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Melissa Tjota

TitleAssistant Professor
InstitutionUniversity of Chicago
DepartmentPathology
AddressChicago IL 60637
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Cannova JM, Battaglia MR, Roloff GW, Cetin S, Tallarico M, Stock W, Patel AA, Odenike O, Larson RA, Thirman MJ, Nawas MT, Wang P, Tjota MY, Segal JP, Venkataraman G, DuVall AS, Drazer MW. Hematologic complications in patients exposed to poly-ADP ribose polymerase inhibitors. Haematologica. 2026 Jan 29. PMID: 41609051.
      Citations:    Fields:    
    2. Yasin I, Stengel A, Shao H, Kaur A, Mason EF, Patwardhan PP, Bailey NG, Ghosh S, Inamdar KV, Patel AA, Pandiri M, Zhang J, Sojitra P, Tariq H, Pan Z, Wiredja D, Wang P, Tjota MY, Segal JP, Chang H, Sallman DA, Arber DA, Tefferi A, Badar T, Perry AM, Haferlach C, Lager AM, Venkataraman G. Characterization of chromosome 5 aberrations in TP53 mutated myeloid neoplasms with =5% blasts: An International TP53 Investigators Network (iTiN) study. Cancer. 2026 Jan 01; 132(1):e70210. PMID: 41417597; PMCID: PMC12716622.
      Citations:    Fields:    Translation:HumansCells
    3. Tjota MY, Kwon JW, Wanjari P, Antic T. Papillary renal cell carcinoma, formerly known as Type 2: a single institutional study addressing histologic and molecular features. Histopathology. 2026 Apr; 88(5):1044-1050. PMID: 41400361; PMCID: PMC12975658.
      Citations:    Fields:    
    4. Kwon JW, Tjota MY, Antic T. MTOR-mutated eosinophilic renal cell carcinomas with loss of chromosome 1 and high metastatic potential: further expanding the spectrum of TSC/mTOR pathway mutated renal tumors. Virchows Arch. 2025 Nov 27. PMID: 41299159.
      Citations:    Fields:    
    5. Harris EJ, Karaoglu DA, Sukhanova M, Abaza Y, Karantanos T, Eisfeld AK, Anderson C, Lin C, Moreno Vanegas YA, Badar T, Coltoff A, Knepper TC, Ozkaya N, Youshanlouei HR, Cetin S, Patel AA, DuVall AS, Drazer MW, Wang P, Tjota M, Segal JP, Venkataraman G, Gurbuxani S, Cheng JX, Arber DA, Larson RA, Odenike O, Webster J, Shah B, Stock W, Saygin C. Clinical and molecular characterization of TP53-mutant acute lymphoblastic leukemia in adults. Blood Cancer J. 2025 Aug 14; 15(1):138. PMID: 40813576; PMCID: PMC12354737.
      Citations: 3     Fields:    Translation:Humans
    6. Kwon JW, Wang P, Wanjari P, Wuori D, Paik J, Pytel P, Fitzpatrick C, Tjota MY, Antic T. Renal Tumorigenesis via RAS/RAF/MAPK Pathway Alterations Beyond Papillary Renal Neoplasm With Reverse Polarity. Am J Surg Pathol. 2025 Dec 01; 49(12):1266-1278. PMID: 40557814.
      Citations: 2     Fields:    Translation:HumansCells
    7. Jafari P, Forrest ME, Segal J, Wang P, Tjota MY. Corrigendum to "Pan-Cancer Molecular Biomarkers: Practical Considerations for the Surgical Pathologist" [Modern Pathology 38 (2025) 100752]. Mod Pathol. 2025 Jun; 38(6):100773. PMID: 40377506.
      Citations:    Fields:    
    8. Storozuk T, Tjota M, Ntiamoah P, Wanjari P, Biernacka A, Reeves W, Antic T, Storozuk T, Tjota M, Ntiamoah P, Wanjari P, Biernacka A, Reeves W, Antic T. Primary Melanoma of the Lung: A Vanishing Entity. Acta Cytol. 2025; 69(4):361-366. PMID: 40373758.
      Citations:    Fields:    Translation:Humans
    9. Ma LX, Bennett JA, Tjota MY, Momeni-Boroujeni A, Ordulu Z, Meserve E, Skala SL, Huang T, Chapel DB. Comparative Molecular Profiling of "Mixed Endometrioid Adenocarcinoma and Adenosarcoma" of the Uterus and Ovary: A Multi-institutional Series of 14 Cases. Am J Surg Pathol. 2025 Apr 07; 49(8):789-799. PMID: 40192107.
      Citations:    Fields:    Translation:Humans
    10. Nguyen T, Tjota M, Wang P, Tatjana A. A Case Report of INI1 Loss and SMARCB1 Mutation in Hereditary Succinate Dehydrogenase-Deficient Renal Cell Carcinoma. Int J Surg Pathol. 2025 Sep; 33(6):1541-1546. PMID: 40094795.
      Citations:    Fields:    Translation:Humans
    11. Jafari P, Forrest M, Segal J, Wang P, Tjota MY, Forrest ME. Pan-Cancer Molecular Biomarkers: Practical Considerations for the Surgical Pathologist. Mod Pathol. 2025 Jun; 38(6):100752. PMID: 40058460.
      Citations: 1     Fields:    Translation:Humans
    12. Kwon JW, Nguyen TD, Tjota MY, Antic T. GATA3 Expression in Solid Vimentin-Negative Eosinophilic Renal Epithelial Tumors-A Comprehensive Study of 48 Tumors. Int J Surg Pathol. 2025 Jun; 33(4):820-827. PMID: 39523674.
      Citations: 2     Fields:    Translation:Humans
    13. Gupta S, McCarthy MR, Tjota MY, Antic T, Cheville JC. Metastatic renal cell carcinoma with fibromyomatous stroma associated with tuberous sclerosis or MTOR, TSC1/TSC2-Mutations: A Series of 4 cases and a review of the literature. Hum Pathol. 2024 Nov; 153:105680. PMID: 39522702.
      Citations: 5     Fields:    Translation:Humans
    14. Kaur A, Rojek AE, Symes E, Nawas MT, Patel AA, Patel JL, Sojitra P, Aqil B, Sukhanova M, McNerney ME, Wu LP, Akmatbekov A, Segal J, Tjota MY, Gurbuxani S, Cheng JX, Yeon SY, Ravisankar HV, Fitzpatrick C, Lager A, Drazer MW, Saygin C, Wanjari P, Katsonis P, Lichtarge O, Churpek JE, Ghosh SB, Patel AB, Menon MP, Arber DA, Wang P, Venkataraman G. Real world predictors of response and 24-month survival in high-grade TP53-mutated myeloid neoplasms. Blood Cancer J. 2024 06 18; 14(1):99. PMID: 38890297; PMCID: PMC11189545.
      Citations: 7     Fields:    Translation:Humans
    15. Tjota MY, Segal JP, Wang P. Clinical Utility and Benefits of Comprehensive Genomic Profiling in Cancer. J Appl Lab Med. 2024 01 03; 9(1):76-91. PMID: 38167763.
      Citations: 18     Fields:    Translation:Humans
    16. Symes E, Tjota M, Cody B, Kindler H, Mitchell O, Witmer H, Turaga K, Mueller J, Krausz T, Husain AN, Li H. Mesothelioma in situ of the peritoneum: report of three cases and review of the literature. Histopathology. 2024 Feb; 84(3):492-506. PMID: 38084880.
      Citations: 3     Fields:    Translation:Humans
    17. Setia N, Del Gaudio D, Kandikatla P, Arndt K, Tjota M, Wang P, Segal J, Alikhan M, Hart J. A novel telomere biology disease-associated gastritis identified through a whole exome sequencing-driven approach. J Pathol Clin Res. 2024 01; 10(1):e349. PMID: 37994393; PMCID: PMC10766041.
      Citations: 1     Fields:    Translation:Humans
    18. Chen-Yost HI, Schulte JJ, Tjota MY, Gao G, Mitchell O, Kindler H, Segal J, Husain AN, Mueller J. Characterizing the distribution of alterations in mesothelioma and their correlation to morphology. Am J Clin Pathol. 2023 09 01; 160(3):238-246. PMID: 37141416.
      Citations: 3     Fields:    Translation:Humans
    19. Mitchell OD, Gilliam K, Del Gaudio D, McNeely KE, Smith S, Acevedo M, Gaduraju M, Hodge R, Ramsland ASS, Segal J, Das S, Hathaway F, Bryan DS, Tawde S, Galasinski S, Wang P, Tjota MY, Husain AN, Armato SG, Donington J, Ferguson MK, Turaga K, Churpek JE, Kindler HL, Drazer MW. Germline Variants Incidentally Detected via Tumor-Only Genomic Profiling of Patients With Mesothelioma. JAMA Netw Open. 2023 08 01; 6(8):e2327351. PMID: 37556141; PMCID: PMC10413174.
      Citations: 6     Fields:    Translation:Humans
    20. Doytcheva K, Storozuk T, Tjota M, Antic T. Oncocytoma-Like Angiomyolipoma of the Kidney: A Closer Look into the Clinicopathologic, Immunohistochemical, and Molecular Characteristics of a Rare Entity with Review of the Literature. Int J Surg Pathol. 2024 May; 32(3):625-631. PMID: 37487196.
      Citations:    Fields:    Translation:Humans
    21. Mendoza RP, Wang P, Schulte JJ, Tjota MY, Jani I, Martinez AC, Haridas R, Wanjari P, Steinhardt G, Brown N, Betz BL, Chapel DB, Kertowidjojo E, Yamada SD, Bennett JA. Endometrial Carcinomas With Subclonal Loss of Mismatch Repair Proteins: A Clinicopathologic and Genomic Study. Am J Surg Pathol. 2023 05 01; 47(5):589-598. PMID: 36866757.
      Citations: 6     Fields:    Translation:HumansCells
    22. Kaumeyer BA, Tjota MY, Parker K, Chan CW, Gant Kanegusuku A, Baldwin AD, Yeo KJ. Use of a Vanadate Oxidation Conjugated Bilirubin Assay to Reduce Test Cancellations Resulting from Hemolyzed Specimens in Pediatric Patients. Am J Clin Pathol. 2023 01 04; 159(1):6-9. PMID: 36413387.
      Citations: 1     Fields:    Translation:Humans
    23. Tjota MY, Sharma A, Wanjari P, Fitzpatrick C, Segal J, Antic T. TSC/MTOR mutated renal cell carcinoma with leiomyomatous stroma is a distinct entity: a comprehensive study of 12 cases. Hum Pathol. 2023 04; 134:124-133. PMID: 36592877.
      Citations: 6     Fields:    Translation:Humans
    24. Paintal A, Tjota MY, Wang P, Fitzpatrick C, Wanjari P, Stadler WM, Gallan AJ, Segal J, Antic T. NF2-mutated Renal Carcinomas Have Common Morphologic Features Which Overlap With Biphasic Hyalinizing Psammomatous Renal Cell Carcinoma: A Comprehensive Study of 14 Cases. Am J Surg Pathol. 2022 05 01; 46(5):617-627. PMID: 35034039.
      Citations: 6     Fields:    Translation:Humans
    25. Siddiqui F, Perez Silos V, Karube K, Yasin Goksu S, Nandakumar S, Saygin C, Onajin O, Prabu SS, Gurbuxani S, Arber DA, Tjota M, Segal J, Smith SM, Murga-Zamalloa CA, Venkataraman G. B-cell lymphoma-2 downregulation is a useful feature supporting a neoplastic phenotype in mature T-cell lymphomas. Hum Pathol. 2022 07; 125:48-58. PMID: 35452696.
      Citations: 2     Fields:    Translation:HumansCells
    26. Tatjana A, Tjota MY, O'Donnell PH, Eggener SE, Agarwal PK, Haridas R, Segal J, Wang P. EZR-ROS1 fusion renal cell carcinoma mimicking urothelial carcinoma: report of a previously undescribed gene fusion in renal cell carcinoma. Virchows Arch. 2022 Feb; 480(2):487-492. PMID: 34128116.
      Citations: 4     Fields:    Translation:Humans
    27. Cho JH, Wool GD, Tjota MY, Gutierrez J, Mikrut K, Miller JL. Functional Assessment of Platelet Dense Granule ATP Release. Am J Clin Pathol. 2021 05 18; 155(6):863-872. PMID: 33386737.
      Citations: 1     Fields:    Translation:HumansCells
    28. Tjota MY, Segal J, Stadler WM, Antic T. Eosinophilic renal cell carcinoma with isolated MTOR mutation metastatic to the liver: a novel case. Pathology. 2021 Oct; 53(6):790-793. PMID: 33509639.
      Citations: 3     Fields:    Translation:Humans
    29. Tjota MY, Wanjari P, Segal J, Antic T. TSC/MTOR-mutated eosinophilic renal tumors are a distinct entity that is CK7+/CK20-/vimentin-: a validation study. Hum Pathol. 2021 09; 115:84-95. PMID: 33352195.
      Citations: 13     Fields:    Translation:Humans
    30. Tjota M, Chen H, Parilla M, Wanjari P, Segal J, Antic T. Eosinophilic Renal Cell Tumors With a TSC and MTOR Gene Mutations Are Morphologically and Immunohistochemically Heterogenous: Clinicopathologic and Molecular Study. Am J Surg Pathol. 2020 07; 44(7):943-954. PMID: 32091432.
      Citations: 25     Fields:    Translation:HumansCells
    31. Tjota MY, Pytel P. Educational Case: Pilocytic Astrocytoma With Atypical Features. Acad Pathol. 2020 Jan-Dec; 7:2374289520912498. PMID: 32284965; PMCID: PMC7119228.
      Citations: 1     
    32. Olson DJ, Rajagopal P, Tjota MY, Venkataraman G, Luke JJ, Gajewski TF. A case of dual-mechanism immune-related anaemia in a patient with metastatic melanoma treated with nivolumab and ipilimumab. J Immunother Cancer. 2020 03; 8(1). PMID: 32169870; PMCID: PMC7069276.
      Citations: 4     Fields:    Translation:Humans
    33. Rosen LE, Karrison T, Ananthanarayanan V, Gallan AJ, Adusumilli PS, Alchami FS, Attanoos R, Brcic L, Butnor KJ, Hiroshima K, Kadota K, Klampatsa A, Lindenmann J, Litzky LA, Marchevsky A, Medeiros F, Montero MA, Moore DA, Nabeshima K, Pavlisko EN, Roggli VL, Sauter JL, Sharma A, Sheaff M, Travis WD, Vigneswaran WT, Vrugt B, Walts AE, Tjota MY, Krausz T, Husain AN, Galateau-Sallé F, Stang NL. Nuclear grade and necrosis predict prognosis in malignant epithelioid pleural mesothelioma: a multi-institutional study. Mod Pathol. 2018 04; 31(4):598-606. PMID: 29327706.
      Citations: 42     Fields:    Translation:HumansCells
    34. Tjota MY, Camacho DF, Turnquist HR, Sperling AI. IL-33 Drives Monocyte Recruitment to Lung Interstitium through Chemokine Upregulation. Immunohorizons. 2017 Aug 01; 1(6):101-108. PMID: 29629429; PMCID: PMC5889047.
      Citations: 5     Fields:    
    35. Hrusch CL, Manns ST, Bryazka D, Casaos J, Bonham CA, Jaffery MR, Blaine KM, Mills KAM, Verhoef PA, Adegunsoye AO, Williams JW, Tjota MY, Moore TV, Strek ME, Noth I, Sperling AI. ICOS protects against mortality from acute lung injury through activation of IL-5+ ILC2s. Mucosal Immunol. 2018 01; 11(1):61-70. PMID: 28488693; PMCID: PMC5681437.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    36. Hrusch CL, Tjota MY, Sperling AI. The role of dendritic cells and monocytes in the maintenance and loss of respiratory tolerance. Curr Allergy Asthma Rep. 2015 Jan; 15(1):494. PMID: 25430955; PMCID: PMC4737703.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    37. Tjota MY, Sperling AI. Distinct dendritic cell subsets actively induce Th2 polarization. Curr Opin Immunol. 2014 Dec; 31:44-50. PMID: 25290173; PMCID: PMC4737705.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    38. Stefka AT, Feehley T, Tripathi P, Qiu J, McCoy K, Mazmanian SK, Tjota MY, Seo GY, Cao S, Theriault BR, Antonopoulos DA, Zhou L, Chang EB, Fu YX, Nagler CR. Commensal bacteria protect against food allergen sensitization. Proc Natl Acad Sci U S A. 2014 Sep 09; 111(36):13145-50. PMID: 25157157; PMCID: PMC4246970.
      Citations: 395     Fields:    Translation:AnimalsCellsPHPublic Health
    39. Tjota MY, Hrusch CL, Blaine KM, Williams JW, Barrett NA, Sperling AI. Signaling through FcR?-associated receptors on dendritic cells drives IL-33-dependent TH2-type responses. J Allergy Clin Immunol. 2014 Sep; 134(3):706-713.e8. PMID: 25088053; PMCID: PMC4149927.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    40. Tjota MY, Williams JW, Lu T, Clay BS, Byrd T, Hrusch CL, Decker DC, de Araujo CA, Bryce PJ, Sperling AI. IL-33-dependent induction of allergic lung inflammation by Fc?RIII signaling. J Clin Invest. 2013 May; 123(5):2287-97. PMID: 23585480; PMCID: PMC3635716.
      Citations: 48     Fields:    Translation:AnimalsCells
    41. Williams JW, Tjota MY, Clay BS, Vander Lugt B, Bandukwala HS, Hrusch CL, Decker DC, Blaine KM, Fixsen BR, Singh H, Sciammas R, Sperling AI. Transcription factor IRF4 drives dendritic cells to promote Th2 differentiation. Nat Commun. 2013; 4:2990. PMID: 24356538; PMCID: PMC4003872.
      Citations: 226     Fields:    Translation:AnimalsCells
    42. Williams JW, Tjota MY, Sperling AI. The contribution of allergen-specific IgG to the development of th2-mediated airway inflammation. J Allergy (Cairo). 2012; 2012:236075. PMID: 23150737; PMCID: PMC3485540.
      Citations: 29     
    43. Parekkadan B, Fletcher AL, Li M, Tjota MY, Bellemare-Pelletier A, Milwid JM, Lee JW, Yarmush ML, Turley SJ. Aire controls mesenchymal stem cell-mediated suppression in chronic colitis. Mol Ther. 2012 Jan; 20(1):178-86. PMID: 21952165; PMCID: PMC3255580.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    44. Tjota MY, Kozak BM, Chang EM, Close KL. 4th International Conference on Advanced Technologies and Treatments for Diabetes. J Diabetes. 2011 Jun; 3(2):95-102. PMID: 21599863.
      Citations: 1     Fields:    Translation:Humans
    45. Yarchoan M, Dougan ML, Tjota MY, Milliner BH, Adler BL, Armah KA, Gooley TA, Close KL, Close J, Hirsch IB. Who will manage American patients with diabetes? Residents' career preferences and perceptions of diabetes care. Endocr Pract. 2011 Mar-Apr; 17(2):235-9. PMID: 21041164.
      Citations: 2     Fields:    Translation:Humans
    46. Kozak BM, Tjota MY, Close KL. Diabetes News. J Diabetes. 2010 Dec 07. PMID: 21138543.
      Citations:    Fields:    
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