 Adenomatous Polyposis Coli
"Adenomatous Polyposis Coli" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood. The lifetime risk of colorectal cancer in these patients reaches 100 percent by age 60.
| Descriptor ID |
D011125
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| MeSH Number(s) |
C04.557.470.035.215.100 C04.588.274.476.411.307.089 C04.588.274.476.411.307.180.089 C04.700.100 C06.301.371.411.307.180.089 C06.405.249.411.307.180.089 C06.405.469.158.356.180.089 C06.405.469.491.307.180.089 C06.405.469.578.249 C16.320.700.100
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| Concept/Terms |
Adenomatous Polyposis Coli- Adenomatous Polyposis Coli
- Adenomatous Polyposis Colus
- Coli, Adenomatous Polyposis
- Colus, Adenomatous Polyposis
- Polyposis Coli, Adenomatous
- Polyposis Colus, Adenomatous
- Adenomatous Polyposis of the Colon
- Familial Adenomatous Polyposis
- Adenomatous Polyposes, Familial
- Adenomatous Polyposis, Familial
- Familial Adenomatous Polyposes
- Polyposes, Familial Adenomatous
- Polyposis, Familial Adenomatous
- Familial Adenomatous Polyposis Coli
- Polyposis Syndrome, Familial
- Familial Polyposis Syndrome
- Familial Polyposis Syndromes
- Familial Multiple Polyposi
- Familial Multiple Polyposus
- Multiple Polyposi, Familial
- Multiple Polyposus, Familial
- Polyposi, Familial Multiple
- Polyposus, Familial Multiple
- Familial Polyposis Coli
- Coli, Familial Polyposis
- Colus, Familial Polyposis
- Familial Polyposis Colus
- Polyposis Colus, Familial
- Familial Polyposis of the Colon
- Hereditary Polyposis Coli
- Coli, Hereditary Polyposis
- Colus, Hereditary Polyposis
- Hereditary Polyposis Colus
- Polyposis Coli, Hereditary
- Polyposis Colus, Hereditary
- Polyposis Coli, Familial
- Adenomatous Polyposis Coli, Familial
- Familial Adenomatous Polyposis of the Colon
Familial Intestinal Polyposis- Familial Intestinal Polyposis
- Familial Intestinal Polyposes
- Intestinal Polyposes, Familial
- Intestinal Polyposis, Familial
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Below are MeSH descriptors whose meaning is more general than "Adenomatous Polyposis Coli".
Below are MeSH descriptors whose meaning is more specific than "Adenomatous Polyposis Coli".
This graph shows the total number of publications written about "Adenomatous Polyposis Coli" by people in this website by year, and whether "Adenomatous Polyposis Coli" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 2 | 3 | | 1999 | 0 | 2 | 2 | | 2000 | 1 | 0 | 1 | | 2001 | 0 | 2 | 2 | | 2002 | 0 | 1 | 1 | | 2004 | 1 | 0 | 1 | | 2006 | 2 | 1 | 3 | | 2007 | 0 | 1 | 1 | | 2008 | 1 | 2 | 3 | | 2009 | 2 | 0 | 2 | | 2011 | 1 | 0 | 1 | | 2012 | 4 | 0 | 4 | | 2014 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2017 | 2 | 0 | 2 | | 2020 | 1 | 0 | 1 | | 2021 | 3 | 1 | 4 | | 2022 | 2 | 0 | 2 |
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Below are the most recent publications written about "Adenomatous Polyposis Coli" by people in Profiles.
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Kiran RP, Kochhar GS, Kariv R, Rex DK, Sugita A, Rubin DT, Navaneethan U, Hull TL, Ko HM, Liu X, Kachnic LA, Strong S, Iacucci M, Bemelman W, Fleshner P, Safyan RA, Kotze PG, D'Hoore A, Faiz O, Lo S, Ashburn JH, Spinelli A, Bernstein CN, Kane SV, Cross RK, Schairer J, McCormick JT, Farraye FA, Chang S, Scherl EJ, Schwartz DA, Bruining DH, Philpott J, Bentley-Hibbert S, Tarabar D, El-Hachem S, Sandborn WJ, Silverberg MS, Pardi DS, Church JM, Shen B. Management of pouch neoplasia: consensus guidelines from the International Ileal Pouch Consortium. Lancet Gastroenterol Hepatol. 2022 09; 7(9):871-893.
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Abbass MA, Lavryk OA, Hyman N, Liska D, Kalady MF, Church J. Nonspecific, Acute Pouchitis in Patients With Familial Adenomatous Polyposis: Less Common Than We Think. Dis Colon Rectum. 2022 06 01; 65(6):846-850.
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Shen B, Kochhar GS, Kariv R, Liu X, Navaneethan U, Rubin DT, Cross RK, Sugita A, D'Hoore A, Schairer J, Farraye FA, Kiran RP, Fleshner P, Rosh J, Shah SA, Chang S, Scherl E, Pardi DS, Schwartz DA, Kotze PG, Bruining DH, Kane SV, Philpott J, Abraham B, Segal J, Sedano R, Kayal M, Bentley-Hibbert S, Tarabar D, El-Hachem S, Sehgal P, McCormick JT, Picoraro JA, Silverberg MS, Bernstein CN, Sandborn WJ, Vermeire S. Diagnosis and classification of ileal pouch disorders: consensus guidelines from the International Ileal Pouch Consortium. Lancet Gastroenterol Hepatol. 2021 10; 6(10):826-849.
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Osman A, Yan B, Li Y, Pavelko KD, Quandt J, Saadalla A, Singh MP, Kazemian M, Gounari F, Khazaie K. TCF-1 controls Treg cell functions that regulate inflammation, CD8+ T cell cytotoxicity and severity of colon cancer. Nat Immunol. 2021 09; 22(9):1152-1162.
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Muller C, Yamada A, Ikegami S, Haider H, Komaki Y, Komaki F, Micic D, Sakuraba A. Risk of Colorectal Cancer in Serrated Polyposis Syndrome: A Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. 2022 03; 20(3):622-630.e7.
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Liu K, Kupfer SS, Jain R. A Case of Multiple Adenomatous Colon Polyps and Meningiomas. Gastroenterology. 2021 09; 161(3):811-813.
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Heald B, Hampel H, Church J, Dudley B, Hall MJ, Mork ME, Singh A, Stoffel E, Stoll J, You YN, Yurgelun MB, Kupfer SS. Collaborative Group of the Americas on Inherited Gastrointestinal Cancer Position statement on multigene panel testing for patients with colorectal cancer and/or polyposis. Fam Cancer. 2020 07; 19(3):223-239.
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Bendelsmith CR, Skrypek MM, Patel SR, Pond DA, Linabery AM, Bendel AE. Multiple pilomatrixomas in a survivor of WNT-activated medulloblastoma leading to the discovery of a germline APC mutation and the diagnosis of familial adenomatous polyposis. Pediatr Blood Cancer. 2018 Jan; 65(1).
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Crespo M, Vilar E, Tsai SY, Chang K, Amin S, Srinivasan T, Zhang T, Pipalia NH, Chen HJ, Witherspoon M, Gordillo M, Xiang JZ, Maxfield FR, Lipkin S, Evans T, Chen S. Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing. Nat Med. 2017 Jul; 23(7):878-884.
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Li J, Woods SL, Healey S, Beesley J, Chen X, Lee JS, Sivakumaran H, Wayte N, Nones K, Waterfall JJ, Pearson J, Patch AM, Senz J, Ferreira MA, Kaurah P, Mackenzie R, Heravi-Moussavi A, Hansford S, Lannagan TRM, Spurdle AB, Simpson PT, da Silva L, Lakhani SR, Clouston AD, Bettington M, Grimpen F, Busuttil RA, Di Costanzo N, Boussioutas A, Jeanjean M, Chong G, Fabre A, Olschwang S, Faulkner GJ, Bellos E, Coin L, Rioux K, Bathe OF, Wen X, Martin HC, Neklason DW, Davis SR, Walker RL, Calzone KA, Avital I, Heller T, Koh C, Pineda M, Rudloff U, Quezado M, Pichurin PN, Hulick PJ, Weissman SM, Newlin A, Rubinstein WS, Sampson JE, Hamman K, Goldgar D, Poplawski N, Phillips K, Schofield L, Armstrong J, Kiraly-Borri C, Suthers GK, Huntsman DG, Foulkes WD, Carneiro F, Lindor NM, Edwards SL, French JD, Waddell N, Meltzer PS, Worthley DL, Schrader KA, Chenevix-Trench G. Point Mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant. Am J Hum Genet. 2016 05 05; 98(5):830-842.
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