 Leukocidins
"Leukocidins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Pore forming proteins originally discovered for toxic activity to LEUKOCYTES. They are EXOTOXINS produced by some pathogenic STAPHYLOCOCCUS and STREPTOCOCCUS that destroy leukocytes by lysis of the cytoplasmic granules and are partially responsible for the pathogenicity of the organisms.
| Descriptor ID |
D007956
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| MeSH Number(s) |
D12.776.543.695.750
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| Concept/Terms |
Leukocidins- Leukocidins
- Leukocidin Proteins
- Proteins, Leukocidin
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Below are MeSH descriptors whose meaning is more general than "Leukocidins".
Below are MeSH descriptors whose meaning is more specific than "Leukocidins".
This graph shows the total number of publications written about "Leukocidins" by people in this website by year, and whether "Leukocidins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Leukocidins" by people in Profiles.
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Li Z, Beesetty P, Gerges G, Kleinhenz M, Moore-Clingenpeel M, Yang C, Ahmed LB, Hensley J, Steele L, Chong AS, Montgomery CP. Impaired T-Lymphocyte Responses During Childhood Staphylococcus aureus Infection. J Infect Dis. 2022 01 05; 225(1):177-185.
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Eells SJ, David MZ, Taylor A, Ortiz N, Kumar N, Sieth J, Boyle-Vavra S, Daum RS, Miller LG. Persistent environmental contamination with USA300 methicillin-resistant Staphylococcus aureus and other pathogenic strain types in households with S. aureus skin infections. Infect Control Hosp Epidemiol. 2014 Nov; 35(11):1373-82.
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Fritz SA, Tiemann KM, Hogan PG, Epplin EK, Rodriguez M, Al-Zubeidi DN, Bubeck Wardenburg J, Hunstad DA. A serologic correlate of protective immunity against community-onset Staphylococcus aureus infection. Clin Infect Dis. 2013 Jun; 56(11):1554-61.
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Montgomery CP, Boyle-Vavra S, Roux A, Ebine K, Sonenshein AL, Daum RS. CodY deletion enhances in vivo virulence of community-associated methicillin-resistant Staphylococcus aureus clone USA300. Infect Immun. 2012 Jul; 80(7):2382-9.
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Gould IM, David MZ, Esposito S, Garau J, Lina G, Mazzei T, Peters G. New insights into meticillin-resistant Staphylococcus aureus (MRSA) pathogenesis, treatment and resistance. Int J Antimicrob Agents. 2012 Feb; 39(2):96-104.
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Anderson DM, Schmalzer KM, Sato H, Casey M, Terhune SS, Haas AL, Feix JB, Frank DW. Ubiquitin and ubiquitin-modified proteins activate the Pseudomonas aeruginosa T3SS cytotoxin, ExoU. Mol Microbiol. 2011 Dec; 82(6):1454-67.
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Kobayashi SD, Malachowa N, Whitney AR, Braughton KR, Gardner DJ, Long D, Bubeck Wardenburg J, Schneewind O, Otto M, Deleo FR. Comparative analysis of USA300 virulence determinants in a rabbit model of skin and soft tissue infection. J Infect Dis. 2011 Sep 15; 204(6):937-41.
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Montgomery CP, Boyle-Vavra S, Daum RS. Importance of the global regulators Agr and SaeRS in the pathogenesis of CA-MRSA USA300 infection. PLoS One. 2010 Dec 02; 5(12):e15177.
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Villaruz AE, Bubeck Wardenburg J, Khan BA, Whitney AR, Sturdevant DE, Gardner DJ, DeLeo FR, Otto M. A point mutation in the agr locus rather than expression of the Panton-Valentine leukocidin caused previously reported phenotypes in Staphylococcus aureus pneumonia and gene regulation. J Infect Dis. 2009 Sep 01; 200(5):724-34.
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Montgomery CP, Daum RS. Transcription of inflammatory genes in the lung after infection with community-associated methicillin-resistant Staphylococcus aureus: a role for panton-valentine leukocidin? Infect Immun. 2009 May; 77(5):2159-67.
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