Actin Depolymerizing Factors
"Actin Depolymerizing Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of low MOLECULAR WEIGHT actin-binding proteins found throughout eukaryotes. They remodel the actin CYTOSKELETON by severing ACTIN FILAMENTS and increasing the rate of monomer dissociation.
| Descriptor ID |
D051339
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| MeSH Number(s) |
D05.750.078.730.212 D12.776.220.525.212
|
| Concept/Terms |
Actin Depolymerizing Factors- Actin Depolymerizing Factors
- Depolymerizing Factors, Actin
- Cofilins
- Cofilin Proteins
- Actin Depolymerizing Proteins
- Depolymerizing Proteins, Actin
- ADF Proteins (Actin Depolymerizing Factors)
|
Below are MeSH descriptors whose meaning is more general than "Actin Depolymerizing Factors".
Below are MeSH descriptors whose meaning is more specific than "Actin Depolymerizing Factors".
This graph shows the total number of publications written about "Actin Depolymerizing Factors" by people in this website by year, and whether "Actin Depolymerizing Factors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2019 | 1 | 1 | 2 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Actin Depolymerizing Factors" by people in Profiles.
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Pseudomonas aeruginosa exoenzyme Y directly bundles actin filaments. J Biol Chem. 2020 03 13; 295(11):3506-3517.
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Cofilin drives rapid turnover and fluidization of entangled F-actin. Proc Natl Acad Sci U S A. 2019 06 25; 116(26):12629-12637.
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Cooperation between tropomyosin and a-actinin inhibits fimbrin association with actin filament networks in fission yeast. Elife. 2019 06 10; 8.
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Competition between Tropomyosin, Fimbrin, and ADF/Cofilin drives their sorting to distinct actin filament networks. Elife. 2017 03 10; 6.
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Minimal requirements for actin filament disassembly revealed by structural analysis of malaria parasite actin-depolymerizing factor 1. Proc Natl Acad Sci U S A. 2011 Jun 14; 108(24):9869-74.
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Fimbrin and tropomyosin competition regulates endocytosis and cytokinesis kinetics in fission yeast. Curr Biol. 2010 Aug 24; 20(16):1415-22.
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Profilin-mediated competition between capping protein and formin Cdc12p during cytokinesis in fission yeast. Mol Biol Cell. 2005 May; 16(5):2313-24.
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Arabidopsis capping protein (AtCP) is a heterodimer that regulates assembly at the barbed ends of actin filaments. J Biol Chem. 2003 Nov 07; 278(45):44832-42.
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Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement. J Clin Invest. 2001 Sep; 108(5):689-701.