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Andrey Rzhetsky

TitleProfessor
InstitutionUniversity of Chicago
DepartmentMedicine
AddressChicago IL 60637
Email
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    Collapse Research 
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    R01MH110905     (RZHETSKY, ANDREY)Jul 8, 2016 - Apr 30, 2020
    NIH
    2/2-Measuring translational dynamics and the proteome to identify potential brain biomarkers for psychiatric disease
    Role: Principal Investigator
    R01HL122712     (SOLWAY, JULIAN)Sep 1, 2015 - Jun 30, 2020
    NIH
    Mendelian Disease - Asthma Comorbidity to Find Subgroup-Specific Asthma Genes
    Role: Co-Principal Investigator
    U01MH103340     (LIU, CHUNYU)Jun 10, 2014 - May 31, 2019
    NIH
    Genetic variants affect brain gene expression and risks of psychiatric disorders
    Role: Co-Principal Investigator
    K12HL119995     (SOLWAY, JULIAN)Sep 1, 2013 - May 31, 2018
    NIH
    Training of Junior Faculty for Careers in Omics of Lung Diseases
    Role: Co-Principal Investigator
    P50MH094267     (RZHETSKY, ANDREY)Sep 22, 2011 - Aug 31, 2017
    NIH
    Conte Center for Computational Systems Genomics of Neuropsychiatric Phenotypes
    Role: Principal Investigator
    R01LM010132     (RZHETSKY, ANDREY)Jul 1, 2009 - Jun 30, 2012
    NIH
    Large-scale Discovery of Scientific Hypotheses;Computation Over Expert Opinions
    Role: Principal Investigator
    T32MH020065     (RZHETSKY, ANDREY)Apr 1, 2000 - Jun 30, 2018
    NIH
    Training in Emerging Multidisciplinary Approaches to Mental Health and Disease
    Role: Principal Investigator
    R01GM061372     (RZHETSKY, ANDREY)Apr 1, 2000 - Aug 31, 2011
    NIH
    Computer System for Functional Analysis of Genomic Data
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Bhui K, Newbury JB, Latham RM, Ucci M, Nasir ZA, Turner B, O'Leary C, Fisher HL, Marczylo E, Douglas P, Stansfeld S, Jackson SK, Tyrrel S, Rzhetsky A, Kinnersley R, Kumar P, Duchaine C, Coulon F. Air quality and mental health: evidence, challenges and future directions. BJPsych Open. 2023 Jul 05; 9(4):e120. PMID: 37403494; PMCID: PMC10375903.
      Citations:    
    2. Long Y, Khan A, Rzhetsky A. Peri- and Post-natal Risk Factors Associated with Health of Newborns: A pregnant mother's infections and immune diseases, and her baby's delivery method predict immune health of the newborn. medRxiv. 2023 Jan 17. PMID: 36711636; PMCID: PMC9882552.
      Citations:    
    3. Matthews JM, Schuster B, Kashaf SS, Liu P, Ben-Yishay R, Ishay-Ronen D, Izumchenko E, Shen L, Weber CR, Bielski M, Kupfer SS, Bilgic M, Rzhetsky A, Tay S. OrganoID: A versatile deep learning platform for tracking and analysis of single-organoid dynamics. PLoS Comput Biol. 2022 11; 18(11):e1010584. PMID: 36350878; PMCID: PMC9645660.
      Citations: 7     Fields:    
    4. Jia G, Zhong X, Im HK, Schoettler N, Pividori M, Hogarth DK, Sperling AI, White SR, Naureckas ET, Lyttle CS, Terao C, Kamatani Y, Akiyama M, Matsuda K, Kubo M, Cox NJ, Ober C, Rzhetsky A, Solway J. Discerning asthma endotypes through comorbidity mapping. Nat Commun. 2022 11 07; 13(1):6712. PMID: 36344522; PMCID: PMC9640644.
      Citations: 2     Fields:    Translation:Humans
    5. Zhang H, Khan A, Rzhetsky A. Gene-environment interactions explain a substantial portion of variability of common neuropsychiatric disorders. Cell Rep Med. 2022 09 20; 3(9):100736. PMID: 36070757; PMCID: PMC9512674.
      Citations:    Fields:    Translation:Humans
    6. Wang K, Moreira A, Grose A, Leahy K, Zhou Y, Clouser FA, Siddiqui M, Leong N, Goodall P, Michalowski M, Ismail M, Christmas M, Schrantz S, Raggi C, Castro C, Moossazadeh D, Ramirez M, Pandey A, Ashi K, Dovgin S, Dixon A, Li X, Begeman I, Heichman S, Lykins J, Wroblewski K, Karrison T, Ross S, Dogra M, Dhamsania V, Graves N, Kirchberg M, Mathur K, Aue A, Boyer K, Heydemann P, Noble AG, Swisher C, Rabiah P, Withers S, Hull T, Su C, Blair M, Latkany P, Mui E, Vasconcelos-Santos DV, Ramirez M, Chittenden C, Wang E, Padrieu G, Nicolae DL, Rzhetsky A, Roizen N, Stillwaggon E, Sawers L, Montoya J, Press C, Ramirez R, Contopoulos-Ioannidis D, Maldonado Y, Liesenfeld O, Gomez C, Wheeler K, Holfels E, Frim D, McLone D, Penn R, Cohen W, Zehar S, McAuley J, Limonne D, Houze S, Abraham S, Piarroux R, Tesic V, Beavis K, Abeleda A, Sautter M, El Mansouri B, El Bachir A, Amarir F, El Bissati K, Meier P, Grigg M, Felín MS, Caballero Z, Norero X, Estripeaut D, Ellis D, Villalobos-Cerrud D, Fabrega L, Montalvo JLS, Mendivil C, Quijada MR, Fernández-Pirla S, de La Guardia V, Wong D, de Guevara ML, Flores C, Borace J, García A, Caballero N, Rengifo-Herrera C, de Saez MTM, Politis M, Restrepo CM, Llanes A, Guzman G, Rebellon A, Villareal A, Perez A, Galvis CAN, Montes MV, Perez NIC, Garcia-López LL, Muñoz-Ortiz J, Rivera-Valdivia N, Bohorquez-Granados MC, de-la-Torre GC, Hernandez JDV, Celis-Giraldo D, Dávila JAA, Torres E, Oquendo MM, Arteaga-Rivera JY, Peyron F, Wallon M, Chapey E, Levigne P, Charter C, De Frias M, de-la-Torre A, Britton G, Motta J, Ortega-Barria E, Romero IL, Gómez-Marín J, Kosagisharaf JR, Llorens XS, Reyes O, McLeod R. Building Programs to Eradicate Toxoplasmosis Part I: Introduction and Overview. Curr Pediatr Rep. 2022; 10(3):57-92. PMID: 36034212; PMCID: PMC9395898.
      Citations: 1     
    7. Wang K, Moreira A, Grose A, Leahy K, Zhou Y, Clouser FA, Siddiqui M, Leong N, Goodall P, Michalowski M, Ismail M, Christmas M, Schrantz S, Raggi C, Castro C, Moossazadeh D, Ramirez M, Pandey A, Ashi K, Dovgin S, Dixon A, Li X, Begeman I, Heichman S, Lykins J, de La Guardia V, Politis M, Ross S, Dogra M, Dhamsania V, Graves N, Kirchberg M, Mathur K, Aue A, Rebellon A, Boyer K, Heydemann P, Noble AG, Swisher C, Rabiah P, Withers S, Hull T, Frim D, McLone D, Su C, Blair M, Latkany P, Mui E, Vasconcelos-Santos DV, Ramirez M, Chittenden C, Wang E, Padrieu G, Nicolae DL, Rzhetsky A, Roizen N, Stillwaggon E, Sawers L, Levigne P, Montoya J, Press C, Ramirez R, Contopoulos-Ioannidis D, Maldonado Y, Liesenfeld O, Gomez C, Wheeler K, Zehar S, McAuley J, Limonne D, Houze S, Abraham S, Piarroux R, Tesic V, Beavis K, Abeleda A, Sautter M, El Mansouri B, El Bachir A, Amarir F, El Bissati K, Holfels E, Penn R, Cohen W, Ortega-Barria E, Meier P, Grigg M, McLeod R, Felín MS, Caballero Z, Norero X, Estripeaut D, Ellis D, Villalobos-Cerrud D, Fabrega L, Montalvo JLS, Mendivil C, Quijada MR, Fernández-Pirla S, Wong D, de Guevara ML, Flores C, Borace J, García A, Caballero N, Rengifo-Herrera C, de Saez MTM, Restrepo CM, Llanes A, Guzman G, Villareal A, Perez A, Galvis CAN, Montes MV, Perez NIC, Garcia-López LL, Muñoz-Ortiz J, Rivera-Valdivia N, Bohorquez-Granados MC, de-la-Torre GC, Hernandez JDV, Celis-Giraldo D, Dávila JAA, Torres E, Oquendo MM, Arteaga-Rivera JY, Peyron F, Wallon M, Chapey E, Charter C, De Frias M, de-la-Torre A, Britton G, Motta J, Romero IL, Gómez-Marín J, Kosagisharaf JR, Llorens XS, Reyes O. Building Programs to Eradicate Toxoplasmosis Part IV: Understanding and Development of Public Health Strategies and Advances "Take a Village". Curr Pediatr Rep. 2022; 10(3):125-154. PMID: 35991908; PMCID: PMC9379243.
      Citations: 1     
    8. Wang K, Moreira A, Grose A, Leahy K, Zhou Y, Clouser FA, Siddiqui M, Leong N, Goodall P, Michalowski M, Ismail M, Christmas M, Schrantz S, Raggi C, Castro C, Moossazadeh D, Ramirez M, Pandey A, Ashi K, Dovgin S, Dixon A, Li X, Begeman I, Heichman S, Lykins J, Caballero N, Ross S, Dogra M, Dhamsania V, Graves N, Kirchberg M, Mathur K, Aue A, Boyer K, Heydemann P, Noble AG, Swisher C, Rabiah P, Withers S, Hull T, Frim D, McLone D, Su C, Blair M, Latkany P, Mui E, Vasconcelos-Santos DV, Ramirez M, Chittenden C, Wang E, Hernandez JDV, Nicolae DL, Rzhetsky A, Roizen N, Stillwaggon E, Sawers L, Montoya J, Press C, Ramirez R, Contopoulos-Ioannidis D, Maldonado Y, Liesenfeld O, Gomez C, Wheeler K, Zehar S, McAuley J, Limonne D, Houze S, Abraham S, Piarroux R, Tesic V, Beavis K, Abeleda A, Sautter M, El Mansouri B, El Bachir A, Amarir F, El Bissati K, Holfels E, Penn R, Cohen W, Meier P, Grigg M, Felín MS, Caballero Z, Norero X, Estripeaut D, Ellis D, Rengifo-Herrera C, Villalobos-Cerrud D, Fabrega L, Montalvo JLS, Mendivil C, Quijada MR, Fernández-Pirla S, de La Guardia V, Wong D, de Guevara ML, Flores C, Borace J, García A, de Saez MTM, Politis M, Restrepo CM, Llanes A, Guzman G, Rebellon A, Villareal A, Perez A, Galvis CAN, Montes MV, Perez NIC, Garcia-López LL, Muñoz-Ortiz J, Rivera-Valdivia N, Bohorquez-Granados MC, de-la-Torre GC, Padrieu G, Celis-Giraldo D, Dávila JAA, Torres E, Oquendo MM, Arteaga-Rivera JY, Peyron F, Wallon M, Chapey E, Levigne P, Charter C, De Frias M, de-la-Torre A, Britton G, Motta J, Ortega-Barria E, Romero IL, Gómez-Marín J, Kosagisharaf JR, Llorens XS, Reyes O, McLeod R. Building Programs to Eradicate Toxoplasmosis Part II: Education. Curr Pediatr Rep. 2022 Sep; 10(3):93-108. PMID: 36969368; PMCID: PMC10035399.
      Citations:    
    9. Felín MS, Wang K, Raggi C, Moreira A, Pandey A, Grose A, Caballero Z, Rengifo-Herrera C, Ramirez M, Moossazadeh D, Castro C, Montalvo JLS, Leahy K, Zhou Y, Clouser FA, Siddiqui M, Leong N, Goodall P, Michalowski M, Ismail M, Christmas M, Schrantz S, Norero X, Estripeaut D, Ellis D, Ashi K, Dovgin S, Dixon A, Li X, Begeman I, Heichman S, Lykins J, Villalobos-Cerrud D, Fabrega L, Mendivil C, Quijada MR, Fernández-Pirla S, de La Guardia V, Wong D, de LadrónGuevara M, Flores C, Borace J, García A, Caballero N, de Saez MTM, Politis M, Ross S, Dogra M, Dhamsania V, Graves N, Kirchberg M, Mathur K, Aue A, Restrepo CM, Llanes A, Guzman G, Rebollon A, Boyer K, Heydemann P, Noble AG, Swisher C, Rabiah P, Withers S, Hull T, Su C, Blair M, Latkany P, Mui E, Vasconcelos-Santos DV, Villareal A, Perez A, Galvis CAN, Montes MV, Perez NIC, Ramirez M, Chittenden C, Wang E, Garcia-López LL, Muñoz-Ortiz J, Rivera-Valdivia N, Bohorquez-Granados MC, de-la-Torre GC, Padrieu G, Hernandez JDV, Celis-Giraldo D, Acosta Dávila JA, Torres E, Oquendo MM, Arteaga-Rivera JY, Nicolae D, Rzhetsky A, Roizen N, Stillwaggon E, Sawers L, Peyron F, Wallon M, Chapey E, Levigne P, Charter C, De Frias M, Montoya J, Press C, Ramirez R, Contopoulos-Ioannidis D, Maldonado Y, Liesenfeld O, Gomez C, Wheeler K, Holfels E, Frim D, McLone D, Penn R, Cohen W, Zehar S, McAuley J, Limonne D, Houze S, Abraham S, Piarroux R, Tesic V, Beavis K, Abeleda A, Sautter M, El Mansouri B, El Bachir A, Amarir F, El Bissati K, de-la-Torre A, Britton G, Motta J, Ortega-Barria E, Romero IL, Meier P, Grigg M, Gómez-Marín J, Kosagisharaf JR, Llorens XS, Reyes O, McLeod R. Building Programs to Eradicate Toxoplasmosis Part III: Epidemiology and Risk Factors. Curr Pediatr Rep. 2022 Sep; 10(3):109-124. PMID: 37744780; PMCID: PMC10516319.
      Citations:    
    10. Shi C, Babiker N, Urbanek JK, Grossman RL, Huisingh-Scheetz M, Rzhetsky A. Free-living wrist and hip accelerometry forecast cognitive decline among older adults without dementia over 1- or 5-years in two distinct observational cohorts. NPJ Aging. 2022 Jun 06; 8(1):7. PMID: 35927250; PMCID: PMC9170733.
      Citations:    
    11. Zhang H, Khan A, Kushner SA, Rzhetsky A. Dissecting schizophrenia phenotypic variation: the contribution of genetic variation, environmental exposures, and gene-environment interactions. Schizophrenia (Heidelb). 2022 May 10; 8(1):51. PMID: 35853906; PMCID: PMC9261082.
      Citations: 1     
    12. Roper K, Abdel-Rehim A, Hubbard S, Carpenter M, Rzhetsky A, Soldatova L, King RD. Testing the reproducibility and robustness of the cancer biology literature by robot. J R Soc Interface. 2022 04; 19(189):20210821. PMID: 35382578; PMCID: PMC8984295.
      Citations:    Fields:    Translation:Humans
    13. Rivelli A, Fitzpatrick V, Chaudhari S, Chicoine L, Jia G, Rzhetsky A, Chicoine B. Prevalence of Mental Health Conditions Among 6078 Individuals With Down Syndrome in the United States. J Patient Cent Res Rev. 2022; 9(1):58-63. PMID: 35111883; PMCID: PMC8772605.
      Citations: 3     
    14. Fitzpatrick V, Rivelli A, Chaudhari S, Chicoine L, Jia G, Rzhetsky A, Chicoine B. Prevalence of Infectious Diseases Among 6078 Individuals With Down Syndrome in the United States. J Patient Cent Res Rev. 2022; 9(1):64-69. PMID: 35111884; PMCID: PMC8772611.
      Citations: 2     
    15. Rivelli A, Fitzpatrick V, Wales D, Chicoine L, Jia G, Rzhetsky A, Chicoine B. Prevalence of Endocrine Disorders Among 6078 Individuals With Down Syndrome in the United States. J Patient Cent Res Rev. 2022; 9(1):70-74. PMID: 35111885; PMCID: PMC8772613.
      Citations: 6     
    16. Hogan PG, Parrish KL, Mork RL, Boyle MG, Muenks CE, Thompson RM, Morelli JJ, Sullivan ML, Hunstad DA, Bubeck Wardenburg J, Rzhetsky A, Gehlert SJ, Burnham CD, Fritz SA. HOME2 Study: Household Versus Personalized Decolonization in Households of Children With Methicillin-Resistant Staphylococcus aureus Skin and Soft Tissue Infection-A Randomized Clinical Trial. Clin Infect Dis. 2021 12 06; 73(11):e4568-e4577. PMID: 32521007; PMCID: PMC8653631.
      Citations: 7     Fields:    Translation:HumansCells
    17. Long Y, Chen Q, Larsson H, Rzhetsky A. Observable variations in human sex ratio at birth. PLoS Comput Biol. 2021 12; 17(12):e1009586. PMID: 34855745; PMCID: PMC8638995.
      Citations: 3     Fields:    Translation:HumansPHPublic Health
    18. Bi J, Khan A, Tang J, Armando AM, Wu S, Zhang W, Gimple RC, Reed A, Jing H, Koga T, Wong IT, Gu Y, Miki S, Yang H, Prager B, Curtis EJ, Wainwright DA, Furnari FB, Rich JN, Cloughesy TF, Kornblum HI, Quehenberger O, Rzhetsky A, Cravatt BF, Mischel PS. Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug. Cell Rep. 2021 11 02; 37(5):109957. PMID: 34731610; PMCID: PMC8856626.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    19. Wang K, Stevens R, Li Y, Soldatova L, King R, Ananiadou S, Schoene AM, Li M, Christopoulou F, Matthew J, Garg S, Hermjakob U, Marcu D, Sheng E, Galstyan A, Gao X, Chambers B, Pan W, Khomtchouk BB, Evans JA, Rzhetsky A, Alachram H, Ambite JL, Beißbarth T, Wingender E. NERO: a biomedical named-entity (recognition) ontology with a large, annotated corpus reveals meaningful associations through text embedding. NPJ Syst Biol Appl. 2021 10 20; 7(1):38. PMID: 34671039; PMCID: PMC8528865.
      Citations:    Fields:    
    20. Chattopadhyay I, Boxx GM, Fraley ER, Silva TK, Zhou M, Phan M, Herrera I, Taloma S, Mandanas R, Bach K, Gandal M, Geschwind DH, Cheng G, Rzhetsky A, White SA, Silva AJ, López-Aranda MF. Postnatal immune activation causes social deficits in a mouse model of tuberous sclerosis: Role of microglia and clinical implications. Sci Adv. 2021 Sep 17; 7(38):eabf2073. PMID: 34533985; PMCID: PMC8448451.
      Citations: 6     Fields:    
    21. Zhang H, Khan A, Chen Q, Larsson H, Rzhetsky A. Do psychiatric diseases follow annual cyclic seasonality? PLoS Biol. 2021 07; 19(7):e3001347. PMID: 34280189; PMCID: PMC8345894.
      Citations: 6     Fields:    Translation:Humans
    22. Chicoine B, Rivelli A, Fitzpatrick V, Chicoine L, Jia G, Rzhetsky A. Prevalence of Common Disease Conditions in a Large Cohort of Individuals With Down Syndrome in the United States. J Patient Cent Res Rev. 2021; 8(2):86-97. PMID: 33898640; PMCID: PMC8060042.
      Citations: 14     
    23. Schuster B, Junkin M, Kashaf SS, Romero-Calvo I, Kirby K, Matthews J, Weber CR, Rzhetsky A, White KP, Tay S. Automated microfluidic platform for dynamic and combinatorial drug screening of tumor organoids. Nat Commun. 2020 10 19; 11(1):5271. PMID: 33077832; PMCID: PMC7573629.
      Citations: 68     Fields:    Translation:Humans
    24. Zhang H, Khan A, Edgren G, Rzhetsky A, Dahlén T. Measurable health effects associated with the daylight saving time shift. PLoS Comput Biol. 2020 06; 16(6):e1007927. PMID: 32511231; PMCID: PMC7302868.
      Citations: 4     Fields:    Translation:Humans
    25. Hogan PG, Mork RL, Thompson RM, Muenks CE, Boyle MG, Sullivan ML, Morelli JJ, Williams CV, Sanchez N, Hunstad DA, Wardenburg JB, Gehlert SJ, Burnham CD, Rzhetsky A, Fritz SA. Environmental Methicillin-resistant Staphylococcus aureus Contamination, Persistent Colonization, and Subsequent Skin and Soft Tissue Infection. JAMA Pediatr. 2020 06 01; 174(6):552-562. PMID: 32227144; PMCID: PMC7105954.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    26. Zhong X, Yin Z, Jia G, Zhou D, Wei Q, Faucon A, Evans P, Gamazon ER, Li B, Tao R, Rzhetsky A, Bastarache L, Cox NJ. Electronic health record phenotypes associated with genetically regulated expression of CFTR and application to cystic fibrosis. Genet Med. 2020 07; 22(7):1191-1200. PMID: 32296164; PMCID: PMC7781195.
      Citations: 6     Fields:    Translation:Humans
    27. Jia G, Li Y, Zhang H, Chattopadhyay I, Boeck Jensen A, Blair DR, Davis L, Robinson PN, Benson M, Edgren G, Cox NJ, Gao X, Rzhetsky A, Dahlén T, Brunak S. Estimating heritability and genetic correlations from large health datasets in the absence of genetic data. Nat Commun. 2019 12 03; 10(1):5508. PMID: 31796735; PMCID: PMC6890770.
      Citations: 8     Fields:    Translation:Humans
    28. Mork RL, Hogan PG, Muenks CE, Boyle MG, Thompson RM, Sullivan ML, Morelli JJ, Seigel J, Orscheln RC, Bubeck Wardenburg J, Gehlert SJ, Burnham CD, Rzhetsky A, Fritz SA. Longitudinal, strain-specific Staphylococcus aureus introduction and transmission events in households of children with community-associated meticillin-resistant S aureus skin and soft tissue infection: a prospective cohort study. Lancet Infect Dis. 2020 02; 20(2):188-198. PMID: 31784369; PMCID: PMC6995751.
      Citations: 25     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    29. Khan A, Plana-Ripoll O, Antonsen S, Geels C, Landecker H, Sullivan PF, Rzhetsky A, Brandt J, Pedersen CB. Environmental pollution is associated with increased risk of psychiatric disorders in the US and Denmark. PLoS Biol. 2019 08; 17(8):e3000353. PMID: 31430271; PMCID: PMC6701746.
      Citations: 38     Fields:    Translation:HumansPHPublic Health
    30. Danchev V, Rzhetsky A, Evans JA. Centralized scientific communities are less likely to generate replicable results. Elife. 2019 07 02; 8. PMID: 31264964; PMCID: PMC6606034.
      Citations: 6     Fields:    Translation:Humans
    31. Zhang C, Tu HL, Jia G, Mukhtar T, Taylor V, Rzhetsky A, Tay S. Ultra-multiplexed analysis of single-cell dynamics reveals logic rules in differentiation. Sci Adv. 2019 04; 5(4):eaav7959. PMID: 30949582; PMCID: PMC6447378.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    32. Unlu G, Gamazon ER, Qi X, Levic DS, Bastarache L, Denny JC, Roden DM, Mayzus I, Breyer M, Zhong X, Konkashbaev AI, Rzhetsky A, Knapik EW, Cox NJ. GRIK5 Genetically Regulated Expression Associated with Eye and Vascular Phenomes: Discovery through Iteration among Biobanks, Electronic Health Records, and Zebrafish. Am J Hum Genet. 2019 03 07; 104(3):503-519. PMID: 30827500; PMCID: PMC6407495.
      Citations: 11     Fields:    Translation:HumansAnimals
    33. Hogan PG, Mork RL, Boyle MG, Muenks CE, Morelli JJ, Thompson RM, Sullivan ML, Gehlert SJ, Merlo JR, McKenzie MG, Wardenburg JB, Rzhetsky A, Burnham CD, Fritz SA. Interplay of personal, pet, and environmental colonization in households affected by community-associated methicillin-resistant Staphylococcus aureus. J Infect. 2019 03; 78(3):200-207. PMID: 30503843; PMCID: PMC6408279.
      Citations: 19     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    34. Leypunskiy E, Kiciman E, Shah M, Walch OJ, Rzhetsky A, Dinner AR, Rust MJ. Geographically Resolved Rhythms in Twitter Use Reveal Social Pressures on Daily Activity Patterns. Curr Biol. 2018 12 03; 28(23):3763-3775.e5. PMID: 30449672; PMCID: PMC6590897.
      Citations: 8     Fields:    Translation:Humans
    35. Melamed RD, Rzhetsky A. Patchwork of contrasting medication cultures across the USA. Nat Commun. 2018 10 09; 9(1):4022. PMID: 30301884; PMCID: PMC6177425.
      Citations: 2     Fields:    Translation:Humans
    36. Romero-Calvo I, Weber CR, Ray M, Brown M, Kirby K, Nandi RK, Long TM, Sparrow SM, Ugolkov A, Qiang W, Zhang Y, Brunetti T, Kindler H, Segal JP, Rzhetsky A, Mazar AP, Buschmann MM, Weichselbaum R, Roggin K, White KP. Human Organoids Share Structural and Genetic Features with Primary Pancreatic Adenocarcinoma Tumors. Mol Cancer Res. 2019 01; 17(1):70-83. PMID: 30171177; PMCID: PMC6647028.
      Citations: 49     Fields:    Translation:HumansAnimals
    37. Mork RL, Hogan PG, Muenks CE, Boyle MG, Thompson RM, Morelli JJ, Sullivan ML, Gehlert SJ, Ross DG, Yn A, Bubeck Wardenburg J, Rzhetsky A, Burnham CD, Fritz SA. Comprehensive modeling reveals proximity, seasonality, and hygiene practices as key determinants of MRSA colonization in exposed households. Pediatr Res. 2018 11; 84(5):668-676. PMID: 30135590; PMCID: PMC6294678.
      Citations: 13     Fields:    Translation:HumansCellsPHPublic Health
    38. Gray CL, Lobdell DT, Rappazzo KM, Jian Y, Jagai JS, Messer LC, Patel AP, DeFlorio-Barker SA, Lyttle C, Solway J, Rzhetsky A. Associations between environmental quality and adult asthma prevalence in medical claims data. Environ Res. 2018 10; 166:529-536. PMID: 29957506; PMCID: PMC6110955.
      Citations: 6     Fields:    Translation:Humans
    39. Kim JS, Gao X, Rzhetsky A. RIDDLE: Race and ethnicity Imputation from Disease history with Deep LEarning. PLoS Comput Biol. 2018 04; 14(4):e1006106. PMID: 29698408; PMCID: PMC5940243.
      Citations: 5     Fields:    Translation:Humans
    40. Chattopadhyay I, Kiciman E, Elliott JW, Shaman JL, Rzhetsky A. Conjunction of factors triggering waves of seasonal influenza. Elife. 2018 02 27; 7. PMID: 29485041; PMCID: PMC5864297.
      Citations: 20     Fields:    Translation:HumansCellsPHPublic Health
    41. Krishack PA, Wang K, Rzhetsky A, Solway J, Sperling AI, Verhoef PA. Preexisting Type 2 Immune Activation Protects against the Development of Sepsis. Am J Respir Cell Mol Biol. 2017 11; 57(5):628-630. PMID: 29090959; PMCID: PMC5705910.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    42. Wang K, Gaitsch H, Poon H, Cox NJ, Rzhetsky A. Classification of common human diseases derived from shared genetic and environmental determinants. Nat Genet. 2017 Sep; 49(9):1319-1325. PMID: 28783162; PMCID: PMC5577363.
      Citations: 85     Fields:    Translation:Humans
    43. Lykins J, Wang K, Wheeler K, Clouser F, Dixon A, El Bissati K, Zhou Y, Lyttle C, Rzhetsky A, McLeod R. Understanding Toxoplasmosis in the United States Through "Large Data" Analyses. Clin Infect Dis. 2016 08 15; 63(4):468-75. PMID: 27353665; PMCID: PMC4967610.
      Citations: 22     Fields:    Translation:Humans
    44. Rzhetsky A, Foster JG, Foster IT, Evans JA. Choosing experiments to accelerate collective discovery. Proc Natl Acad Sci U S A. 2015 Nov 24; 112(47):14569-74. PMID: 26554009; PMCID: PMC4664375.
      Citations: 41     Fields:    Translation:Humans
    45. Yao L, Li Y, Ghosh S, Evans JA, Rzhetsky A. Health ROI as a measure of misalignment of biomedical needs and resources. Nat Biotechnol. 2015 08; 33(8):807-11. PMID: 26252133; PMCID: PMC5843469.
      Citations: 9     Fields:    Translation:Humans
    46. Melamed RD, Emmett KJ, Madubata C, Rzhetsky A, Rabadan R. Genetic similarity between cancers and comorbid Mendelian diseases identifies candidate driver genes. Nat Commun. 2015 Apr 30; 6:7033. PMID: 25926297; PMCID: PMC4416231.
      Citations: 21     Fields:    Translation:Humans
    47. Blair DR, Wang K, Nestorov S, Evans JA, Rzhetsky A. Quantifying the impact and extent of undocumented biomedical synonymy. PLoS Comput Biol. 2014 Sep; 10(9):e1003799. PMID: 25255227; PMCID: PMC4177665.
      Citations: 5     Fields:    Translation:Humans
    48. Liu CC, Tseng YT, Li W, Wu CY, Mayzus I, Rzhetsky A, Sun F, Waterman M, Chen JJ, Chaudhary PM, Loscalzo J, Crandall E, Zhou XJ. DiseaseConnect: a comprehensive web server for mechanism-based disease-disease connections. Nucleic Acids Res. 2014 Jul; 42(Web Server issue):W137-46. PMID: 24895436; PMCID: PMC4086092.
      Citations: 52     Fields:    Translation:Humans
    49. Rzhetsky A, Bagley SC, Wang K, Lyttle CS, Cook EH, Altman RB, Gibbons RD. Environmental and state-level regulatory factors affect the incidence of autism and intellectual disability. PLoS Comput Biol. 2014 Mar; 10(3):e1003518. PMID: 24625521; PMCID: PMC3952819.
      Citations: 17     Fields:    Translation:Humans
    50. Maltsev N, Rzhetsky A, Conrad Gilliam T. Systems analysis of human multigene disorders. Preface. Adv Exp Med Biol. 2014; 799:v - viii. PMID: 24678533.
      Citations: 2     Fields:    Translation:Humans
    51. Blair DR, Lyttle CS, Mortensen JM, Bearden CF, Jensen AB, Khiabanian H, Melamed R, Rabadan R, Bernstam EV, Jensen LJ, Nicolae D, Shah NH, Grossman RL, Cox NJ, White KP, Rzhetsky A, Brunak S. A nondegenerate code of deleterious variants in Mendelian loci contributes to complex disease risk. Cell. 2013 Sep 26; 155(1):70-80. PMID: 24074861; PMCID: PMC3844554.
      Citations: 127     Fields:    Translation:Humans
    52. Soldatova LN, Rzhetsky A, De Grave K, King RD. Representation of probabilistic scientific knowledge. J Biomed Semantics. 2013 Apr 15; 4 Suppl 1:S7. PMID: 23734675; PMCID: PMC3632998.
      Citations: 7     Fields:    
    53. Balkir AS, Foster I, Rzhetsky A. A Distributed Look-up Architecture for Text Mining Applications using MapReduce. Proc Int Symp High Perform Distrib Comput. 2011 Nov; 2011. PMID: 25356441; PMCID: PMC4209700.
      Citations:    
    54. Divoli A, Evans JA, Rzhetsky A, Mendonça EA. Conflicting biomedical assumptions for mathematical modeling: the case of cancer metastasis. PLoS Comput Biol. 2011 Oct; 7(10):e1002132. PMID: 21998558; PMCID: PMC3188482.
      Citations: 6     Fields:    Translation:Humans
    55. Rzhetsky A, Evans JA. War of ontology worlds: mathematics, computer code, or Esperanto? PLoS Comput Biol. 2011 Sep; 7(9):e1002191. PMID: 21980276; PMCID: PMC3182873.
      Citations: 3     Fields:    Translation:Humans
    56. Soldatova LN, Rzhetsky A. Representation of research hypotheses. J Biomed Semantics. 2011 May 17; 2 Suppl 2:S9. PMID: 21624164; PMCID: PMC3102898.
      Citations: 7     Fields:    
    57. Evans JA, Rzhetsky A. Advancing science through mining libraries, ontologies, and communities. J Biol Chem. 2011 Jul 08; 286(27):23659-66. PMID: 21566119; PMCID: PMC3129146.
      Citations: 9     Fields:    Translation:HumansAnimals
    58. Yao L, Divoli A, Mayzus I, Evans JA, Rzhetsky A. Benchmarking ontologies: bigger or better? PLoS Comput Biol. 2011 Jan 13; 7(1):e1001055. PMID: 21249231; PMCID: PMC3020923.
      Citations: 8     Fields:    
    59. Demir E, Cary MP, Paley S, Fukuda K, Lemer C, Vastrik I, Wu G, D'Eustachio P, Schaefer C, Luciano J, Schacherer F, Martinez-Flores I, Hu Z, Jimenez-Jacinto V, Joshi-Tope G, Kandasamy K, Lopez-Fuentes AC, Mi H, Pichler E, Rodchenkov I, Splendiani A, Tkachev S, Zucker J, Gopinath G, Rajasimha H, Ramakrishnan R, Shah I, Syed M, Anwar N, Blinov M, Brauner E, Corwin D, Donaldson S, Gibbons F, Goldberg R, Hornbeck P, Luna A, Murray-Rust P, Neumann E, Ruebenacker O, Reubenacker O, Samwald M, van Iersel M, Wimalaratne S, Allen K, Braun B, Whirl-Carrillo M, Cheung KH, Dahlquist K, Finney A, Gillespie M, Glass E, Gong L, Haw R, Honig M, Hubaut O, Kane D, Krupa S, Kutmon M, Leonard J, Marks D, Merberg D, Petri V, Pico A, Ravenscroft D, Ren L, Shah N, Sunshine M, Tang R, Whaley R, Letovksy S, Buetow KH, Rzhetsky A, Schachter V, Sobral BS, Dogrusoz U, McWeeney S, Aladjem M, Birney E, Collado-Vides J, Goto S, Hucka M, Maltsev N, Pandey A, Thomas P, Wingender E, Karp PD, Sander C, Bader GD, Babur O, Le Novère N. The BioPAX community standard for pathway data sharing. Nat Biotechnol. 2010 Sep; 28(9):935-42. PMID: 20829833; PMCID: PMC3001121.
      Citations: 330     Fields:    Translation:Cells
    60. Evans J, Rzhetsky A. Philosophy of science. Machine science. Science. 2010 Jul 23; 329(5990):399-400. PMID: 20651141; PMCID: PMC3647224.
      Citations: 12     Fields:    
    61. Yao L, Evans JA, Rzhetsky A. Novel opportunities for computational biology and sociology in drug discovery. Trends Biotechnol. 2010 Apr; 28(4):161-70. PMID: 20349528; PMCID: PMC3654551.
      Citations: 10     Fields:    Translation:Humans
    62. Yao L, Evans JA, Rzhetsky A. WITHDRAWN: Novel opportunities for computational biology and sociology in drug discovery. Trends Biotechnol. 2010 Feb 05. PMID: 26642912.
      Citations:    Fields:    
    63. Iossifov I, Rodriguez-Esteban R, Mayzus I, Millen KJ, Rzhetsky A. Looking at cerebellar malformations through text-mined interactomes of mice and humans. PLoS Comput Biol. 2009 Nov; 5(11):e1000559. PMID: 19893633; PMCID: PMC2767227.
      Citations: 12     Fields:    Translation:HumansAnimals
    64. Yao L, Evans JA, Rzhetsky A. Novel opportunities for computational biology and sociology in drug discovery. Trends Biotechnol. 2009 Sep; 27(9):531-40. PMID: 19674801; PMCID: PMC2761076.
      Citations: 2     Fields:    Translation:Humans
    65. Rzhetsky A, Seringhaus M, Gerstein MB. Getting started in text mining: part two. PLoS Comput Biol. 2009 Jul; 5(7):e1000411. PMID: 19649304; PMCID: PMC2709911.
      Citations: 12     Fields:    
    66. Rzhetsky A, Shatkay H, Wilbur WJ. How to get the most out of your curation effort. PLoS Comput Biol. 2009 May; 5(5):e1000391. PMID: 19461884; PMCID: PMC2678295.
      Citations: 8     Fields:    
    67. Liu J, Ghanim M, Xue L, Brown CD, Iossifov I, Angeletti C, Hua S, Ludwig M, Stricker T, Al-Ahmadie HA, Tretiakova M, Camp RL, Perera-Alberto M, Rimm DL, Xu T, Rzhetsky A, White KP, Nègre N. Analysis of Drosophila segmentation network identifies a JNK pathway factor overexpressed in kidney cancer. Science. 2009 Feb 27; 323(5918):1218-22. PMID: 19164706; PMCID: PMC2756524.
      Citations: 68     Fields:    Translation:HumansAnimalsCells
    68. Shatkay H, Pan F, Rzhetsky A, Wilbur WJ. Multi-dimensional classification of biomedical text: toward automated, practical provision of high-utility text to diverse users. Bioinformatics. 2008 Sep 15; 24(18):2086-93. PMID: 18718948; PMCID: PMC2530883.
      Citations: 32     Fields:    
    69. Rzhetsky A, Seringhaus M, Gerstein M. Seeking a new biology through text mining. Cell. 2008 Jul 11; 134(1):9-13. PMID: 18614002; PMCID: PMC2735884.
      Citations: 31     Fields:    
    70. Iossifov I, Zheng T, Baron M, Gilliam TC, Rzhetsky A. Genetic-linkage mapping of complex hereditary disorders to a whole-genome molecular-interaction network. Genome Res. 2008 Jul; 18(7):1150-62. PMID: 18417725; PMCID: PMC2493404.
      Citations: 36     Fields:    Translation:Humans
    71. Feldman I, Rzhetsky A, Vitkup D. Network properties of genes harboring inherited disease mutations. Proc Natl Acad Sci U S A. 2008 Mar 18; 105(11):4323-8. PMID: 18326631; PMCID: PMC2393821.
      Citations: 139     Fields:    Translation:Humans
    72. Rodriguez-Esteban R, Rzhetsky A. Six senses in the literature. The bleak sensory landscape of biomedical texts. EMBO Rep. 2008 Mar; 9(3):212-5. PMID: 18311168; PMCID: PMC2267391.
      Citations: 1     Fields:    Translation:Humans
    73. Yao L, Rzhetsky A. Quantitative systems-level determinants of human genes targeted by successful drugs. Genome Res. 2008 Feb; 18(2):206-13. PMID: 18083776; PMCID: PMC2203618.
      Citations: 31     Fields:    Translation:Humans
    74. Rzhetsky A, Wajngurt D, Park N, Zheng T. Probing genetic overlap among complex human phenotypes. Proc Natl Acad Sci U S A. 2007 Jul 10; 104(28):11694-9. PMID: 17609372; PMCID: PMC1906727.
      Citations: 147     Fields:    Translation:Humans
    75. Cokol M, Iossifov I, Rodriguez-Esteban R, Rzhetsky A. How many scientific papers should be retracted? EMBO Rep. 2007 May; 8(5):422-3. PMID: 17471252; PMCID: PMC1866214.
      Citations: 24     Fields:    
    76. Cokol M, Rodriguez-Esteban R, Rzhetsky A. A recipe for high impact. Genome Biol. 2007; 8(5):406. PMID: 17493291; PMCID: PMC1929134.
      Citations: 2     Fields:    
    77. Rzhetsky A, Zheng T, Weinreb C. Self-correcting maps of molecular pathways. PLoS One. 2006 Dec 20; 1:e61. PMID: 17183692; PMCID: PMC1762305.
      Citations: 5     Fields:    Translation:Humans
    78. Rodriguez-Esteban R, Iossifov I, Rzhetsky A. Imitating manual curation of text-mined facts in biomedicine. PLoS Comput Biol. 2006 Sep 08; 2(9):e118. PMID: 16965176; PMCID: PMC1560402.
      Citations: 12     Fields:    
    79. Wilbur WJ, Rzhetsky A, Shatkay H. New directions in biomedical text annotation: definitions, guidelines and corpus construction. BMC Bioinformatics. 2006 Jul 25; 7:356. PMID: 16867190; PMCID: PMC1559725.
      Citations: 48     Fields:    
    80. Rzhetsky A, Iossifov I, Loh JM, White KP. Microparadigms: chains of collective reasoning in publications about molecular interactions. Proc Natl Acad Sci U S A. 2006 Mar 28; 103(13):4940-5. PMID: 16543380; PMCID: PMC1402650.
      Citations: 22     Fields:    
    81. Cokol M, Iossifov I, Weinreb C, Rzhetsky A. Emergent behavior of growing knowledge about molecular interactions. Nat Biotechnol. 2005 Oct; 23(10):1243-7. PMID: 16211067.
      Citations: 22     Fields:    Translation:Cells
    82. Rzhetsky A, Fitch WM. Listening to viral tongues: comparing viral trees using a stochastic context-free grammar. Mol Biol Evol. 2005 Apr; 22(4):905-13. PMID: 15626684.
      Citations: 1     Fields:    Translation:Cells
    83. Krauthammer M, Kaufmann CA, Gilliam TC, Rzhetsky A. Molecular triangulation: bridging linkage and molecular-network information for identifying candidate genes in Alzheimer's disease. Proc Natl Acad Sci U S A. 2004 Oct 19; 101(42):15148-53. PMID: 15471992; PMCID: PMC523448.
      Citations: 66     Fields:    Translation:Humans
    84. Chien M, Morozova I, Shi S, Sheng H, Chen J, Gomez SM, Asamani G, Hill K, Nuara J, Feder M, Rineer J, Greenberg JJ, Steshenko V, Park SH, Zhao B, Teplitskaya E, Edwards JR, Pampou S, Georghiou A, Chou IC, Iannuccilli W, Ulz ME, Kim DH, Geringer-Sameth A, Goldsberry C, Morozov P, Fischer SG, Segal G, Qu X, Rzhetsky A, Zhang P, Cayanis E, De Jong PJ, Ju J, Kalachikov S, Shuman HA, Russo JJ. The genomic sequence of the accidental pathogen Legionella pneumophila. Science. 2004 Sep 24; 305(5692):1966-8. PMID: 15448271.
      Citations: 228     Fields:    Translation:Cells
    85. Iossifov I, Krauthammer M, Friedman C, Hatzivassiloglou V, Bader JS, White KP, Rzhetsky A. Probabilistic inference of molecular networks from noisy data sources. Bioinformatics. 2004 May 22; 20(8):1205-13. PMID: 14871876.
      Citations: 5     Fields:    Translation:AnimalsCells
    86. Rzhetsky A, Iossifov I, Koike T, Krauthammer M, Kra P, Morris M, Yu H, Weng W, Wilbur WJ, Hatzivassiloglou V, Friedman C, Duboué PA. GeneWays: a system for extracting, analyzing, visualizing, and integrating molecular pathway data. J Biomed Inform. 2004 Feb; 37(1):43-53. PMID: 15016385.
      Citations: 87     Fields:    Translation:Cells
    87. Noble WS, Rzhetsky A, Gomez SM. Learning to predict protein-protein interactions from protein sequences. Bioinformatics. 2003 Oct 12; 19(15):1875-81. PMID: 14555619.
      Citations: 51     Fields:    Translation:Cells
    88. Holm I, Graille M, Dehoux P, Rzhetsky A, Wincker P, Weissenbach J, Brey PT, Roth CW. Identification of the Anopheles gambiae ATP-binding cassette transporter superfamily genes. Mol Cells. 2003 Apr 30; 15(2):150-8. PMID: 12803476.
      Citations: 29     Fields:    Translation:HumansAnimals
    89. Karev GP, Wolf YI, Rzhetsky AY, Berezovskaya FS, Koonin EV, Karev GP, Wolf YI, Rzhetsky AY, Berezovskaya FS, Koonin EV. Birth and death of protein domains: a simple model of evolution explains power law behavior. BMC Evol Biol. 2002 Oct 14; 2:18. PMID: 12379152; PMCID: PMC137606.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    90. Christophides GK, Zdobnov E, Barillas-Mury C, Birney E, Blandin S, Blass C, Brey PT, Collins FH, Danielli A, Dimopoulos G, Hetru C, Hoa NT, Hoffmann JA, Kanzok SM, Letunic I, Levashina EA, Loukeris TG, Lycett G, Meister S, Michel K, Moita LF, Osta MA, Paskewitz SM, Reichhart JM, Rzhetsky A, Troxler L, Vernick KD, Vlachou D, Volz J, von Mering C, Xu J, Zheng L, Bork P, Kafatos FC, Christophides GK, Zdobnov E, Barillas-Mury C, Birney E, Blandin S, Blass C, Brey PT, Collins FH, Danielli A, Dimopoulos G, Hetru C, Hoa NT, Hoffmann JA, Kanzok SM, Letunic I, Levashina EA, Loukeris TG, Lycett G, Meister S, Michel K, Moita LF, Osta MA, Paskewitz SM, Reichhart JM, Rzhetsky A, Troxler L, Vernick KD, Vlachou D, Volz J, von Mering C, Xu J, Zheng L, Bork P, Kafatos FC. Immunity-related genes and gene families in Anopheles gambiae. Science. 2002 Oct 04; 298(5591):159-65. PMID: 12364793.
      Citations: 313     Fields:    Translation:AnimalsCells
    91. Yu H, Hatzivassiloglou V, Rzhetsky A, Wilbur WJ. Automatically identifying gene/protein terms in MEDLINE abstracts. J Biomed Inform. 2002 Oct-Dec; 35(5-6):322-30. PMID: 12968781.
      Citations: 5     Fields:    
    92. Friedman C, Kra P, Rzhetsky A. Two biomedical sublanguages: a description based on the theories of Zellig Harris. J Biomed Inform. 2002 Aug; 35(4):222-35. PMID: 12755517.
      Citations: 65     Fields:    
    93. Gomez SM, Rzhetsky A. Towards the prediction of complete protein--protein interaction networks. Pac Symp Biocomput. 2002; 413-24. PMID: 11928495.
      Citations: 15     Fields:    Translation:Cells
    94. Krauthammer M, Kra P, Iossifov I, Gomez SM, Hripcsak G, Hatzivassiloglou V, Friedman C, Rzhetsky A. Of truth and pathways: chasing bits of information through myriads of articles. Bioinformatics. 2002; 18 Suppl 1:S249-57. PMID: 12169554.
      Citations: 9     Fields:    Translation:Cells
    95. Yu H, Hatzivassiloglou V, Friedman C, Rzhetsky A, Wilbur WJ, Yu H, Hatzivassiloglou V, Friedman C, Rzhetsky A, Wilbur WJ. Automatic extraction of gene and protein synonyms from MEDLINE and journal articles. Proc AMIA Symp. 2002; 919-23. PMID: 12463959; PMCID: PMC2244511.
      Citations: 13     Fields:    
    96. Gomez SM, Lo SH, Rzhetsky A. Probabilistic prediction of unknown metabolic and signal-transduction networks. Genetics. 2001 Nov; 159(3):1291-8. PMID: 11729170; PMCID: PMC1461852.
      Citations: 10     Fields:    Translation:AnimalsCells
    97. Rzhetsky A, Gomez SM, Rzhetsky A, Gomez SM. Birth of scale-free molecular networks and the number of distinct DNA and protein domains per genome. Bioinformatics. 2001 Oct; 17(10):988-96. PMID: 11673244.
      Citations: 36     Fields:    Translation:Humans
    98. Tammur J, Prades C, Arnould I, Rzhetsky A, Hutchinson A, Adachi M, Schuetz JD, Swoboda KJ, Rosier M, Dean M, Allikmets R, Tammur J, Prades C, Arnould I, Rzhetsky A, Hutchinson A, Adachi M, Schuetz JD, Swoboda KJ, Rosier M, Dean M, Allikmets R. Two new genes from the human ATP-binding cassette transporter superfamily, ABCC11 and ABCC12, tandemly duplicated on chromosome 16q12. Gene. 2001 Jul 25; 273(1):89-96. PMID: 11483364.
      Citations: 35     Fields:    Translation:HumansCells
    99. Dean M, Rzhetsky A, Allikmets R. The human ATP-binding cassette (ABC) transporter superfamily. Genome Res. 2001 Jul; 11(7):1156-66. PMID: 11435397.
      Citations: 545     Fields:    Translation:HumansAnimals
    100. Scott K, Brady R, Cravchik A, Morozov P, Rzhetsky A, Zuker C, Axel R. A chemosensory gene family encoding candidate gustatory and olfactory receptors in Drosophila. Cell. 2001 Mar 09; 104(5):661-73. PMID: 11257221.
      Citations: 274     Fields:    Translation:AnimalsCells
    101. Rzhetsky A, Morozov P. Markov chain Monte Carlo computation of confidence intervals for substitution-rate variation in proteins. Pac Symp Biocomput. 2001; 203-14. PMID: 11262941.
      Citations: 1     Fields:    
    102. Friedman C, Kra P, Yu H, Krauthammer M, Rzhetsky A, Friedman C, Kra P, Yu H, Krauthammer M, Rzhetsky A. GENIES: a natural-language processing system for the extraction of molecular pathways from journal articles. Bioinformatics. 2001; 17 Suppl 1:S74-82. PMID: 11472995.
      Citations: 91     Fields:    
    103. Hatzivassiloglou V, Rzhetsky A, Hatzivassiloglou V, Rzhetsky A. Disambiguating proteins, genes, and RNA in text: a machine learning approach. Bioinformatics. 2001; 17 Suppl 1:S97-106. PMID: 11472998.
      Citations: 27     Fields:    
    104. Annilo T, Tammur J, Hutchinson A, Rzhetsky A, Dean M, Allikmets R. Human and mouse orthologs of a new ATP-binding cassette gene, ABCG4. Cytogenet Cell Genet. 2001; 94(3-4):196-201. PMID: 11856881.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    105. Koike T, Rzhetsky A. A graphic editor for analyzing signal-transduction pathways. Gene. 2000 Dec 23; 259(1-2):235-44. PMID: 11163981.
      Citations: 2     Fields:    Translation:HumansCells
    106. Krauthammer M, Rzhetsky A, Morozov P, Friedman C. Using BLAST for identifying gene and protein names in journal articles. Gene. 2000 Dec 23; 259(1-2):245-52. PMID: 11163982.
      Citations: 31     Fields:    Translation:Cells
    107. Rzhetsky A, Koike T, Kalachikov S, Gomez SM, Krauthammer M, Kaplan SH, Kra P, Russo JJ, Friedman C. A knowledge model for analysis and simulation of regulatory networks. Bioinformatics. 2000 Dec; 16(12):1120-8. PMID: 11159331.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    108. Tilson MD, Rzhetsky A. A novel hypothesis regarding the evolutionary origins of the immunoglobulin fold. Curr Med Res Opin. 2000; 16(2):88-93. PMID: 10893652.
      Citations: 3     Fields:    Translation:AnimalsCells
    109. Morozov P, Sitnikova T, Churchill G, Ayala FJ, Rzhetsky A. A new method for characterizing replacement rate variation in molecular sequences. Application of the Fourier and wavelet models to Drosophila and mammalian proteins. Genetics. 2000 Jan; 154(1):381-95. PMID: 10628997; PMCID: PMC1460898.
      Citations: 3     Fields:    Translation:HumansAnimals
    110. Migliazza A, Cayanis E, Bosch-Albareda F, Komatsu H, Martinotti S, Toniato E, Kalachikov S, Bonaldo MF, Jelene P, Ye X, Rzhetsky A, Qu X, Chien M, Inghirami G, Gaidano G, Vitolo U, Saglio G, Resegotti L, Zhang P, Soares MB, Russo J, Fischer SG, Edelman IS, Efstratiadis A, Dalla-Favera R. Molecular pathogenesis of B-cell chronic lymphocytic leukemia: analysis of 13q14 chromosomal deletions. Curr Top Microbiol Immunol. 2000; 252:275-84. PMID: 11125485.
      Citations: 3     Fields:    Translation:HumansCells
    111. Vosshall LB, Amrein H, Morozov PS, Rzhetsky A, Axel R. A spatial map of olfactory receptor expression in the Drosophila antenna. Cell. 1999 Mar 05; 96(5):725-36. PMID: 10089887.
      Citations: 381     Fields:    Translation:AnimalsCells
    112. Rzhetsky A, Kalachikov S, Ye X, Zhang P, Russo JJ. Tools for visualization and integration of intermediate sequencing results in large disease gene discovery projects. Gene. 1998 Feb 16; 208(1):31-5. PMID: 9479040.
      Citations:    Fields:    Translation:HumansCells
    113. Yoshida A, Rzhetsky A, Hsu LC, Chang C. Human aldehyde dehydrogenase gene family. Eur J Biochem. 1998 Feb 01; 251(3):549-57. PMID: 9490025.
      Citations: 143     Fields:    Translation:HumansAnimalsCells
    114. Ayala FJ, Rzhetsky A, Ayala FJ. Origin of the metazoan phyla: molecular clocks confirm paleontological estimates. Proc Natl Acad Sci U S A. 1998 Jan 20; 95(2):606-11. PMID: 9435239; PMCID: PMC18467.
      Citations: 52     Fields:    Translation:Animals
    115. Qu XY, Hauptschein RS, Rzhetsky A, Scotto L, Chien MC, Ye X, Frigeri F, Rao PH, Pasqualucci L, Gamberi B, Deaven LL, Zhang P, Chaganti RS, Dalla-Favera R, Russo JJ. Analysis of a 69-kb contiguous genomic sequence at a putative tumor suppressor gene locus on human chromosome 6q27. DNA Seq. 1998; 9(4):189-204. PMID: 10520750.
      Citations: 2     Fields:    Translation:HumansCells
    116. Rzhetsky A, Ayala FJ, Hsu LC, Chang C, Yoshida A. Exon/intron structure of aldehyde dehydrogenase genes supports the "introns-late" theory. Proc Natl Acad Sci U S A. 1997 Jun 24; 94(13):6820-5. PMID: 9192649; PMCID: PMC21242.
      Citations: 24     Fields:    Translation:HumansAnimals
    117. Rzhetsky A, Dopazo J, Snyder E, Dangler CA, Ayala FJ. Assessing dissimilarity of genes by comparing their RNAse A mismatch cleavage patterns. Genetics. 1996 Dec; 144(4):1975-83. PMID: 8978080; PMCID: PMC1207744.
      Citations:    Fields:    Translation:HumansAnimals
    118. Rzhetsky A, Sitnikova T. When is it safe to use an oversimplified substitution model in tree-making? Mol Biol Evol. 1996 Nov; 13(9):1255-65. PMID: 8896378.
      Citations: 4     Fields:    Translation:Cells
    119. Kumar S, Rzhetsky A. Evolutionary relationships of eukaryotic kingdoms. J Mol Evol. 1996 Feb; 42(2):183-93. PMID: 8919870.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    120. Rzhetsky A. Estimating substitution rates in ribosomal RNA genes. Genetics. 1995 Oct; 141(2):771-83. PMID: 8647409; PMCID: PMC1206772.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    121. Takezaki N, Rzhetsky A, Nei M. Phylogenetic test of the molecular clock and linearized trees. Mol Biol Evol. 1995 Sep; 12(5):823-33. PMID: 7476128.
      Citations: 181     Fields:    Translation:HumansAnimals
    122. Sitnikova T, Rzhetsky A, Nei M. Interior-branch and bootstrap tests of phylogenetic trees. Mol Biol Evol. 1995 Mar; 12(2):319-33. PMID: 7700156.
      Citations: 42     Fields:    
    123. Rzhetsky A, Nei M. Tests of applicability of several substitution models for DNA sequence data. Mol Biol Evol. 1995 Jan; 12(1):131-51. PMID: 7877488.
      Citations: 25     Fields:    Translation:Cells
    124. Rzhetsky A, Kumar S, Nei M. Four-cluster analysis: a simple method to test phylogenetic hypotheses. Mol Biol Evol. 1995 Jan; 12(1):163-7. PMID: 7877491.
      Citations: 12     Fields:    Translation:Animals
    125. Rzhetsky A, Nei M. METREE: a program package for inferring and testing minimum-evolution trees. Comput Appl Biosci. 1994 Jul; 10(4):409-12. PMID: 7804873.
      Citations: 12     Fields:    Translation:Animals
    126. Rzhetsky A, Nei M. Unbiased estimates of the number of nucleotide substitutions when substitution rate varies among different sites. J Mol Evol. 1994 Mar; 38(3):295-9. PMID: 8006996.
      Citations: 9     Fields:    Translation:Cells
    127. Rzhetsky A, Nei M. Theoretical foundation of the minimum-evolution method of phylogenetic inference. Mol Biol Evol. 1993 Sep; 10(5):1073-95. PMID: 8412650.
      Citations: 96     Fields:    Translation:HumansAnimals
    128. Rzhetsky A, Nei M. Statistical properties of the ordinary least-squares, generalized least-squares, and minimum-evolution methods of phylogenetic inference. J Mol Evol. 1992 Oct; 35(4):367-75. PMID: 1404422.
      Citations: 63     Fields:    
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