 Epidermal Growth Factor
"Epidermal Growth Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 6-kDa polypeptide growth factor initially discovered in mouse submaxillary glands. Human epidermal growth factor was originally isolated from urine based on its ability to inhibit gastric secretion and called urogastrone. EPIDERMAL GROWTH FACTOR exerts a wide variety of biological effects including the promotion of proliferation and differentiation of mesenchymal and epithelial cells.
| Descriptor ID |
D004815
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| MeSH Number(s) |
D06.472.317.350 D12.644.276.561 D12.776.467.561 D23.529.561
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| Concept/Terms |
Epidermal Growth Factor- Epidermal Growth Factor
- Growth Factor, Epidermal
- Human Urinary Gastric Inhibitor
- Epidermal Growth Factor-Urogastrone
- Growth Factor-Urogastrone, Epidermal
- beta-Urogastrone
- beta Urogastrone
- EGF
- Epidermal Growth Factors
- Growth Factors, Epidermal
- Urogastrone
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Below are MeSH descriptors whose meaning is more general than "Epidermal Growth Factor".
Below are MeSH descriptors whose meaning is more specific than "Epidermal Growth Factor".
This graph shows the total number of publications written about "Epidermal Growth Factor" by people in this website by year, and whether "Epidermal Growth Factor" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 2 | 1 | 3 | | 1983 | 0 | 1 | 1 | | 1984 | 2 | 0 | 2 | | 1987 | 2 | 5 | 7 | | 1989 | 2 | 4 | 6 | | 1990 | 5 | 0 | 5 | | 1991 | 4 | 1 | 5 | | 1992 | 3 | 1 | 4 | | 1993 | 1 | 3 | 4 | | 1994 | 2 | 0 | 2 | | 1995 | 0 | 3 | 3 | | 1996 | 1 | 1 | 2 | | 1997 | 0 | 2 | 2 | | 1998 | 1 | 1 | 2 | | 1999 | 0 | 3 | 3 | | 2000 | 2 | 0 | 2 | | 2001 | 0 | 1 | 1 | | 2002 | 1 | 1 | 2 | | 2003 | 2 | 1 | 3 | | 2004 | 1 | 2 | 3 | | 2005 | 0 | 2 | 2 | | 2006 | 1 | 4 | 5 | | 2007 | 1 | 2 | 3 | | 2008 | 2 | 1 | 3 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 4 | 5 | | 2011 | 1 | 2 | 3 | | 2012 | 3 | 0 | 3 | | 2013 | 2 | 2 | 4 | | 2014 | 1 | 1 | 2 | | 2016 | 0 | 3 | 3 | | 2018 | 1 | 1 | 2 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Epidermal Growth Factor" by people in Profiles.
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Menez S, Ju W, Menon R, Moledina DG, Thiessen Philbrook H, McArthur E, Jia Y, Obeid W, Mansour SG, Koyner JL, Shlipak MG, Coca SG, Garg AX, Bomback AS, Kellum JA, Kretzler M, Parikh CR. Urinary EGF and MCP-1 and risk of CKD after cardiac surgery. JCI Insight. 2021 06 08; 6(11).
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Leigh ND, Sessa S, Dragalzew AC, Payzin-Dogru D, Sousa JF, Aggouras AN, Johnson K, Dunlap GS, Haas BJ, Levin M, Schneider I, Whited JL. von Willebrand factor D and EGF domains is an evolutionarily conserved and required feature of blastemas capable of multitissue appendage regeneration. Evol Dev. 2020 07; 22(4):297-311.
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Dubé PE, Liu CY, Girish N, Washington MK, Polk DB. Pharmacological activation of epidermal growth factor receptor signaling inhibits colitis-associated cancer in mice. Sci Rep. 2018 06 14; 8(1):9119.
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Isani M, Illingworth L, Herman E, Schmidt M, Barron L, Bowling J, Elizee M, Bai I, Gayer C, Grishin A, Erwin CR, Ford HR, Warner BW. Soybean-derived recombinant human epidermal growth factor protects against experimental necrotizing enterocolitis. J Pediatr Surg. 2018 Jun; 53(6):1203-1207.
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Guzy RD, Li L, Smith C, Dorry SJ, Koo HY, Chen L, Ornitz DM. Pulmonary fibrosis requires cell-autonomous mesenchymal fibroblast growth factor (FGF) signaling. J Biol Chem. 2017 06 23; 292(25):10364-10378.
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Fan J, Lin R, Xia S, Chen D, Elf SE, Liu S, Pan Y, Xu H, Qian Z, Wang M, Shan C, Zhou L, Lei QY, Li Y, Mao H, Lee BH, Sudderth J, DeBerardinis RJ, Zhang G, Owonikoko T, Gaddh M, Arellano ML, Khoury HJ, Khuri FR, Kang S, Doetsch PW, Lonial S, Boggon TJ, Curran WJ, Chen J. Tetrameric Acetyl-CoA Acetyltransferase 1 Is Important for Tumor Growth. Mol Cell. 2016 12 01; 64(5):859-874.
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Wang L, Wang X, Zhu XM, Liu YQ, Du WJ, Ji J, He X, Zhang CF, Li F, Guo CR, Wang CZ, Yuan CS. Gastroprotective Effect of Alkaloids from Cortex Phellodendri on Gastric Ulcers in Rats through Neurohumoral Regulation. Planta Med. 2017 Feb; 83(3-04):277-284.
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Sheng Z, Yu L, Zhang T, Pei X, Li X, Zhang Z, Du W. ESCRT-0 complex modulates Rbf-mutant cell survival by regulating Rhomboid endosomal trafficking and EGFR signaling. J Cell Sci. 2016 05 15; 129(10):2075-84.
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Fan J, Kang HB, Shan C, Elf S, Lin R, Xie J, Gu TL, Aguiar M, Lonning S, Chung TW, Arellano M, Khoury HJ, Shin DM, Khuri FR, Boggon TJ, Kang S, Chen J. Tyr-301 phosphorylation inhibits pyruvate dehydrogenase by blocking substrate binding and promotes the Warburg effect. J Biol Chem. 2014 Sep 19; 289(38):26533-26541.
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Lennon FE, Mirzapoiazova T, Mambetsariev B, Poroyko VA, Salgia R, Moss J, Singleton PA. The Mu opioid receptor promotes opioid and growth factor-induced proliferation, migration and Epithelial Mesenchymal Transition (EMT) in human lung cancer. PLoS One. 2014; 9(3):e91577.
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