Pick Disease of the Brain
"Pick Disease of the Brain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A rare form of DEMENTIA that is sometimes familial. Clinical features include APHASIA; APRAXIA; CONFUSION; ANOMIA; memory loss; and personality deterioration. This pattern is consistent with the pathologic findings of circumscribed atrophy of the poles of the FRONTAL LOBE and TEMPORAL LOBE. Neuronal loss is maximal in the HIPPOCAMPUS, entorhinal cortex, and AMYGDALA. Some ballooned cortical neurons contain argentophylic (Pick) bodies. (From Brain Pathol 1998 Apr;8(2):339-54; Adams et al., Principles of Neurology, 6th ed, pp1057-9)
Descriptor ID |
D020774
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MeSH Number(s) |
C10.228.140.380.615 F03.087.400.675
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Concept/Terms |
Pick Disease of the Brain- Pick Disease of the Brain
- Circumscribed Lobar Atrophy of the Brain
- Lobar Atrophy (Brain)
- Atrophies, Lobar (Brain)
- Atrophy, Lobar (Brain)
- Lobar Atrophies (Brain)
- Dementia with Lobar Atrophy and Neuronal Cytoplasmic Inclusions
- Pick Disease
- Disease, Pick
- Pick's Disease
- Disease, Pick's
- Picks Disease
- Picks Disease of Brain
- Brain Atrophy, Circumscribed Lobar
- Lobar Atrophy of the Brain
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Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pick Disease of the Brain" by people in Profiles.
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Hogg M, Grujic ZM, Baker M, Demirci S, Guillozet AL, Sweet AP, Herzog LL, Weintraub S, Mesulam MM, LaPointe NE, Gamblin TC, Berry RW, Binder LI, de Silva R, Lees A, Espinoza M, Davies P, Grover A, Sahara N, Ishizawa T, Dickson D, Yen SH, Hutton M, Bigio EH. The L266V tau mutation is associated with frontotemporal dementia and Pick-like 3R and 4R tauopathy. Acta Neuropathol. 2003 Oct; 106(4):323-36.
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