 Vascular Endothelial Growth Factor Receptor-1
"Vascular Endothelial Growth Factor Receptor-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 180-kDa VEGF receptor found primarily in endothelial cells that is essential for vasculogenesis and vascular maintenance. It is also known as Flt-1 (fms-like tyrosine kinase receptor-1). A soluble, alternatively spliced isoform of the receptor may serve as a binding protein that regulates the availability of various ligands for VEGF receptor binding and signal transduction.
| Descriptor ID |
D040281
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| MeSH Number(s) |
D08.811.913.696.620.682.725.400.950.100 D12.776.543.750.060.750.100 D12.776.543.750.750.400.910.100
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| Concept/Terms |
Vascular Endothelial Growth Factor Receptor-1- Vascular Endothelial Growth Factor Receptor-1
- Vascular Endothelial Growth Factor Receptor 1
- FLT1 RTK
- VEGFR-1
- Proto-Oncogene Protein flt
- Proto Oncogene Protein flt
- VEGF Receptor flt-1 Protein
- VEGF Receptor flt 1 Protein
- VEGF Receptor, FLT
- FLT VEGF Receptor
- Receptor, FLT VEGF
- FLT1 Receptor Tyrosine Kinase
- fms-Like Tyrosine Kinase
- Tyrosine Kinase, fms-Like
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Below are MeSH descriptors whose meaning is more general than "Vascular Endothelial Growth Factor Receptor-1".
Below are MeSH descriptors whose meaning is more specific than "Vascular Endothelial Growth Factor Receptor-1".
This graph shows the total number of publications written about "Vascular Endothelial Growth Factor Receptor-1" by people in this website by year, and whether "Vascular Endothelial Growth Factor Receptor-1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2001 | 0 | 2 | 2 | | 2005 | 0 | 1 | 1 | | 2006 | 1 | 1 | 2 | | 2007 | 4 | 2 | 6 | | 2008 | 1 | 1 | 2 | | 2009 | 3 | 0 | 3 | | 2010 | 2 | 1 | 3 | | 2011 | 3 | 2 | 5 | | 2012 | 5 | 2 | 7 | | 2013 | 5 | 2 | 7 | | 2014 | 3 | 0 | 3 | | 2015 | 3 | 3 | 6 | | 2016 | 3 | 2 | 5 | | 2017 | 2 | 2 | 4 | | 2018 | 3 | 0 | 3 | | 2020 | 4 | 1 | 5 | | 2021 | 2 | 3 | 5 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Vascular Endothelial Growth Factor Receptor-1" by people in Profiles.
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Docheva N, Arenas G, Nieman KM, Lopes-Perdigao J, Yeo KJ, Rana S. Angiogenic Biomarkers for Risk Stratification in Women with Preeclampsia. Clin Chem. 2022 Jun 01; 68(6):771-781.
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Verlohren S, Brennecke SP, Galindo A, Karumanchi SA, Mirkovic LB, Schlembach D, Stepan H, Vatish M, Zeisler H, Rana S. Clinical interpretation and implementation of the sFlt-1/PlGF ratio in the prediction, diagnosis and management of preeclampsia. Pregnancy Hypertens. 2022 Mar; 27:42-50.
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Khosla K, Espinoza J, Perlaza L, Gencay M, Mueller AL, Harris JM, Wolf C, Posnett JW, Woelkers DA, Rana S. Cost effectiveness of the sFlt1/PlGF ratio test as an adjunct to the current practice of evaluating suspected preeclampsia in the United States. Pregnancy Hypertens. 2021 Dec; 26:121-126.
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Johnson KM, Smith L, Modest AM, Salahuddin S, Karumanchi SA, Rana S, Young BC. Angiogenic factors and prediction for ischemic placental disease in future pregnancies. Pregnancy Hypertens. 2021 Aug; 25:12-17.
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Njoroge S, Kuriloff M, Mueller A, Lopes Perdigao J, Dhir R, Rana S. The interval between births and the risk of recurrent preeclampsia among predominantly high risk women in urban tertiary care center. Pregnancy Hypertens. 2021 Aug; 25:7-11.
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Arenas GA, Tang NY, Mueller A, Lopes Perdigao J, Kaur H, Abramowicz JS, Mussatt K, Yeo KJ, Rana S. Use of the angiogenic biomarker profile to risk stratify patients with fetal growth restriction. Am J Obstet Gynecol MFM. 2021 07; 3(4):100394.
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Soundararajan R, Suresh SC, Mueller A, Heimberger S, Avula S, Sathyanarayana C, Mahesh S, Madhuprakash S, Rana S. Real life outpatient biomarker use in management of hypertensive pregnancies in third trimester in a low resource SeTting: ROBUST study. Pregnancy Hypertens. 2021 Mar; 23:97-103.
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Rana S, Burke SD, Karumanchi SA. Imbalances in circulating angiogenic factors in the pathophysiology of preeclampsia and related disorders. Am J Obstet Gynecol. 2022 02; 226(2S):S1019-S1034.
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Suresh S, Mueller A, Salahuddin S, Naseem H, Dhir R, Rana S. Evaluation of angiogenic factors in the decision to admit women with suspected preeclampsia. Pregnancy Hypertens. 2020 Jul; 21:124-131.
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Heimberger S, Mueller A, Ratnaparkhi R, Perdigao JL, Rana S. Angiogenic factor abnormalities and risk of peripartum complications and prematurity among urban predominantly obese parturients with chronic hypertension. Pregnancy Hypertens. 2020 Apr; 20:124-130.
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