Pick Disease of the Brain
"Pick Disease of the Brain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A rare form of DEMENTIA that is sometimes familial. Clinical features include APHASIA; APRAXIA; CONFUSION; ANOMIA; memory loss; and personality deterioration. This pattern is consistent with the pathologic findings of circumscribed atrophy of the poles of the FRONTAL LOBE and TEMPORAL LOBE. Neuronal loss is maximal in the HIPPOCAMPUS, entorhinal cortex, and AMYGDALA. Some ballooned cortical neurons contain argentophylic (Pick) bodies. (From Brain Pathol 1998 Apr;8(2):339-54; Adams et al., Principles of Neurology, 6th ed, pp1057-9)
| Descriptor ID |
D020774
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| MeSH Number(s) |
C10.228.140.380.266.299.500 F03.615.400.380.299.500
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| Concept/Terms |
Pick Disease of the Brain- Pick Disease of the Brain
- Brain Atrophy, Circumscribed Lobar
- Pick Disease
- Disease, Pick
- Picks Disease of Brain
- Lobar Atrophy Of Brain
- Pick's Disease
- Disease, Pick's
- Picks Disease
- Lobar Atrophy of the Brain
- Dementia with Lobar Atrophy and Neuronal Cytoplasmic Inclusions
- Pick Disease Of Brain
- Lobar Atrophy (Brain)
- Atrophies, Lobar (Brain)
- Atrophy, Lobar (Brain)
- Lobar Atrophies (Brain)
- Circumscribed Lobar Atrophy of the Brain
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Below are MeSH descriptors whose meaning is more general than "Pick Disease of the Brain".
Below are MeSH descriptors whose meaning is more specific than "Pick Disease of the Brain".
This graph shows the total number of publications written about "Pick Disease of the Brain" by people in this website by year, and whether "Pick Disease of the Brain" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pick Disease of the Brain" by people in Profiles.
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Phenotypically concordant distribution of pick bodies in aphasic versus behavioral dementias. Acta Neuropathol Commun. 2024 Feb 22; 12(1):31.
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Translation of dipeptide repeat proteins in C9ORF72 ALS/FTD through unique and redundant AUG initiation codons. Elife. 2023 09 07; 12.
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Neuropathological fingerprints of survival, atrophy and language in primary progressive aphasia. Brain. 2022 06 30; 145(6):2133-2148.
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The L266V tau mutation is associated with frontotemporal dementia and Pick-like 3R and 4R tauopathy. Acta Neuropathol. 2003 Oct; 106(4):323-36.