"fas Receptor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tumor necrosis factor receptor subtype found in a variety of tissues and on activated LYMPHOCYTES. It has specificity for FAS LIGAND and plays a role in regulation of peripheral immune responses and APOPTOSIS. Multiple isoforms of the protein exist due to multiple ALTERNATIVE SPLICING. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM. Mutations in the CD95 gene are associated with cases of autoimmune lymphoproliferative syndrome.
| Descriptor ID |
D019014
|
| MeSH Number(s) |
D12.776.543.750.690.500 D12.776.543.750.705.852.760.195
|
| Concept/Terms |
fas Receptor- fas Receptor
- Receptor, fas
- fas Antigen
- fas Antigens
- APO-1 Antigen
- APO 1 Antigen
- CD95 Antigen
- TNFRSF6 Receptor
- Receptor, TNFRSF6
- Antigens, CD95
- Receptors, fas
- fas Receptors
- Tumor Necrosis Factor Receptor Superfamily, Member 6
- Fas Cell Surface Death Receptor
- CD95 Antigens
|
Below are MeSH descriptors whose meaning is more general than "fas Receptor".
Below are MeSH descriptors whose meaning is more specific than "fas Receptor".
This graph shows the total number of publications written about "fas Receptor" by people in this website by year, and whether "fas Receptor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 4 | 3 | 7 |
| 1999 | 0 | 3 | 3 |
| 2000 | 2 | 2 | 4 |
| 2001 | 2 | 5 | 7 |
| 2002 | 2 | 1 | 3 |
| 2003 | 5 | 2 | 7 |
| 2004 | 0 | 7 | 7 |
| 2005 | 0 | 2 | 2 |
| 2006 | 1 | 0 | 1 |
| 2007 | 2 | 1 | 3 |
| 2008 | 1 | 1 | 2 |
| 2009 | 2 | 0 | 2 |
| 2010 | 2 | 1 | 3 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 2 | 0 | 2 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 2 | 0 | 2 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "fas Receptor" by people in Profiles.
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Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis. Cell. 2021 06 10; 184(12):3163-3177.e21.
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Non-apoptotic Fas (CD95) Signaling on T Cells Regulates the Resolution of Th2-Mediated Inflammation. Front Immunol. 2018; 9:2521.
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Allergen Exposure in Lymphopenic Fas-Deficient Mice Results in Persistent Eosinophilia Due to Defects in Resolution of Inflammation. Front Immunol. 2018; 9:2395.
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CD95/Fas Increases Stemness in Cancer Cells by Inducing a STAT1-Dependent Type I Interferon Response. Cell Rep. 2017 03 07; 18(10):2373-2386.
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A High-Throughput Cell-Based Screen Identified a 2-[(E)-2-Phenylvinyl]-8-Quinolinol Core Structure That Activates p53. PLoS One. 2016; 11(4):e0154125.
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Fas-Activated Mitochondrial Apoptosis Culls Stalled Embryonic Stem Cells to Promote Differentiation. Curr Biol. 2015 Dec 07; 25(23):3110-8.
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Evaluation of circulating markers of hepatic apoptosis and inflammation in obese children with and without obstructive sleep apnea. Sleep Med. 2015 Sep; 16(9):1031-5.
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The role of CD95 and CD95 ligand in cancer. Cell Death Differ. 2015 Apr; 22(4):549-59.
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CD95 and CD95L promote and protect cancer stem cells. Nat Commun. 2014 Nov 04; 5:5238.
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Loss of the death receptor CD95 (Fas) expression by dendritic cells protects from a chronic viral infection. Proc Natl Acad Sci U S A. 2014 Jun 10; 111(23):8559-64.