"Leukemia, Mast-Cell" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A form of systemic mastocytosis (MASTOCYTOSIS, SYSTEMIC) characterized by the presence of large numbers of tissue MAST CELLS in the peripheral blood without skin lesions. It is a high-grade LEUKEMIA disease with bone marrow smear of >20% MAST CELLS, multi-organ failure and a short survival.
Descriptor ID |
D007946
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MeSH Number(s) |
C04.557.337.440 C04.557.337.539.275.440 C04.557.450.565.465.750.500
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Concept/Terms |
Leukemia, Mast-Cell- Leukemia, Mast-Cell
- Leukemia, Mast Cell
- Leukemias, Mast-Cell
- Mast-Cell Leukemias
- Mast-Cell Leukemia
- Mast Cell Leukemia
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Below are MeSH descriptors whose meaning is more general than "Leukemia, Mast-Cell".
Below are MeSH descriptors whose meaning is more specific than "Leukemia, Mast-Cell".
This graph shows the total number of publications written about "Leukemia, Mast-Cell" by people in this website by year, and whether "Leukemia, Mast-Cell" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2001 | 0 | 1 | 1 |
2005 | 1 | 0 | 1 |
2008 | 0 | 1 | 1 |
2010 | 1 | 0 | 1 |
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Below are the most recent publications written about "Leukemia, Mast-Cell" by people in Profiles.
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Myelomastocytic leukemia versus mast cell leukemia versus systemic mastocytosis associated with acute myeloid leukemia: a diagnostic challenge. Am J Hematol. 2010 Aug; 85(8):600-6.
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The identification and characterisation of novel KIT transcripts in aggressive mast cell malignancies and normal CD34+ cells. Leuk Lymphoma. 2008 Aug; 49(8):1567-77.
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The tryptase positive compact round cell infiltrate of the bone marrow (TROCI-BM): a novel histopathological finding requiring the application of lineage specific markers. J Clin Pathol. 2006 Mar; 59(3):298-302.
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Activity of the tyrosine kinase inhibitor PKC412 in a patient with mast cell leukemia with the D816V KIT mutation. Blood. 2005 Oct 15; 106(8):2865-70.
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Diagnostic criteria and classification of mastocytosis: a consensus proposal. Leuk Res. 2001 Jul; 25(7):603-25.