Lymphotoxin beta Receptor
"Lymphotoxin beta Receptor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the tumor necrosis factor receptor superfamily. It has specificity for LYMPHOTOXIN ALPHA1, BETA2 HETEROTRIMER and TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14. The receptor plays a role in regulating lymphoid ORGANOGENESIS and the differentiation of certain subsets of NATURAL KILLER T-CELLS. Signaling of the receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
| Descriptor ID |
D053259
|
| MeSH Number(s) |
D12.776.543.750.705.852.760.245
|
| Concept/Terms |
Lymphotoxin beta Receptor- Lymphotoxin beta Receptor
- Receptor, Lymphotoxin beta
- beta Receptor, Lymphotoxin
- TNFR Superfamily, Member 3
- Tumor Necrosis Factor Receptor Superfamily, Member 3
- Receptors, Lymphotoxin beta
- Lymphotoxin beta Receptors
- beta Receptors, Lymphotoxin
|
Below are MeSH descriptors whose meaning is more general than "Lymphotoxin beta Receptor".
Below are MeSH descriptors whose meaning is more specific than "Lymphotoxin beta Receptor".
This graph shows the total number of publications written about "Lymphotoxin beta Receptor" by people in this website by year, and whether "Lymphotoxin beta Receptor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 3 | 3 |
| 2003 | 0 | 3 | 3 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 2 | 2 |
| 2007 | 2 | 1 | 3 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2012 | 2 | 0 | 2 |
| 2013 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lymphotoxin beta Receptor" by people in Profiles.
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Clinical Efficacy and Safety of Baminercept, a Lymphotoxin ß Receptor Fusion Protein, in Primary Sjögren's Syndrome: Results From a Phase II Randomized, Double-Blind, Placebo-Controlled Trial. Arthritis Rheumatol. 2018 09; 70(9):1470-1480.
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Type 3 innate lymphoid cell-derived lymphotoxin prevents microbiota-dependent inflammation. Cell Mol Immunol. 2018 07; 15(7):697-709.
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Facilitating T Cell Infiltration in Tumor Microenvironment Overcomes Resistance to PD-L1 Blockade. Cancer Cell. 2016 Mar 14; 29(3):285-296.
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Lymphotoxin organizes contributions to host defense and metabolic illness from innate lymphoid cells. Cytokine Growth Factor Rev. 2014 Apr; 25(2):227-33.
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Lymphotoxin signalling in immune homeostasis and the control of microorganisms. Nat Rev Immunol. 2013 Apr; 13(4):270-9.
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LIGHT/TNFSR14 can regulate hepatic lipase expression by hepatocytes independent of T cells and Kupffer cells. PLoS One. 2013; 8(1):e54719.
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Securing the border: lymphotoxin, IL-23 and IL-22 keep out the bad guys and 'fatten' the homeland. Nat Immunol. 2012 Oct; 13(10):940-1.
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Lymphotoxin regulates commensal responses to enable diet-induced obesity. Nat Immunol. 2012 Oct; 13(10):947-53.
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Lymphotoxin controls the IL-22 protection pathway in gut innate lymphoid cells during mucosal pathogen challenge. Cell Host Microbe. 2011 Jul 21; 10(1):44-53.
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Parenteral nutrition impairs lymphotoxin ß receptor signaling via NF-?B. Ann Surg. 2011 May; 253(5):996-1003.