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Douglas Kyle Hogarth

TitleProfessor
InstitutionUniversity of Chicago
DepartmentMedicine-Pulmonary/Critical Care
AddressChicago IL 60637
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    Collapse Overview 
    Collapse overview
    D. Kyle Hogarth, MD, FCCP, is a Professor of Medicine in the Section of Pulmonary and Critical Care Medicine at The University of Chicago. He is the Director of Bronchoscopy and is heavily involved in the field of advanced bronchoscopy and interventional pulmonary with numerous publications.
    Dr. Hogarth received his medical degree at Case Western Reserve University School of Medicine in Cleveland, Ohio. He then completed a residency in Internal Medicine and a fellowship in Pulmonary and Critical Care at The University of Chicago. He has been published in the New England Journal of Medicine, Chest, ERJ and many other journals. He serves on the editorial board of CHEST, where he is the section editor for the podcast section. He has won numerous clinical awards and teaching awards from his University. He is a founding member and the past President of the Society for Advanced Bronchoscopy.


    Collapse Biography 
    Collapse education and training
    Miami University, Oxford, OHBA05/1994Chemistry, Biology, and Microbiology (triple major)
    Case Western Reserve, Cleveland, OHMD05/1998Medicine
    University of Chicago, Chicago, IL06/2001internal Medicine
    University of Chicago, Chicago, IL12/2004Pulmonary and Critical Care

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Criner GJ, Delage A, Voelker K, Hogarth DK, Majid A, Zgoda M, Lazarus DR, Casal R, Benzaquen SB, Holladay RC, Wellikoff A, Calero K, Rumbak MJ, Branca PR, Abu-Hijleh M, Mallea JM, Kalhan R, Sachdeva A, Kinsey CM, Lamb CR, Reed MF, Abouzgheib WB, Kaplan PV, Marrujo GX, Johnstone DW, Gasparri MG, Meade AA, Hergott CA, Reddy C, Mularski RA, Case AH, Makani SS, Shepherd RW, Chen B, Holt GE, Martel S. Improving Lung Function in Severe Heterogenous Emphysema with the Spiration Valve System (EMPROVE). A Multicenter, Open-Label Randomized Controlled Clinical Trial. Am J Respir Crit Care Med. 2019 Dec 01; 200(11):1354-1362. PMID: 31365298.
      View in: PubMed
    2. Bermea RS, Miller J, Wilson WW, Dugan K, Frye L, Murgu S, Hogarth DK. One-Way Endobronchial Valves as Management for Persistent Air Leaks: A Preview of What's to Come? Am J Respir Crit Care Med. 2019 Nov 15; 200(10):1318-1320. PMID: 31310162.
      View in: PubMed
    3. Chaddha U, Hogarth DK, Murgu S. Bronchoscopic Ablative Therapies for Malignant Central Airway Obstruction and Peripheral Lung Tumors. Ann Am Thorac Soc. 2019 Oct; 16(10):1220-1229. PMID: 31194922.
      View in: PubMed
    4. Abu-Hijleh M, Styrvoky K, Anand V, Woll F, Yarmus L, Machuzak MS, Nader DA, Mullett TW, Hogarth DK, Toth JW, Acash G, Casal RF, Hazelrigg S, Wood DE. Intrabronchial Valves for Air Leaks After Lobectomy, Segmentectomy, and Lung Volume Reduction Surgery. Lung. 2019 10; 197(5):627-633. PMID: 31463549.
      View in: PubMed
    5. Chaddha U, Hogarth DK, Murgu S. The role of endobronchial ultrasound transbronchial needle aspiration for programmed death ligand 1 testing and next generation sequencing in advanced non-small cell lung cancer. Ann Transl Med. 2019 Aug; 7(15):351. PMID: 31516897.
      View in: PubMed
    6. Sharma A, Laxman B, Naureckas ET, Hogarth DK, Sperling AI, Solway J, Ober C, Gilbert JA, White SR. Associations between fungal and bacterial microbiota of airways and asthma endotypes. J Allergy Clin Immunol. 2019 Nov; 144(5):1214-1227.e7. PMID: 31279011.
      View in: PubMed
    7. Chaddha U, Hogarth DK, Murgu S. Perspective on airway stenting in inoperable patients with tracheoesophageal fistula after curative-intent treatment for esophageal cancer. J Thorac Dis. 2019 May; 11(5):2165-2174. PMID: 31285911.
      View in: PubMed
    8. White SR, Laxman B, Naureckas ET, Hogarth DK, Solway J, Sperling AI, Ober C. Evidence for an IL-6-high asthma phenotype in asthmatic patients of African ancestry. J Allergy Clin Immunol. 2019 Jul; 144(1):304-306.e4. PMID: 31029772.
      View in: PubMed
    9. Newell JA, Donahue C, Hogarth DK. An NP's guide to diagnosing and treating alpha-1 antitrypsin deficiency. Nurse Pract. 2019 Apr; 44(4):13-21. PMID: 30829939.
      View in: PubMed
    10. Hogarth DK, Mahajan AK. The Society for Advanced Bronchoscopy: An Introduction. Chest. 2019 Jun; 155(6):1092-1094. PMID: 30825444.
      View in: PubMed
    11. Chaddha U, Kurman JS, Mahajan A, Hogarth DK. Lung Nodule Management: An Interventional Pulmonology Perspective. Semin Respir Crit Care Med. 2018 Dec; 39(6):661-666. PMID: 30641583.
      View in: PubMed
    12. Folch EE, Pritchett MA, Nead MA, Bowling MR, Murgu SD, Krimsky WS, Murillo BA, LeMense GP, Minnich DJ, Bansal S, Ellis BQ, Mahajan AK, Gildea TR, Bechara RI, Sztejman E, Flandes J, Rickman OB, Benzaquen S, Hogarth DK, Linden PA, Wahidi MM, Mattingley JS, Hood KL, Lin H, Wolvers JJ, Khandhar SJ. Electromagnetic Navigation Bronchoscopy for Peripheral Pulmonary Lesions: One-Year Results of the Prospective, Multicenter NAVIGATE Study. J Thorac Oncol. 2019 03; 14(3):445-458. PMID: 30476574.
      View in: PubMed
    13. Han X, Zhang S, Zhao W, Wei D, Wang Y, Hogarth DK, Liu X. A successful bronchial thermoplasty procedure in a "very severe" asthma patient with rare complications: a case report. J Asthma. 2019 Sep; 56(9):1004-1007. PMID: 30285511.
      View in: PubMed
    14. Tan LD, Yoneda KY, Louie S, Hogarth DK, Castro M. Bronchial Thermoplasty: A Decade of Experience: State of the Art. J Allergy Clin Immunol Pract. 2019 01; 7(1):71-80. PMID: 30193939.
      View in: PubMed
    15. Hogarth DK. Use of augmented fluoroscopic imaging during diagnostic bronchoscopy. Future Oncol. 2018 Sep; 14(22):2247-2252. PMID: 29661040.
      View in: PubMed
    16. Morris S, Vachani A, Pass HI, Rom WN, Ryden K, Weiss GJ, Hogarth DK, Runger G, Richards D, Shelton T, Mallery DW. Whole blood FPR1 mRNA expression predicts both non-small cell and small cell lung cancer. Int J Cancer. 2018 06 01; 142(11):2355-2362. PMID: 29313979.
      View in: PubMed
    17. Akthar AS, Koshy M, Ferguson MK, Murgu S, Hogarth DK, Golden DW, Connell PP, Davies EM, Kowalski E, Malik R. Effect of Endoscopic Bronchial Ultrasound on Outcomes for Stage I Non-Small-Cell Lung Cancer Patients Receiving Hypofractionated Radiotherapy. Clin Lung Cancer. 2018 03; 19(2):e227-e233. PMID: 28939097.
      View in: PubMed
    18. Dugan KC, Laxmanan B, Murgu S, Hogarth DK. Response. Chest. 2017 08; 152(2):450. PMID: 28797392.
      View in: PubMed
    19. Gildea TR, DaCosta Byfield S, Hogarth DK, Wilson DS, Quinn CC. A retrospective analysis of delays in the diagnosis of lung cancer and associated costs. Clinicoecon Outcomes Res. 2017; 9:261-269. PMID: 28553128.
      View in: PubMed
    20. White SR, Nicodemus-Johnson J, Laxman B, Denner DR, Naureckas ET, Hogarth DK, Stern R, Minc A, Solway J, Sperling A, Ober C. Elevated levels of soluble humanleukocyte antigen-G in the airways are a marker for a low-inflammatory endotype of asthma. J Allergy Clin Immunol. 2017 09; 140(3):857-860. PMID: 28363527.
      View in: PubMed
    21. Dugan KC, Laxmanan B, Murgu S, Hogarth DK. Management of Persistent Air Leaks. Chest. 2017 08; 152(2):417-423. PMID: 28267436.
      View in: PubMed
    22. Mullon JJ, Burkart KM, Silvestri G, Hogarth DK, Almeida F, Berkowitz D, Eapen GA, Feller-Kopman D, Fessler HE, Folch E, Gillespie C, Haas A, Islam SU, Lamb C, Levine SM, Majid A, Maldonado F, Musani AI, Piquette C, Ray C, Reddy CB, Rickman O, Simoff M, Wahidi MM, Lee H. Interventional Pulmonology Fellowship Accreditation Standards: Executive Summary of the Multisociety Interventional Pulmonology Fellowship Accreditation Committee. Chest. 2017 05; 151(5):1114-1121. PMID: 28132754.
      View in: PubMed
    23. Nicodemus-Johnson J, Myers RA, Sakabe NJ, Sobreira DR, Hogarth DK, Naureckas ET, Sperling AI, Solway J, White SR, Nobrega MA, Nicolae DL, Gilad Y, Ober C. DNA methylation in lung cells is associated with asthma endotypes and genetic risk. JCI Insight. 2016 12 08; 1(20):e90151. PMID: 27942592.
      View in: PubMed
    24. Murtagh G, Laffin LJ, Patel KV, Patel AV, Bonham CA, Yu Z, Addetia K, El-Hangouche N, Maffesanti F, Mor-Avi V, Hogarth DK, Sweiss NJ, Beshai JF, Lang RM, Patel AR. Improved detection of myocardial damage in sarcoidosis using longitudinal strain in patients with preserved left ventricular ejection fraction. Echocardiography. 2016 Sep; 33(9):1344-52. PMID: 27677642.
      View in: PubMed
    25. Micic D, Hogarth DK, Kavitt RT. Mediastinal granuloma: a rare cause of dysphagia. BMJ Case Rep. 2016 Jun 14; 2016. PMID: 27302638.
      View in: PubMed
    26. Sandhaus RA, Turino G, Brantly ML, Campos M, Cross CE, Goodman K, Hogarth DK, Knight SL, Stocks JM, Stoller JK, Strange C, Teckman J. The Diagnosis and Management of Alpha-1 Antitrypsin Deficiency in the Adult. Chronic Obstr Pulm Dis. 2016 06 06; 3(3):668-682. PMID: 28848891.
      View in: PubMed
    27. Vigneswaran J, Tan YH, Murgu SD, Won BM, Patton KA, Villaflor VM, Hoffman PC, Hensing T, Hogarth DK, Malik R, MacMahon H, Mueller J, Simon CA, Vigneswaran WT, Wigfield CH, Ferguson MK, Husain AN, Vokes EE, Salgia R. Comprehensive genetic testing identifies targetable genomic alterations in most patients with non-small cell lung cancer, specifically adenocarcinoma, single institute investigation. Oncotarget. 2016 Apr 05; 7(14):18876-86. PMID: 26934441.
      View in: PubMed
    28. Laxmanan B, Egressy K, Murgu SD, White SR, Hogarth DK. Advances in Bronchial Thermoplasty. Chest. 2016 09; 150(3):694-704. PMID: 27006157.
      View in: PubMed
    29. Murgu SD, Egressy K, Laxmanan B, Doblare G, Ortiz-Comino R, Hogarth DK. Central Airway Obstruction: Benign Strictures, Tracheobronchomalacia, and Malignancy-related Obstruction. Chest. 2016 08; 150(2):426-41. PMID: 26874192.
      View in: PubMed
    30. Patel MB, Mor-Avi V, Murtagh G, Bonham CA, Laffin LJ, Hogarth DK, Medvedofsky D, Lang RM, Patel AR. Right Heart Involvement in Patients with Sarcoidosis. Echocardiography. 2016 May; 33(5):734-41. PMID: 26773449.
      View in: PubMed
    31. Murtagh G, Laffin LJ, Beshai JF, Maffessanti F, Bonham CA, Patel AV, Yu Z, Addetia K, Mor-Avi V, Moss JD, Hogarth DK, Sweiss NJ, Lang RM, Patel AR. Prognosis of Myocardial Damage in Sarcoidosis Patients With Preserved Left Ventricular Ejection Fraction: Risk Stratification Using Cardiovascular Magnetic Resonance. Circ Cardiovasc Imaging. 2016 Jan; 9(1):e003738. PMID: 26763280.
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    32. Denner DR, Sangwan N, Becker JB, Hogarth DK, Oldham J, Castillo J, Sperling AI, Solway J, Naureckas ET, Gilbert JA, White SR. Corticosteroid therapy and airflow obstruction influence the bronchial microbiome, which is distinct from that of bronchoalveolar lavage in asthmatic airways. J Allergy Clin Immunol. 2016 05; 137(5):1398-1405.e3. PMID: 26627545.
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    33. Huang Y, Ma SF, Vij R, Oldham JM, Herazo-Maya J, Broderick SM, Strek ME, White SR, Hogarth DK, Sandbo NK, Lussier YA, Gibson KF, Kaminski N, Garcia JG, Noth I. A functional genomic model for predicting prognosis in idiopathic pulmonary fibrosis. BMC Pulm Med. 2015 Nov 21; 15:147. PMID: 26589497.
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    34. Riazanski V, Gabdoulkhakova AG, Boynton LS, Eguchi RR, Deriy LV, Hogarth DK, Loaƫc N, Oumata N, Galons H, Brown ME, Shevchenko P, Gallan AJ, Yoo SG, Naren AP, Villereal ML, Beacham DW, Bindokas VP, Birnbaumer L, Meijer L, Nelson DJ. TRPC6 channel translocation into phagosomal membrane augments phagosomal function. Proc Natl Acad Sci U S A. 2015 Nov 24; 112(47):E6486-95. PMID: 26604306.
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    35. Walkey AJ, Hogarth DK, Lip GYH. Optimizing atrial fibrillation management: from ICU and beyond. Chest. 2015 Oct; 148(4):859-864. PMID: 25951122.
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    36. Denner DR, Doeing DC, Hogarth DK, Dugan K, Naureckas ET, White SR. Airway Inflammation after Bronchial Thermoplasty for Severe Asthma. Ann Am Thorac Soc. 2015 Sep; 12(9):1302-9. PMID: 26230374.
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    37. Laxmanan B, Hogarth DK. Bronchial thermoplasty in asthma: current perspectives. J Asthma Allergy. 2015; 8:39-49. PMID: 26028976.
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    38. Come CE, Kramer MR, Dransfield MT, Abu-Hijleh M, Berkowitz D, Bezzi M, Bhatt SP, Boyd MB, Cases E, Chen AC, Cooper CB, Flandes J, Gildea T, Gotfried M, Hogarth DK, Kolandaivelu K, Leeds W, Liesching T, Marchetti N, Marquette C, Mularski RA, Pinto-Plata VM, Pritchett MA, Rafeq S, Rubio ER, Slebos DJ, Stratakos G, Sy A, Tsai LW, Wahidi M, Walsh J, Wells JM, Whitten PE, Yusen R, Zulueta JJ, Criner GJ, Washko GR. A randomised trial of lung sealant versus medical therapy for advanced emphysema. Eur Respir J. 2015 Sep; 46(3):651-62. PMID: 25837041.
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    39. Sweiss NJ, Noth I, Mirsaeidi M, Zhang W, Naureckas ET, Hogarth DK, Strek M, Caligiuri P, Machado RF, Niewold TB, Garcia JG, Pangan AL, Baughman RP. Efficacy Results of a 52-week Trial of Adalimumab in the Treatment of Refractory Sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis. 2014 Apr 18; 31(1):46-54. PMID: 24751453.
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    40. Mahajan AK, Hogarth DK. Taking control of your digital library: how modern citation managers do more than just referencing. Chest. 2013 Dec; 144(6):1930-1933. PMID: 24297125.
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    41. Siri D, Farah H, Hogarth DK. Distinguishing alpha1-antitrypsin deficiency from asthma. Ann Allergy Asthma Immunol. 2013 Dec; 111(6):458-64. PMID: 24267358.
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    42. Irwin RS, Hogarth DK, Barnes PJ. Introducing a new series: Giants in chest medicine. Chest. 2013 Oct; 144(4):1087. PMID: 24081333.
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    43. Mahajan AK, Hogarth DK. Payer coverage for bronchial thermoplasty: shifting the traditional paradigm for refractory asthma therapy. Chest. 2013 Sep; 144(3):1051-1054. PMID: 24008956.
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    44. Doeing DC, Husain AN, Naureckas ET, White SR, Hogarth DK. Bronchial thermoplasty failure in severe persistent asthma: a case report. J Asthma. 2013 Sep; 50(7):799-801. PMID: 23651158.
      View in: PubMed
    45. Patterson KC, Huang F, Oldham JM, Bhardwaj N, Hogarth DK, Mokhlesi B. Excessive daytime sleepiness and obstructive sleep apnea in patients with sarcoidosis. Chest. 2013 Jun; 143(6):1562-1568. PMID: 23258454.
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    46. Gordon IO, Husain AN, Charbeneau J, Krishnan JA, Hogarth DK. Endobronchial biopsy: a guide for asthma therapy selection in the era of bronchial thermoplasty. J Asthma. 2013 Aug; 50(6):634-41. PMID: 23621125.
      View in: PubMed
    47. Nicodemus-Johnson J, Laxman B, Stern RK, Sudi J, Tierney CN, Norwick L, Hogarth DK, McConville JF, Naureckas ET, Sperling AI, Solway J, Krishnan JA, Nicolae DL, White SR, Ober C. Maternal asthma and microRNA regulation of soluble HLA-G in the airway. J Allergy Clin Immunol. 2013 Jun; 131(6):1496-503. PMID: 23534973.
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    48. Mahajan AK, Doeing DC, Hogarth DK. Isolation of persistent air leaks and placement of intrabronchial valves. J Thorac Cardiovasc Surg. 2013 Mar; 145(3):626-30. PMID: 23312104.
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    49. Khan AY, Berkowitz D, Krimsky WS, Hogarth DK, Parks C, Bechara R. Safety of pacemakers and defibrillators in electromagnetic navigation bronchoscopy. Chest. 2013 Jan; 143(1):75-81. PMID: 22922452.
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    50. Doeing DC, Mahajan AK, White SR, Naureckas ET, Krishnan JA, Hogarth DK. Safety and feasibility of bronchial thermoplasty in asthma patients with very severe fixed airflow obstruction: a case series. J Asthma. 2013 Mar; 50(2):215-8. PMID: 23252954.
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    51. Mahajan AK, Hogarth DK. Bronchial thermoplasty: therapeutic success in severe asthma associated with persistent airflow obstruction. J Asthma. 2012 Jun; 49(5):527-9. PMID: 22515527.
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    52. Rahaghi FF, Sandhaus RA, Brantly ML, Rouhani F, Campos MA, Strange C, Hogarth DK, Eden E, Stocks JM, Krowka MJ, Stoller JK. The prevalence of alpha-1 antitrypsin deficiency among patients found to have airflow obstruction. COPD. 2012 Aug; 9(4):352-8. PMID: 22506682.
      View in: PubMed
    53. Patel AR, Klein MR, Chandra S, Spencer KT, Decara JM, Lang RM, Burke MC, Garrity ER, Hogarth DK, Archer SL, Sweiss NJ, Beshai JF. Myocardial damage in patients with sarcoidosis and preserved left ventricular systolic function: an observational study. Eur J Heart Fail. 2011 Nov; 13(11):1231-7. PMID: 21810833.
      View in: PubMed
    54. Mahajan AK, Hogarth DK. Bronchial thermoplasty: a promising therapy, still in its infancy. Cleve Clin J Med. 2011 Jul; 78(7):475-6. PMID: 21724931.
      View in: PubMed
    55. Mahajan AK, Patel S, Hogarth DK, Wightman R. Electromagnetic navigational bronchoscopy: an effective and safe approach to diagnose peripheral lung lesions unreachable by conventional bronchoscopy in high-risk patients. J Bronchology Interv Pulmonol. 2011 Apr; 18(2):133-7. PMID: 23169081.
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    56. Young RP, Hopkins RJ, Smith M, Hogarth DK. Smoking cessation: the potential role of risk assessment tools as motivational triggers. Postgrad Med J. 2010 Jan; 86(1011):26-33; quiz 31-2. PMID: 20065338.
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    57. Frank KM, Hogarth DK, Miller JL, Mandal S, Mease PJ, Samulski RJ, Weisgerber GA, Hart J. Investigation of the cause of death in a gene-therapy trial. N Engl J Med. 2009 Jul 09; 361(2):161-9. PMID: 19587341.
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    58. Hogarth DK, Jacobson TA. Inhaled anticholinergics and the long-term treatment of chronic obstructive pulmonary disease: Weighing benefits and risks. Clin Cornerstone. 2009; 9(3):45-9. PMID: 19781515.
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    59. Hogarth DK, Rachelefsky G. Screening and familial testing of patients for alpha 1-antitrypsin deficiency. Chest. 2008 Apr; 133(4):981-8. PMID: 18398118.
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    60. Rachelefsky G, Hogarth DK. Issues in the diagnosis of alpha 1-antitrypsin deficiency. J Allergy Clin Immunol. 2008 Apr; 121(4):833-8. PMID: 18313128.
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    61. Maitland ML, Wilcox R, Hogarth DK, Desai AA, Caligiuri P, Abrahams C, Salgia R. Diffuse alveolar damage after a single dose of topotecan in a patient with pulmonary fibrosis and small cell lung cancer. Lung Cancer. 2006 Nov; 54(2):243-5. PMID: 16949700.
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    62. Sandbo N, Qin Y, Taurin S, Hogarth DK, Kreutz B, Dulin NO. Regulation of serum response factor-dependent gene expression by proteasome inhibitors. Mol Pharmacol. 2005 Mar; 67(3):789-97. PMID: 15550677.
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    63. Hogarth DK, Sandbo N, Taurin S, Kolenko V, Miano JM, Dulin NO. Dual role of PKA in phenotypic modulation of vascular smooth muscle cells by extracellular ATP. Am J Physiol Cell Physiol. 2004 Aug; 287(2):C449-56. PMID: 15238360.
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    64. Hogarth DK, Hall J. Management of sedation in mechanically ventilated patients. Curr Opin Crit Care. 2004 Feb; 10(1):40-6. PMID: 15166848.
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