"Iloprost" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An eicosanoid, derived from the cyclooxygenase pathway of arachidonic acid metabolism. It is a stable and synthetic analog of EPOPROSTENOL, but with a longer half-life than the parent compound. Its actions are similar to prostacyclin. Iloprost produces vasodilation and inhibits platelet aggregation.
| Descriptor ID |
D016285
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| MeSH Number(s) |
D10.251.355.255.550.775.125 D23.469.050.175.725.775.125 D23.469.700.275
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Iloprost".
Below are MeSH descriptors whose meaning is more specific than "Iloprost".
This graph shows the total number of publications written about "Iloprost" by people in this website by year, and whether "Iloprost" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 1 | 2 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Iloprost" by people in Profiles.
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Regulation of myofibroblast differentiation and bleomycin-induced pulmonary fibrosis by adrenomedullin. Am J Physiol Lung Cell Mol Physiol. 2013 Jun 01; 304(11):L757-64.
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VE-cadherin trans-interactions modulate Rac activation and enhancement of lung endothelial barrier by iloprost. J Cell Physiol. 2012 Oct; 227(10):3405-16.
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Iloprost improves endothelial barrier function in lipopolysaccharide-induced lung injury. Eur Respir J. 2013 Jan; 41(1):165-76.
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Occurrence and multiple recurrence of severe vasospasm of the upper extremity following thorascopic sympathectomy for hyperhidrosis. Eur J Vasc Endovasc Surg. 2011 Feb; 41(2):264-6.
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Lung endothelial barrier protection by iloprost in the 2-hit models of ventilator-induced lung injury (VILI) involves inhibition of Rho signaling. Transl Res. 2010 Jan; 155(1):44-54.
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Rap1 mediates protective effects of iloprost against ventilator-induced lung injury. J Appl Physiol (1985). 2009 Dec; 107(6):1900-10.
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An evidence-based approach to the management of pulmonary arterial hypertension. Curr Opin Cardiol. 2006 Jul; 21(4):385-92.
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Prostacyclin therapy for pulmonary arterial hypertension: new directions. Semin Respir Crit Care Med. 2005 Aug; 26(4):394-401.
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EP1 receptor blockade attenuates both spontaneous tone and PGE2-elicited contraction in guinea pig trachealis. Am J Physiol. 1997 Sep; 273(3 Pt 1):L626-33.
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Iloprost reduces procoagulant activity in the extracorporeal circuit. J Surg Res. 1993 Oct; 55(4):433-40.