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Shu-Yuan Xiao

TitleProfessor
InstitutionUniversity of Chicago
DepartmentPathology
AddressChicago IL 60637
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    Collapse Overview 
    Collapse overview
    Dr. Xiao is a surgical pathologist with a subspecialty focus in gastrointestinal pathology. His diagnostic expertise includes neoplastic and non-neoplastic diseases of the gastrointestinal tract, liver, and biliary tract, and pancreas.


    Collapse Biography 
    Collapse education and training
    University of Chicago, ChicagoFellowship1999GI and Liver Pathology
    University of Chicago, ChicagoResidency1998Anatomic and Clinical Pathology
    National Institutes of Health, Bethesda, MDPostdoctoral fellowship 1990Neurological Disorders
    Hubei Medical University, WuhanMM1987Microbiology and Immunology
    Hubei Medical University, WuhanBM1984Medicine

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Cai L, Chen Y, Xiao SY. Clinicopathologic Features of Chronic Intestinal Schistosomiasis and Its Distinction From Crohn Disease. Am J Surg Pathol. 2021 03 01; 45(3):430-438. PMID: 32991343.
      View in: PubMed
    2. Catenacci DVT, Moya S, Lomnicki S, Chase LM, Peterson BF, Reizine N, Alpert L, Setia N, Xiao SY, Hart J, Siddiqui UD, Hogarth DK, Eng OS, Turaga K, Roggin K, Posner MC, Chang P, Narula S, Rampurwala M, Ji Y, Karrison T, Liao CY, Polite BN, Kindler HL. Personalized Antibodies for Gastroesophageal Adenocarcinoma (PANGEA): A Phase II Study Evaluating an Individualized Treatment Strategy for Metastatic Disease. Cancer Discov. 2021 Feb; 11(2):308-325. PMID: 33234578.
      View in: PubMed
    3. Yang C, Li Y, Xiao SY. Differential expression of ACE2 in the respiratory tracts and its relationship to COVID-19 pathogenesis. EBioMedicine. 2020 10; 60:103004. PMID: 32979833.
      View in: PubMed
    4. Zhao L, Xu L, Hemmerich A, Ferguson NL, Guy CD, McCall SJ, Cardona DM, Westerhoff M, Pai RK, Xiao SY, Liu B, Green CL, Hart J, Zhang X. Reduced MFAP5 expression in stroma of gallbladder adenocarcinoma and its potential diagnostic utility. Virchows Arch. 2021 Mar; 478(3):427-434. PMID: 32895766.
      View in: PubMed
    5. Wu Y, Guo W, Liu H, Qi B, Liang K, Xu H, Peng Z, Xiao SY. Clinical outcomes of 402 patients with COVID-2019 from a single center in Wuhan, China. J Med Virol. 2020 11; 92(11):2751-2757. PMID: 32530494.
      View in: PubMed
    6. Olivas AD, Setia N, Weber CR, Xiao SY, Villa E, Chapman CG, Siddiqui UD, Waxman I, Hart J, Alpert L. Histologic changes caused by injection of a novel submucosal lifting agent for endoscopic resection in GI lesions. Gastrointest Endosc. 2021 Feb; 93(2):470-476. PMID: 32593688.
      View in: PubMed
    7. Dingemans AC, Soo RA, Jazieh AR, Rice SJ, Kim YT, Teo LLS, Warren GW, Xiao SY, Smit EF, Aerts JG, Yoon SH, Veronesi G, De Cobelli F, Ramalingam SS, Garassino MC, Wynes MW, Behera M, Haanen J, Lu S, Peters S, Ahn MJ, Scagliotti GV, Adjei AA, Belani CP. Treatment Guidance for Patients With Lung Cancer During the Coronavirus 2019 Pandemic. J Thorac Oncol. 2020 07; 15(7):1119-1136. PMID: 32422364.
      View in: PubMed
    8. Li Y, Xiao SY. Hepatic involvement in COVID-19 patients: Pathology, pathogenesis, and clinical implications. J Med Virol. 2020 Sep; 92(9):1491-1494. PMID: 32369204.
      View in: PubMed
    9. Tian S, Xiao SY. Pathology of 2019 Novel Coronavirus Pneumonia: A Dynamic Disease Process. J Thorac Oncol. 2020 05; 15(5):e67-e68. PMID: 32340678.
      View in: PubMed
    10. Tian S, Liu H, Liao M, Wu Y, Yang C, Cai Y, Peng Z, Xiao SY. Analysis of Mortality in Patients With COVID-19: Clinical and Laboratory Parameters. Open Forum Infect Dis. 2020 May; 7(5):ofaa152. PMID: 32457924.
      View in: PubMed
    11. Tian S, Guo J, Tang X, Liu Y, Chen H, Cai Y, Xiao SY. Rare variants of solitary fibrous tumor. Pathol Res Pract. 2020 Jun; 216(6):152989. PMID: 32386774.
      View in: PubMed
    12. Tian S, Xiong Y, Liu H, Niu L, Guo J, Liao M, Xiao SY. Pathological study of the 2019 novel coronavirus disease (COVID-19) through postmortem core biopsies. Mod Pathol. 2020 06; 33(6):1007-1014. PMID: 32291399.
      View in: PubMed
    13. Tian S, Hu W, Niu L, Liu H, Xu H, Xiao SY. Pulmonary Pathology of Early-Phase 2019 Novel Coronavirus (COVID-19) Pneumonia in Two Patients With Lung Cancer. J Thorac Oncol. 2020 05; 15(5):700-704. PMID: 32114094.
      View in: PubMed
    14. Xiao SY, Wu Y, Liu H. Evolving status of the 2019 novel coronavirus infection: Proposal of conventional serologic assays for disease diagnosis and infection monitoring. J Med Virol. 2020 05; 92(5):464-467. PMID: 32031264.
      View in: PubMed
    15. Catenacci DVT, Chase L, Lomnicki S, Karrison T, de Wilton Marsh R, Rampurwala MM, Narula S, Alpert L, Setia N, Xiao SY, Hart J, Siddiqui UD, Peterson B, Moore K, Kipping-Johnson K, Markevicius U, Gordon B, Allen K, Racette C, Maron SB, Liao CY, Polite BN, Kindler HL, Turaga K, Prachand VN, Roggin KK, Ferguson MK, Posner MC. Evaluation of the Association of Perioperative UGT1A1 Genotype-Dosed gFOLFIRINOX With Margin-Negative Resection Rates and Pathologic Response Grades Among Patients With Locally Advanced Gastroesophageal Adenocarcinoma: A Phase 2 Clinical Trial. JAMA Netw Open. 2020 02 05; 3(2):e1921290. PMID: 32058557.
      View in: PubMed
    16. Tian S, Westbrook LM, Xiao SY, Zhang Y, Huang Y, Wang HL. The Morphologic Features of Primary Epstein-Barr Virus Infection in the Gastrointestinal Tract: An Approach to Correct Diagnosis. Am J Surg Pathol. 2019 09; 43(9):1253-1263. PMID: 31283632.
      View in: PubMed
    17. Zhao L, Westerhoff M, Hornick JL, Krausz T, Antic T, Xiao SY, Hart J. Loss of microfibril-associated protein 5 (MFAP5) expression in colon cancer stroma. Virchows Arch. 2020 Mar; 476(3):383-390. PMID: 31422503.
      View in: PubMed
    18. Yuan Q, Wu G, Xiao SY, Hou J, Ren Y, Wang H, Wang K, Zhang D. Identification and Preservation of Arm Lymphatic System in Axillary Dissection for Breast Cancer to Reduce Arm Lymphedema Events: A Randomized Clinical Trial. Ann Surg Oncol. 2019 Oct; 26(11):3446-3454. PMID: 31240591.
      View in: PubMed
    19. Yuan Q, Ren Y, Chen Q, Xiao SY, Wu G. Breast and axillary sparganosis: Migrating from axilla to breast. Breast J. 2019 09; 25(5):1006-1007. PMID: 31187547.
      View in: PubMed
    20. Alpert L, Yassan L, Poon R, Kadri S, Niu N, Patil SA, Mujacic I, Montes D, Galbo F, Wurst MN, Zhen CJ, Cohen RD, Rubin DT, Pekow JR, Weber CR, Xiao SY, Hart J, Segal J, Setia N. Targeted mutational analysis of inflammatory bowel disease-associated colorectal cancers. Hum Pathol. 2019 07; 89:44-50. PMID: 31054900.
      View in: PubMed
    21. Yuan Q, Wu G, Xiao SY, He Y, Wang K, Zhang D. Surgical Management of the Axilla in Breast Cancer Patients with Negative Sentinel Lymph Node: A Method to Reduce False-Negative Rate. World J Surg. 2019 Apr; 43(4):1047-1053. PMID: 30478688.
      View in: PubMed
    22. Li ZW, Sun B, Gong T, Guo S, Zhang J, Wang J, Sugawara A, Jiang M, Yan J, Gurary A, Zheng X, Gao B, Xiao SY, Chen W, Ma C, Farrar C, Zhu C, Chan OTM, Xin C, Winnicki A, Winnicki J, Tang M, Park R, Winnicki M, Diener K, Wang Z, Liu Q, Chu CH, Arter ZL, Yue P, Alpert L, Hui GS, Fei P, Turkson J, Yang W, Wu G, Tao A, Ramos JW, Moisyadi S, Holcombe RF, Jia W, Birnbaumer L, Zhou X, Chu WM. GNAI1 and GNAI3 Reduce Colitis-Associated Tumorigenesis in Mice by Blocking IL6 Signaling and Down-regulating Expression of GNAI2. Gastroenterology. 2019 06; 156(8):2297-2312. PMID: 30836096.
      View in: PubMed
    23. Tian S, Xiao SY, Chen Q, Liu H, Ping J. Monomorphic epitheliotropic intestinal T-cell lymphoma may mimic intestinal inflammatory disorders. Int J Immunopathol Pharmacol. 2019 Jan-Dec; 33:2058738419829387. PMID: 30757928.
      View in: PubMed
    24. Chen Q, Wang M, Wang M, Jin S, Xiao SY, Tian S. Expansile invasive growth pattern is definite evidence for the diagnosis of small hepatocellular carcinomas: a comparative study of 37 cases. Hum Pathol. 2018 10; 80:130-137. PMID: 29936057.
      View in: PubMed
    25. Wu XR, Liu HS, Shi XY, Zhou WX, Jiang ZN, Huang Y, Karamchandani DM, Goldblum JR, Xiao SY, Zhu HF, Feely MM, Collinsworth AL, Esnakula A, Xie H, Shen B, Lan P, Liu XL. Interobserver Agreement in the Diagnosis of Inflammatory Bowel Disease-Associated Neoplasia in China in Comparison to Subspecialized American Gastrointestinal Pathologists. Gastroenterol Res Pract. 2018; 2018:8715263. PMID: 29849600.
      View in: PubMed
    26. Foster CC, Lee AY, Furtado LV, Hart J, Alpert L, Xiao SY, Hyman NH, Sharma MR, Liauw SL. Treatment outcomes and HPV characteristics for an institutional cohort of patients with anal cancer receiving concurrent chemotherapy and intensity-modulated radiation therapy. PLoS One. 2018; 13(3):e0194234. PMID: 29522569.
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    27. Maron SB, Alpert L, Kwak HA, Lomnicki S, Chase L, Xu D, O'Day E, Nagy RJ, Lanman RB, Cecchi F, Hembrough T, Schrock A, Hart J, Xiao SY, Setia N, Catenacci DVT. Targeted Therapies for Targeted Populations: Anti-EGFR Treatment for EGFR-Amplified Gastroesophageal Adenocarcinoma. Cancer Discov. 2018 06; 8(6):696-713. PMID: 29449271.
      View in: PubMed
    28. Alpert L, Pai RK, Srivastava A, McKinnon W, Wilcox R, Yantiss RK, Arcega R, Wang HL, Robert ME, Liu X, Pai RK, Zhao L, Westerhoff M, Hampel H, Kupfer S, Setia N, Xiao SY, Hart J, Frankel WL. Colorectal Carcinomas With Isolated Loss of PMS2 Staining by Immunohistochemistry. Arch Pathol Lab Med. 2018 Apr; 142(4):523-528. PMID: 29336605.
      View in: PubMed
    29. Stier MW, Chapman CG, Kreitman A, Hart JA, Xiao SY, Siddiqui UD, Waxman I. Dissection-enabled scaffold-assisted resection (DeSCAR): a novel technique for resection of residual or non-lifting GI neoplasia of the colon (with video). Gastrointest Endosc. 2018 Mar; 87(3):843-851. PMID: 29158178.
      View in: PubMed
    30. Pectasides E, Stachler MD, Derks S, Liu Y, Maron S, Islam M, Alpert L, Kwak H, Kindler H, Polite B, Sharma MR, Allen K, O'Day E, Lomnicki S, Maranto M, Kanteti R, Fitzpatrick C, Weber C, Setia N, Xiao SY, Hart J, Nagy RJ, Kim KM, Choi MG, Min BH, Nason KS, O'Keefe L, Watanabe M, Baba H, Lanman R, Agoston AT, Oh DJ, Dunford A, Thorner AR, Ducar MD, Wollison BM, Coleman HA, Ji Y, Posner MC, Roggin K, Turaga K, Chang P, Hogarth K, Siddiqui U, Gelrud A, Ha G, Freeman SS, Rhoades J, Reed S, Gydush G, Rotem D, Davison J, Imamura Y, Adalsteinsson V, Lee J, Bass AJ, Catenacci DV. Genomic Heterogeneity as a Barrier to Precision Medicine in Gastroesophageal Adenocarcinoma. Cancer Discov. 2018 01; 8(1):37-48. PMID: 28978556.
      View in: PubMed
    31. Gupta N, Siddiqui U, Waxman I, Chapman C, Koons A, Valuckaite V, Xiao SY, Setia N, Hart J, Konda V. Use of volumetric laser endomicroscopy for dysplasia detection at the gastroesophageal junction and gastric cardia. World J Gastrointest Endosc. 2017 Jul 16; 9(7):319-326. PMID: 28744344.
      View in: PubMed
    32. Kwak HA, Liu X, Allende DS, Pai RK, Hart J, Xiao SY. Interobserver variability in intraductal papillary mucinous neoplasm subtypes and application of their mucin immunoprofiles. Mod Pathol. 2016 09; 29(9):977-84. PMID: 27198568.
      View in: PubMed
    33. Singh A, Siddiqui UD, Konda VJ, Whitcomb E, Hart J, Xiao SY, Ruiz MG, Koons A, Waxman I. Safety and efficacy of EMR for sporadic, nonampullary duodenal adenomas: a single U.S. center experience (with video). Gastrointest Endosc. 2016 Oct; 84(4):700-8. PMID: 27063918.
      View in: PubMed
    34. Catenacci DVT, Liao WL, Zhao L, Whitcomb E, Henderson L, O'Day E, Xu P, Thyparambil S, Krizman D, Bengali K, Uzzell J, Darfler M, Cecchi F, Blackler A, Bang YJ, Hart J, Xiao SY, Lee SM, Burrows J, Hembrough T. Mass-spectrometry-based quantitation of Her2 in gastroesophageal tumor tissue: comparison to IHC and FISH. Gastric Cancer. 2016 Oct; 19(4):1066-1079. PMID: 26581548.
      View in: PubMed
    35. Liu X, Chen D, Dugum M, Horvath B, Yuan L, Xiao SY. Syndromic and sporadic inflammatory/hyperplastic small-bowel polyps: a comparative study. Gastroenterol Rep (Oxf). 2015 Aug; 3(3):222-7. PMID: 26049720.
      View in: PubMed
    36. Li RF, Feng YQ, Chen JH, Ge LT, Xiao SY, Zuo XL. Naringenin suppresses K562 human leukemia cell proliferation and ameliorates Adriamycin-induced oxidative damage in polymorphonuclear leukocytes. Exp Ther Med. 2015 Mar; 9(3):697-706. PMID: 25667616.
      View in: PubMed
    37. Zhao L, Hart J, Xiao SY, Antic T. Cytological features of pancreatic intraductal tubulopapillary neoplasm and an unexpected immunohistochemical profile. Pathology. 2014 Dec; 46(7):662-5. PMID: 25393265.
      View in: PubMed
    38. Singh A, Konda VJ, Siddiqui U, Xiao SY, Waxman I. Use of narrow-band imaging with magnification to predict depth of invasion of early esophageal squamous cell cancer and to guide endoscopic therapy. Gastrointest Endosc. 2015 Feb; 81(2):469-70; discussion 470. PMID: 25450607.
      View in: PubMed
    39. Konda VJ, Koons A, Siddiqui UD, Xiao SY, Turner JR, Waxman I. Optical biopsy approaches in Barrett's esophagus with next-generation optical coherence tomography. Gastrointest Endosc. 2014 Sep; 80(3):516-7. PMID: 25127947.
      View in: PubMed
    40. Catenacci DV, Liao WL, Thyparambil S, Henderson L, Xu P, Zhao L, Rambo B, Hart J, Xiao SY, Bengali K, Uzzell J, Darfler M, Krizman DB, Cecchi F, Bottaro DP, Karrison T, Veenstra TD, Hembrough T, Burrows J. Absolute quantitation of Met using mass spectrometry for clinical application: assay precision, stability, and correlation with MET gene amplification in FFPE tumor tissue. PLoS One. 2014; 9(7):e100586. PMID: 24983965.
      View in: PubMed
    41. DeRoche TC, Xiao SY, Liu X. Histological evaluation in ulcerative colitis. Gastroenterol Rep (Oxf). 2014 Aug; 2(3):178-92. PMID: 24942757.
      View in: PubMed
    42. Konda VJ, Gonzalez Haba Ruiz M, Koons A, Hart J, Xiao SY, Siddiqui UD, Ferguson MK, Posner M, Patti MG, Waxman I. Complete endoscopic mucosal resection is effective and durable treatment for Barrett's-associated neoplasia. Clin Gastroenterol Hepatol. 2014 Dec; 12(12):2002-10.e1-2. PMID: 24732285.
      View in: PubMed
    43. Petersen JR, Stevenson HL, Kasturi KS, Naniwadekar A, Parkes J, Cross R, Rosenberg WM, Xiao SY, Snyder N. Evaluation of the aspartate aminotransferase/platelet ratio index and enhanced liver fibrosis tests to detect significant fibrosis due to chronic hepatitis C. J Clin Gastroenterol. 2014 Apr; 48(4):370-6. PMID: 24045284.
      View in: PubMed
    44. Zhang X, Liu X, Joseph L, Zhao L, Hart J, Xiao SY. Pancreatic ductal adenocarcinoma with autoimmune pancreatitis-like histologic and immunohistochemical features. Hum Pathol. 2014 Mar; 45(3):621-7. PMID: 24457081.
      View in: PubMed
    45. Wen XD, Wang CZ, Yu C, Zhao L, Zhang Z, Matin A, Wang Y, Li P, Xiao SY, Du W, He TC, Yuan CS. Panax notoginseng attenuates experimental colitis in the azoxymethane/dextran sulfate sodium mouse model. Phytother Res. 2014 Jun; 28(6):892-8. PMID: 24142591.
      View in: PubMed
    46. Whitcomb E, Liu X, Xiao SY. Crohn enteritis-associated small bowel adenocarcinomas exhibit gastric differentiation. Hum Pathol. 2014 Feb; 45(2):359-67. PMID: 24331840.
      View in: PubMed
    47. Chan OT, Chiles L, Levy M, Zhai J, Yerian LM, Xu H, Xiao SY, Soffer EE, Conklin JL, Dhall D, Kahn ME, Balzer BL, Amin MB, Wang HL. Smoothelin expression in the gastrointestinal tract: implication in colonic inertia. Appl Immunohistochem Mol Morphol. 2013 Oct; 21(5):452-9. PMID: 23060305.
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    48. Xie H, Xiao SY, Pai R, Jiang W, Shadrach B, Carver P, Wang Y, Shen B, Zhou W, Liu X. Diagnostic utility of TP53 and cytokeratin 7 immunohistochemistry in idiopathic inflammatory bowel disease-associated neoplasia. Mod Pathol. 2014 Feb; 27(2):303-13. PMID: 23887291.
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    49. Xiao SY, Zhao L, Hart J, Semrad CE. Gastric mucosal necrosis with vascular degeneration induced by doxycycline. Am J Surg Pathol. 2013 Feb; 37(2):259-63. PMID: 23060354.
      View in: PubMed
    50. Adams AP, Travassos da Rosa AP, Nunes MR, Xiao SY, Tesh RB. Pathogenesis of Modoc virus (Flaviviridae; Flavivirus) in persistently infected hamsters. Am J Trop Med Hyg. 2013 Mar; 88(3):455-60. PMID: 23358636.
      View in: PubMed
    51. Xiao SY. Intraductal papillary mucinous neoplasm of the pancreas: an update. Scientifica (Cairo). 2012; 2012:893632. PMID: 24278753.
      View in: PubMed
    52. Tretiakova M, Antic T, Westerhoff M, Mueller J, Himmelfarb EA, Wang HL, Xiao SY. Diagnostic utility of CD10 in benign and malignant extrahepatic bile duct lesions. Am J Surg Pathol. 2012 Jan; 36(1):101-8. PMID: 21989348.
      View in: PubMed
    53. Catenacci DV, Henderson L, Xiao SY, Patel P, Yauch RL, Hegde P, Zha J, Pandita A, Peterson A, Salgia R. Durable complete response of metastatic gastric cancer with anti-Met therapy followed by resistance at recurrence. Cancer Discov. 2011 Dec; 1(7):573-9. PMID: 22389872.
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    54. Chennat J, Konda VJ, Madrigal-Hoyos E, Fernandez-Sordo J, Xiao SY, Hart J, Waxman I. Biliary confocal laser endomicroscopy real-time detection of cholangiocarcinoma. Dig Dis Sci. 2011 Dec; 56(12):3701-6. PMID: 21695400.
      View in: PubMed
    55. Li M, Song J, Mirkov S, Xiao SY, Hart J, Liu W. Comparing morphometric, biochemical, and visual measurements of macrovesicular steatosis of liver. Hum Pathol. 2011 Mar; 42(3):356-60. PMID: 21111448.
      View in: PubMed
    56. Xiao SY. Mucinous Neoplasms of the Vermiform Appendix. Surg Pathol Clin. 2010 Jun; 3(2):395-409. PMID: 26839137.
      View in: PubMed
    57. Yan BC, Gong C, Song J, Krausz T, Tretiakova M, Hyjek E, Al-Ahmadie H, Alves V, Xiao SY, Anders RA, Hart JA. Arginase-1: a new immunohistochemical marker of hepatocytes and hepatocellular neoplasms. Am J Surg Pathol. 2010 Aug; 34(8):1147-54. PMID: 20661013.
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    58. Liang Y, Shilagard T, Xiao SY, Snyder N, Lau D, Cicalese L, Weiss H, Vargas G, Lemon SM. Visualizing hepatitis C virus infections in human liver by two-photon microscopy. Gastroenterology. 2009 Oct; 137(4):1448-58. PMID: 19632233.
      View in: PubMed
    59. Bhutani MS, Ahmed I, Verma D, Xiao SY, Brining D. An animal model for studying endoscopic ultrasound changes of early chronic pancreatitis with histologic correlation: a pilot study. Endoscopy. 2009 Apr; 41(4):352-6. PMID: 19340741.
      View in: PubMed
    60. Rychahou PG, Kang J, Gulhati P, Doan HQ, Chen LA, Xiao SY, Chung DH, Evers BM. Akt2 overexpression plays a critical role in the establishment of colorectal cancer metastasis. Proc Natl Acad Sci U S A. 2008 Dec 23; 105(51):20315-20. PMID: 19075230.
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    61. Siirin MT, Travassos da Rosa AP, Newman P, Weeks-Levy C, Coller BA, Xiao SY, Lieberman MM, Watts DM. Evaluation of the efficacy of a recombinant subunit West Nile vaccine in Syrian golden hamsters. Am J Trop Med Hyg. 2008 Dec; 79(6):955-62. PMID: 19052311.
      View in: PubMed
    62. Wu X, Lu L, Guzman H, Tesh RB, Xiao SY. Persistent infection and associated nucleotide changes of West Nile virus serially passaged in hamsters. J Gen Virol. 2008 Dec; 89(Pt 12):3073-3079. PMID: 19008395.
      View in: PubMed
    63. Snyder N, Martinez JG, Xiao SY. Chronic hepatitis C is a common associated with hepatic granulomas. World J Gastroenterol. 2008 Nov 07; 14(41):6366-9. PMID: 19009653.
      View in: PubMed
    64. Xu F, Liang X, Tesh RB, Xiao SY. Characterization of cell-death pathways in Punta Toro virus-induced hepatocyte injury. J Gen Virol. 2008 Sep; 89(Pt 9):2175-2181. PMID: 18753227.
      View in: PubMed
    65. Wang E, Volkova E, Adams AP, Forrester N, Xiao SY, Frolov I, Weaver SC. Chimeric alphavirus vaccine candidates for chikungunya. Vaccine. 2008 Sep 15; 26(39):5030-9. PMID: 18692107.
      View in: PubMed
    66. Ziegler SA, Lu L, da Rosa AP, Xiao SY, Tesh RB. An animal model for studying the pathogenesis of chikungunya virus infection. Am J Trop Med Hyg. 2008 Jul; 79(1):133-9. PMID: 18606777.
      View in: PubMed
    67. Gómez V, Xiao SY. Alendronate-induced esophagitis in an elderly woman. Int J Clin Exp Pathol. 2009; 2(2):200-3. PMID: 19079657.
      View in: PubMed
    68. Li G, Wang N, Guzman H, Sbrana E, Yoshikawa T, Tseng CT, Tesh RB, Xiao SY. Dhori virus (Orthomyxoviridae: Thogotovirus) infection of mice produces a disease and cytokine response pattern similar to that of highly virulent influenza A (H5N1) virus infection in humans. Am J Trop Med Hyg. 2008 Apr; 78(4):675-80. PMID: 18385368.
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    69. Xiao SY, Lu L, Wang HL. Fibrosing cholestatic hepatitis: clinicopathologic spectrum, diagnosis and pathogenesis. Int J Clin Exp Pathol. 2008 Jan 01; 1(5):396-402. PMID: 18787628.
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    70. Li G, Duan T, Wu X, Tesh RB, Soong L, Xiao SY. Yellow fever virus infection in Syrian golden hamsters: relationship between cytokine expression and pathologic changes. Int J Clin Exp Pathol. 2008 Jan 01; 1(2):169-79. PMID: 18784801.
      View in: PubMed
    71. Mateo RI, Xiao SY, Travassos da Rosa AP, Lei H, Guzman H, Lu L, Tesh RB. Yellow fever 17-D vaccine is neurotropic and produces encephalitis in immunosuppressed hamsters. Am J Trop Med Hyg. 2007 Nov; 77(5):919-24. PMID: 17984354.
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    72. Xu F, Chen H, Travassos da Rosa APA, Tesh RB, Xiao SY. Phylogenetic relationships among sandfly fever group viruses (Phlebovirus: Bunyaviridae) based on the small genome segment. J Gen Virol. 2007 Aug; 88(Pt 8):2312-2319. PMID: 17622637.
      View in: PubMed
    73. Xu F, Liu D, Nunes MR, DA Rosa AP, Tesh RB, Xiao SY. Antigenic and genetic relationships among Rift Valley fever virus and other selected members of the genus Phlebovirus (Bunyaviridae). Am J Trop Med Hyg. 2007 Jun; 76(6):1194-200. PMID: 17556635.
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    74. Mateo RI, Xiao SY, Lei H, DA Rosa AP, Tesh RB. Dhori virus (Orthomyxoviridae: Thogotovirus) infection in mice: a model of the pathogenesis of severe orthomyxovirus infection. Am J Trop Med Hyg. 2007 Apr; 76(4):785-90. PMID: 17426188.
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    75. Sbrana E, Jordan R, Hruby DE, Mateo RI, Xiao SY, Siirin M, Newman PC, DA Rosa AP, Tesh RB. Efficacy of the antipoxvirus compound ST-246 for treatment of severe orthopoxvirus infection. Am J Trop Med Hyg. 2007 Apr; 76(4):768-73. PMID: 17426185.
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    76. Snyder N, Nguyen A, Gajula L, Soloway R, Xiao SY, Lau DT, Petersen J. The APRI may be enhanced by the use of the FIBROSpect II in the estimation of fibrosis in chronic hepatitis C. Clin Chim Acta. 2007 Jun; 381(2):119-23. PMID: 17442291.
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    77. Raju GS, Shibukawa G, Ahmed I, Brining D, Poussard A, Xiao SY, Coe J, Cropper M, Martin D, Hull J. Endoluminal suturing may overcome the limitations of clip closure of a gaping wide colon perforation (with videos). Gastrointest Endosc. 2007 May; 65(6):906-11. PMID: 17350009.
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    78. Wu X, Zha D, Xiang G, Zhang B, Xiao SY, Jia R. Combined MMF and insulin therapy prevents renal injury in experimental diabetic rats. Cytokine. 2006 Dec; 36(5-6):229-36. PMID: 17337203.
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    79. Siirin MT, Duan T, Lei H, Guzman H, da Rosa AP, Watts DM, Xiao SY, Tesh RB. Chronic St. Louis encephalitis virus infection in the golden hamster (Mesocricetus auratus). Am J Trop Med Hyg. 2007 Feb; 76(2):299-306. PMID: 17297039.
      View in: PubMed
    80. Sbrana E, Xiao SY, Newman PC, Tesh RB. Comparative pathology of North American and central African strains of monkeypox virus in a ground squirrel model of the disease. Am J Trop Med Hyg. 2007 Jan; 76(1):155-64. PMID: 17255245.
      View in: PubMed
    81. Raju GS, Ahmed I, Xiao SY, Brining D, Poussard A, Tarcin O, Shibukawa G, Dawson K, Knight G, Tanguay R, Hull J. Controlled trial of immediate endoluminal closure of colon perforations in a porcine model by use of a novel clip device (with videos). Gastrointest Endosc. 2006 Dec; 64(6):989-97. PMID: 17140911.
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    82. Ge Y, Rampy BA, Wang HL, Xiao SY. Reduced CD1d expression in colonic epithelium in microscopic colitis. Appl Immunohistochem Mol Morphol. 2006 Sep; 14(3):309-13. PMID: 16932022.
      View in: PubMed
    83. Mateo R, Xiao SY, Guzman H, Lei H, Da Rosa AP, Tesh RB. Effects of immunosuppression on West Nile virus infection in hamsters. Am J Trop Med Hyg. 2006 Aug; 75(2):356-62. PMID: 16896148.
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    84. Snyder N, Gajula L, Xiao SY, Grady J, Luxon B, Lau DT, Soloway R, Petersen J. APRI: an easy and validated predictor of hepatic fibrosis in chronic hepatitis C. J Clin Gastroenterol. 2006 Jul; 40(6):535-42. PMID: 16825937.
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    85. Raju GS, Ahmed I, Brining D, Xiao SY. Endoluminal closure of large perforations of colon with clips in a porcine model (with video). Gastrointest Endosc. 2006 Oct; 64(4):640-6. PMID: 16996362.
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    86. Sbrana E, Mateo RI, Xiao SY, Popov VL, Newman PC, Tesh RB. Clinical laboratory, virologic, and pathologic changes in hamsters experimentally infected with Pirital virus (Arenaviridae): a rodent model of Lassa fever. Am J Trop Med Hyg. 2006 Jun; 74(6):1096-102. PMID: 16760527.
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    87. Sbrana E, Xiao SY, Popov VL, Newman PC, Tesh RB. Experimental yellow fever virus infection in the golden hamster (Mesocricetus auratus) III. Clinical laboratory values. Am J Trop Med Hyg. 2006 Jun; 74(6):1084-9. PMID: 16760525.
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    88. Raju GS, Gomez G, Xiao SY, Ahmed I, Brining D, Bhutani MS, Kalloo AN, Pasricha PJ. Effect of a novel pancreatic stent design on short-term pancreatic injury in a canine model. Endoscopy. 2006 Mar; 38(3):260-5. PMID: 16528653.
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    89. Moparty B, Xiao SY, Bhutani MS. Pyogenic granuloma presenting as a rectal polyp at the site of a previous polypectomy. Endoscopy. 2006; 38 Suppl 2:E2-3. PMID: 17366388.
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    90. Raju GS, Pham B, Xiao SY, Brining D, Ahmed I. A pilot study of endoscopic closure of colonic perforations with endoclips in a swine model. Gastrointest Endosc. 2005 Nov; 62(5):791-5. PMID: 16246701.
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    91. Ding X, Wu X, Duan T, Siirin M, Guzman H, Yang Z, Tesh RB, Xiao SY. Nucleotide and amino acid changes in West Nile virus strains exhibiting renal tropism in hamsters. Am J Trop Med Hyg. 2005 Oct; 73(4):803-7. PMID: 16222029.
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    92. Ding X, Xu F, Chen H, Tesh RB, Xiao SY. Apoptosis of hepatocytes caused by Punta Toro virus (Bunyaviridae: Phlebovirus) and its implication for Phlebovirus pathogenesis. Am J Pathol. 2005 Oct; 167(4):1043-9. PMID: 16192639.
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    93. Sunkureddi PR, Luu N, Xiao SY, Tang WW, Baethge BA. Eosinophilic enteritis with systemic lupus erythematosus. South Med J. 2005 Oct; 98(10):1049-52. PMID: 16295825.
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    94. Winston JH, He ZJ, Shenoy M, Xiao SY, Pasricha PJ. Molecular and behavioral changes in nociception in a novel rat model of chronic pancreatitis for the study of pain. Pain. 2005 Sep; 117(1-2):214-22. PMID: 16098667.
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    95. Lau DT, Luxon BA, Xiao SY, Beard MR, Lemon SM. Intrahepatic gene expression profiles and alpha-smooth muscle actin patterns in hepatitis C virus induced fibrosis. Hepatology. 2005 Aug; 42(2):273-81. PMID: 15986378.
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    96. Fillipowicz EA, Xiao Sy, Sower LE, Weems J, Payne DA. Detection of HCV in bile duct epithelium by laser capture microdissection (LCM). In Vivo. 2005 Jul-Aug; 19(4):737-9. PMID: 15999543.
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    97. Tesh RB, Siirin M, Guzman H, Travassos da Rosa AP, Wu X, Duan T, Lei H, Nunes MR, Xiao SY. Persistent West Nile virus infection in the golden hamster: studies on its mechanism and possible implications for other flavivirus infections. J Infect Dis. 2005 Jul 15; 192(2):287-95. PMID: 15962223.
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    98. Raju GS, Ahmed I, Xiao SY, Brining D, Bhutani MS, Pasricha PJ. Graded esophageal mucosal ablation with cryotherapy, and the protective effects of submucosal saline. Endoscopy. 2005 Jun; 37(6):523-6. PMID: 15933923.
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    99. McArthur MA, Xiao SY, Barrett AD. Phenotypic and molecular characterization of a non-lethal, hamster-viscerotropic strain of yellow fever virus. Virus Res. 2005 Jun; 110(1-2):65-71. PMID: 15845256.
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    100. Guzman H, Ding X, Xiao SY, Tesh RB. Duration of infectivity and RNA of Venezuelan equine encephalitis, West Nile, and yellow fever viruses dried on filter paper and maintained at room temperature. Am J Trop Med Hyg. 2005 Apr; 72(4):474-7. PMID: 15827290.
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    101. Xiao SY, Sbrana E, Watts DM, Siirin M, da Rosa AP, Tesh RB. Experimental infection of prairie dogs with monkeypox virus. Emerg Infect Dis. 2005 Apr; 11(4):539-45. PMID: 15829191.
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    102. Hoogerwerf WA, Gondesen K, Xiao SY, Winston JH, Willis WD, Pasricha PJ. The role of mast cells in the pathogenesis of pain in chronic pancreatitis. BMC Gastroenterol. 2005 Mar 03; 5:8. PMID: 15745445.
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    103. Tonry JH, Xiao SY, Siirin M, Chen H, da Rosa AP, Tesh RB. Persistent shedding of West Nile virus in urine of experimentally infected hamsters. Am J Trop Med Hyg. 2005 Mar; 72(3):320-4. PMID: 15772329.
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    104. Sbrana E, Tonry JH, Xiao SY, da Rosa AP, Higgs S, Tesh RB. Oral transmission of West Nile virus in a hamster model. Am J Trop Med Hyg. 2005 Mar; 72(3):325-9. PMID: 15772330.
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    105. Hoogerwerf WA, Shenoy M, Winston JH, Xiao SY, He Z, Pasricha PJ. Trypsin mediates nociception via the proteinase-activated receptor 2: a potentially novel role in pancreatic pain. Gastroenterology. 2004 Sep; 127(3):883-91. PMID: 15362043.
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    106. Sbrana E, Xiao SY, Guzman H, Ye M, Travassos da Rosa AP, Tesh RB. Efficacy of post-exposure treatment of yellow fever with ribavirin in a hamster model of the disease. Am J Trop Med Hyg. 2004 Sep; 71(3):306-12. PMID: 15381811.
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    107. Tesh RB, Watts DM, Sbrana E, Siirin M, Popov VL, Xiao SY. Experimental infection of ground squirrels (Spermophilus tridecemlineatus) with monkeypox virus. Emerg Infect Dis. 2004 Sep; 10(9):1563-7. PMID: 15498157.
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    108. Guo Y, Xiao SY, Yan H, Sun ND, Jiang MS, Liu DY. Cluster of acute hemorrhagic appendicitis among high school students in Wuhan, China. Am J Surg. 2004 Aug; 188(2):115-21. PMID: 15249235.
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    109. Morgan PB, Kessel IL, Xiao SY, Colman M. Uncommon presentations of Hodgkin's disease. Case 1. Hodgkin's disease of the jejunum. J Clin Oncol. 2004 Jan 01; 22(1):193-5. PMID: 14701782.
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    110. Fisher AF, Tesh RB, Tonry J, Guzman H, Liu D, Xiao SY. Induction of severe disease in hamsters by two sandfly fever group viruses, Punta toro and Gabek Forest (Phlebovirus, Bunyaviridae), similar to that caused by Rift Valley fever virus. Am J Trop Med Hyg. 2003 Sep; 69(3):269-76. PMID: 14628943.
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    111. Winston JH, Toma H, Shenoy M, He ZJ, Zou L, Xiao SY, Micci MA, Pasricha PJ. Acute pancreatitis results in referred mechanical hypersensitivity and neuropeptide up-regulation that can be suppressed by the protein kinase inhibitor k252a. J Pain. 2003 Aug; 4(6):329-37. PMID: 14622690.
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    112. He ZJ, Winston JH, Yusuf TE, Micci MA, Elfert A, Xiao SY, Pasricha PJ. Intraductal administration of an NK1 receptor antagonist attenuates the inflammatory response to retrograde infusion of radiological contrast in rats: implications for the pathogenesis and prevention of ERCP-induced pancreatitis. Pancreas. 2003 Jul; 27(1):e13-7. PMID: 12826913.
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    113. Xiao SY, Guzman H, da Rosa AP, Zhu HB, Tesh RB. Alteration of clinical outcome and histopathology of yellow fever virus infection in a hamster model by previous infection with heterologous flaviviruses. Am J Trop Med Hyg. 2003 Jun; 68(6):695-703. PMID: 12887029.
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    114. Campagnaro EL, Woodside KJ, Xiao SY, Daller JA, Evers BM. Cystosarcoma phyllodes (phyllodes tumor) of the male breast. Surgery. 2003 Jun; 133(6):689-91. PMID: 12796738.
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    115. Raja V, Lin JT, Xiao SY. Unusual abdominal tumors: case 2. Intra-abdominal desmoplastic small round cell tumor. J Clin Oncol. 2003 Mar 01; 21(5):951-3. PMID: 12610201.
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    116. Ge Y, Gatalica Z, Xiao SY. Pathologic quiz case: right thigh pain for 14 months. Arch Pathol Lab Med. 2003 Mar; 127(3):e171-2. PMID: 12653613.
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    117. Liu DY, Tesh RB, Travassos da Rosa APA, Peters CJ, Yang Z, Guzman H, Xiao SY. Phylogenetic relationships among members of the genus Phlebovirus (Bunyaviridae) based on partial M segment sequence analyses. J Gen Virol. 2003 Feb; 84(Pt 2):465-473. PMID: 12560581.
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    118. McArthur MA, Suderman MT, Mutebi JP, Xiao SY, Barrett AD. Molecular characterization of a hamster viscerotropic strain of yellow fever virus. J Virol. 2003 Jan; 77(2):1462-8. PMID: 12502861.
      View in: PubMed
    119. Tesh RB, Arroyo J, Travassos Da Rosa AP, Guzman H, Xiao SY, Monath TP. Efficacy of killed virus vaccine, live attenuated chimeric virus vaccine, and passive immunization for prevention of West Nile virus encephalitis in hamster model. Emerg Infect Dis. 2002 Dec; 8(12):1392-7. PMID: 12498653.
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    120. Tesh RB, Travassos da Rosa AP, Guzman H, Araujo TP, Xiao SY. Immunization with heterologous flaviviruses protective against fatal West Nile encephalitis. Emerg Infect Dis. 2002 Mar; 8(3):245-51. PMID: 11927020.
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    121. Lerat H, Honda M, Beard MR, Loesch K, Sun J, Yang Y, Okuda M, Gosert R, Xiao SY, Weinman SA, Lemon SM. Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus. Gastroenterology. 2002 Feb; 122(2):352-65. PMID: 11832450.
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    122. Syed S, Xiao SY, Schnadig VJ. Pathologic quiz case: adolescent girl presenting with solitary pulmonary nodule. Arch Pathol Lab Med. 2002 Feb; 126(2):227-8. PMID: 11825128.
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    123. Rampy BA, Waxman I, Xiao SY, Logroño R. Serous cystadenoma of the pancreas with papillary features: a diagnostic pitfall on fine-needle aspiration biopsy. Arch Pathol Lab Med. 2001 Dec; 125(12):1591-4. PMID: 11735697.
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    124. Hoogerwerf WA, Zou L, Shenoy M, Sun D, Micci MA, Lee-Hellmich H, Xiao SY, Winston JH, Pasricha PJ. The proteinase-activated receptor 2 is involved in nociception. J Neurosci. 2001 Nov 15; 21(22):9036-42. PMID: 11698614.
      View in: PubMed
    125. Xiao SY, Wang HL, Hart J, Fleming D, Beard MR. cDNA arrays and immunohistochemistry identification of CD10/CALLA expression in hepatocellular carcinoma. Am J Pathol. 2001 Oct; 159(4):1415-21. PMID: 11583969.
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    126. Xiao SY, Guzman H, Zhang H, Travassos da Rosa AP, Tesh RB. West Nile virus infection in the golden hamster (Mesocricetus auratus): a model for West Nile encephalitis. Emerg Infect Dis. 2001 Jul-Aug; 7(4):714-21. PMID: 11585537.
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    127. Xiao SY, Zhang H, Guzman H, Tesh RB. Experimental yellow fever virus infection in the Golden hamster (Mesocricetus auratus). II. Pathology. J Infect Dis. 2001 May 15; 183(10):1437-44. PMID: 11319680.
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    128. Tesh RB, Guzman H, da Rosa AP, Vasconcelos PF, Dias LB, Bunnell JE, Zhang H, Xiao SY. Experimental yellow fever virus infection in the Golden Hamster (Mesocricetus auratus). I. Virologic, biochemical, and immunologic studies. J Infect Dis. 2001 May 15; 183(10):1431-6. PMID: 11319679.
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    129. Xiao SY, Zhang H, Yang Y, Tesh RB. Pirital virus (Arenaviridae) infection in the syrian golden hamster, Mesocricetus auratus: a new animal model for arenaviral hemorrhagic fever. Am J Trop Med Hyg. 2001 Mar-Apr; 64(3-4):111-8. PMID: 11442204.
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    130. Boggino HE, Borkowski J, Xiao SY. Pathologic quiz case. Polypoid intranasal mass in 32-year-old woman. Arch Pathol Lab Med. 2001 Jan; 125(1):159-60. PMID: 11151074.
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    131. Xiao SY, Hart J. Marked gastric foveolar hyperplasia associated with active cytomegalovirus infection. Am J Gastroenterol. 2001 Jan; 96(1):223-6. PMID: 11197257.
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    132. Xiao SY, Rizzo P, Carbone M. Benign papillary mesothelioma of the tunica vaginalis testis. Arch Pathol Lab Med. 2000 Jan; 124(1):143-7. PMID: 10629148.
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