 Leukemia, Hairy Cell
"Leukemia, Hairy Cell" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A neoplastic disease of the lymphoreticular cells which is considered to be a rare type of chronic leukemia; it is characterized by an insidious onset, splenomegaly, anemia, granulocytopenia, thrombocytopenia, little or no lymphadenopathy, and the presence of "hairy" or "flagellated" cells in the blood and bone marrow.
| Descriptor ID |
D007943
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| MeSH Number(s) |
C04.557.337.415 C15.604.515.553 C20.683.515.517
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| Concept/Terms |
Leukemia, Hairy Cell- Leukemia, Hairy Cell
- Leukemic Reticuloendotheliosis
- Leukemic Reticuloendothelioses
- Reticuloendothelioses, Leukemic
- Reticuloendotheliosis, Leukemic
- Hairy Cell Leukemia
- Hairy Cell Leukemias
- Leukemias, Hairy Cell
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Below are MeSH descriptors whose meaning is more general than "Leukemia, Hairy Cell".
Below are MeSH descriptors whose meaning is more specific than "Leukemia, Hairy Cell".
This graph shows the total number of publications written about "Leukemia, Hairy Cell" by people in this website by year, and whether "Leukemia, Hairy Cell" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1980 | 4 | 0 | 4 | | 1981 | 5 | 0 | 5 | | 1982 | 3 | 0 | 3 | | 1983 | 7 | 0 | 7 | | 1984 | 9 | 0 | 9 | | 1985 | 8 | 0 | 8 | | 1986 | 9 | 1 | 10 | | 1987 | 13 | 0 | 13 | | 1988 | 12 | 0 | 12 | | 1989 | 5 | 0 | 5 | | 1990 | 4 | 0 | 4 | | 1991 | 3 | 0 | 3 | | 1992 | 7 | 0 | 7 | | 1993 | 2 | 0 | 2 | | 1994 | 4 | 0 | 4 | | 1995 | 2 | 0 | 2 | | 1997 | 0 | 1 | 1 | | 2000 | 2 | 0 | 2 | | 2002 | 1 | 0 | 1 | | 2008 | 2 | 0 | 2 | | 2011 | 2 | 0 | 2 | | 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Leukemia, Hairy Cell" by people in Profiles.
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Kang HB, Fan J, Lin R, Elf S, Ji Q, Zhao L, Jin L, Seo JH, Shan C, Arbiser JL, Cohen C, Brat D, Miziorko HM, Kim E, Abdel-Wahab O, Merghoub T, Fröhling S, Scholl C, Tamayo P, Barbie DA, Zhou L, Pollack BP, Fisher K, Kudchadkar RR, Lawson DH, Sica G, Rossi M, Lonial S, Khoury HJ, Khuri FR, Lee BH, Boggon TJ, He C, Kang S, Chen J. Metabolic Rewiring by Oncogenic BRAF V600E Links Ketogenesis Pathway to BRAF-MEK1 Signaling. Mol Cell. 2015 Aug 06; 59(3):345-358.
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Venkataraman G, Aguhar C, Kreitman RJ, Yuan CM, Stetler-Stevenson M. Characteristic CD103 and CD123 expression pattern defines hairy cell leukemia: usefulness of CD123 and CD103 in the diagnosis of mature B-cell lymphoproliferative disorders. Am J Clin Pathol. 2011 Oct; 136(4):625-30.
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Golomb HM. Fifty years of hairy cell leukemia treatments. Leuk Lymphoma. 2011 Jun; 52 Suppl 2:3-5.
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Rosen DS, Smith S, Gurbuxani S, Yamini B. Extranodal hairy cell leukemia presenting in the lumbar spine. J Neurosurg Spine. 2008 Oct; 9(4):374-6.
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Golomb HM. Hairy cell leukemia: treatment successes in the past 25 years. J Clin Oncol. 2008 Jun 01; 26(16):2607-9.
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Golde DW, Jakubowiak A, Caggiano J, Heaney ML. Cladribine underdosing in hairy-cell leukemia: a cause for apparent response failure. Leuk Lymphoma. 2002 Feb; 43(2):365-7.
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Flinn IW, Kopecky KJ, Foucar MK, Head D, Bennett JM, Hutchison R, Corbett W, Cassileth P, Habermann T, Golomb H, Rai K, Eisenhauer E, Appelbaum F, Cheson B, Grever MR. Long-term follow-up of remission duration, mortality, and second malignancies in hairy cell leukemia patients treated with pentostatin. Blood. 2000 Nov 01; 96(9):2981-6.
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Usha L, Bradlow B, Stock W, Platanias LC. CD5+ immunophenotype in the bone marrow but not in the peripheral blood in a patient with hairy cell leukemia. Acta Haematol. 2000; 103(4):210-3.
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Arber DA, Rappaport H, Weiss LM. Non-Hodgkin's lymphoproliferative disorders involving the spleen. Mod Pathol. 1997 Jan; 10(1):18-32.
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Rai KR, Davey F, Peterson B, Schiffer C, Silver RT, Ozer H, Golomb H, Bloomfield CD. Recombinant alpha-2b-interferon in therapy of previously untreated hairy cell leukemia: long-term follow-up results of study by Cancer and Leukemia Group B. Leukemia. 1995 Jul; 9(7):1116-20.
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