Rho Guanine Nucleotide Exchange Factors
"Rho Guanine Nucleotide Exchange Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Signaling proteins which function as master molecular switches by activating Rho GTPases through conversion of guanine nucleotides. Rho GTPases in turn control many aspects of cell behavior through the regulation of multiple downstream signal transduction pathways.
| Descriptor ID |
D064067
|
| MeSH Number(s) |
D12.644.360.325.300.099 D12.776.476.325.300.099
|
| Concept/Terms |
Rho Guanine Nucleotide Exchange Factor 7- Rho Guanine Nucleotide Exchange Factor 7
- PAK-Interacting Exchange Factor beta
- PAK Interacting Exchange Factor beta
- Cool-1 Protein
- Cool 1 Protein
- Protein, Cool-1
- beta PIX Protein
- PIX Protein, beta
- Protein, beta PIX
- betaPIX Protein
- Protein, betaPIX
|
Below are MeSH descriptors whose meaning is more general than "Rho Guanine Nucleotide Exchange Factors".
Below are MeSH descriptors whose meaning is more specific than "Rho Guanine Nucleotide Exchange Factors".
This graph shows the total number of publications written about "Rho Guanine Nucleotide Exchange Factors" by people in this website by year, and whether "Rho Guanine Nucleotide Exchange Factors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 1 | 2 |
| 2009 | 0 | 3 | 3 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 2 | 1 | 3 |
| 2016 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "Rho Guanine Nucleotide Exchange Factors" by people in Profiles.
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Aurora A and cortical flows promote polarization and cytokinesis by inducing asymmetric ECT-2 accumulation. Elife. 2022 12 19; 11.
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Associations between antenatal maternal asthma status and placental DNA methylation. Placenta. 2022 08; 126:184-195.
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Spatiotemporal Regulation of RhoA during Cytokinesis. Curr Biol. 2018 05 07; 28(9):R570-R580.
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Myofilaments: Movers and Rulers of the Sarcomere. Compr Physiol. 2017 03 16; 7(2):675-692.
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Modulation of Endothelial Inflammation by Low and High Magnitude Cyclic Stretch. PLoS One. 2016; 11(4):e0153387.
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Asef mediates HGF protective effects against LPS-induced lung injury and endothelial barrier dysfunction. Am J Physiol Lung Cell Mol Physiol. 2015 Mar 01; 308(5):L452-63.
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Asef controls vascular endothelial permeability and barrier recovery in the lung. Mol Biol Cell. 2015 Feb 15; 26(4):636-50.
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Hepatocyte growth factor-induced Asef-IQGAP1 complex controls cytoskeletal remodeling and endothelial barrier. J Biol Chem. 2015 Feb 13; 290(7):4097-109.
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Hepatocyte growth factor triggers distinct mechanisms of Asef and Tiam1 activation to induce endothelial barrier enhancement. Cell Signal. 2014 Nov; 26(11):2306-16.
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Stiffness-activated GEF-H1 expression exacerbates LPS-induced lung inflammation. PLoS One. 2014; 9(4):e92670.