"Histones" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small chromosomal proteins (approx 12-20 kD) possessing an open, unfolded structure and attached to the DNA in cell nuclei by ionic linkages. Classification into the various types (designated histone I, histone II, etc.) is based on the relative amounts of arginine and lysine in each.
| Descriptor ID |
D006657
|
| MeSH Number(s) |
D12.776.157.687.485 D12.776.660.720.485 D12.776.664.469
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Histones".
Below are MeSH descriptors whose meaning is more specific than "Histones".
This graph shows the total number of publications written about "Histones" by people in this website by year, and whether "Histones" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 2 | 2 |
| 2001 | 1 | 0 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 2 | 1 | 3 |
| 2004 | 2 | 0 | 2 |
| 2005 | 4 | 3 | 7 |
| 2006 | 5 | 6 | 11 |
| 2007 | 3 | 5 | 8 |
| 2008 | 5 | 4 | 9 |
| 2009 | 4 | 8 | 12 |
| 2010 | 4 | 15 | 19 |
| 2011 | 3 | 15 | 18 |
| 2012 | 10 | 12 | 22 |
| 2013 | 7 | 12 | 19 |
| 2014 | 7 | 9 | 16 |
| 2015 | 7 | 11 | 18 |
| 2016 | 7 | 11 | 18 |
| 2017 | 12 | 10 | 22 |
| 2018 | 4 | 6 | 10 |
| 2019 | 7 | 8 | 15 |
| 2020 | 4 | 6 | 10 |
| 2021 | 3 | 5 | 8 |
| 2022 | 2 | 5 | 7 |
| 2023 | 3 | 3 | 6 |
| 2024 | 4 | 6 | 10 |
| 2025 | 1 | 4 | 5 |
| 2026 | 0 | 7 | 7 |
To return to the timeline,
click here.
Below are the most recent publications written about "Histones" by people in Profiles.
-
Promiscuous RNA binding by WDR5 remodels the KMT2A (MLL1) histone methyltransferase complex to an inactive state. Mol Cell. 2026 Sep 17; 86(18):3740-3758.e9.
-
Comparative genomic analysis and epigenetic profiling of the Drosophila melanogaster B chromosome. Genetics. 2026 08 05; 233(4).
-
Epigenetic regulation in hypertension: mechanistic insights and environmental influences. Am J Hypertens. 2026 Aug 01; 39(8):943-955.
-
Intrinsically disordered regions restrain genomic targeting of RNA and histone demethylases in mammals and plants. Nat Genet. 2026 Aug; 58(8):2013-2026.
-
Neutrophil extracellular trap-related pathology in sporadic brain arteriovenous malformations after radiosurgery: An exploratory histopathological study. Clin Neurol Neurosurg. 2026 Sep; 268:109482.
-
Changes in nuclear and actin mechanics from G1 to G2 affect nuclear integrity. J Cell Sci. 2026 Jun 15; 139(12).
-
Chromatin Profiling Reveals Distinct Male and Female Trajectories for Developmental Learning Potential. Dev Neurobiol. 2026 01; 86(1):e23017.
-
Developing a therapeutic elastase that stimulates anti-tumor immunity by selectively killing cancer cells. Cell Rep Med. 2025 Nov 18; 6(11):102446.
-
Lamin B loss in nuclear blebs is rupture dependent whereas increased DNA damage is rupture independent. J Cell Sci. 2025 11 01; 138(21).
-
Biochemistry and regulation of histone lysine L-lactylation. Nat Rev Mol Cell Biol. 2026 Feb; 27(2):95-109.