Nicotinamide Phosphoribosyltransferase
"Nicotinamide Phosphoribosyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the formation of nicotinamide mononucleotide (NMN) from nicotinamide and 5-phosphoribosyl-1-pyrophosphate, the rate-limiting step in the biosynthesis of the NAD coenzyme. It is also known as a growth factor for early B-LYMPHOCYTES, or an ADIPOKINE with insulin-mimetic effects (visfatin).
| Descriptor ID |
D054409
|
| MeSH Number(s) |
D08.811.913.400.725.575
|
| Concept/Terms |
Nicotinamide Phosphoribosyltransferase- Nicotinamide Phosphoribosyltransferase
- Phosphoribosyltransferase, Nicotinamide
- NAMPT Protein
- Pre-B-Cell Colony-Enhancing Factor
- Colony-Enhancing Factor, Pre-B-Cell
- Pre B Cell Colony Enhancing Factor
- Visfatin
- NAmPRTase
- NMN Pyrophosphorylase
|
Below are MeSH descriptors whose meaning is more general than "Nicotinamide Phosphoribosyltransferase".
Below are MeSH descriptors whose meaning is more specific than "Nicotinamide Phosphoribosyltransferase".
This graph shows the total number of publications written about "Nicotinamide Phosphoribosyltransferase" by people in this website by year, and whether "Nicotinamide Phosphoribosyltransferase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 3 | 3 |
| 2008 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Nicotinamide Phosphoribosyltransferase" by people in Profiles.
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Immunometabolic Status of COVID-19 Cancer Patients. Physiol Rev. 2020 10 01; 100(4):1839-1850.
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The NAMPT promoter is regulated by mechanical stress, signal transducer and activator of transcription 5, and acute respiratory distress syndrome-associated genetic variants. Am J Respir Cell Mol Biol. 2014 Nov; 51(5):660-7.
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Nampt secreted from cardiomyocytes promotes development of cardiac hypertrophy and adverse ventricular remodeling. Am J Physiol Heart Circ Physiol. 2013 Feb 01; 304(3):H415-26.
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Plasma and myocardial visfatin expression changes are associated with therapeutic hypothermia protection during murine hemorrhagic shock/resuscitation. Resuscitation. 2010 Jun; 81(6):742-8.
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Dietary and physical activity patterns in children with obstructive sleep apnea. J Pediatr. 2010 May; 156(5):724-30, 730.e1-730.e3.
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Essential role of pre-B-cell colony enhancing factor in ventilator-induced lung injury. Am J Respir Crit Care Med. 2008 Sep 15; 178(6):605-17.
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Interactions between PBEF and oxidative stress proteins--a potential new mechanism underlying PBEF in the pathogenesis of acute lung injury. FEBS Lett. 2008 Jun 11; 582(13):1802-8.
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Pre-B-cell-colony-enhancing factor is critically involved in thrombin-induced lung endothelial cell barrier dysregulation. Microvasc Res. 2005 Nov; 70(3):142-51.
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Pre-B-cell colony-enhancing factor regulates vascular smooth muscle maturation through a NAD+-dependent mechanism: recognition of a new mechanism for cell diversity and redox regulation of vascular tone and remodeling. Circ Res. 2005 Jul 08; 97(1):4-7.
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Molecular cloning and characterization of canine pre-B-cell colony-enhancing factor. Biochem Genet. 2005 Apr; 43(3-4):127-41.