Thyrotropin, beta Subunit
"Thyrotropin, beta Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The beta subunit of thyroid stimulating hormone, thyrotropin. It is a 112-amino acid glycopolypeptide of about 16 kD. Full biological activity of TSH requires the non-covalently bound heterodimers of an alpha and a beta subunit.
Descriptor ID |
D037322
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MeSH Number(s) |
D06.472.699.631.525.883.500 D12.644.548.691.525.883.500
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Concept/Terms |
Thyrotropin, beta Subunit- Thyrotropin, beta Subunit
- Thyrotropin, beta Chain
- Thyroid Stimulating Hormone, beta Subunit
- TSHB Gene Product
- Thyrotropin-beta
- Thyrotropin beta
- TSH, beta Subunit
- TSH-beta
- TSH beta
- TSH, beta Chain
- Thyrotropin, beta Polypeptide Chain
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Below are MeSH descriptors whose meaning is more general than "Thyrotropin, beta Subunit".
Below are MeSH descriptors whose meaning is more specific than "Thyrotropin, beta Subunit".
This graph shows the total number of publications written about "Thyrotropin, beta Subunit" by people in this website by year, and whether "Thyrotropin, beta Subunit" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 1 | 1 |
2004 | 1 | 0 | 1 |
2007 | 0 | 1 | 1 |
2015 | 1 | 0 | 1 |
2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Thyrotropin, beta Subunit" by people in Profiles.
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Central Congenital Hypothyroidism Caused by a Novel Mutation, C47W, in the Cysteine Knot Region of TSHß. Horm Res Paediatr. 2019; 92(6):390-394.
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A TSHß Variant with Impaired Immunoreactivity but Intact Biological Activity and Its Clinical Implications. Thyroid. 2015 Aug; 25(8):869-76.
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Pituitary-thyroid setpoint and thyrotropin receptor expression in consomic rats. Endocrinology. 2007 Oct; 148(10):4727-33.
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Four new cases of congenital secondary hypothyroidism due to a splice site mutation in the thyrotropin-beta gene: phenotypic variability and founder effect. J Clin Endocrinol Metab. 2004 Aug; 89(8):4136-41.
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Thyroid hormone receptor-specific interactions with steroid receptor coactivator-1 in the pituitary. Mol Endocrinol. 2003 May; 17(5):882-94.