| 2014 | 30 | 12 | 42 |
| 2015 | 26 | 8 | 34 |
| 2016 | 23 | 7 | 30 |
| 2017 | 15 | 11 | 26 |
| 2018 | 13 | 6 | 19 |
| 2019 | 11 | 5 | 16 |
| 2020 | 9 | 5 | 14 |
| 2021 | 17 | 7 | 24 |
| 2022 | 10 | 1 | 11 |
| 2023 | 13 | 0 | 13 |
| 2024 | 5 | 0 | 5 |
| 2025 | 7 | 1 | 8 |
To return to the timeline,
click here.
Below are the most recent publications written about "MicroRNAs" by people in Profiles.
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Cellular hierarchies of embryonal tumors with multilayered rosettes are shaped by oncogenic microRNAs and receptor-ligand interactions. Nat Cancer. 2025 Jun; 6(6):1035-1055.
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Tracking the Response to Immunotherapy: Blood microRNA Dynamics in Patients With Advanced Non-Small Cell Lung Cancer. JCO Precis Oncol. 2025 May; 9:e2400790.
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Diagnostic MicroRNA Signatures to Support Classification of Pulmonary Hypertension. Circ Genom Precis Med. 2025 Jun; 18(3):e004862.
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Plasma Levels of MicroRNA Let-7c-5p May Predict Risk of Acute Chest Syndrome in Patients with Sickle Cell Disease. Int J Mol Sci. 2025 Apr 18; 26(8).
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A Systematic Review of MicroRNAs in Hemorrhagic Neurovascular Disease: Cerebral Cavernous Malformations as a Paradigm. Int J Mol Sci. 2025 Apr 17; 26(8).
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Paternal heroin self-administration in rats increases drug-seeking behavior in male offspring via miR-19b downregulation in the nucleus accumbens. Neuropsychopharmacology. 2025 Jun; 50(7):1027-1038.
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Adapted Exosomes for Addressing Chemotherapy-induced Premature Ovarian Insufficiency. Stem Cell Rev Rep. 2025 Apr; 21(3):779-796.
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Characterization and molecular targeting of CFIm25 (NUDT21/CPSF5) mRNA using miRNAs. FASEB J. 2025 Jan 31; 39(2):e70324.
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Evaluating the clinical performance of an updated microRNA classifier in indeterminate and RAS-mutated thyroid nodule management: A multi-institutional study. Surgery. 2025 01; 177:108833.
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MicroRNA-based engineered mesenchymal stem cell extracellular vesicles to treat visual deficits after blast-induced trauma. Exp Eye Res. 2024 Oct; 247:110031.