 Adenomatous Polyposis Coli
"Adenomatous Polyposis Coli" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood. The lifetime risk of colorectal cancer in these patients reaches 100 percent by age 60.
| Descriptor ID |
D011125
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| MeSH Number(s) |
C04.557.470.035.215.100 C04.588.274.476.411.307.089 C04.588.274.476.411.307.180.089 C04.700.100 C06.301.371.411.307.180.089 C06.405.249.411.307.180.089 C06.405.469.158.356.180.089 C06.405.469.491.307.180.089 C06.405.469.578.249 C16.320.700.100
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| Concept/Terms |
Adenomatous Polyposis Coli- Adenomatous Polyposis Coli
- Adenomatous Polyposis Colus
- Coli, Adenomatous Polyposis
- Colus, Adenomatous Polyposis
- Polyposis Coli, Adenomatous
- Polyposis Colus, Adenomatous
- Adenomatous Polyposis of the Colon
- Familial Adenomatous Polyposis
- Adenomatous Polyposes, Familial
- Adenomatous Polyposis, Familial
- Familial Adenomatous Polyposes
- Polyposes, Familial Adenomatous
- Polyposis, Familial Adenomatous
- Familial Adenomatous Polyposis Coli
- Polyposis Syndrome, Familial
- Familial Polyposis Syndrome
- Familial Polyposis Syndromes
- Familial Multiple Polyposi
- Familial Multiple Polyposus
- Multiple Polyposi, Familial
- Multiple Polyposus, Familial
- Polyposi, Familial Multiple
- Polyposus, Familial Multiple
- Familial Polyposis Coli
- Coli, Familial Polyposis
- Colus, Familial Polyposis
- Familial Polyposis Colus
- Polyposis Colus, Familial
- Familial Polyposis of the Colon
- Hereditary Polyposis Coli
- Coli, Hereditary Polyposis
- Colus, Hereditary Polyposis
- Hereditary Polyposis Colus
- Polyposis Coli, Hereditary
- Polyposis Colus, Hereditary
- Polyposis Coli, Familial
- Adenomatous Polyposis Coli, Familial
- Familial Adenomatous Polyposis of the Colon
Familial Intestinal Polyposis- Familial Intestinal Polyposis
- Familial Intestinal Polyposes
- Intestinal Polyposes, Familial
- Intestinal Polyposis, Familial
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Below are MeSH descriptors whose meaning is more general than "Adenomatous Polyposis Coli".
Below are MeSH descriptors whose meaning is more specific than "Adenomatous Polyposis Coli".
This graph shows the total number of publications written about "Adenomatous Polyposis Coli" by people in this website by year, and whether "Adenomatous Polyposis Coli" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1987 | 1 | 0 | 1 | | 1990 | 0 | 1 | 1 | | 1996 | 1 | 2 | 3 | | 1997 | 1 | 0 | 1 | | 1999 | 0 | 2 | 2 | | 2000 | 2 | 0 | 2 | | 2001 | 0 | 2 | 2 | | 2002 | 0 | 1 | 1 | | 2004 | 1 | 0 | 1 | | 2006 | 2 | 1 | 3 | | 2007 | 0 | 1 | 1 | | 2008 | 1 | 2 | 3 | | 2009 | 2 | 0 | 2 | | 2011 | 1 | 0 | 1 | | 2012 | 4 | 0 | 4 | | 2014 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 | | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Adenomatous Polyposis Coli" by people in Profiles.
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Osman A, Yan B, Li Y, Pavelko KD, Quandt J, Saadalla A, Singh MP, Kazemian M, Gounari F, Khazaie K. TCF-1 controls Treg cell functions that regulate inflammation, CD8+ T cell cytotoxicity and severity of colon cancer. Nat Immunol. 2021 09; 22(9):1152-1162.
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Heald B, Hampel H, Church J, Dudley B, Hall MJ, Mork ME, Singh A, Stoffel E, Stoll J, You YN, Yurgelun MB, Kupfer SS. Collaborative Group of the Americas on Inherited Gastrointestinal Cancer Position statement on multigene panel testing for patients with colorectal cancer and/or polyposis. Fam Cancer. 2020 07; 19(3):223-239.
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Crespo M, Vilar E, Tsai SY, Chang K, Amin S, Srinivasan T, Zhang T, Pipalia NH, Chen HJ, Witherspoon M, Gordillo M, Xiang JZ, Maxfield FR, Lipkin S, Evans T, Chen S. Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing. Nat Med. 2017 Jul; 23(7):878-884.
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Li J, Woods SL, Healey S, Beesley J, Chen X, Lee JS, Sivakumaran H, Wayte N, Nones K, Waterfall JJ, Pearson J, Patch AM, Senz J, Ferreira MA, Kaurah P, Mackenzie R, Heravi-Moussavi A, Hansford S, Lannagan TRM, Spurdle AB, Simpson PT, da Silva L, Lakhani SR, Clouston AD, Bettington M, Grimpen F, Busuttil RA, Di Costanzo N, Boussioutas A, Jeanjean M, Chong G, Fabre A, Olschwang S, Faulkner GJ, Bellos E, Coin L, Rioux K, Bathe OF, Wen X, Martin HC, Neklason DW, Davis SR, Walker RL, Calzone KA, Avital I, Heller T, Koh C, Pineda M, Rudloff U, Quezado M, Pichurin PN, Hulick PJ, Weissman SM, Newlin A, Rubinstein WS, Sampson JE, Hamman K, Goldgar D, Poplawski N, Phillips K, Schofield L, Armstrong J, Kiraly-Borri C, Suthers GK, Huntsman DG, Foulkes WD, Carneiro F, Lindor NM, Edwards SL, French JD, Waddell N, Meltzer PS, Worthley DL, Schrader KA, Chenevix-Trench G. Point Mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant. Am J Hum Genet. 2016 05 05; 98(5):830-842.
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Wang X, Song ZJ, He X, Zhang RQ, Zhang CF, Li F, Wang CZ, Yuan CS. Antitumor and immunomodulatory activity of genkwanin on colorectal cancer in the APC(Min/+) mice. Int Immunopharmacol. 2015 Dec; 29(2):701-707.
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Alikhan M, Koshy A, Hyjek E, Stenson K, Cohen RN, Yeo KT. Discrepant serum and urine ß-hCG results due to production of ß-hCG by a cribriform-morular variant of thyroid papillary carcinoma. Clin Chim Acta. 2015 Jan 01; 438:181-5.
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Listernick R, Nordli D, Tanz R, Stamos JK, Greene M, Liem R, Kiesau Y. An 11-year-old boy with seizures and fatigue. Pediatr Ann. 2012 Nov; 41(11):448-51.
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Roy HK, Khandekar JD. APC gene testing for familial adenomatosis polyposis. JAMA. 2012 Aug 01; 308(5):514-5.
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Khazaie K, Zadeh M, Khan MW, Bere P, Gounari F, Dennis K, Blatner NR, Owen JL, Klaenhammer TR, Mohamadzadeh M. Abating colon cancer polyposis by Lactobacillus acidophilus deficient in lipoteichoic acid. Proc Natl Acad Sci U S A. 2012 Jun 26; 109(26):10462-7.
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Pritchard CC, Smith C, Salipante SJ, Lee MK, Thornton AM, Nord AS, Gulden C, Kupfer SS, Swisher EM, Bennett RL, Novetsky AP, Jarvik GP, Olopade OI, Goodfellow PJ, King MC, Tait JF, Walsh T. ColoSeq provides comprehensive lynch and polyposis syndrome mutational analysis using massively parallel sequencing. J Mol Diagn. 2012 Jul; 14(4):357-66.
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