 Alzheimer Disease
"Alzheimer Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Descriptor ID |
D000544
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| MeSH Number(s) |
C10.228.140.380.100 C10.574.945.249 F03.087.400.100
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| Concept/Terms |
Alzheimer Disease- Alzheimer Disease
- Disease, Alzheimer
- Alzheimer's Disease
- Disease, Alzheimer's
- Primary Senile Degenerative Dementia
- Dementia, Alzheimer Type
- Alzheimer Type Dementia
- Senile Dementia, Alzheimer Type
- Alzheimer Type Senile Dementia
- Dementia, Primary Senile Degenerative
- Dementia, Senile
- Dementias, Senile
- Senile Dementia
- Senile Dementias
Dementia, Presenile- Dementia, Presenile
- Dementias, Presenile
- Presenile Dementia
- Presenile Dementias
Alzheimer Disease, Early Onset- Alzheimer Disease, Early Onset
- Early Onset Alzheimer Disease
- Presenile Alzheimer Dementia
- Alzheimer Dementia, Presenile
- Dementia, Presenile Alzheimer
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Below are MeSH descriptors whose meaning is more general than "Alzheimer Disease".
Below are MeSH descriptors whose meaning is more specific than "Alzheimer Disease".
This graph shows the total number of publications written about "Alzheimer Disease" by people in this website by year, and whether "Alzheimer Disease" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 1 | 0 | 1 | | 1985 | 1 | 1 | 2 | | 1988 | 3 | 0 | 3 | | 1989 | 1 | 0 | 1 | | 1990 | 5 | 0 | 5 | | 1991 | 10 | 0 | 10 | | 1992 | 6 | 1 | 7 | | 1993 | 6 | 3 | 9 | | 1994 | 8 | 3 | 11 | | 1995 | 4 | 3 | 7 | | 1996 | 13 | 1 | 14 | | 1997 | 10 | 3 | 13 | | 1998 | 8 | 8 | 16 | | 1999 | 10 | 2 | 12 | | 2000 | 6 | 5 | 11 | | 2001 | 4 | 4 | 8 | | 2002 | 8 | 3 | 11 | | 2003 | 7 | 4 | 11 | | 2004 | 11 | 0 | 11 | | 2005 | 10 | 5 | 15 | | 2006 | 8 | 3 | 11 | | 2007 | 5 | 2 | 7 | | 2008 | 2 | 6 | 8 | | 2009 | 2 | 1 | 3 | | 2010 | 6 | 5 | 11 | | 2011 | 3 | 5 | 8 | | 2012 | 2 | 1 | 3 | | 2013 | 11 | 0 | 11 | | 2014 | 1 | 1 | 2 | | 2015 | 0 | 2 | 2 | | 2016 | 3 | 2 | 5 | | 2017 | 9 | 1 | 10 | | 2018 | 7 | 1 | 8 | | 2019 | 6 | 1 | 7 | | 2020 | 5 | 0 | 5 | | 2021 | 6 | 2 | 8 | | 2022 | 4 | 0 | 4 |
To return to the timeline, click here.
Below are the most recent publications written about "Alzheimer Disease" by people in Profiles.
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Eissman JM, Dumitrescu L, Mahoney ER, Smith AN, Mukherjee S, Lee ML, Scollard P, Choi SE, Bush WS, Engelman CD, Lu Q, Fardo DW, Trittschuh EH, Mez J, Kaczorowski CC, Hernandez Saucedo H, Widaman KF, Buckley RF, Properzi MJ, Mormino EC, Yang HS, Harrison TM, Hedden T, Nho K, Andrews SJ, Tommet D, Hadad N, Sanders RE, Ruderfer DM, Gifford KA, Zhong X, Raghavan NS, Vardarajan BN. Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease. Brain. 2022 07 29; 145(7):2541-2554.
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Kay LM. COVID-19 and olfactory dysfunction: a looming wave of dementia? J Neurophysiol. 2022 08 01; 128(2):436-444.
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Shafik AM, Zhou H, Lim J, Dickinson B, Jin P. Dysregulated mitochondrial and cytosolic tRNA m1A methylation in Alzheimer's disease. Hum Mol Genet. 2022 05 19; 31(10):1673-1680.
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Sudwarts A, Ramesha S, Gao T, Ponnusamy M, Wang S, Hansen M, Kozlova A, Bitarafan S, Kumar P, Beaulieu-Abdelahad D, Zhang X, Collier L, Szekeres C, Wood LB, Duan J, Thinakaran G, Rangaraju S. BIN1 is a key regulator of proinflammatory and neurodegeneration-related activation in microglia. Mol Neurodegener. 2022 05 07; 17(1):33.
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Sun Y, Zhou D, Rahman MR, Zhu J, Ghoneim D, Cox NJ, Beach TG, Wu C, Gamazon ER, Wu L. A transcriptome-wide association study identifies novel blood-based gene biomarker candidates for Alzheimer's disease risk. Hum Mol Genet. 2021 12 27; 31(2):289-299.
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Kedia S, Mandal K, Netrakanti PR, Jose M, Sisodia SS, Nair D. Nanoscale organization of Nicastrin, the substrate receptor of the ?-secretase complex, as independent molecular domains. Mol Brain. 2021 10 13; 14(1):158.
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Jicha GA, Abner EL, Arnold SE, Carrillo MC, Dodge HH, Edland SD, Fargo KN, Feldman HH, Goldstein LB, Hendrix J, Peters R, Robillard JM, Schneider LS, Titiner JR, Weber CJ. Committee on High-quality Alzheimer's Disease Studies (CHADS) consensus report. Alzheimers Dement. 2022 06; 18(6):1109-1118.
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Hollenbeck BK, Dunn RL, Sukul D, Modi PK, Nallamothu BK, Sen A, Bynum JP. Aortic valve replacement among patients with Alzheimer's disease and related dementias. J Am Geriatr Soc. 2021 12; 69(12):3468-3475.
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Sun Y, Zhu J, Zhou D, Canchi S, Wu C, Cox NJ, Rissman RA, Gamazon ER, Wu L. A transcriptome-wide association study of Alzheimer's disease using prediction models of relevant tissues identifies novel candidate susceptibility genes. Genome Med. 2021 09 01; 13(1):141.
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Wang S, Yan D, Temkin-Greener H, Cai S. Nursing home admissions for persons with dementia: Role of home- and community-based services. Health Serv Res. 2021 12; 56(6):1168-1178.
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