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Caner Saygin

TitleAssistant Professor
InstitutionUniversity of Chicago
DepartmentMedicine-Hematology and Oncology
AddressChicago IL 60637
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    Saygin Lab studies leukemia biology by using in vitro and in vivo models of acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL), as well as human samples obtained from patients with leukemia. We are particularly interested in drivers of CHIP (clonal hematopoiesis of indeterminate potential) progression to leukemias of myeloid vs lymphoid lineage in de novo and therapy-related leukemogenesis. Our translational research lab aims to identify mechanisms driving these fatal diseases and leverage them for new experimental therapeutics. Our drug development efforts focusing on high-risk subsets of AML and ALL have led to “home-grown” phase I/II investigator-initiated clinical trials.
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Madero-Marroquin R, Dworkin E, Weiner H, Saygin C, Nawas MT, Drazer MW, DuVall AS, Kosuri S, Thirman MJ, Odenike O, Stock W, Larson RA, Patel AA. Treatment outcomes of venetoclax-combination regimens for relapsed/refractory myeloid malignancies after anti-CD47-directed therapy. Leuk Lymphoma. 2024 Mar 05; 1-4. PMID: 38441062.
      Citations:    Fields:    
    2. Johnston H, Youshanlouei HR, Osei C, Patel AA, DuVall A, Wang P, Wanjari P, Segal J, Venkataraman G, Cheng JX, Gurbuxani S, Lager A, Fitzpatrick C, Thirman M, Nawas M, Liu H, Drazer M, Odenike O, Larson R, Stock W, Saygin C. Socioeconomic determinants of the biology and outcomes of acute lymphoblastic leukemia in adults. Blood Adv. 2024 01 09; 8(1):164-171. PMID: 38039510; PMCID: PMC10787242.
      Citations:    Fields:    Translation:Humans
    3. Parriott G, Hegermiller E, Morman RE, Frank C, Saygin C, Stock W, Bartom ET, Kee BL. Loss of thymocyte competition underlies the tumor suppressive functions of the E2a transcription factor in T-ALL. Leukemia. 2024 Mar; 38(3):491-501. PMID: 38155245.
      Citations:    Fields:    Translation:AnimalsCells
    4. Saygin C, Zhang P, Stauber J, Aldoss I, Sperling AS, Weeks LD, Luskin MR, Knepper TC, Wanjari P, Wang P, Lager AM, Fitzpatrick C, Segal JP, Gharghabi M, Gurbuxani S, Venkataraman G, Cheng JX, Eisfelder BJ, Bohorquez O, Patel AA, Umesh Nagalakshmi S, Jayaram S, Odenike OM, Larson RA, Godley LA, Arber DA, Gibson CJ, Munshi NC, Marcucci G, Ebert BL, Greally JM, Steidl U, Lapalombella R, Shah BD, Stock W. Acute lymphoblastic leukemia with myeloid mutations is a high-risk disease associated with clonal hematopoiesis. Blood Cancer Discov. 2023 Dec 27. PMID: 38150184.
      Citations:    Fields:    
    5. Madero-Marroquin R, DuVall AS, Saygin C, Wang P, Gurbuxani S, Larson RA, Stock W, Patel AA. Durable responses in acute lymphoblastic leukaemia with the use of FLT3 and IDH inhibitors. Br J Haematol. 2024 Apr; 204(4):1238-1242. PMID: 38073116.
      Citations:    Fields:    
    6. Kraft IL, Basdag H, Koppayi A, Rodgers CV, Saygin C, Haribabu Y, Wanjari P, Niu N, Das S, de Jong JLO, Segal J, Godley LA. Sequential tumor molecular profiling identifies likely germline variants. Genet Med. 2024 Mar; 26(3):101037. PMID: 38054407.
      Citations:    Fields:    Translation:HumansCells
    7. Alaggio R, Amador C, Anagnostopoulos I, Attygalle AD, de Oliveira Araujo IB, Berti E, Bhagat G, Borges AM, Boyer D, Calaminici M, Chadburn A, Chan JKC, Cheuk W, Chng WJ, Choi JK, Chuang SS, Coupland SE, Czader M, Dave SS, de Jong D, Di Napoli A, Du MQ, Elenitoba-Johnson KS, Ferry J, Geyer J, Gratzinger D, Guitart J, Gujral S, Harris M, Harrison CJ, Hartmann S, Hochhaus A, Jansen PM, Karube K, Kempf W, Khoury J, Kimura H, Klapper W, Kovach AE, Kumar S, Lazar AJ, Lazzi S, Leoncini L, Leung N, Leventaki V, Li XQ, Lim MS, Liu WP, Louissaint A, Marcogliese A, Medeiros LJ, Michal M, Miranda RN, Mitteldorf C, Montes-Moreno S, Morice W, Nardi V, Naresh KN, Natkunam Y, Ng SB, Oschlies I, Ott G, Parrens M, Pulitzer M, Rajkumar SV, Rawstron AC, Rech K, Rosenwald A, Said J, Sarkozy C, Sayed S, Saygin C, Schuh A, Sewell W, Siebert R, Sohani AR, Suzuki R, Tooze R, Traverse-Glehen A, Vega F, Vergier B, Wechalekar AD, Wood B, Xerri L, Xiao W, International Agency for Research on Cancer/World Health Organization. Correction: "The 5th edition of The World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms" Leukemia. 2022 Jul;36(7):1720-1748. Leukemia. 2023 Sep; 37(9):1944-1951. PMID: 37468552; PMCID: PMC10457187.
      Citations:    Fields:    
    8. Saygin C, Giordano G, Shimamoto K, Eisfelder B, Thomas-Toth A, Venkataraman G, Ananthanarayanan V, Vincent TL, DuVall A, Patel AA, Chen Y, Tan F, Anthony SP, Chen Y, Shen Y, Odenike O, Teachey DT, Kee BL, LaBelle J, Stock W. Dual Targeting of Apoptotic and Signaling Pathways in T-Lineage Acute Lymphoblastic Leukemia. Clin Cancer Res. 2023 08 15; 29(16):3151-3161. PMID: 37363966; PMCID: PMC10425730.
      Citations: 1     Fields:    Translation:HumansCells
    9. Saygin C. From cell surface to nucleus: CCRL2 regulates response to hypomethylating agents in myelodysplastic syndromes. Haematologica. 2023 Jul 01; 108(7):1729-1730. PMID: 36794505; PMCID: PMC10316268.
      Citations:    Fields:    Translation:HumansCells
    10. Osman AEG, Mencia-Trinchant N, Saygin C, Moma L, Kim A, Housman G, Pozsgai M, Sinha E, Chandra P, Hassane DC, Sboner A, Sangani K, DiNardi N, Johnson C, Wallace SS, Jabri B, Luu H, Guzman ML, Desai P, Godley LA. Paired bone marrow and peripheral blood samples demonstrate lack of widespread dissemination of some CH clones. Blood Adv. 2023 05 09; 7(9):1910-1914. PMID: 36453641; PMCID: PMC10172868.
      Citations: 2     Fields:    Translation:HumansCells
    11. Parriott G, Hegermiller E, Morman RE, Frank C, Saygin C, Stock W, Bartom ET, Kee BL. Loss of thymocyte competition underlies the tumor suppressive functions of the E2a transcription factor in T lymphocyte acute lymphoblastic leukemia. bioRxiv. 2023 Apr 25. PMID: 37163059; PMCID: PMC10168235.
      Citations:    
    12. Saygin C, Roloff G, Hahn CN, Chhetri R, Gill S, Elmariah H, Talati C, Nunley E, Gao G, Kim A, Bishop M, Kosuri S, Das S, Singhal D, Venugopal P, Homan CC, Brown A, Scott HS, Hiwase D, Godley LA. Allogeneic hematopoietic stem cell transplant outcomes in adults with inherited myeloid malignancies. Blood Adv. 2023 02 28; 7(4):549-554. PMID: 36001442; PMCID: PMC9979761.
      Citations: 11     Fields:    Translation:Humans
    13. Saygin C, Cannova J, Stock W, Muffly L. Measurable residual disease in acute lymphoblastic leukemia: methods and clinical context in adult patients. Haematologica. 2022 Dec 01; 107(12):2783-2793. PMID: 36453516.
      Citations: 5     Fields:    Translation:Humans
    14. Alaggio R, Amador C, Anagnostopoulos I, Attygalle AD, Araujo IBO, Berti E, Bhagat G, Borges AM, Boyer D, Calaminici M, Chadburn A, Chan JKC, Cheuk W, Chng WJ, Choi JK, Chuang SS, Coupland SE, Czader M, Dave SS, de Jong D, Du MQ, Elenitoba-Johnson KS, Ferry J, Geyer J, Gratzinger D, Guitart J, Gujral S, Harris M, Harrison CJ, Hartmann S, Hochhaus A, Jansen PM, Karube K, Kempf W, Khoury J, Kimura H, Klapper W, Kovach AE, Kumar S, Lazar AJ, Lazzi S, Leoncini L, Leung N, Leventaki V, Li XQ, Lim MS, Liu WP, Louissaint A, Marcogliese A, Medeiros LJ, Michal M, Miranda RN, Mitteldorf C, Montes-Moreno S, Morice W, Nardi V, Naresh KN, Natkunam Y, Ng SB, Oschlies I, Ott G, Parrens M, Pulitzer M, Rajkumar SV, Rawstron AC, Rech K, Rosenwald A, Said J, Sarkozy C, Sayed S, Saygin C, Schuh A, Sewell W, Siebert R, Sohani AR, Tooze R, Traverse-Glehen A, Vega F, Vergier B, Wechalekar AD, Wood B, Xerri L, Xiao W. The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms. Leukemia. 2022 07; 36(7):1720-1748. PMID: 35732829; PMCID: PMC9214472.
      Citations: 519     Fields:    Translation:Humans
    15. Siddiqui F, Perez Silos V, Karube K, Yasin Goksu S, Nandakumar S, Saygin C, Onajin O, Prabu SS, Gurbuxani S, Arber DA, Tjota M, Segal J, Smith SM, Murga-Zamalloa CA, Venkataraman G. B-cell lymphoma-2 downregulation is a useful feature supporting a neoplastic phenotype in mature T-cell lymphomas. Hum Pathol. 2022 07; 125:48-58. PMID: 35452696.
      Citations: 2     Fields:    Translation:HumansCells
    16. Saygin C, Hu E, Zhang P, Sher S, Lozanski A, Doong TJ, Nicolet D, Orwick S, Labanowska J, Skinner JN, Cempre C, Kauffman T, Goettl VM, Heerema NA, Abruzzo L, Miller C, Lapalombella R, Behbehani G, Mims AS, Larkin K, Grieselhuber N, Walker A, Bhatnagar B, Bloomfield CD, Byrd JC, Lozanski G, Blachly JS. Correction: Genomic analysis of cellular hierarchy in acute myeloid leukemia using ultrasensitive LC-FACSeq. Leukemia. 2021 Dec; 35(12):3627. PMID: 34480107; PMCID: PMC8632666.
      Citations:    Fields:    
    17. Schaefer A, Huang Y, Kittai A, Maakaron JE, Saygin C, Brammer J, Penza S, Saad A, Jaglowski SM, William BM. Cytopenias After CD19 Chimeric Antigen Receptor T-Cells (CAR-T) Therapy for Diffuse Large B-Cell Lymphomas or Transformed Follicular Lymphoma: A Single Institution Experience. Cancer Manag Res. 2021; 13:8901-8906. PMID: 34876852; PMCID: PMC8643129.
      Citations: 7     
    18. Saygin C, Godley LA. Genetics of Myelodysplastic Syndromes. Cancers (Basel). 2021 Jul 06; 13(14). PMID: 34298596; PMCID: PMC8304604.
      Citations: 5     
    19. Saygin C, Hu E, Zhang P, Sher S, Lozanski A, Doong TJ, Nicolet D, Orwick S, Labanowska J, Skinner JN, Cempre C, Kauffman T, Goettl VM, Heerema NA, Abruzzo L, Miller C, Lapalombella R, Behbehani G, Mims AS, Larkin K, Grieselhuber N, Walker A, Bhatnagar B, Bloomfield CD, Byrd JC, Lozanski G, Blachly JS. Genomic analysis of cellular hierarchy in acute myeloid leukemia using ultrasensitive LC-FACSeq. Leukemia. 2021 12; 35(12):3406-3420. PMID: 34021247; PMCID: PMC8606012.
      Citations: 3     Fields:    Translation:HumansCells
    20. Patel AA, Cahill K, Saygin C, Odenike O. Cedazuridine/decitabine: from preclinical to clinical development in myeloid malignancies. Blood Adv. 2021 04 27; 5(8):2264-2271. PMID: 33904891; PMCID: PMC8095139.
      Citations: 10     Fields:    Translation:Humans
    21. Crean-Tate KK, Braley C, Dey G, Esakov E, Saygin C, Trestan A, Silver DJ, Turaga SM, Connor EV, DeBernardo R, Michener CM, Rose PG, Lathia J, Reizes O. Pretreatment with LCK inhibitors chemosensitizes cisplatin-resistant endometrioid ovarian tumors. J Ovarian Res. 2021 Apr 22; 14(1):55. PMID: 33888137; PMCID: PMC8063392.
      Citations: 3     Fields:    Translation:HumansAnimals
    22. Ozga M, Blachly J, Eisfeld AK, Grieselhuber N, Larkin K, Walker A, Bhatnagar B, Behbehani G, Long M, Haque T, Vasu S, Zhao W, Jones D, Byrd JC, Mims AS, Saygin C. Type of prior genotoxic insult determines the genomic characteristics of therapy-related myeloid neoplasms. Am J Hematol. 2021 07 01; 96(7):E223-E225. PMID: 33761147.
      Citations: 2     Fields:    Translation:Humans
    23. Eisfelder BJ, Saygin C, Wynne J, Colton MW, Fischietti M, Beauchamp EM, Cheng JX, Odenike O, Roboz G, Alachkar H, Stock W. OTS167 blocks FLT3 translation and synergizes with FLT3 inhibitors in FLT3 mutant acute myeloid leukemia. Blood Cancer J. 2021 03 03; 11(3):48. PMID: 33658483; PMCID: PMC7930094.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    24. Saygin C, Carraway HE. Current and emerging strategies for management of myelodysplastic syndromes. Blood Rev. 2021 07; 48:100791. PMID: 33423844.
      Citations: 18     Fields:    Translation:Humans
    25. Carraway HE, Saygin C. Therapy for lower-risk MDS. Hematology Am Soc Hematol Educ Program. 2020 12 04; 2020(1):426-433. PMID: 33275714; PMCID: PMC7727572.
      Citations: 13     Fields:    Translation:Humans
    26. Saygin C, Larkin K, Blachly JS, Orwick S, Ngankeu A, Gregory CT, Phelps MA, Mani S, Walker A, Garzon R, Vasu S, Walsh KJ, Bhatnagar B, Klisovic RB, Grever MR, Marcucci G, Byrd JC, Blum W, Mims AS. A phase I study of lenalidomide plus chemotherapy with idarubicin and cytarabine in patients with relapsed or refractory acute myeloid leukemia and high-risk myelodysplastic syndrome. Am J Hematol. 2020 12; 95(12):1457-1465. PMID: 32777116; PMCID: PMC7821016.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    27. Hu EY, Blachly JS, Saygin C, Ozer HG, Workman SE, Lozanski A, Doong TJ, Chiang CL, Bhat S, Rogers KA, Woyach JA, Coombes KR, Jones D, Muthusamy N, Lozanski G, Byrd JC. LC-FACSeq is a method for detecting rare clones in leukemia. JCI Insight. 2020 06 18; 5(12). PMID: 32554930; PMCID: PMC7406301.
      Citations: 3     Fields:    Translation:HumansCells
    28. Saygin C, Grieselhuber N, Blachly J, Byrd JC, Vasu S, Larkin K, Behbehani G, Long M, Walker A, Bhatnagar B, Mims A. Outcomes of the cyclophosphamide, vincristine, prednisone (CVP) +/- rituximab (R-CVP) regimen in older patients with newly diagnosed Ph- acute lymphoblastic leukemia. Leuk Res. 2020 02; 89:106297. PMID: 31935625.
      Citations: 2     Fields:    Translation:Humans
    29. Saygin C, Kishtagari A, Cassaday RD, Reizine N, Yurkiewicz I, Liedtke M, Stock W, Larson RA, Levine RL, Tallman MS, Park JH, Kerr C, Przychodzen B, Sekeres MA, Kalaycio ME, Carraway HE, Hamilton BK, Sobecks R, Gerds A, Mukherjee S, Nazha A, Maciejewski JP, Advani AS. Therapy-related acute lymphoblastic leukemia is a distinct entity with adverse genetic features and clinical outcomes. Blood Adv. 2019 12 23; 3(24):4228-4237. PMID: 31869410; PMCID: PMC6929388.
      Citations: 14     Fields:    Translation:Humans
    30. Connor EV, Saygin C, Braley C, Wiechert AC, Karunanithi S, Crean-Tate K, Abdul-Karim FW, Michener CM, Rose PG, Lathia JD, Reizes O. Thy-1 predicts poor prognosis and is associated with self-renewal in ovarian cancer. J Ovarian Res. 2019 Nov 17; 12(1):112. PMID: 31735168; PMCID: PMC6858973.
      Citations: 11     Fields:    Translation:HumansCells
    31. Saygin C, Matei D, Majeti R, Reizes O, Lathia JD. Targeting Cancer Stemness in the Clinic: From Hype to Hope. Cell Stem Cell. 2019 01 03; 24(1):25-40. PMID: 30595497.
      Citations: 229     Fields:    Translation:HumansAnimalsCells
    32. Schmidt S, Shay LA, Saygin C, Wan HD, Schulz K, Clark RA, Shireman PK. Improving pilot project application and review processes: A novel application of lean six sigma in translational science. J Clin Transl Sci. 2018 Jun; 2(3):135-138. PMID: 30370065; PMCID: PMC6199542.
      Citations: 5     
    33. Thiagarajan PS, Sinyuk M, Turaga SM, Mulkearns-Hubert EE, Hale JS, Rao V, Demelash A, Saygin C, China A, Alban TJ, Hitomi M, Torre-Healy LA, Alvarado AG, Jarrar A, Wiechert A, Adorno-Cruz V, Fox PL, Calhoun BC, Guan JL, Liu H, Reizes O, Lathia JD. Cx26 drives self-renewal in triple-negative breast cancer via interaction with NANOG and focal adhesion kinase. Nat Commun. 2018 02 08; 9(1):578. PMID: 29422613; PMCID: PMC5805730.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    34. Saygin C, Hirsch C, Przychodzen B, Sekeres MA, Hamilton BK, Kalaycio M, Carraway HE, Gerds AT, Mukherjee S, Nazha A, Sobecks R, Goebel C, Abounader D, Maciejewski JP, Advani AS. Mutations in DNMT3A, U2AF1, and EZH2 identify intermediate-risk acute myeloid leukemia patients with poor outcome after CR1. Blood Cancer J. 2018 01 10; 8(1):4. PMID: 29321554; PMCID: PMC5802549.
      Citations: 23     Fields:    Translation:HumansCTClinical Trials
    35. Malek E, Saygin C, Ye R, Covut F, Kim BG, Welge J, Meropol NJ, De Lima M, Driscoll JJ. Predicting Successful Phase Advancement and Regulatory Approval in Multiple Myeloma From Phase I Overall Response Rates. JCO Clin Cancer Inform. 2017 11; 1:1-14. PMID: 30657399.
      Citations:    Fields:    Translation:Humans
    36. Dashzeveg NK, Taftaf R, Ramos EK, Torre-Healy L, Chumakova A, Silver DJ, Alban TJ, Sinyuk M, Thiagarajan PS, Jarrar AM, Turaga SM, Saygin C, Mulkearns-Hubert E, Hitomi M, Rich JN, Gerson SL, Lathia JD, Liu H. New Advances and Challenges of Targeting Cancer Stem Cells. Cancer Res. 2017 10 01; 77(19):5222-5227. PMID: 28928129; PMCID: PMC5833988.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    37. Saygin C, Wiechert A, Rao VS, Alluri R, Connor E, Thiagarajan PS, Hale JS, Li Y, Chumakova A, Jarrar A, Parker Y, Lindner DJ, Nagaraj AB, Kim JJ, DiFeo A, Abdul-Karim FW, Michener C, Rose PG, DeBernardo R, Mahdi H, McCrae KR, Lin F, Lathia JD, Reizes O. CD55 regulates self-renewal and cisplatin resistance in endometrioid tumors. J Exp Med. 2017 Sep 04; 214(9):2715-2732. PMID: 28838952; PMCID: PMC5584126.
      Citations: 37     Fields:    Translation:AnimalsCells
    38. Saygin C, Jia X, Hill B, Dean R, Pohlman B, Smith MR, Jagadeesh D. Impact of comorbidities on outcomes of elderly patients with diffuse large B-cell lymphoma. Am J Hematol. 2017 Oct; 92(10):989-996. PMID: 28612386.
      Citations: 13     Fields:    Translation:Humans
    39. Saygin C, Papadantonakis N, Cassaday RD, Liedtke M, Fischer K, Dunn T, Patel BJ, Sobecks R, Kalaycio M, Sekeres MA, Mukherjee S, Gerds AT, Hamilton BK, Carraway HE, Advani AS. Prognostic impact of incomplete hematologic count recovery and minimal residual disease on outcome in adult acute lymphoblastic leukemia at the time of second complete response. Leuk Lymphoma. 2018 02; 59(2):363-371. PMID: 28693363.
      Citations: 1     Fields:    Translation:Humans
    40. Patel BJ, Przychodzen B, Thota S, Radivoyevitch T, Visconte V, Kuzmanovic T, Clemente M, Hirsch C, Morawski A, Souaid R, Saygin C, Nazha A, Demarest B, LaFramboise T, Sakaguchi H, Kojima S, Carraway HE, Ogawa S, Makishima H, Sekeres MA, Maciejewski JP. Genomic determinants of chronic myelomonocytic leukemia. Leukemia. 2017 12; 31(12):2815-2823. PMID: 28555081; PMCID: PMC8370480.
      Citations: 44     Fields:    Translation:Humans
    41. Saygin C, Carraway HE. Emerging therapies for acute myeloid leukemia. J Hematol Oncol. 2017 04 18; 10(1):93. PMID: 28420416; PMCID: PMC5395764.
      Citations: 69     Fields:    Translation:Humans
    42. Schmidt S, Goros M, Parsons HM, Saygin C, Wan HD, Shireman PK, Gelfond JAL. Improving Initiation and Tracking of Research Projects at an Academic Health Center: A Case Study. Eval Health Prof. 2017 09; 40(3):372-379. PMID: 27653774; PMCID: PMC5813810.
      Citations: 5     Fields:    Translation:Humans
    43. Wiechert A, Saygin C, Thiagarajan PS, Rao VS, Hale JS, Gupta N, Hitomi M, Nagaraj AB, DiFeo A, Lathia JD, Reizes O. Cisplatin induces stemness in ovarian cancer. Oncotarget. 2016 May 24; 7(21):30511-22. PMID: 27105520; PMCID: PMC5058697.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    44. Saygin C, Samour M, Chumakova A, Jarrar A, Lathia JD, Reizes O. Reporter Systems to Study Cancer Stem Cells. Methods Mol Biol. 2016; 1516:319-333. PMID: 27221339.
      Citations: 9     Fields:    Translation:HumansCells
    45. Ipekci T, Ozden F, Unal B, Saygin C, Uzunaslan D, Ates E. Epithelial-Mesenchymal Transition Markers ß-catenin, Snail, and E-Cadherin do not Predict Disease Free Survival in Prostate Adenocarcinoma: a Prospective Study. Pathol Oncol Res. 2015 Sep; 21(4):1209-16. PMID: 26037169.
      Citations: 4     Fields:    Translation:Humans
    46. Saygin C, Uzunaslan D, Hatemi G, Hamuryudan V. Suicidal ideation among patients with Behçet's syndrome. Clin Exp Rheumatol. 2015 Nov-Dec; 33(6 Suppl 94):S30-5. PMID: 25797433.
      Citations: 4     Fields:    Translation:Humans
    47. Roach EC, Olayan M, Unlu O, Saygin C, Shatnawei A. Schwachman-Diamond syndrome: Increased risk for autoimmune diseases? Clin Res Hepatol Gastroenterol. 2015 Sep; 39(4):e49-50. PMID: 25636239.
      Citations:    Fields:    Translation:Humans
    48. Saygin C, Uzunaslan D, Hatemi G. Currently Used Biologic Agents in the Management of Behcet's Syndrome. Curr Med Chem. 2015; 22(16):1976-85. PMID: 25666786.
      Citations: 3     Fields:    Translation:Humans
    49. Saygin C, Uzunaslan D, Ugurlu S. Antineutrophil cytoplasmic antibody-associated neutropenia in a patient with type 1 diabetes mellitus. Lab Hematol. 2014 Jun; 20(2):7-8. PMID: 25000946.
      Citations: 1     Fields:    Translation:Humans
    50. Koka A, Saygin C, Uzunaslan D, Ozdemir N, Apak H, Celkan T. A 17-year experience with ALL-BFM protocol in acute lymphoblastic leukemia: prognostic predictors and interruptions during protocol. Leuk Res. 2014 Jun; 38(6):699-705. PMID: 24720908.
      Citations: 1     Fields:    Translation:Humans
    51. Uzunaslan D, Saygin C, Hatemi G, Tascilar K, Yazici H. No appreciable decrease in fertility in Behçet's syndrome. Rheumatology (Oxford). 2014 May; 53(5):828-33. PMID: 24369417.
      Citations: 8     Fields:    Translation:Humans
    52. Saygin C, Uzunaslan D, Ozguroglu M, Senocak M, Tuzuner N. Dendritic cell sarcoma: a pooled analysis including 462 cases with presentation of our case series. Crit Rev Oncol Hematol. 2013 Nov; 88(2):253-71. PMID: 23755890.
      Citations: 88     Fields:    Translation:HumansCells
    53. Ozden F, Saygin C, Uzunaslan D, Onal B, Durak H, Aki H. Expression of MMP-1, MMP-9 and TIMP-2 in prostate carcinoma and their influence on prognosis and survival. J Cancer Res Clin Oncol. 2013 Aug; 139(8):1373-82. PMID: 23708302.
      Citations: 28     Fields:    Translation:Humans
    54. Aki H, Uzunaslan D, Saygin C, Batur S, Tuzuner N, Kafadar A, Ongoren S, Oz B. Primary central nervous system lymphoma in immunocompetent individuals: a single center experience. Int J Clin Exp Pathol. 2013; 6(6):1068-75. PMID: 23696924; PMCID: PMC3657359.
      Citations: 8     Fields:    Translation:Humans
    55. Uzunaslan D, Saygin C, Gungor S, Hasiloglu Z, Ozdemir N, Celkan T. Novel use of propranolol for management of pain in children with vertebral hemangioma: report of two cases. Childs Nerv Syst. 2013 May; 29(5):855-60. PMID: 23306960.
      Citations: 2     Fields:    Translation:Humans
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