"Purine-Nucleoside Phosphorylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the reaction between a purine nucleoside and orthophosphate to form a free purine plus ribose-5-phosphate. EC 18.104.22.168.
- Purine-Nucleoside Phosphorylase
- Phosphorylase, Purine-Nucleoside
- Purine Nucleoside Phosphorylase
- Inosine Phosphorylase
- Phosphorylase, Inosine
- Purine Nucleoside Phosphorylases
- Nucleoside Phosphorylases, Purine
- Phosphorylases, Purine Nucleoside
Below are MeSH descriptors whose meaning is more general than "Purine-Nucleoside Phosphorylase".
Below are MeSH descriptors whose meaning is more specific than "Purine-Nucleoside Phosphorylase".
This graph shows the total number of publications written about "Purine-Nucleoside Phosphorylase" by people in this website by year, and whether "Purine-Nucleoside Phosphorylase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
|Year||Major Topic||Minor Topic||Total|
To return to the timeline, click here.
Below are the most recent publications written about "Purine-Nucleoside Phosphorylase" by people in Profiles.
MTAP immunohistochemistry is an accurate and reproducible surrogate for CDKN2A fluorescence in situ hybridization in diagnosis of malignant pleural mesothelioma. Mod Pathol. 2020 02; 33(2):245-254.
Genetic analysis of the pathogenic molecular sub-phenotype interferon-alpha identifies multiple novel loci involved in systemic lupus erythematosus. Genes Immun. 2015 Jan-Feb; 16(1):15-23.
A continuous kinetic assay for adenylation enzyme activity and inhibition. Anal Biochem. 2010 Sep 01; 404(1):56-63.
A phase II multicenter study of L-alanosine, a potent inhibitor of adenine biosynthesis, in patients with MTAP-deficient cancer. Invest New Drugs. 2009 Feb; 27(1):75-81.
Three new drugs for acute lymphoblastic leukemia: nelarabine, clofarabine, and forodesine. Semin Oncol. 2007 Dec; 34(6 Suppl 5):S13-20.
Diagnosis and treatment of Mycoplasma-contaminated cell cultures. Curr Protoc Microbiol. 2006 Jan; Appendix 3:Appendix 3B.
Identification of a 1.2 Kb cDNA fragment from a region on 9p21 commonly deleted in multiple tumor types. Cancer Genet Cytogenet. 2001 Sep; 129(2):93-101.
Diagnosis and treatment of mycoplasma-contaminated cell cultures. Curr Protoc Immunol. 2001 May; Appendix 3:Appendix 3E.
Codeletion of CDKN2 and MTAP genes in a subset of non-Hodgkin's lymphoma may be associated with histologic transformation from low-grade to diffuse large-cell lymphoma. Genes Chromosomes Cancer. 1998 May; 22(1):72-8.
Expression of methylthioadenosine phosphorylase cDNA in p16-, MTAP- malignant cells: restoration of methylthioadenosine phosphorylase-dependent salvage pathways and alterations of sensitivity to inhibitors of purine de novo synthesis. Mol Pharmacol. 1997 Nov; 52(5):903-11.