 Baclofen
"Baclofen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A GAMMA-AMINOBUTYRIC ACID derivative that is a specific agonist of GABA-B RECEPTORS. It is used in the treatment of MUSCLE SPASTICITY, especially that due to SPINAL CORD INJURIES. Its therapeutic effects result from actions at spinal and supraspinal sites, generally the reduction of excitatory transmission.
| Descriptor ID |
D001418
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| MeSH Number(s) |
D02.241.081.160.050.350.100
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| Concept/Terms |
Baclofen- Baclofen
- PCP-GABA
- beta-(p-Chlorophenyl)-gamma-aminobutyric Acid
- Chlorophenyl GABA
- GABA, Chlorophenyl
- Baclophen
- beta-(Aminomethyl)-4-chlorobenzenepropanoic Acid
Atrofen- Atrofen
- Athena Brand of Baclofen
- Baclofen Athena Brand
Ba-34,647- Ba-34,647
- Ba34,647
- CIBA-34,647-BA
- CIBA34,647BA
- Ba-34647
- Ba34647
Baclofen AWD- Baclofen AWD
- AWD, Baclofen
- ASTA Medica Brand of Baclofen
Baclofène-Irex- Baclofène-Irex
- Baclofène Irex
- BaclofèneIrex
- Irex Brand of Baclofen
- Baclofen Irex Brand
PMS-Baclofen- PMS-Baclofen
- PMS Baclofen
- PMSBaclofen
- Pharmascience Brand of Baclofen
- Baclofen Pharmascience Brand
Clofen- Clofen
- Alphapharm Brand of Baclofen
- Baclofen Alphapharm Brand
Lebic- Lebic
- Isis Brand of Baclofen
- Baclofen Isis Brand
Lioresal- Lioresal
- Novartis Brand of Baclofen
- Baclofen Novartis Brand
- Liorésal
- Ciba-Geigy Brand of Baclofen
- Baclofen Ciba-Geigy Brand
- Ciba Geigy Brand of Baclofen
- Medtronic Brand of Baclofen
- Baclofen Medtronic Brand
Nu-Baclo- Nu-Baclo
- Nu Baclo
- NuBaclo
- Nu-Pharm Brand of Baclofen
- Baclofen Nu-Pharm Brand
- Nu Pharm Brand of Baclofen
Apo-Baclofen- Apo-Baclofen
- Apo Baclofen
- ApoBaclofen
- Apotex Brand of Baclofen
- Baclofen Apotex Brand
Baclospas- Baclospas
- Ashbourne Brand of Baclofen
- Baclofen Ashbourne Brand
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Below are MeSH descriptors whose meaning is more general than "Baclofen".
Below are MeSH descriptors whose meaning is more specific than "Baclofen".
This graph shows the total number of publications written about "Baclofen" by people in this website by year, and whether "Baclofen" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1990 | 1 | 0 | 1 | | 1991 | 1 | 0 | 1 | | 1992 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 1999 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2002 | 1 | 1 | 2 | | 2004 | 0 | 1 | 1 | | 2005 | 3 | 1 | 4 | | 2010 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 | | 2012 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2015 | 0 | 1 | 1 | | 2016 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Baclofen" by people in Profiles.
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Veenstra-VanderWeele J, Cook EH, King BH, Zarevics P, Cherubini M, Walton-Bowen K, Bear MF, Wang PP, Carpenter RL. Arbaclofen in Children and Adolescents with Autism Spectrum Disorder: A Randomized, Controlled, Phase 2 Trial. Neuropsychopharmacology. 2017 Jun; 42(7):1390-1398.
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Pan IW, Kuo GM, Luerssen TG, Lam SK. Impact of antibiotic prophylaxis for intrathecal baclofen pump surgery in pediatric patients. Neurosurg Focus. 2015 Dec; 39(6):E10.
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Erickson CA, Veenstra-Vanderweele JM, Melmed RD, McCracken JT, Ginsberg LD, Sikich L, Scahill L, Cherubini M, Zarevics P, Walton-Bowen K, Carpenter RL, Bear MF, Wang PP, King BH. STX209 (arbaclofen) for autism spectrum disorders: an 8-week open-label study. J Autism Dev Disord. 2014 Apr; 44(4):958-64.
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Berry-Kravis EM, Hessl D, Rathmell B, Zarevics P, Cherubini M, Walton-Bowen K, Mu Y, Nguyen DV, Gonzalez-Heydrich J, Wang PP, Carpenter RL, Bear MF, Hagerman RJ. Effects of STX209 (arbaclofen) on neurobehavioral function in children and adults with fragile X syndrome: a randomized, controlled, phase 2 trial. Sci Transl Med. 2012 Sep 19; 4(152):152ra127.
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Bello EP, Mateo Y, Gelman DM, Noaín D, Shin JH, Low MJ, Alvarez VA, Lovinger DM, Rubinstein M. Cocaine supersensitivity and enhanced motivation for reward in mice lacking dopamine D2 autoreceptors. Nat Neurosci. 2011 Jul 10; 14(8):1033-8.
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Lee R, Chong B, Coccaro E. Growth hormone responses to GABAB receptor challenge with baclofen and impulsivity in healthy control and personality disorder subjects. Psychopharmacology (Berl). 2011 May; 215(1):41-8.
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Heskin-Sweezie R, Titley HK, Baizer JS, Broussard DM. Type B GABA receptors contribute to the restoration of balance during vestibular compensation in mice. Neuroscience. 2010 Aug 11; 169(1):302-14.
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Hain TC. Head-shaking nystagmus and new technology. Neurology. 2007 Apr 24; 68(17):1333-4.
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Homer JR, Davies JM, Amundsen LB. Persistent hiccups after attempted interscalene brachial plexus block. Reg Anesth Pain Med. 2005 Nov-Dec; 30(6):574-6.
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Lagarce F, Faisant N, Desfontis JC, Marescaux L, Gautier F, Holopherne D, Rousselet MC, Menei P, Benoit JP. Biopharmaceutics of intrathecal baclofen-loaded microparticles in a goat model. Int J Pharm. 2005 Jul 14; 298(1):68-79.
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