"Histones" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small chromosomal proteins (approx 12-20 kD) possessing an open, unfolded structure and attached to the DNA in cell nuclei by ionic linkages. Classification into the various types (designated histone I, histone II, etc.) is based on the relative amounts of arginine and lysine in each.
Descriptor ID |
D006657
|
MeSH Number(s) |
D12.776.157.687.485 D12.776.660.720.485 D12.776.664.469
|
Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Histones".
Below are MeSH descriptors whose meaning is more specific than "Histones".
This graph shows the total number of publications written about "Histones" by people in this website by year, and whether "Histones" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 2 | 2 |
2001 | 1 | 0 | 1 |
2002 | 0 | 2 | 2 |
2003 | 2 | 1 | 3 |
2004 | 2 | 1 | 3 |
2005 | 2 | 3 | 5 |
2006 | 5 | 6 | 11 |
2007 | 3 | 4 | 7 |
2008 | 5 | 3 | 8 |
2009 | 2 | 6 | 8 |
2010 | 3 | 13 | 16 |
2011 | 2 | 14 | 16 |
2012 | 10 | 8 | 18 |
2013 | 7 | 11 | 18 |
2014 | 7 | 8 | 15 |
2015 | 6 | 9 | 15 |
2016 | 4 | 9 | 13 |
2017 | 11 | 8 | 19 |
2018 | 3 | 4 | 7 |
2019 | 4 | 6 | 10 |
2020 | 4 | 4 | 8 |
2021 | 2 | 5 | 7 |
2022 | 0 | 4 | 4 |
2023 | 3 | 2 | 5 |
2024 | 0 | 2 | 2 |
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Below are the most recent publications written about "Histones" by people in Profiles.
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Allele-specific control of rodent and human lncRNA KMT2E-AS1 promotes hypoxic endothelial pathology in pulmonary hypertension. Sci Transl Med. 2024 01 10; 16(729):eadd2029.
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5-Hydroxymethylcytosine Profiling of Cell-Free DNA Identifies Bivalent Genes That Are Prognostic of Survival in High-Risk Neuroblastoma. JCO Precis Oncol. 2024 Jan; 8:e2300297.
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Chromatin compartmentalization regulates the response to DNA damage. Nature. 2023 Nov; 623(7985):183-192.
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Iron drives anabolic metabolism through active histone demethylation and mTORC1. Nat Cell Biol. 2023 Oct; 25(10):1478-1494.
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METTL14 is a chromatin regulator independent of its RNA N6-methyladenosine methyltransferase activity. Protein Cell. 2023 09 14; 14(9):683-697.
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(R)-2-Hydroxyglutarate Inhibits KDM5 Histone Lysine Demethylases to Drive Transformation in IDH-Mutant Cancers. Cancer Discov. 2023 06 02; 13(6):1478-1497.
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Transmission of stimulus-induced epigenetic changes through cell division is coupled to continuous transcription factor activity. Front Immunol. 2023; 14:1129577.
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PALI1 promotes tumor growth through competitive recruitment of PRC2 to G9A-target chromatin for dual epigenetic silencing. Mol Cell. 2022 12 15; 82(24):4611-4626.e7.
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The landscape of Chlamydomonas histone H3 lysine 4 methylation reveals both constant features and dynamic changes during the diurnal cycle. Plant J. 2022 10; 112(2):352-368.
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Therapeutic Targeting of EZH2 and BET BRD4 in Pediatric Rhabdoid Tumors. Mol Cancer Ther. 2022 05 04; 21(5):715-726.