Purine-Nucleoside Phosphorylase
"Purine-Nucleoside Phosphorylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the reaction between a purine nucleoside and orthophosphate to form a free purine plus ribose-5-phosphate. EC 2.4.2.1.
| Descriptor ID |
D011683
|
| MeSH Number(s) |
D08.811.913.400.725.800
|
| Concept/Terms |
Purine-Nucleoside Phosphorylase- Purine-Nucleoside Phosphorylase
- Phosphorylase, Purine-Nucleoside
- Purine Nucleoside Phosphorylase
- Inosine Phosphorylase
- Phosphorylase, Inosine
- Purine Nucleoside Phosphorylases
- Nucleoside Phosphorylases, Purine
- Phosphorylases, Purine Nucleoside
|
Below are MeSH descriptors whose meaning is more general than "Purine-Nucleoside Phosphorylase".
Below are MeSH descriptors whose meaning is more specific than "Purine-Nucleoside Phosphorylase".
This graph shows the total number of publications written about "Purine-Nucleoside Phosphorylase" by people in this website by year, and whether "Purine-Nucleoside Phosphorylase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 2 | 2 |
| 1995 | 1 | 1 | 2 |
| 1996 | 0 | 2 | 2 |
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 2001 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Purine-Nucleoside Phosphorylase" by people in Profiles.
-
MTAP immunohistochemistry is an accurate and reproducible surrogate for CDKN2A fluorescence in situ hybridization in diagnosis of malignant pleural mesothelioma. Mod Pathol. 2020 02; 33(2):245-254.
-
Genetic analysis of the pathogenic molecular sub-phenotype interferon-alpha identifies multiple novel loci involved in systemic lupus erythematosus. Genes Immun. 2015 Jan-Feb; 16(1):15-23.
-
A continuous kinetic assay for adenylation enzyme activity and inhibition. Anal Biochem. 2010 Sep 01; 404(1):56-63.
-
A phase II multicenter study of L-alanosine, a potent inhibitor of adenine biosynthesis, in patients with MTAP-deficient cancer. Invest New Drugs. 2009 Feb; 27(1):75-81.
-
Three new drugs for acute lymphoblastic leukemia: nelarabine, clofarabine, and forodesine. Semin Oncol. 2007 Dec; 34(6 Suppl 5):S13-20.
-
Diagnosis and treatment of Mycoplasma-contaminated cell cultures. Curr Protoc Microbiol. 2006 Jan; Appendix 3:Appendix 3B.
-
Identification of a 1.2 Kb cDNA fragment from a region on 9p21 commonly deleted in multiple tumor types. Cancer Genet Cytogenet. 2001 Sep; 129(2):93-101.
-
Diagnosis and treatment of mycoplasma-contaminated cell cultures. Curr Protoc Immunol. 2001 May; Appendix 3:Appendix 3E.
-
Codeletion of CDKN2 and MTAP genes in a subset of non-Hodgkin's lymphoma may be associated with histologic transformation from low-grade to diffuse large-cell lymphoma. Genes Chromosomes Cancer. 1998 May; 22(1):72-8.
-
Expression of methylthioadenosine phosphorylase cDNA in p16-, MTAP- malignant cells: restoration of methylthioadenosine phosphorylase-dependent salvage pathways and alterations of sensitivity to inhibitors of purine de novo synthesis. Mol Pharmacol. 1997 Nov; 52(5):903-11.