 Alzheimer Disease
"Alzheimer Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Descriptor ID |
D000544
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| MeSH Number(s) |
C10.228.140.380.100 C10.574.945.249 F03.087.400.100
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| Concept/Terms |
Alzheimer Disease- Alzheimer Disease
- Disease, Alzheimer
- Alzheimer's Disease
- Disease, Alzheimer's
- Primary Senile Degenerative Dementia
- Dementia, Alzheimer Type
- Alzheimer Type Dementia
- Senile Dementia, Alzheimer Type
- Alzheimer Type Senile Dementia
- Dementia, Primary Senile Degenerative
- Dementia, Senile
- Dementias, Senile
- Senile Dementia
- Senile Dementias
Dementia, Presenile- Dementia, Presenile
- Dementias, Presenile
- Presenile Dementia
- Presenile Dementias
Alzheimer Disease, Early Onset- Alzheimer Disease, Early Onset
- Early Onset Alzheimer Disease
- Presenile Alzheimer Dementia
- Alzheimer Dementia, Presenile
- Dementia, Presenile Alzheimer
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Below are MeSH descriptors whose meaning is more general than "Alzheimer Disease".
Below are MeSH descriptors whose meaning is more specific than "Alzheimer Disease".
This graph shows the total number of publications written about "Alzheimer Disease" by people in this website by year, and whether "Alzheimer Disease" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 1 | 0 | 1 | | 1985 | 1 | 1 | 2 | | 1988 | 3 | 0 | 3 | | 1989 | 1 | 0 | 1 | | 1990 | 5 | 0 | 5 | | 1991 | 10 | 0 | 10 | | 1992 | 6 | 1 | 7 | | 1993 | 6 | 3 | 9 | | 1994 | 8 | 3 | 11 | | 1995 | 4 | 3 | 7 | | 1996 | 13 | 1 | 14 | | 1997 | 10 | 3 | 13 | | 1998 | 8 | 8 | 16 | | 1999 | 10 | 2 | 12 | | 2000 | 7 | 5 | 12 | | 2001 | 5 | 4 | 9 | | 2002 | 8 | 3 | 11 | | 2003 | 7 | 5 | 12 | | 2004 | 11 | 1 | 12 | | 2005 | 9 | 5 | 14 | | 2006 | 8 | 3 | 11 | | 2007 | 5 | 2 | 7 | | 2008 | 3 | 6 | 9 | | 2009 | 2 | 1 | 3 | | 2010 | 7 | 5 | 12 | | 2011 | 4 | 5 | 9 | | 2012 | 2 | 1 | 3 | | 2013 | 10 | 2 | 12 | | 2014 | 4 | 1 | 5 | | 2015 | 1 | 3 | 4 | | 2016 | 5 | 4 | 9 | | 2017 | 10 | 1 | 11 | | 2018 | 7 | 2 | 9 |
To return to the timeline, click here.
Below are the most recent publications written about "Alzheimer Disease" by people in Profiles.
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Kai C, Uchiyama Y, Shiraishi J, Fujita H. [Quantitation of Cerebral Atrophy due to Normal Aging: Principal Component Analysis with MR Images in Patients' Age Groups]. Nihon Hoshasen Gijutsu Gakkai Zasshi. 2018 12; 74(12):1389-1395.
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Deming Y, Dumitrescu L, Barnes LL, Thambisetty M, Kunkle B, Gifford KA, Bush WS, Chibnik LB, Mukherjee S, De Jager PL, Kukull W, Huentelman M, Crane PK, Resnick SM, Keene CD, Montine TJ, Schellenberg GD, Haines JL, Zetterberg H, Blennow K, Larson EB, Johnson SC, Albert M, Moghekar A, Del Aguila JL, Fernandez MV, Budde J, Hassenstab J, Fagan AM, Riemenschneider M, Petersen RC, Minthon L, Chao MJ, Van Deerlin VM, Lee VM, Shaw LM, Trojanowski JQ, Peskind ER, Li G, Davis LK, Sealock JM, Cox NJ. Sex-specific genetic predictors of Alzheimer's disease biomarkers. Acta Neuropathol. 2018 12; 136(6):857-872.
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Musial TF, Molina-Campos E, Bean LA, Ybarra N, Borenstein R, Russo ML, Buss EW, Justus D, Neuman KM, Ayala GD, Mullen SA, Voskobiynyk Y, Tulisiak CT, Fels JA, Corbett NJ, Carballo G, Kennedy CD, Popovic J, Ramos-Franco J, Fill M, Pergande MR, Borgia JA, Corbett GT, Pahan K, Han Y, Chetkovich DM, Vassar RJ, Byrne RW, Matthew Oh M, Stoub TR, Remy S, Disterhoft JF, Nicholson DA. Store depletion-induced h-channel plasticity rescues a channelopathy linked to Alzheimer's disease. Neurobiol Learn Mem. 2018 10; 154:141-157.
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Chung J, Phukan G, Vergote D, Mohamed A, Maulik M, Stahn M, Andrew RJ, Thinakaran G, Posse de Chaves E, Kar S. Endosomal-Lysosomal Cholesterol Sequestration by U18666A Differentially Regulates Amyloid Precursor Protein (APP) Metabolism in Normal and APP-Overexpressing Cells. Mol Cell Biol. 2018 06 01; 38(11).
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Kai C, Uchiyama Y, Shiraishi J, Fujita H, Doi K. Computer-aided diagnosis with radiogenomics: analysis of the relationship between genotype and morphological changes of the brain magnetic resonance images. Radiol Phys Technol. 2018 Sep; 11(3):265-273.
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McAninch EA, Rajan KB, Evans DA, Jo S, Chaker L, Peeters RP, Bennett DA, Mash DC, Bianco AC. A Common DIO2 Polymorphism and Alzheimer Disease Dementia in African and European Americans. J Clin Endocrinol Metab. 2018 05 01; 103(5):1818-1826.
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Zimmermann J, Perry A, Breakspear M, Schirner M, Sachdev P, Wen W, Kochan NA, Mapstone M, Ritter P, McIntosh AR, Solodkin A. Differentiation of Alzheimer's disease based on local and global parameters in personalized Virtual Brain models. Neuroimage Clin. 2018; 19:240-251.
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Sun R, He T, Pan Y, Katusic ZS. Effects of senescence and angiotensin II on expression and processing of amyloid precursor protein in human cerebral microvascular endothelial cells. Aging (Albany NY). 2018 01 15; 10(1):100-114.
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Al-Janabi OM, Brown CA, Bahrani AA, Abner EL, Barber JM, Gold BT, Goldstein LB, Murphy RR, Nelson PT, Johnson NF, Shaw LM, Smith CD, Trojanowski JQ, Wilcock DM, Jicha GA. Distinct White Matter Changes Associated with Cerebrospinal Fluid Amyloid-ß1-42 and Hypertension. J Alzheimers Dis. 2018; 66(3):1095-1104.
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Gerlach RM, Chaney MA. Postoperative cognitive dysfunction related to Alzheimer disease? J Thorac Cardiovasc Surg. 2018 03; 155(3):968-969.
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