"Myofibroblasts" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Spindle-shaped cells with characteristic CONTRACTILE PROTEINS and structures that contribute to the WOUND HEALING process. They occur in GRANULATION TISSUE and also in pathological processes such as FIBROSIS.
| Descriptor ID |
D058628
|
| MeSH Number(s) |
A11.329.228.975 A11.620.520.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Myofibroblasts".
Below are MeSH descriptors whose meaning is more specific than "Myofibroblasts".
This graph shows the total number of publications written about "Myofibroblasts" by people in this website by year, and whether "Myofibroblasts" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 3 | 1 | 4 |
| 2013 | 2 | 0 | 2 |
| 2014 | 1 | 1 | 2 |
| 2015 | 2 | 2 | 4 |
| 2016 | 4 | 1 | 5 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 1 | 2 |
| 2019 | 3 | 4 | 7 |
| 2020 | 2 | 0 | 2 |
| 2021 | 2 | 0 | 2 |
| 2023 | 2 | 1 | 3 |
| 2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "Myofibroblasts" by people in Profiles.
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Blocking antibodies against integrin-a3, -aM, and -aMß2 de-differentiate myofibroblasts, and improve lung fibrosis and kidney fibrosis. Sci Rep. 2024 09 16; 14(1):21623.
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IL11-mediated stromal cell activation may not be the master regulator of pro-fibrotic signaling downstream of TGFß. Front Immunol. 2024; 15:1293883.
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Anoctamin-1 is induced by TGF-ß and contributes to lung myofibroblast differentiation. Am J Physiol Lung Cell Mol Physiol. 2024 01 01; 326(1):L111-L123.
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Central lung gene expression associates with myofibroblast features in idiopathic pulmonary fibrosis. BMJ Open Respir Res. 2023 02; 10(1).
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CD26-negative and CD26-positive tissue-resident fibroblasts contribute to functionally distinct CAF subpopulations in breast cancer. Nat Commun. 2023 01 12; 14(1):183.
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Engineered microenvironment for the study of myofibroblast mechanobiology. Wound Repair Regen. 2021 07; 29(4):588-596.
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The role of metabolic reprogramming and de novo amino acid synthesis in collagen protein production by myofibroblasts: implications for organ fibrosis and cancer. Amino Acids. 2021 Dec; 53(12):1851-1862.
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Established fibrous peritoneal metastasis in an immunocompetent mouse model similar to clinical immune microenvironment of gastric cancer. BMC Cancer. 2020 Oct 20; 20(1):1014.
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Epigenetic Metabolic Reprogramming of Right Ventricular Fibroblasts in Pulmonary Arterial Hypertension: A Pyruvate Dehydrogenase Kinase-Dependent Shift in Mitochondrial Metabolism Promotes Right Ventricular Fibrosis. Circ Res. 2020 06 05; 126(12):1723-1745.
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Increased Glutaminolysis Marks Active Scarring in Nonalcoholic Steatohepatitis Progression. Cell Mol Gastroenterol Hepatol. 2020; 10(1):1-21.