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Yan Yuan Tseng

InstitutionUniversity of Chicago
AddressChicago IL 60637
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Wang B, Lei X, Tian W, Perez-Rathke A, Tseng YY, Liang J. Structure-based pathogenicity relationship identifier for predicting effects of single missense variants and discovery of higher-order cancer susceptibility clusters of mutations. Brief Bioinform. 2023 07 20; 24(4). PMID: 37332013; PMCID: PMC10359089.
      Citations:    Fields:    Translation:Humans
    2. Tseng YY, Sanders MA, Zhang H, Zhou L, Chou CY, Granneman JG. Structural and functional insights into ABHD5, a ligand-regulated lipase co-activator. Sci Rep. 2022 02 16; 12(1):2565. PMID: 35173175; PMCID: PMC8850477.
      Citations: 5     Fields:    Translation:HumansCells
    3. Bhattacharjee MJ, Lin JJ, Chang CY, Chiou YT, Li TN, Tai CW, Shiu TF, Chen CA, Chou CY, Chakraborty P, Tseng YY, Wang LH, Li WH. Identifying Primate ACE2 Variants That Confer Resistance to SARS-CoV-2. Mol Biol Evol. 2021 06 25; 38(7):2715-2731. PMID: 33674876; PMCID: PMC7989403.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    4. Wu WS, Wang LJ, Yen HC, Tseng YY. YQFC: a web tool to compare quantitative biological features between two yeast gene lists. Database (Oxford). 2020 01 01; 2020. PMID: 33186464; PMCID: PMC7805433.
      Citations:    Fields:    Translation:Animals
    5. Lei X, Wang B, Perez-Rathke A, Tian W, Chou CY, Tseng YY, Liang J. Predicting Oncogenic Missense Mutations. IEEE EMBS Int Conf Biomed Health Inform. 2019 May; 2019. PMID: 35261984; PMCID: PMC8901086.
    6. Lin JJ, Bhattacharjee MJ, Yu CP, Tseng YY, Li WH. Many human RNA viruses show extraordinarily stringent selective constraints on protein evolution. Proc Natl Acad Sci U S A. 2019 09 17; 116(38):19009-19018. PMID: 31484772; PMCID: PMC6754614.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    7. Yu K, Lung PY, Zhao T, Zhao P, Tseng YY, Zhang J. Automatic extraction of protein-protein interactions using grammatical relationship graph. BMC Med Inform Decis Mak. 2018 07 23; 18(Suppl 2):42. PMID: 30066644; PMCID: PMC6069288.
      Citations: 10     Fields:    
    8. Sanders MA, Zhang H, Mladenovic L, Tseng YY, Granneman JG. Molecular Basis of ABHD5 Lipolysis Activation. Sci Rep. 2017 02 17; 7:42589. PMID: 28211464; PMCID: PMC5314347.
      Citations: 22     Fields:    Translation:AnimalsCells
    9. Tseng YY, Li WH. PSC: protein surface classification. Nucleic Acids Res. 2012 Jul; 40(Web Server issue):W435-9. PMID: 22669905; PMCID: PMC3394246.
      Citations: 4     Fields:    Translation:HumansCells
    10. Tseng YY, Li WH. Classification of protein functional surfaces using structural characteristics. Proc Natl Acad Sci U S A. 2012 Jan 24; 109(4):1170-5. PMID: 22238424; PMCID: PMC3268291.
      Citations: 11     Fields:    Translation:Cells
    11. Tseng YY, Li WH. Evolutionary approach to predicting the binding site residues of a protein from its primary sequence. Proc Natl Acad Sci U S A. 2011 Mar 29; 108(13):5313-8. PMID: 21402946; PMCID: PMC3069214.
      Citations: 8     Fields:    Translation:Cells
    12. Adamian L, Tseng YY, Muni NJ, Feng F, Qian H, Pepperberg DR, Liang J, Gussin HA. Structural model of rho1 GABAC receptor based on evolutionary analysis: Testing of predicted protein-protein interactions involved in receptor assembly and function. Protein Sci. 2009 Nov; 18(11):2371-83. PMID: 19768800; PMCID: PMC2788291.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    13. Tseng YY, Chen ZJ, Li WH. fPOP: footprinting functional pockets of proteins by comparative spatial patterns. Nucleic Acids Res. 2010 Jan; 38(Database issue):D288-95. PMID: 19880384; PMCID: PMC2808891.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    14. Tseng YY, Li WH. Identification of protein functional surfaces by the concept of a split pocket. Proteins. 2009 Sep; 76(4):959-76. PMID: 19326458.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    15. Tseng YY, Dupree C, Chen ZJ, Li WH. SplitPocket: identification of protein functional surfaces and characterization of their spatial patterns. Nucleic Acids Res. 2009 Jul; 37(Web Server issue):W384-9. PMID: 19406922; PMCID: PMC2703984.
      Citations: 17     Fields:    Translation:HumansCells
    16. Liang J, Tseng YY, Dundas J, Binkowski TA, Joachimiak A, Ouyang Z, Adamian L. Chapter 4. Predicting and characterizing protein functions through matching geometric and evolutionary patterns of binding surfaces. Adv Protein Chem Struct Biol. 2008; 75:107-41. PMID: 20731991; PMCID: PMC2882714.
      Citations: 3     Fields:    Translation:Cells
    17. Tseng YY, Dundas J, Liang J. Predicting protein function and binding profile via matching of local evolutionary and geometric surface patterns. J Mol Biol. 2009 Mar 27; 387(2):451-64. PMID: 19154742; PMCID: PMC2670802.
      Citations: 37     Fields:    Translation:HumansCells
    18. Tseng YY, Liang J. Predicting enzyme functional surfaces and locating key residues automatically from structures. Ann Biomed Eng. 2007 Jun; 35(6):1037-42. PMID: 17294116.
      Citations: 9     Fields:    Translation:Cells
    19. Adamian L, Ouyang Z, Tseng YY, Liang J. Evolutionary patterns of retinal-binding pockets of type I rhodopsins and their functions. Photochem Photobiol. 2006 Nov-Dec; 82(6):1426-35. PMID: 16922602.
      Citations: 6     Fields:    Translation:Cells
    20. Tseng YY, Liang J. Automated method for predicting enzyme functional surfaces and locating key residues with accuracy and specificity. Conf Proc IEEE Eng Med Biol Soc. 2006; 2006:4552-5. PMID: 17947099.
      Citations: 1     Fields:    Translation:Cells
    21. Tseng YY, Liang J. Estimation of amino acid residue substitution rates at local spatial regions and application in protein function inference: a Bayesian Monte Carlo approach. Mol Biol Evol. 2006 Feb; 23(2):421-36. PMID: 16251508.
      Citations: 42     Fields:    Translation:Cells
    22. Tseng YY, Liang J. Are residues in a protein folding nucleus evolutionarily conserved? J Mol Biol. 2004 Jan 23; 335(4):869-80. PMID: 14698285.
      Citations: 14     Fields:    Translation:Cells
    23. Stitziel NO, Binkowski TA, Tseng YY, Kasif S, Liang J. topoSNP: a topographic database of non-synonymous single nucleotide polymorphisms with and without known disease association. Nucleic Acids Res. 2004 Jan 01; 32(Database issue):D520-2. PMID: 14681472; PMCID: PMC308838.
      Citations: 48     Fields:    Translation:HumansCells
    24. Stitziel NO, Tseng YY, Pervouchine D, Goddeau D, Kasif S, Liang J. Structural location of disease-associated single-nucleotide polymorphisms. J Mol Biol. 2003 Apr 11; 327(5):1021-30. PMID: 12662927.
      Citations: 31     Fields:    Translation:Humans
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