"Epistasis, Genetic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A form of gene interaction whereby the expression of one gene interferes with or masks the expression of a different gene or genes. Genes whose expression interferes with or masks the effects of other genes are said to be epistatic to the effected genes. Genes whose expression is affected (blocked or masked) are hypostatic to the interfering genes.
| Descriptor ID |
D004843
|
| MeSH Number(s) |
G05.308.207
|
| Concept/Terms |
Epistasis, Genetic- Epistasis, Genetic
- Epistases, Genetic
- Gene-Gene Interactions, Epistatic
- Gene Gene Interactions, Epistatic
- Gene-Gene Interaction, Epistatic
- Epistatic Gene-Gene Interaction
- Epistatic Gene-Gene Interactions
- Gene Gene Interaction, Epistatic
- Interaction, Epistatic Gene-Gene
- Interactions, Epistatic Gene-Gene
- Non-Allelic Gene Interactions
- Gene Interaction, Non-Allelic
- Gene Interactions, Non-Allelic
- Interaction, Non-Allelic Gene
- Interactions, Non-Allelic Gene
- Non Allelic Gene Interactions
- Non-Allelic Gene Interaction
- Genetic Epistasis
- Genetic Epistases
|
Below are MeSH descriptors whose meaning is more general than "Epistasis, Genetic".
Below are MeSH descriptors whose meaning is more specific than "Epistasis, Genetic".
This graph shows the total number of publications written about "Epistasis, Genetic" by people in this website by year, and whether "Epistasis, Genetic" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 3 | 0 | 3 |
| 2004 | 0 | 4 | 4 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 2 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 5 | 5 |
| 2010 | 2 | 2 | 4 |
| 2011 | 2 | 0 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 4 | 4 |
| 2014 | 1 | 3 | 4 |
| 2015 | 2 | 1 | 3 |
| 2016 | 3 | 1 | 4 |
| 2017 | 0 | 2 | 2 |
| 2018 | 2 | 3 | 5 |
| 2019 | 2 | 0 | 2 |
| 2020 | 2 | 0 | 2 |
| 2021 | 1 | 1 | 2 |
| 2022 | 1 | 0 | 1 |
| 2024 | 3 | 0 | 3 |
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click here.
Below are the most recent publications written about "Epistasis, Genetic" by people in Profiles.
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The simplicity of protein sequence-function relationships. Nat Commun. 2024 Sep 11; 15(1):7953.
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Genomic determinants, architecture, and constraints in drought-related traits in Corymbia calophylla. BMC Genomics. 2024 Jun 27; 25(1):640.
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Epistasis facilitates functional evolution in an ancient transcription factor. Elife. 2024 May 20; 12.
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Epistatic drift causes gradual decay of predictability in protein evolution. Science. 2022 05 20; 376(6595):823-830.
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Contingency and chance erase necessity in the experimental evolution of ancestral proteins. Elife. 2021 06 01; 10.
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A model and test for coordinated polygenic epistasis in complex traits. Proc Natl Acad Sci U S A. 2021 04 13; 118(15).
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FUT2-ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses. Nat Commun. 2020 12 16; 11(1):6398.
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Physical Constraints on Epistasis. Mol Biol Evol. 2020 10 01; 37(10):2865-2874.
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Learning the pattern of epistasis linking genotype and phenotype in a protein. Nat Commun. 2019 09 16; 10(1):4213.
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Genetic-Epigenetic Interactions in Asthma Revealed by a Genome-Wide Gene-Centric Search. Hum Hered. 2018; 83(3):130-152.