3-Phosphoinositide-Dependent Protein Kinases
"3-Phosphoinositide-Dependent Protein Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Highly conserved protein-serine threonine kinases that phosphorylate and activate a group of AGC protein kinases, especially in response to the production of the SECOND MESSENGERS, phosphatidylinositol 3,4,-biphosphate (PtdIns(3,4)P2) and phosphatidylinositol 3,4,5-triphosphate (PtdIns(3,4,5)P3).
| Descriptor ID |
D064413
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| MeSH Number(s) |
D08.811.913.696.620.682.700.745
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| Concept/Terms |
3-Phosphoinositide-Dependent Protein Kinases- 3-Phosphoinositide-Dependent Protein Kinases
- 3 Phosphoinositide Dependent Protein Kinases
- Kinases, 3-Phosphoinositide-Dependent Protein
- Protein Kinases, 3-Phosphoinositide-Dependent
- 3-Phosphoinositide-Dependent Protein Kinase
- 3 Phosphoinositide Dependent Protein Kinase
- Kinase, 3-Phosphoinositide-Dependent Protein
- Protein Kinase, 3-Phosphoinositide-Dependent
3-Phosphoinositide Dependent Protein Kinase-1- 3-Phosphoinositide Dependent Protein Kinase-1
- 3 Phosphoinositide Dependent Protein Kinase 1
- 3-Phosphoinositide-Dependent Protein Kinase-1
- Kinase-1, 3-Phosphoinositide-Dependent Protein
- Protein Kinase-1, 3-Phosphoinositide-Dependent
- PtdIns(3,4,5)P3-Dependent Protein Kinase-1
- 3-Phosphoinositide-Dependent Kinase 1 (PDK1)
3-Phosphoinositide Dependent Protein Kinase-2- 3-Phosphoinositide Dependent Protein Kinase-2
- 3 Phosphoinositide Dependent Protein Kinase 2
- 3-Phosphoinositide-Dependent Protein Kinase-2
- Kinase-2, 3-Phosphoinositide-Dependent Protein
- Protein Kinase-2, 3-Phosphoinositide-Dependent
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Below are MeSH descriptors whose meaning is more general than "3-Phosphoinositide-Dependent Protein Kinases".
Below are MeSH descriptors whose meaning is more specific than "3-Phosphoinositide-Dependent Protein Kinases".
This graph shows the total number of publications written about "3-Phosphoinositide-Dependent Protein Kinases" by people in this website by year, and whether "3-Phosphoinositide-Dependent Protein Kinases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "3-Phosphoinositide-Dependent Protein Kinases" by people in Profiles.
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The deacetylase SIRT1 promotes membrane localization and activation of Akt and PDK1 during tumorigenesis and cardiac hypertrophy. Sci Signal. 2011 Jul 19; 4(182):ra46.
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Polyunsaturated fatty acids block platelet-activating factor-induced phosphatidylinositol 3 kinase/Akt-mediated apoptosis in intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2008 May; 294(5):G1181-90.
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Decreasing IRS-2 expression in pancreatic beta-cells (INS-1) promotes apoptosis, which can be compensated for by introduction of IRS-4 expression. Mol Cell Endocrinol. 2003 Nov 14; 209(1-2):17-31.
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Involvement of FKHR-dependent TRADD expression in chemotherapeutic drug-induced apoptosis. Mol Cell Biol. 2002 Dec; 22(24):8695-708.
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Different protein kinase C isoforms determine growth factor specificity in neuronal cells. Mol Cell Biol. 2000 Aug; 20(15):5392-403.