"Leukocidins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Pore forming proteins originally discovered for toxic activity to LEUKOCYTES. They are EXOTOXINS produced by some pathogenic STAPHYLOCOCCUS and STREPTOCOCCUS that destroy leukocytes by lysis of the cytoplasmic granules and are partially responsible for the pathogenicity of the organisms.
| Descriptor ID |
D007956
|
| MeSH Number(s) |
D12.776.543.695.750
|
| Concept/Terms |
Leukocidins- Leukocidins
- Leukocidin Proteins
- Proteins, Leukocidin
|
Below are MeSH descriptors whose meaning is more general than "Leukocidins".
Below are MeSH descriptors whose meaning is more specific than "Leukocidins".
This graph shows the total number of publications written about "Leukocidins" by people in this website by year, and whether "Leukocidins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Leukocidins" by people in Profiles.
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Impaired T-Lymphocyte Responses During Childhood Staphylococcus aureus Infection. J Infect Dis. 2022 01 05; 225(1):177-185.
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Persistent environmental contamination with USA300 methicillin-resistant Staphylococcus aureus and other pathogenic strain types in households with S. aureus skin infections. Infect Control Hosp Epidemiol. 2014 Nov; 35(11):1373-82.
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A serologic correlate of protective immunity against community-onset Staphylococcus aureus infection. Clin Infect Dis. 2013 Jun; 56(11):1554-61.
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CodY deletion enhances in vivo virulence of community-associated methicillin-resistant Staphylococcus aureus clone USA300. Infect Immun. 2012 Jul; 80(7):2382-9.
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New insights into meticillin-resistant Staphylococcus aureus (MRSA) pathogenesis, treatment and resistance. Int J Antimicrob Agents. 2012 Feb; 39(2):96-104.
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Ubiquitin and ubiquitin-modified proteins activate the Pseudomonas aeruginosa T3SS cytotoxin, ExoU. Mol Microbiol. 2011 Dec; 82(6):1454-67.
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Comparative analysis of USA300 virulence determinants in a rabbit model of skin and soft tissue infection. J Infect Dis. 2011 Sep 15; 204(6):937-41.
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Importance of the global regulators Agr and SaeRS in the pathogenesis of CA-MRSA USA300 infection. PLoS One. 2010 Dec 02; 5(12):e15177.
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A point mutation in the agr locus rather than expression of the Panton-Valentine leukocidin caused previously reported phenotypes in Staphylococcus aureus pneumonia and gene regulation. J Infect Dis. 2009 Sep 01; 200(5):724-34.
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Transcription of inflammatory genes in the lung after infection with community-associated methicillin-resistant Staphylococcus aureus: a role for panton-valentine leukocidin? Infect Immun. 2009 May; 77(5):2159-67.