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Michael A. Becker

TitleEmeritus/Emerita, Professor
InstitutionUniversity of Chicago
DepartmentMedicine
AddressChicago IL 60637
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Hassoun H, Bayer R, Devlin S, Gentile T, Becker M, O'Dweyer K, Lesser M, Landau H, Chung D, Giralt S. A phase II clinical trial of lenalidomide intensification in patients with serologic/asymptomatic progression of multiple myeloma while on lenalidomide maintenance: a tri-state transplant consortium study. Leuk Lymphoma. 2020 Feb; 61(2):488-490. PMID: 31957517.
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    2. Jahn L, Kramann R, Marx N, Floege J, Becker M, Schlieper G. Speckle Tracking Echocardiography and All-Cause and Cardiovascular Mortality Risk in Chronic Kidney Disease Patients. Kidney Blood Press Res. 2019; 44(4):690-703. PMID: 31416075.
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    3. Courtright KR, Chivers C, Becker M, Regli SH, Pepper LC, Draugelis ME, O'Connor NR. Electronic Health Record Mortality Prediction Model for Targeted Palliative Care Among Hospitalized Medical Patients: a Pilot Quasi-experimental Study. J Gen Intern Med. 2019 Sep; 34(9):1841-1847. PMID: 31313110.
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    4. Rainò G, Becker MA, Bodnarchuk MI, Mahrt RF, Stöferle T, Kovalenko MV. Polymer and Colloid Highlights. Chimia (Aarau). 2019 Feb 27; 73(1):92. PMID: 30814009.
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    5. Saag KG, Becker MA, Whelton A, Hunt B, Castillo M, Kisfalvi K, Gunawardhana L. Efficacy and Safety of Febuxostat Extended and Immediate Release in Patients With Gout and Renal Impairment: A Phase III Placebo-Controlled Study. Arthritis Rheumatol. 2019 01; 71(1):143-153. PMID: 30073793.
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    6. Becker MA, Scarpelli L, Nedelcu G, Rainò G, Masia F, Borri P, Stöferle T, Kovalenko MV, Langbein W, Mahrt RF. Long Exciton Dephasing Time and Coherent Phonon Coupling in CsPbBr2Cl Perovskite Nanocrystals. Nano Lett. 2018 12 12; 18(12):7546-7551. PMID: 30407011.
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    7. Rainò G, Becker MA, Bodnarchuk MI, Mahrt RF, Kovalenko MV, Stöferle T. Superfluorescence from lead halide perovskite quantum dot superlattices. Nature. 2018 11; 563(7733):671-675. PMID: 30405237.
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    8. Gunawardhana L, Becker MA, Whelton A, Hunt B, Castillo M, Saag K. Efficacy and safety of febuxostat extended release and immediate release in patients with gout and moderate renal impairment: phase II placebo-controlled study. Arthritis Res Ther. 2018 05 30; 20(1):99. PMID: 29848361.
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    9. White WB, Saag KG, Becker MA, Borer JS, Gorelick PB, Whelton A, Hunt B, Castillo M, Gunawardhana L. Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout. N Engl J Med. 2018 Mar 29; 378(13):1200-1210. PMID: 29527974.
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    10. Becker MA, Vaxenburg R, Nedelcu G, Sercel PC, Shabaev A, Mehl MJ, Michopoulos JG, Lambrakos SG, Bernstein N, Lyons JL, Stöferle T, Mahrt RF, Kovalenko MV, Norris DJ, Rainò G, Efros AL. Bright triplet excitons in caesium lead halide perovskites. Nature. 2018 01 10; 553(7687):189-193. PMID: 29323292.
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    11. Herrick AL, Peytrignet S, Lunt M, Pan X, Hesselstrand R, Mouthon L, Silman AJ, Dinsdale G, Brown E, Czirják L, Distler JHW, Distler O, Fligelstone K, Gregory WJ, Ochiel R, Vonk MC, Ancuta C, Ong VH, Farge D, Hudson M, Matucci-Cerinic M, Balbir-Gurman A, Midtvedt Ø, Jobanputra P, Jordan AC, Stevens W, Moinzadeh P, Hall FC, Agard C, Anderson ME, Diot E, Madhok R, Akil M, Buch MH, Chung L, Damjanov NS, Gunawardena H, Lanyon P, Ahmad Y, Chakravarty K, Jacobsen S, MacGregor AJ, McHugh N, Müller-Ladner U, Riemekasten G, Becker M, Roddy J, Carreira PE, Fauchais AL, Hachulla E, Hamilton J, Inanç M, McLaren JS, van Laar JM, Pathare S, Proudman SM, Rudin A, Sahhar J, Coppere B, Serratrice C, Sheeran T, Veale DJ, Grange C, Trad GS, Denton CP. Patterns and predictors of skin score change in early diffuse systemic sclerosis from the European Scleroderma Observational Study. Ann Rheum Dis. 2018 04; 77(4):563-570. PMID: 29306872.
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    12. Herrick AL, Pan X, Peytrignet S, Lunt M, Hesselstrand R, Mouthon L, Silman A, Brown E, Czirják L, Distler JHW, Distler O, Fligelstone K, Gregory WJ, Ochiel R, Vonk M, Ancuta C, Ong VH, Farge D, Hudson M, Matucci-Cerinic M, Balbir-Gurman A, Midtvedt Ø, Jordan AC, Jobanputra P, Stevens W, Moinzadeh P, Hall FC, Agard C, Anderson ME, Diot E, Madhok R, Akil M, Buch MH, Chung L, Damjanov N, Gunawardena H, Lanyon P, Ahmad Y, Chakravarty K, Jacobsen S, MacGregor AJ, McHugh N, Müller-Ladner U, Riemekasten G, Becker M, Roddy J, Carreira PE, Fauchais AL, Hachulla E, Hamilton J, Inanç M, McLaren JS, van Laar JM, Pathare S, Proudman S, Rudin A, Sahhar J, Coppere B, Serratrice C, Sheeran T, Veale DJ, Grange C, Trad GS, Denton CP. Treatment outcome in early diffuse cutaneous systemic sclerosis: the European Scleroderma Observational Study (ESOS). Ann Rheum Dis. 2017 Jul; 76(7):1207-1218. PMID: 28188239.
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    13. Saag KG, Fitz-Patrick D, Kopicko J, Fung M, Bhakta N, Adler S, Storgard C, Baumgartner S, Becker MA. Lesinurad Combined With Allopurinol: A Randomized, Double-Blind, Placebo-Controlled Study in Gout Patients With an Inadequate Response to Standard-of-Care Allopurinol (a US-Based Study). Arthritis Rheumatol. 2017 01; 69(1):203-212. PMID: 27564409.
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    14. Becker MA. Summary of the 2015 Purine and Pyrimidine Society/Purine Metabolic Patients Association H. Anne Simmonds Memorial Lecture. Nucleosides Nucleotides Nucleic Acids. 2016 Dec; 35(10-12):502-506. PMID: 27906633.
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    15. Saag KG, Whelton A, Becker MA, MacDonald P, Hunt B, Gunawardhana L. Impact of Febuxostat on Renal Function in Gout Patients With Moderate-to-Severe Renal Impairment. Arthritis Rheumatol. 2016 08; 68(8):2035-43. PMID: 26894653.
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    16. Dhakal S, Bates JE, Casulo C, Friedberg JW, Becker MW, Liesveld JL, Constine LS. Patterns and Timing of Failure for Diffuse Large B-Cell Lymphoma After Initial Therapy in a Cohort Who Underwent Autologous Bone Marrow Transplantation for Relapse. Int J Radiat Oncol Biol Phys. 2016 10 01; 96(2):372-378. PMID: 27473813.
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    17. Schroeder J, Hamada S, Gründlinger N, Rubeau T, Altiok E, Ulbrich K, Keszei A, Marx N, Becker M. Myocardial deformation by strain echocardiography identifies patients with acute coronary syndrome and non-diagnostic ECG presenting in a chest pain unit: a prospective study of diagnostic accuracy. Clin Res Cardiol. 2016 Mar; 105(3):248-56. PMID: 26349786.
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    18. Becker MA, Fitz-Patrick D, Choi HK, Dalbeth N, Storgard C, Cravets M, Baumgartner S. An open-label, 6-month study of allopurinol safety in gout: The LASSO study. Semin Arthritis Rheum. 2015 Oct; 45(2):174-83. PMID: 26190562.
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    19. Chang J, McGrory BJ, Rana A, Becker MW, Babikian GM, Guay P, Smith KA. Current Orthopaedic Surgeon Practices for Nonarthroplasty Treatment of Osteoarthritis of Adult Hip and Knee. J Surg Orthop Adv. 2015; 24(4):213-20. PMID: 26731383.
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    20. Perez-Ruiz F, Becker MA. Inflammation: a possible mechanism for a causative role of hyperuricemia/gout in cardiovascular disease. Curr Med Res Opin. 2015; 31 Suppl 2:9-14. PMID: 26414731.
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    21. Baraf HS, Yood RA, Ottery FD, Sundy JS, Becker MA. Infusion-related reactions with pegloticase, a recombinant uricase for the treatment of chronic gout refractory to conventional therapy. J Clin Rheumatol. 2014 Dec; 20(8):427-32. PMID: 25417679.
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    22. Becker M, Hundemer A, Zwicker C, Altiok E, Krohn T, Mottaghy FM, Lente C, Kelm M, Marx N, Hoffmann R. Detection of coronary artery disease in postmenopausal women: the significance of integrated stress imaging tests in a 4-year prognostic study. Clin Res Cardiol. 2015 Mar; 104(3):258-71. PMID: 25367244.
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    23. Becker MA, Simkin PA, Sorensen LB. Urate transporters: transforming the face of hyperuricemia and gout. J Rheumatol. 2014 Oct; 41(10):1910-2. PMID: 25179848.
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    24. Guzman ML, Yang N, Sharma KK, Balys M, Corbett CA, Jordan CT, Becker MW, Steidl U, Abdel-Wahab O, Levine RL, Marcucci G, Roboz GJ, Hassane DC. Selective activity of the histone deacetylase inhibitor AR-42 against leukemia stem cells: a novel potential strategy in acute myelogenous leukemia. Mol Cancer Ther. 2014 Aug; 13(8):1979-90. PMID: 24934933.
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    25. Lipsky PE, Calabrese LH, Kavanaugh A, Sundy JS, Wright D, Wolfson M, Becker MA. Pegloticase immunogenicity: the relationship between efficacy and antibody development in patients treated for refractory chronic gout. Arthritis Res Ther. 2014 Mar 04; 16(2):R60. PMID: 24588936.
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    26. Advani AS, McDonough S, Coutre S, Wood B, Radich J, Mims M, O'Donnell M, Elkins S, Becker M, Othus M, Appelbaum FR. SWOG S0910: a phase 2 trial of clofarabine/cytarabine/epratuzumab for relapsed/refractory acute lymphocytic leukaemia. Br J Haematol. 2014 May; 165(4):504-9. PMID: 24579885.
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    27. Chaichian Y, Chohan S, Becker MA. Long-term management of gout: nonpharmacologic and pharmacologic therapies. Rheum Dis Clin North Am. 2014 May; 40(2):357-74. PMID: 24703352.
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    28. Wertheimer A, Morlock R, Becker MA. A revised estimate of the burden of illness of gout. Curr Ther Res Clin Exp. 2013 Dec; 75:1-4. PMID: 24465034.
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    29. Liesveld JL, Phillips GL, Becker M, Constine LS, Friedberg J, Andolina JR, Milner LA, DeBolt J, Smudzin T, Hyrien O, Erickson-Miller CL, Johnson BM, Dawson KL, Chen Y. A phase 1 trial of eltrombopag in patients undergoing stem cell transplantation after total body irradiation. Biol Blood Marrow Transplant. 2013 Dec; 19(12):1745-52. PMID: 24120380.
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    30. Baraf HS, Becker MA, Gutierrez-Urena SR, Treadwell EL, Vazquez-Mellado J, Rehrig CD, Ottery FD, Sundy JS, Yood RA. Tophus burden reduction with pegloticase: results from phase 3 randomized trials and open-label extension in patients with chronic gout refractory to conventional therapy. Arthritis Res Ther. 2013 Sep 26; 15(5):R137. PMID: 24286509.
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    31. Liesveld JL, O'Dwyer K, Walker A, Becker MW, Ifthikharuddin JJ, Mulford D, Chen R, Bechelli J, Rosell K, Minhajuddin M, Jordan CT, Phillips GL. A phase I study of decitabine and rapamycin in relapsed/refractory AML. Leuk Res. 2013 Dec; 37(12):1622-7. PMID: 24138944.
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    32. Hashmi S, Oliva JL, Liesveld JL, Phillips GL, Milner L, Becker MW. The hematopoietic cell transplantation specific comorbidity index and survival after extracorporeal photopheresis, pentostatin, and reduced dose total body irradiation conditioning prior to allogeneic stem cell transplantation. Leuk Res. 2013 Sep; 37(9):1052-6. PMID: 23830733.
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    33. Becker MA, MacDonald PA, Hunt BJ, Jackson RL. Diabetes and gout: efficacy and safety of febuxostat and allopurinol. Diabetes Obes Metab. 2013 Nov; 15(11):1049-55. PMID: 23683134.
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    34. Becker MA, Baraf HS, Yood RA, Dillon A, Vázquez-Mellado J, Ottery FD, Khanna D, Sundy JS. Long-term safety of pegloticase in chronic gout refractory to conventional treatment. Ann Rheum Dis. 2013 Sep 01; 72(9):1469-74. PMID: 23144450.
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    35. Komori M, Matsuyama Y, Nirasawa T, Thiele H, Becker M, Alexandrov T, Saida T, Tanaka M, Matsuo H, Tomimoto H, Takahashi R, Tashiro K, Ikegawa M, Kondo T. Proteomic pattern analysis discriminates among multiple sclerosis-related disorders. Ann Neurol. 2012 May; 71(5):614-23. PMID: 22522477.
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    36. Becker MA. Ser médico ...as a physician and professor at the University of Chicago. Rev Clin Esp. 2012 Mar; 212(3):151-4. PMID: 22532983.
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    37. Chohan S, Becker MA, MacDonald PA, Chefo S, Jackson RL. Women with gout: efficacy and safety of urate-lowering with febuxostat and allopurinol. Arthritis Care Res (Hoboken). 2012 Feb; 64(2):256-61. PMID: 22052584.
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    38. Becker MA, MacDonald PA, Hunt B, Gunawardhana L. Treating hyperuricemia of gout: safety and efficacy of febuxostat and allopurinol in older versus younger subjects. Nucleosides Nucleotides Nucleic Acids. 2011 Dec; 30(12):1011-7. PMID: 22132950.
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    39. Bruand J, Alexandrov T, Sistla S, Wisztorski M, Meriaux C, Becker M, Salzet M, Fournier I, Macagno E, Bafna V. AMASS: algorithm for MSI analysis by semi-supervised segmentation. J Proteome Res. 2011 Oct 07; 10(10):4734-43. PMID: 21800894.
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    40. Sundy JS, Baraf HS, Yood RA, Edwards NL, Gutierrez-Urena SR, Treadwell EL, Vázquez-Mellado J, White WB, Lipsky PE, Horowitz Z, Huang W, Maroli AN, Waltrip RW, Hamburger SA, Becker MA. Efficacy and tolerability of pegloticase for the treatment of chronic gout in patients refractory to conventional treatment: two randomized controlled trials. JAMA. 2011 Aug 17; 306(7):711-20. PMID: 21846852.
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    41. Singh JA, Taylor WJ, Simon LS, Khanna PP, Stamp LK, McQueen FM, Neogi T, Gaffo AL, Becker MA, MacDonald PA, Dabbous O, Strand V, Dalbeth ND, Aletaha D, Edwards NL, Schumacher HR. Patient-reported outcomes in chronic gout: a report from OMERACT 10. J Rheumatol. 2011 Jul; 38(7):1452-7. PMID: 21724715.
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    42. Taylor WJ, Singh JA, Saag KG, Dalbeth N, MacDonald PA, Edwards NL, Simon LS, Stamp LK, Neogi T, Gaffo AL, Khanna PP, Becker MA, Schumacher HR. Bringing it all together: a novel approach to the development of response criteria for chronic gout clinical trials. J Rheumatol. 2011 Jul; 38(7):1467-70. PMID: 21724718.
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    43. Dalbeth N, McQueen FM, Singh JA, MacDonald PA, Edwards NL, Schumacher HR, Simon LS, Stamp LK, Neogi T, Gaffo AL, Khanna PP, Becker MA, Taylor WJ. Tophus measurement as an outcome measure for clinical trials of chronic gout: progress and research priorities. J Rheumatol. 2011 Jul; 38(7):1458-61. PMID: 21724716.
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    44. Stamp LK, Khanna PP, Dalbeth N, Boers M, Maksymowych WP, Schumacher HR, Becker MA, MacDonald PA, Edwards NL, Singh JA, Simon LS, McQueen FM, Neogi T, Gaffo AL, Strand V, Taylor WJ. Serum urate in chronic gout--will it be the first validated soluble biomarker in rheumatology? J Rheumatol. 2011 Jul; 38(7):1462-6. PMID: 21724717.
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    45. Milner LA, Becker MW, Bernstein SH, Bruckner L, Friedberg JW, Holland GA, Ifthikharuddin JJ, Liesveld JL, Mathes EJ, Menchel HL, Mullen CA, Sasson T, Phillips GL. Intra-arterial methylprednisolone for the management of steroid-refractory acute gastrointestinal and hepatic graft versus host disease. Am J Hematol. 2011 Aug; 86(8):712-4. PMID: 21630317.
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    46. Claure N, Bancalari E, D'Ugard C, Nelin L, Stein M, Ramanathan R, Hernandez R, Donn SM, Becker M, Bachman T. Multicenter crossover study of automated control of inspired oxygen in ventilated preterm infants. Pediatrics. 2011 Jan; 127(1):e76-83. PMID: 21187305.
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    47. Edwards NL, Sundy JS, Forsythe A, Blume S, Pan F, Becker MA. Work productivity loss due to flares in patients with chronic gout refractory to conventional therapy. J Med Econ. 2011; 14(1):10-5. PMID: 21138339.
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    48. Phillips GL, Bernstein SH, Liesveld JL, Abboud CN, Becker MW, Constine LS, Ifthikharuddin JJ, Loughner JE, Milner LA, Vesole DH, Friedberg JW. A Phase I trial: dose escalation of melphalan in the "BEAM" regimen using amifostine cytoprotection. Biol Blood Marrow Transplant. 2011 Jul; 17(7):1033-42. PMID: 21074630.
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    49. Becker MA, Ruoff GE. What do I need to know about gout? J Fam Pract. 2010 Jun; 59(6 Suppl):S1-8. PMID: 20544070.
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    50. Becker MA, Schumacher HR, Espinoza LR, Wells AF, MacDonald P, Lloyd E, Lademacher C. The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial. Arthritis Res Ther. 2010; 12(2):R63. PMID: 20370912.
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    51. Knackstedt C, Mühlenbruch G, Mischke K, Schummers G, Becker M, Kühl H, Franke A, Schmid M, Spuentrup E, Mahnken A, Lang RM, Kelm M, Günther RW, Schauerte P. Registration of coronary venous anatomy to the site of the latest mechanical contraction. Acta Cardiol. 2010 Apr; 65(2):161-70. PMID: 20458823.
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    52. Kozhevnikov M, Blazhenkova O, Becker M. Trade-off in object versus spatial visualization abilities: restriction in the development of visual-processing resources. Psychon Bull Rev. 2010 Feb; 17(1):29-35. PMID: 20081157.
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    53. Becker MA, Schumacher HR, Benjamin KL, Gorevic P, Greenwald M, Fessel J, Edwards L, Kawata AK, Frank L, Waltrip R, Maroli A, Huang B. Quality of life and disability in patients with treatment-failure gout. J Rheumatol. 2009 May; 36(5):1041-8. PMID: 19332629.
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    54. Becker MA, Schumacher HR, MacDonald PA, Lloyd E, Lademacher C. Clinical efficacy and safety of successful longterm urate lowering with febuxostat or allopurinol in subjects with gout. J Rheumatol. 2009 Jun; 36(6):1273-82. PMID: 19286847.
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    55. Chohan S, Becker MA. Update on emerging urate-lowering therapies. Curr Opin Rheumatol. 2009 Mar; 21(2):143-9. PMID: 19339925.
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    56. Schumacher HR, Becker MA, Lloyd E, MacDonald PA, Lademacher C. Febuxostat in the treatment of gout: 5-yr findings of the FOCUS efficacy and safety study. Rheumatology (Oxford). 2009 Feb; 48(2):188-94. PMID: 19141576.
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    57. Schumacher HR, Becker MA, Wortmann RL, Macdonald PA, Hunt B, Streit J, Lademacher C, Joseph-Ridge N. Effects of febuxostat versus allopurinol and placebo in reducing serum urate in subjects with hyperuricemia and gout: a 28-week, phase III, randomized, double-blind, parallel-group trial. Arthritis Rheum. 2008 Nov 15; 59(11):1540-8. PMID: 18975369.
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    58. Furie R, Stohl W, Ginzler EM, Becker M, Mishra N, Chatham W, Merrill JT, Weinstein A, McCune WJ, Zhong J, Cai W, Freimuth W. Biologic activity and safety of belimumab, a neutralizing anti-B-lymphocyte stimulator (BLyS) monoclonal antibody: a phase I trial in patients with systemic lupus erythematosus. Arthritis Res Ther. 2008; 10(5):R109. PMID: 18786258.
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    59. Sundy JS, Becker MA, Baraf HS, Barkhuizen A, Moreland LW, Huang W, Waltrip RW, Maroli AN, Horowitz Z. Reduction of plasma urate levels following treatment with multiple doses of pegloticase (polyethylene glycol-conjugated uricase) in patients with treatment-failure gout: results of a phase II randomized study. Arthritis Rheum. 2008 Sep; 58(9):2882-91. PMID: 18759308.
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    60. O'Reilly DA, Witt H, Rahman SH, Schulz HU, Sargen K, Kage A, Cartmell MT, Landt O, Larvin M, Demaine AG, McMahon MJ, Becker M, Kingsnorth AN. The SPINK1 N34S variant is associated with acute pancreatitis. Eur J Gastroenterol Hepatol. 2008 Aug; 20(8):726-31. PMID: 18617776.
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    61. Walker AR, Komrokji RS, Ifthikharuddin J, Messina P, Mulford D, Becker M, Friedberg J, Oliva J, Phillips G, Liesveld JL, Abboud C. Phase I study of cladribine, cytarabine (Ara-C), granulocyte colony stimulating factor (G-CSF) (CLAG Regimen) and simultaneous escalating doses of imatinib mesylate (Gleevec) in relapsed/refractory AML. Leuk Res. 2008 Dec; 32(12):1830-6. PMID: 18571721.
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    62. Laughlin TS, Becker MW, Liesveld JL, Mulford DA, Abboud CN, Brown P, Rothberg PG. Rapid method for detection of mutations in the nucleophosmin gene in acute myeloid leukemia. J Mol Diagn. 2008 Jul; 10(4):338-45. PMID: 18556765.
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    63. Becker MA, Sabina RL. PP07: new approaches, new knowledge, new challenges in human purine and pyrimidine metabolism. Nucleosides Nucleotides Nucleic Acids. 2008 Jun; 27(6):547-53. PMID: 18600501.
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    64. Becker MA, Friedmann T, Raivio KO, Hershfield MS, Nuki G. In memoriam: J. Edwin Seegmiller, M.D. (1920-2006). Nucleosides Nucleotides Nucleic Acids. 2008 Jun; 27(6):554-6. PMID: 18600502.
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    65. Becker MA, MacDonald PA, Hunt BJ, Lademacher C, Joseph-Ridge N. Determinants of the clinical outcomes of gout during the first year of urate-lowering therapy. Nucleosides Nucleotides Nucleic Acids. 2008 Jun; 27(6):585-91. PMID: 18600509.
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    66. Becker M, Erdmann N, Stegemann E, Benke D, Schauerte PN, Schaefer WM, Autschbach R, Kelm M, Koch KC. Survival and quality of life in patients with cardiac resynchronization therapy for severe heart failure and in heart transplant recipients within a contemporary heart failure management program. J Heart Lung Transplant. 2008 Jul; 27(7):746-52. PMID: 18582804.
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    67. Becker MA, Chohan S. We can make gout management more successful now. Curr Opin Rheumatol. 2008 Mar; 20(2):167-72. PMID: 18349746.
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    68. Taylor WJ, Schumacher HR, Baraf HS, Chapman P, Stamp L, Doherty M, McQueen F, Dalbeth N, Schlesinger N, Furst DE, Vazquez-Mellado J, Mellado JV, Becker MA, Kavanaugh A, Louthrenoo W, Bardin T, Khanna D, Simon LS, Yamanaka H, Choi HK, Zeng X, Strand V, Grainger R, Clegg D, Singh JA, Diaz-Torne C, Boers M, Gow P, Barskova VG. A modified Delphi exercise to determine the extent of consensus with OMERACT outcome domains for studies of acute and chronic gout. Ann Rheum Dis. 2008 Jun; 67(6):888-91. PMID: 18055475.
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    69. Schumacher HR, Taylor W, Joseph-Ridge N, Perez-Ruiz F, Chen LX, Schlesinger N, Khanna D, Furst DE, Becker MA, Dalbeth N, Edwards NL. Outcome evaluations in gout. J Rheumatol. 2007 Jun; 34(6):1381-5. PMID: 17552064.
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    70. Becker MA, Donn SM. Real-time pulmonary graphic monitoring. Clin Perinatol. 2007 Mar; 34(1):1-17, v. PMID: 17394927.
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    71. Chohan S, Becker MA. Does diuretic use increase the risk of recurrent gout flares? Nat Clin Pract Rheumatol. 2006 Dec; 2(12):650-1. PMID: 17133248.
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    72. Becker MA, Jolly M. Hyperuricemia and associated diseases. Rheum Dis Clin North Am. 2006 May; 32(2):275-93, v-vi. PMID: 16716880.
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    73. Ellman MH, Becker MA. Crystal-induced arthropathies: recent investigative advances. Curr Opin Rheumatol. 2006 May; 18(3):249-55. PMID: 16582687.
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    74. Terkeltaub R, Bushinsky DA, Becker MA. Recent developments in our understanding of the renal basis of hyperuricemia and the development of novel antihyperuricemic therapeutics. Arthritis Res Ther. 2006; 8 Suppl 1:S4. PMID: 16820043.
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    75. Schumacher HR, Becker MA, Edwards NL, Palmer WE, MacDonald PA, Palo W, Joseph-Ridge N. Magnetic resonance imaging in the quantitative assessment of gouty tophi. Int J Clin Pract. 2006 Apr; 60(4):408-14. PMID: 16620352.
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    76. Becker MA, Schumacher HR, Wortmann RL, MacDonald PA, Eustace D, Palo WA, Streit J, Joseph-Ridge N. Febuxostat compared with allopurinol in patients with hyperuricemia and gout. N Engl J Med. 2005 Dec 08; 353(23):2450-61. PMID: 16339094.
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    77. Schumacher HR, Becker MA, Palo WA, Streit J, MacDonald PA, Joseph-Ridge N. Tophaceous gout: quantitative evaluation by direct physical measurement. J Rheumatol. 2005 Dec; 32(12):2368-72. PMID: 16331766.
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    78. Schumacher HR, Edwards LN, Perez-Ruiz F, Becker M, Chen LX, Furst DE, Joseph-Ridge N, Schlesinger N, Horowitz Z, Saag K, Boice JA, Yamanaka H. Outcome measures for acute and chronic gout. J Rheumatol. 2005 Dec; 32(12):2452-5. PMID: 16331785.
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    79. Uberti JP, Ayash L, Ratanatharathorn V, Silver S, Reynolds C, Becker M, Reddy P, Cooke KR, Yanik G, Whitfield J, Jones D, Hutchinson R, Braun T, Ferrara JL, Levine JE. Pilot trial on the use of etanercept and methylprednisolone as primary treatment for acute graft-versus-host disease. Biol Blood Marrow Transplant. 2005 Sep; 11(9):680-7. PMID: 16125638.
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    80. Becker MA, Schumacher HR, Wortmann RL, MacDonald PA, Palo WA, Eustace D, Vernillet L, Joseph-Ridge N. Febuxostat, a novel nonpurine selective inhibitor of xanthine oxidase: a twenty-eight-day, multicenter, phase II, randomized, double-blind, placebo-controlled, dose-response clinical trial examining safety and efficacy in patients with gout. Arthritis Rheum. 2005 Mar; 52(3):916-23. PMID: 15751090.
      View in: PubMed
    81. Takano Y, Hase-Aoki K, Horiuchi H, Zhao L, Kasahara Y, Kondo S, Becker MA. Selectivity of febuxostat, a novel non-purine inhibitor of xanthine oxidase/xanthine dehydrogenase. Life Sci. 2005 Mar 04; 76(16):1835-47. PMID: 15698861.
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    82. Attar MA, Becker MA, Dechert RE, Donn SM. Immediate changes in lung compliance following natural surfactant administration in premature infants with respiratory distress syndrome: a controlled trial. J Perinatol. 2004 Oct; 24(10):626-30. PMID: 15201857.
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    83. Becker MA, Kisicki J, Khosravan R, Wu J, Mulford D, Hunt B, MacDonald P, Joseph-Ridge N. Febuxostat (TMX-67), a novel, non-purine, selective inhibitor of xanthine oxidase, is safe and decreases serum urate in healthy volunteers. Nucleosides Nucleotides Nucleic Acids. 2004 Oct; 23(8-9):1111-6. PMID: 15571211.
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    84. Kelly D, Jara P, Rodeck B, Lykavieris P, Burdelski M, Becker M, Gridelli B, Boillot O, Manzanares J, Reding R. Tacrolimus and steroids versus ciclosporin microemulsion, steroids, and azathioprine in children undergoing liver transplantation: randomised European multicentre trial. Lancet. 2004 Sep 18-24; 364(9439):1054-61. PMID: 15380964.
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    85. Cooper A, Galbreath N, Becker MA. Sex on the internet: furthering our understanding of men with online sexual problems. Psychol Addict Behav. 2004 Sep; 18(3):223-30. PMID: 15482077.
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    86. Riedel AA, Nelson M, Joseph-Ridge N, Wallace K, MacDonald P, Becker M. Compliance with allopurinol therapy among managed care enrollees with gout: a retrospective analysis of administrative claims. J Rheumatol. 2004 Aug; 31(8):1575-81. PMID: 15290738.
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    87. Ratanatharathorn V, Ayash L, Reynolds C, Silver S, Reddy P, Becker M, Ferrara JL, Uberti JP. Treatment of chronic graft-versus-host disease with anti-CD20 chimeric monoclonal antibody. Biol Blood Marrow Transplant. 2003 Aug; 9(8):505-11. PMID: 12931119.
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    88. García-Pavía P, Torres RJ, Rivero M, Ahmed M, García-Puig J, Becker MA. Phosphoribosylpyrophosphate synthetase overactivity as a cause of uric acid overproduction in a young woman. Arthritis Rheum. 2003 Jul; 48(7):2036-41. PMID: 12847698.
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    89. Klapman JB, Ene-Stroescu D, Becker MA, Hanauer SB. A lupus-like syndrome associated with infliximab therapy. Inflamm Bowel Dis. 2003 May; 9(3):176-8. PMID: 12792223.
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    90. Choi-Sledeski YM, Kearney R, Poli G, Pauls H, Gardner C, Gong Y, Becker M, Davis R, Spada A, Liang G, Chu V, Brown K, Collussi D, Leadley R, Rebello S, Moxey P, Morgan S, Bentley R, Kasiewski C, Maignan S, Guilloteau JP, Mikol V. Discovery of an orally efficacious inhibitor of coagulation factor Xa which incorporates a neutral P1 ligand. J Med Chem. 2003 Feb 27; 46(5):681-4. PMID: 12593648.
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    91. Bhatia E, Choudhuri G, Sikora SS, Landt O, Kage A, Becker M, Witt H. Tropical calcific pancreatitis: strong association with SPINK1 trypsin inhibitor mutations. Gastroenterology. 2002 Oct; 123(4):1020-5. PMID: 12360463.
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    92. Oca MJ, Becker MA, Dechert RE, Donn SM. Relationship of neonatal endotracheal tube size and airway resistance. Respir Care. 2002 Sep; 47(9):994-7. PMID: 12188933.
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    93. Rezai KA, Patel SC, Eliott D, Becker MA. Rheumatoid hyperviscosity syndrome: reversibility of microvascular abnormalities after treatment. Am J Ophthalmol. 2002 Jul; 134(1):130-2. PMID: 12095825.
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    94. Truninger K, Witt H, Köck J, Kage A, Seifert B, Ammann RW, Blum HE, Becker M. Mutations of the serine protease inhibitor, Kazal type 1 gene, in patients with idiopathic chronic pancreatitis. Am J Gastroenterol. 2002 May; 97(5):1133-7. PMID: 12014716.
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    95. Becker MA. Phosphoribosylpyrophosphate synthetase and the regulation of phosphoribosylpyrophosphate production in human cells. Prog Nucleic Acid Res Mol Biol. 2001; 69:115-48. PMID: 11550793.
      View in: PubMed
    96. Tung BJ, Becker MA. Modes of neonatal and pediatric ventilation. Air Med J. 2001 Jan-Feb; 20(1):12-3. PMID: 11182698.
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    97. Becker MA, Ahmed M. Cell type-specific differential expression of human PRPP synthetase (PRPS) genes. Adv Exp Med Biol. 2000; 486:5-10. PMID: 11783526.
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    98. Ahmed M, Taylor W, Smith PR, Becker MA. Accelerated transcription of PRPS1 in X-linked overactivity of normal human phosphoribosylpyrophosphate synthetase. J Biol Chem. 1999 Mar 12; 274(11):7482-8. PMID: 10066814.
      View in: PubMed
    99. Wilson BJ, Becker MA, Linton ME, Donn SM. Spontaneous minute ventilation predicts readiness for extubation in mechanically ventilated preterm infants. J Perinatol. 1998 Nov-Dec; 18(6 Pt 1):436-9. PMID: 9848756.
      View in: PubMed
    100. Becker MA, Taylor W, Smith PR, Ahmed M. Regulation of human PRS isoform expression. Adv Exp Med Biol. 1998; 431:215-20. PMID: 9598062.
      View in: PubMed
    101. Nelson M, Nicks JJ, Becker MA, Vrlenich LA, Bhatt-Mehta V, Schumacher RE. Comparison of two methods of surfactant administration and the effect on dosing-associated hypoxemia. J Perinatol. 1997 Nov-Dec; 17(6):450-4. PMID: 9447531.
      View in: PubMed
    102. Becker MA, Taylor W, Smith PR, Ahmed M. Overexpression of the normal phosphoribosylpyrophosphate synthetase 1 isoform underlies catalytic superactivity of human phosphoribosylpyrophosphate synthetase. J Biol Chem. 1996 Aug 16; 271(33):19894-9. PMID: 8702702.
      View in: PubMed
    103. Attar MA, Becker MA, Nicks JJ, Faix RG. Ventilatory management casebook. Successful treatment of pulmonary interstitial emphysema with high-frequency oscillation after unsuccessful high-frequency jet ventilation. J Perinatol. 1996 May-Jun; 16(3 Pt 1):222-30. PMID: 8817438.
      View in: PubMed
    104. Torres RJ, Mateos FA, Puig JG, Becker MA. Determination of phosphoribosylpyrophosphate synthetase activity in human cells by a non-isotopic, one step method. Clin Chim Acta. 1996 Feb 09; 245(1):105-12. PMID: 8646809.
      View in: PubMed
    105. Becker MA, Smith PR, Taylor W, Mustafi R, Switzer RL. The genetic and functional basis of purine nucleotide feedback-resistant phosphoribosylpyrophosphate synthetase superactivity. J Clin Invest. 1995 Nov; 96(5):2133-41. PMID: 7593598.
      View in: PubMed
    106. Fry DW, Becker MA, Switzer RL. Inhibition of human 5-phosphoribosyl-1-pyrophosphate synthetase by 4-amino-8-(beta-D-ribofuranosylamino)-pyrimido[5,4-d]pyrimidine-5'- monophosphate: evidence for interaction at the ADP allosteric site. Mol Pharmacol. 1995 Apr; 47(4):810-5. PMID: 7723742.
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    107. Nicks JJ, Becker MA, Donn SM. Ventilatory management casebook. Bronchopulmonary dysplasias. Response to pressure support ventilation. J Perinatol. 1994 Nov-Dec; 14(6):495-7. PMID: 7876945.
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    108. Donn SM, Nicks JJ, Becker MA. Flow-synchronized ventilation of preterm infants with respiratory distress syndrome. J Perinatol. 1994 Mar-Apr; 14(2):90-4. PMID: 8014707.
      View in: PubMed
    109. Torres RJ, Mateos FA, Puig JG, Becker MA. A simplified method for the determination of phosphoribosylpyrophosphate synthetase activity in hemolysates. Clin Chim Acta. 1994 Jan 14; 224(1):55-63. PMID: 8174278.
      View in: PubMed
    110. Torres R, Mateos F, Puig JG, Becker MA. Determination of the activity of recombinant human phosphoribosylpyrophosphate synthetase isoform 1 by a non-isotopic, one-step method. Adv Exp Med Biol. 1994; 370:821-4. PMID: 7661031.
      View in: PubMed
    111. Becker MA, Nosal JM, Switzer RL, Smith PR, Palella TD, Roessler BJ. Point mutations in PRPS1, the gene encoding the PRPP synthetase (PRS) 1 isoform, underlie X-linked PRS superactivity associated with purine nucleotide inhibitor-resistance. Adv Exp Med Biol. 1994; 370:707-10. PMID: 7661003.
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    112. Roessler BJ, Nosal JM, Smith PR, Heidler SA, Palella TD, Switzer RL, Becker MA. Human X-linked phosphoribosylpyrophosphate synthetase superactivity is associated with distinct point mutations in the PRPS1 gene. J Biol Chem. 1993 Dec 15; 268(35):26476-81. PMID: 8253776.
      View in: PubMed
    113. Nosal JM, Switzer RL, Becker MA. Overexpression, purification, and characterization of recombinant human 5-phosphoribosyl-1-pyrophosphate synthetase isozymes I and II. J Biol Chem. 1993 May 15; 268(14):10168-75. PMID: 8387514.
      View in: PubMed
    114. Nicks JJ, Becker MA, Donn SM. Ventilatory management casebook. Neonatal respiratory failure: response to volume ventilation. J Perinatol. 1993 Jan-Feb; 13(1):72-5. PMID: 8445451.
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    115. Becker MA, Kim M, Husain K, Kang T. Regulation of purine nucleotide synthesis in human B lymphoblasts with both hypoxanthine-guanine phosphoribosyltransferase deficiency and phosphoribosylpyrophosphate synthetase superactivity. J Biol Chem. 1992 Mar 05; 267(7):4317-21. PMID: 1311306.
      View in: PubMed
    116. Wang JC, Passage MB, Ellison J, Becker MA, Yen PH, Shapiro LJ, Mohandas TK. Physical mapping of loci in the distal half of the short arm of the human X chromosome: implications for the spreading of X-chromosome inactivation. Somat Cell Mol Genet. 1992 Mar; 18(2):195-200. PMID: 1315458.
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    117. Roessler BJ, Golovoy N, Palella TD, Heidler S, Becker MA. Identification of distinct PRS1 mutations in two patients with X-linked phosphoribosylpyrophosphate synthetase superactivity. Adv Exp Med Biol. 1991; 309B:125-8. PMID: 1664177.
      View in: PubMed
    118. Becker MA, Heidler SA, Nosal JM, Switzer RL, LeBeau MM, Shapiro LJ, Palella TD, Roessler BJ. Human phosphoribosylpyrophosphate synthetase (PRS) 2: an independent active, X chromosome-linked PRS isoform. Adv Exp Med Biol. 1991; 309B:129-32. PMID: 1723569.
      View in: PubMed
    119. Becker MA, Heidler SA, Bell GI, Seino S, Le Beau MM, Westbrook CA, Neuman W, Shapiro LJ, Mohandas TK, Roessler BJ, et al. Cloning of cDNAs for human phosphoribosylpyrophosphate synthetases 1 and 2 and X chromosome localization of PRPS1 and PRPS2 genes. Genomics. 1990 Nov; 8(3):555-61. PMID: 1962753.
      View in: PubMed
    120. Becker MA. Rheumatology. JAMA. 1989 May 19; 261(19):2887-8. PMID: 2709595.
      View in: PubMed
    121. Jiménez ML, Puig JG, Mateos FA, Ramos TH, Melián JS, Nieto VG, Becker MA. Increased purine nucleotide degradation in the central nervous system (CNS) in PRPP synthetase superactivity. Adv Exp Med Biol. 1989; 253A:9-13. PMID: 2560341.
      View in: PubMed
    122. Becker MA, Kim M, Husain K. PRPP and purine nucleotide metabolism in human lymphoblasts with both PRPP synthetase superactivity and HGPRT deficiency. Adv Exp Med Biol. 1989; 253B:13-20. PMID: 2481968.
      View in: PubMed
    123. Becker MA, Puig JG, Mateos FA, Jimenez ML, Kim M, Simmonds HA. Neurodevelopmental impairment and deranged PRPP and purine nucleotide synthesis in inherited superactivity of PRPP synthetase. Adv Exp Med Biol. 1989; 253A:15-22. PMID: 2483028.
      View in: PubMed
    124. Becker MA, Puig JG, Mateos FA, Jimenez ML, Kim M, Simmonds HA. Inherited superactivity of phosphoribosylpyrophosphate synthetase: association of uric acid overproduction and sensorineural deafness. Am J Med. 1988 Sep; 85(3):383-90. PMID: 2843048.
      View in: PubMed
    125. Becker MA. Clinical aspects of monosodium urate monohydrate crystal deposition disease (gout). Rheum Dis Clin North Am. 1988 Aug; 14(2):377-94. PMID: 3051156.
      View in: PubMed
    126. Carragher B, Bluemke DA, Becker M, McDade WA, Potel MJ, Josephs R. Structural analysis of polymers of sickle cell hemoglobin. III. Fibers within fascicles. J Mol Biol. 1988 Jan 20; 199(2):383-8. PMID: 3351930.
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    127. Becker MA, Kim M. Regulation of purine synthesis de novo in human fibroblasts by purine nucleotides and phosphoribosylpyrophosphate. J Biol Chem. 1987 Oct 25; 262(30):14531-7. PMID: 2444588.
      View in: PubMed
    128. Becker MA, Losman MJ, Kim M. Mechanisms of accelerated purine nucleotide synthesis in human fibroblasts with superactive phosphoribosylpyrophosphate synthetases. J Biol Chem. 1987 Apr 25; 262(12):5596-602. PMID: 3032938.
      View in: PubMed
    129. Becker MA, Losman MJ, Rosenberg AL, Mehlman I, Levinson DJ, Holmes EW. Phosphoribosylpyrophosphate synthetase superactivity. A study of five patients with catalytic defects in the enzyme. Arthritis Rheum. 1986 Jul; 29(7):880-8. PMID: 3017368.
      View in: PubMed
    130. Becker MA, Losman MJ, Wilson J, Simmonds HA. Superactivity of human phosphoribosyl pyrophosphate synthetase due to altered regulation by nucleotide inhibitors and inorganic phosphate. Biochim Biophys Acta. 1986 Jun 19; 882(2):168-76. PMID: 2423135.
      View in: PubMed
    131. Becker MA, Losman MJ, Rimon D, Kim M. PRPP synthetase superactivity in lymphoblast lines. Adv Exp Med Biol. 1986; 195 Pt A:51-8. PMID: 3014839.
      View in: PubMed
    132. Becker MA, Losman MJ, Simmonds HA. Inherited phosphoribosylpyrophosphate synthetase superactivity due to aberrant inhibitor and activator responsiveness. Adv Exp Med Biol. 1986; 195 Pt A:59-66. PMID: 3014841.
      View in: PubMed
    133. Losman MJ, Rimon D, Kim M, Becker MA. Selective expression of phosphoribosylpyrophosphate synthetase superactivity in human lymphoblast lines. J Clin Invest. 1985 Oct; 76(4):1657-64. PMID: 2414323.
      View in: PubMed
    134. Itkin P, Woo S, Becker MA. Human phosphoribosylpyrophosphate synthetase: radioimmunochemical quantitation in erythrocytes and fibroblasts. J Lab Clin Med. 1984 Jul; 104(1):96-109. PMID: 6330252.
      View in: PubMed
    135. Losman MJ, Hecker S, Woo S, Becker MA. Diagnostic evaluation of phosphoribosylpyrophosphate synthetase activities in hemolysates. J Lab Clin Med. 1984 Jun; 103(6):932-43. PMID: 6327865.
      View in: PubMed
    136. Sabina RL, Holmes EW, Becker MA. The enzymatic synthesis of 5-amino-4-imidazolecarboxamide riboside triphosphate (ZTP). Science. 1984 Mar 16; 223(4641):1193-5. PMID: 6199843.
      View in: PubMed
    137. Becker MA, Itkin P. Radioimmunoassay studies of human phosphoribosylpyrophosphate synthetase. Adv Exp Med Biol. 1984; 165 Pt B:5-10. PMID: 6326507.
      View in: PubMed
    138. Losman MJ, Becker MA. Human phosphoribosylpyrophosphate (PRPP) synthetase requirements for subunit aggregation. Adv Exp Med Biol. 1984; 165 Pt A:427-32. PMID: 6326486.
      View in: PubMed
    139. Becker MA. Phosphoribosylpyrophosphate synthetase superactivity: detection, characterization of underlying defects, and treatment. Adv Exp Med Biol. 1984; 165 Pt A:91-96. PMID: 6326492.
      View in: PubMed
    140. Becker MA, Dicker P, Rozengurt E. Mitogenic enhancement of purine base phosphoribosylation in Swiss mouse 3T3 cells. Am J Physiol. 1983 Mar; 244(3):C288-96. PMID: 6187219.
      View in: PubMed
    141. Becker MA, Losman MJ, Itkin P, Simkin PA. Gout with superactive phosphoribosylpyrophosphate synthetase due to increased enzyme catalytic rate. J Lab Clin Med. 1982 Apr; 99(4):495-511. PMID: 6174658.
      View in: PubMed
    142. Raivio KO, Lazar CS, Becker MA. Regulation of 5-phosphoribosyl-1-pyrophosphate synthesis in human fibroblasts by the concentration of inorganic phosphate. Biochim Biophys Acta. 1981 Nov 18; 678(1):58-64. PMID: 6171306.
      View in: PubMed
    143. Raivio KO, Lazar CS, Krumholz HR, Becker MA. The phosphogluconate pathway and synthesis of 5-phosphoribosyl-1-pyrophosphate in human fibroblasts. Biochim Biophys Acta. 1981 Nov 18; 678(1):51-7. PMID: 6171305.
      View in: PubMed
    144. Yen RC, Raivio KO, Becker MA. Inhibition of phosphoribosylpyrophosphate synthesis in human fibroblasts by 6-methylthioinosinate. J Biol Chem. 1981 Feb 25; 256(4):1839-45. PMID: 6257688.
      View in: PubMed
    145. Becker MA, Raivio KO, Bakay B, Adams WB, Nyhan WL. Variant human phosphoribosylpyrophosphate synthetase altered in regulatory and catalytic functions. J Clin Invest. 1980 Jan; 65(1):109-20. PMID: 6243137.
      View in: PubMed
    146. Becker MA, Raivio KO, Bakay B, Adams WB, Nyhan WL. Superactive phosphoribosylpyrophosphate synthetase with altered regulatory and catalytic properties. Adv Exp Med Biol. 1980; 122A:387-92. PMID: 6158850.
      View in: PubMed
    147. Huisman WH, Raivio KO, Becker MA. Simultaneous estimation of rates of pyrimidine and purine nucleotide synthesis de novo in cultured human cells. J Biol Chem. 1979 Dec 25; 254(24):12595-602. PMID: 500731.
      View in: PubMed
    148. Becker MA, Yen RC, Itkin P, Goss SJ, Seegmiller JE, Bakay B. Regional localization of the gene for human phosphoribosylpyrophosphate synthetase on the X chromosome. Science. 1979 Mar 09; 203(4384):1016-9. PMID: 218284.
      View in: PubMed
    149. Yen RC, Becker MA. Methylmercaptopurine ribonucleoside toxicity in human fibroblasts: inhibition of phosphoribosylpyrophosphate synthetase as well as amidophosphoribosyltransferase. Adv Exp Med Biol. 1979; 122B:137-43. PMID: 232627.
      View in: PubMed
    150. Huisman WH, Raivio KO, Becker MA. Simultaneous determination of rates of purine and pyrimidine synthesis in cultured human lymphoblasts and fibroblasts. Adv Exp Med Biol. 1979; 122B:223-9. PMID: 546147.
      View in: PubMed
    151. Becker MA, Raivio KO, Seegmiller JE. Synthesis of phosphoribosylpyrophosphate in mammalian cells. Adv Enzymol Relat Areas Mol Biol. 1979; 49:281-306. PMID: 95664.
      View in: PubMed
    152. Raivio KO, Lazar C, Krumholz H, Becker MA. Determinants of 5-phosphoribosyl-1-pyrophosphate (PRPP) synthesis in human fibroblasts. Adv Exp Med Biol. 1979; 122B:31-4. PMID: 94761.
      View in: PubMed
    153. Yen RC, Adams WB, Lazar C, Becker MA. Evidence for X-linkage of human phosphoribosylpyrophosphate synthetase. Proc Natl Acad Sci U S A. 1978 Jan; 75(1):482-5. PMID: 203941.
      View in: PubMed
    154. Weintraub M, Nash TE, Ottesen E, Becker MA. Uricosuric effects of niridazole. Clin Pharmacol Ther. 1977 Nov; 22(5 Pt 1):568-72. PMID: 913024.
      View in: PubMed
    155. Becker MA, Meyer LJ, Huisman WH, Lazar C, Adams WB. Human erythrocyte phosphoribosylpyrophosphate synthetase. Subunit analysis and states of subunit association. J Biol Chem. 1977 Jun 10; 252(11):3911-8. PMID: 193849.
      View in: PubMed
    156. Meyer LJ, Becker MA. Human erythrocyte phosphoribosylpyrophosphate synthetase. Dependence of activity on state of subunit association. J Biol Chem. 1977 Jun 10; 252(11):3919-25. PMID: 193850.
      View in: PubMed
    157. Becker MA. Fibroblast phosphoribosylpyrophosphate and ribose-5-phosphate concentration and generation in gout with purine overproduction. Adv Exp Med Biol. 1977; 76A:270-9. PMID: 193370.
      View in: PubMed
    158. Becker MA, Meyer LJ, Huisman WH, Lazar CS, Adams WB. Human phosphoribosylpyrophosphate synthetase: relation of activity and quaternary structure. Adv Exp Med Biol. 1977; 76A:71-9. PMID: 193379.
      View in: PubMed
    159. Sweetman L, Borden M, Lesh P, Bakay B, Becker MA. Diminished affinity for purine substrates as a basis for gout with mild deficiency of hypoxanthine-guanine phosphoribosyltransferase. Adv Exp Med Biol. 1977; 76A:319-25. PMID: 558714.
      View in: PubMed
    160. Becker MA. Effects of inosine on purine synthesis in normal and HGPRT-deficient human fibroblasts. Adv Exp Med Biol. 1977; 76A:370-5. PMID: 857618.
      View in: PubMed
    161. Bakay B, Becker MA, Nyhan WL. Reaction of antibody to normal human hypoxanthine phosphoribosyltransferase with products of mutant genes. Arch Biochem Biophys. 1976 Dec; 177(2):415-26. PMID: 1035076.
      View in: PubMed
    162. Dwosh IL, Resnick D, Becker MA. Hip involvement in ankylosing spondylitis. Arthritis Rheum. 1976 Jul-Aug; 19(4):683-92. PMID: 942499.
      View in: PubMed
    163. Becker MA. Regulation of purine nucleotide synthesis. Effects of inosine on normal and hypoxantine-guanine phosphoribosyltransferase-deficient fibroblasts. Biochim Biophys Acta. 1976 Jun 18; 435(2):132-44. PMID: 938674.
      View in: PubMed
    164. Becker MA. Patterns of phosphoribosylpyrophosphate and ribose-5-phosphate concentration and generation in fibroblasts from patients with gout and purine overproduction. J Clin Invest. 1976 Feb; 57(2):308-18. PMID: 176178.
      View in: PubMed
    165. Becker MA, Argubright KF, Seegmiller JE. Effects of oxipurinol on pyrimidine nucleotide synthesis in human lymphoblasts. Arthritis Rheum. 1975 Nov-Dec; 18(6 Suppl):871-6. PMID: 1201132.
      View in: PubMed
    166. Becker MA, Seegmiller JE. Recent advances in the identification of enzyme abnormalities underlying excessive purine synthesis in man. Arthritis Rheum. 1975 Nov-Dec; 18(6 Suppl):687-94. PMID: 173346.
      View in: PubMed
    167. Becker MA, Kostel PJ, Meyer LJ. Human phosphoribosylpyrophosphate synthetase. Comparison of purified normal and mutant enzymes. J Biol Chem. 1975 Sep 10; 250(17):6822-30. PMID: 169259.
      View in: PubMed
    168. Johnson MG, Rosenweig S, Switzer RL, Becker MA, Seegmiller JE. Evaluation of the role of 5-phosphoribosyl-alpha-1-pyrophosphate synthetase in congenital hyperuricemia and gout: a simple isotopic assay and an activity stain for the enzyme. Biochem Med. 1974 Jul; 10(3):266-75. PMID: 4366297.
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    169. Becker MA, Seegmiller JE. Genetic aspects of gout. Annu Rev Med. 1974; 25(0):15-28. PMID: 4604505.
      View in: PubMed
    170. Wood AW, Becker MA, Minna JD, Seegmiller JE. Purine metabolism in normal and thioguanine-resistant neuroblastoma. Proc Natl Acad Sci U S A. 1973 Dec; 70(12):3880-3. PMID: 4521214.
      View in: PubMed
    171. Becker MA, Kostel PJ, Meyer LJ, Seegmiller JE. Human phosphoribosylpyrophosphate synthetase: increased enzyme specific activity in a family with gout and excessive purine synthesis. Proc Natl Acad Sci U S A. 1973 Oct; 70(10):2749-52. PMID: 4200723.
      View in: PubMed
    172. Becker MA, Meyer LJ, Seegmiller JE. Gout with purine overproduction due to increased phosphoribosylpyrophosphate synthetase activity. Am J Med. 1973 Aug; 55(2):232-42. PMID: 4722859.
      View in: PubMed
    173. Wood AW, Becker MA, Seegmiller JE. Purine nucleotide synthesis in lymphoblasts cultured from normal subjects and a patient with Lesch-Nyhan syndrome. Biochem Genet. 1973 Jul; 9(3):261-74. PMID: 4354564.
      View in: PubMed
    174. Becker MA, Meyer LJ, Wood AW, Seegmiller JE. Purine overproduction in man associated with increased phosphoribosylpyrophosphate synthetase activity. Science. 1973 Mar 16; 179(4078):1123-6. PMID: 4347565.
      View in: PubMed
    175. Becker MA, Meyer LJ, Kostel PJ, Seegmiller JE. Increased PP-ribose-P synthetase activity: a genetic abnormality leading to excessive purine production and gout. Adv Exp Med Biol. 1973; 41:307-15. PMID: 4364688.
      View in: PubMed
    176. Boyle JA, Raivio KO, Becker MA, Seegmiller JE. Effects of nicotinic acid on human fibroblast purine biosynthesis. Biochim Biophys Acta. 1972 May 10; 269(2):179-83. PMID: 4337750.
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