Glucocorticoid-Induced TNFR-Related Protein
"Glucocorticoid-Induced TNFR-Related Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the TNF receptor family that was initially identified as a DEXAMETHASONE-induced protein from a T-CELL line. It may play a role in regulating APOPTOSIS and modulating immune response by T-lymphocytes. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
| Descriptor ID |
D053450
|
| MeSH Number(s) |
D12.776.543.750.705.852.760.238
|
| Concept/Terms |
Glucocorticoid-Induced TNFR-Related Protein- Glucocorticoid-Induced TNFR-Related Protein
- Glucocorticoid Induced TNFR Related Protein
- TNFR-Related Protein, Glucocorticoid-Induced
- Receptors, Tumor Necrosis Factor, Member 18
- Tumor Necrosis Factor Receptor Superfamily, Member 18
- CD357 Antigen
- Antigen, CD357
|
Below are MeSH descriptors whose meaning is more general than "Glucocorticoid-Induced TNFR-Related Protein".
Below are MeSH descriptors whose meaning is more specific than "Glucocorticoid-Induced TNFR-Related Protein".
This graph shows the total number of publications written about "Glucocorticoid-Induced TNFR-Related Protein" by people in this website by year, and whether "Glucocorticoid-Induced TNFR-Related Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Glucocorticoid-Induced TNFR-Related Protein" by people in Profiles.
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First-in-human phase I/Ib open-label dose-escalation study of GWN323 (anti-GITR) as a single agent and in combination with spartalizumab (anti-PD-1) in patients with advanced solid tumors and lymphomas. J Immunother Cancer. 2021 08; 9(8).
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PD-1 upregulated on regulatory T cells during chronic virus infection enhances the suppression of CD8+ T cell immune response via the interaction with PD-L1 expressed on CD8+ T cells. J Immunol. 2015 Jun 15; 194(12):5801-11.
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Glucocorticoid-induced TNFR-related protein stimulation reverses cardiac allograft acceptance induced by CD40-CD40L blockade. Clin Dev Immunol. 2013; 2013:986859.
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IDO expression in brain tumors increases the recruitment of regulatory T cells and negatively impacts survival. Clin Cancer Res. 2012 Nov 15; 18(22):6110-21.
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Induction of regulatory T cell-resistant helper CD4+ T cells by bacterial vector. Blood. 2008 Feb 01; 111(3):1404-12.