 Epistasis, Genetic
"Epistasis, Genetic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A form of gene interaction whereby the expression of one gene interferes with or masks the expression of a different gene or genes. Genes whose expression interferes with or masks the effects of other genes are said to be epistatic to the effected genes. Genes whose expression is affected (blocked or masked) are hypostatic to the interfering genes.
| Descriptor ID |
D004843
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| MeSH Number(s) |
G05.355.315.207
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| Concept/Terms |
Epistasis, Genetic- Epistasis, Genetic
- Gene-Gene Interaction, Epistatic
- Epistatic Gene-Gene Interaction
- Epistatic Gene-Gene Interactions
- Gene Gene Interaction, Epistatic
- Interaction, Epistatic Gene-Gene
- Interactions, Epistatic Gene-Gene
- Non-Allelic Gene Interactions
- Gene Interaction, Non-Allelic
- Gene Interactions, Non-Allelic
- Interaction, Non-Allelic Gene
- Interactions, Non-Allelic Gene
- Non Allelic Gene Interactions
- Non-Allelic Gene Interaction
- Genetic Epistases
- Genetic Epistasis
- Epistases, Genetic
- Gene-Gene Interactions, Epistatic
- Gene Gene Interactions, Epistatic
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Below are MeSH descriptors whose meaning is more general than "Epistasis, Genetic".
Below are MeSH descriptors whose meaning is more specific than "Epistasis, Genetic".
This graph shows the total number of publications written about "Epistasis, Genetic" by people in this website by year, and whether "Epistasis, Genetic" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1989 | 1 | 0 | 1 | | 1990 | 0 | 1 | 1 | | 1994 | 0 | 1 | 1 | | 1996 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 | | 1998 | 1 | 0 | 1 | | 2000 | 0 | 1 | 1 | | 2001 | 3 | 0 | 3 | | 2004 | 0 | 4 | 4 | | 2005 | 0 | 2 | 2 | | 2006 | 0 | 2 | 2 | | 2007 | 0 | 1 | 1 | | 2008 | 0 | 2 | 2 | | 2009 | 0 | 5 | 5 | | 2010 | 2 | 2 | 4 | | 2011 | 2 | 0 | 2 | | 2012 | 0 | 1 | 1 | | 2013 | 1 | 5 | 6 | | 2014 | 1 | 3 | 4 | | 2015 | 2 | 1 | 3 | | 2016 | 3 | 1 | 4 | | 2017 | 0 | 2 | 2 | | 2018 | 2 | 2 | 4 | | 2019 | 2 | 0 | 2 |
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Below are the most recent publications written about "Epistasis, Genetic" by people in Profiles.
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Poelwijk FJ, Socolich M, Ranganathan R. Learning the pattern of epistasis linking genotype and phenotype in a protein. Nat Commun. 2019 09 16; 10(1):4213.
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Kogan V, Millstein J, London SJ, Ober C, White SR, Naureckas ET, Gauderman WJ, Jackson DJ, Barraza-Villarreal A, Romieu I, Raby BA, Breton CV. Genetic-Epigenetic Interactions in Asthma Revealed by a Genome-Wide Gene-Centric Search. Hum Hered. 2018; 83(3):130-152.
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Boyle EA, Pritchard JK, Greenleaf WJ. High-resolution mapping of cancer cell networks using co-functional interactions. Mol Syst Biol. 2018 12 20; 14(12):e8594.
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Schumer M, Xu C, Powell DL, Durvasula A, Skov L, Holland C, Blazier JC, Sankararaman S, Andolfatto P, Rosenthal GG, Przeworski M. Natural selection interacts with recombination to shape the evolution of hybrid genomes. Science. 2018 May 11; 360(6389):656-660.
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Starr TN, Flynn JM, Mishra P, Bolon DNA, Thornton JW. Pervasive contingency and entrenchment in a billion years of Hsp90 evolution. Proc Natl Acad Sci U S A. 2018 04 24; 115(17):4453-4458.
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Argos M, Tong L, Roy S, Sabarinathan M, Ahmed A, Islam MT, Islam T, Rakibuz-Zaman M, Sarwar G, Shahriar H, Rahman M, Yunus M, Graziano JH, Jasmine F, Kibriya MG, Zhou X, Ahsan H, Pierce BL. Screening for gene-environment (G×E) interaction using omics data from exposed individuals: an application to gene-arsenic interaction. Mamm Genome. 2018 02; 29(1-2):101-111.
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Zuanetti DA, Müller P, Zhu Y, Yang S, Ji Y. Clustering distributions with the marginalized nested Dirichlet process. Biometrics. 2018 06; 74(2):584-594.
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Hochberg GKA, Thornton JW. Reconstructing Ancient Proteins to Understand the Causes of Structure and Function. Annu Rev Biophys. 2017 05 22; 46:247-269.
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Schwörer S, Becker F, Feller C, Baig AH, Köber U, Henze H, Kraus JM, Xin B, Lechel A, Lipka DB, Varghese CS, Schmidt M, Rohs R, Aebersold R, Medina KL, Kestler HA, Neri F, von Maltzahn J, Tümpel S, Rudolph KL. Epigenetic stress responses induce muscle stem-cell ageing by Hoxa9 developmental signals. Nature. 2016 12 15; 540(7633):428-432.
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Wang L, Heckman MG, Aasly JO, Annesi G, Bozi M, Chung SJ, Clarke C, Crosiers D, Eckstein G, Garraux G, Hadjigeorgiou GM, Hattori N, Jeon B, Kim YJ, Kubo M, Lesage S, Lin JJ, Lynch T, Lichtner P, Mellick GD, Mok V, Morrison KE, Quattrone A, Satake W, Silburn PA, Stefanis L, Stockton JD, Tan EK, Toda T, Brice A, Van Broeckhoven C, Uitti RJ, Wirdefeldt K, Wszolek Z, Xiromerisiou G, Maraganore DM, Gasser T, Krüger R, Farrer MJ, Ross OA, Sharma M. Evaluation of the interaction between LRRK2 and PARK16 loci in determining risk of Parkinson's disease: analysis of a large multicenter study. Neurobiol Aging. 2017 01; 49:217.e1-217.e4.
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