"EGF Family of Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of proteins that are related to epidermal growth factor. They share in common a consensus sequence consisting of six spatially conserved CYSTEINE residues which form three intramolecular bonds. This consensus sequence is commonly referred to EGF motif and is considered essential for binding of the proteins to ERB RECEPTORS.
| Descriptor ID |
D066255
|
| MeSH Number(s) |
D12.644.276.382 D12.776.467.382 D23.529.382
|
| Concept/Terms |
EGF Family of Proteins- EGF Family of Proteins
- Proteins EGF Family
- Epidermal Growth Factors
- EGF Receptor Ligands
- Ligands, EGF Receptor
- Receptor Ligands, EGF
- Epidermal Growth Factor-Like Proteins
- Epidermal Growth Factor Like Proteins
|
Below are MeSH descriptors whose meaning is more general than "EGF Family of Proteins".
Below are MeSH descriptors whose meaning is more specific than "EGF Family of Proteins".
This graph shows the total number of publications written about "EGF Family of Proteins" by people in this website by year, and whether "EGF Family of Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "EGF Family of Proteins" by people in Profiles.
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Ret heterozygous mice have enhanced intestinal adaptation after massive small bowel resection. Am J Physiol Gastrointest Liver Physiol. 2012 May 15; 302(10):G1143-50.
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Human oocyte maturation is dependent on LH-stimulated accumulation of the epidermal growth factor-like growth factor, amphiregulin. Hum Reprod. 2010 Oct; 25(10):2569-78.
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Increases of amphiregulin and transforming growth factor-alpha in serum as predictors of poor response to gefitinib among patients with advanced non-small cell lung cancers. Cancer Res. 2005 Oct 15; 65(20):9176-84.
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Amphiregulin in lung branching morphogenesis: interaction with heparan sulfate proteoglycan modulates cell proliferation. Development. 1996 Jun; 122(6):1759-67.