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Esra Fatma Tasali

TitleAssociate Professor
InstitutionUniversity of Chicago
DepartmentMedicine-Pulmonary/Critical Care
AddressChicago IL 60637
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    Collapse Overview 
    Collapse overview
    Associate Professor of Medicine
    Section of Pulmonary and Critical Care Medicine
    Department of Medicine
    The University of Chicago

    My research program focuses on the role of insufficient sleep in the development of metabolic diseases including type 2 diabetes and obesity. I have extensive experience investigating the relationships between sleep loss and metabolic disruptions utilizing experimental laboratory models in healthy humans, clinical studies in patients with obstructive sleep apnea, and field studies on energy metabolism in individuals at risk for diabetes and obesity.

    My NIH COMMONS name is etasali.


    Collapse Biography 
    Collapse awards and honors
    2001Alan Rechtshaffen Award, The University of Chicago
    2005Young Investigator Award of the American Academy of Sleep Medicine, American Academy of Sleep Medicine
    2006Best Clinical Research, The University of Chicago
    2006American Academy of Sleep Medicine/Pfizer Scholar in Sleep Medicine , American Academy of Sleep Medicine
    2008Young Investigator Award of the Sleep Research Society, Sleep Research Society

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Pamidi S, Chapotot F, Wroblewski K, Whitmore H, Polonsky T, Tasali E. Optimal Continuous Positive Airway Pressure Treatment of Obstructive Sleep Apnea Reduces Daytime Resting Heart Rate in Prediabetes: A Randomized Controlled Study. J Am Heart Assoc. 2020 Oct 20; 9(19):e016871. PMID: 32998624.
      View in: PubMed
    2. St-Onge MP, Tasali E. Weight Loss Is Integral to OSA Management: 10-year Follow-up in Sleep AHEAD. Am J Respir Crit Care Med. 2020 Aug 14. PMID: 32795248.
      View in: PubMed
    3. Morselli LL, Gamazon ER, Tasali E, Cox NJ, Van Cauter E, Davis LK. Shared Genetic Control of Brain Activity During Sleep and Insulin Secretion: A Laboratory-Based Family Study. Diabetes. 2018 01; 67(1):155-164. PMID: 29084784.
      View in: PubMed
    4. Bhutani S, Kahn E, Tasali E, Schoeller DA. Composition of two-week change in body weight under unrestricted free-living conditions. Physiol Rep. 2017 Jul; 5(13). PMID: 28676555.
      View in: PubMed
    5. Guyon A, Morselli LL, Balbo ML, Tasali E, Leproult R, L'Hermite-Balériaux M, Van Cauter E, Spiegel K. Effects of Insufficient Sleep on Pituitary-Adrenocortical Response to CRH Stimulation in Healthy Men. Sleep. 2017 06 01; 40(6). PMID: 28444400.
      View in: PubMed
    6. Pamidi S, Tasali E. Continuous Positive Airway Pressure for Improving Glycemic Control in Type 2 Diabetes: Where Do We Stand? Am J Respir Crit Care Med. 2016 08 15; 194(4):397-400. PMID: 27525459.
      View in: PubMed
    7. Jacome-Sosa M, Parks EJ, Bruno RS, Tasali E, Lewis GF, Schneeman BO, Rains TM. Postprandial Metabolism of Macronutrients and Cardiometabolic Risk: Recent Developments, Emerging Concepts, and Future Directions. Adv Nutr. 2016 Mar; 7(2):364-74. PMID: 26980820.
      View in: PubMed
    8. Hanlon EC, Tasali E, Leproult R, Stuhr KL, Doncheck E, de Wit H, Hillard CJ, Van Cauter E. Sleep Restriction Enhances the Daily Rhythm of Circulating Levels of Endocannabinoid 2-Arachidonoylglycerol. Sleep. 2016 Mar 01; 39(3):653-64. PMID: 26612385.
      View in: PubMed
    9. Broussard JL, Wroblewski K, Kilkus JM, Tasali E. Two Nights of Recovery Sleep Reverses the Effects of Short-term Sleep Restriction on Diabetes Risk. Diabetes Care. 2016 Mar; 39(3):e40-1. PMID: 26786578.
      View in: PubMed
    10. Broussard JL, Kilkus JM, Delebecque F, Abraham V, Day A, Whitmore HR, Tasali E. Elevated ghrelin predicts food intake during experimental sleep restriction. Obesity (Silver Spring). 2016 Jan; 24(1):132-8. PMID: 26467988.
      View in: PubMed
    11. Joint Consensus Statement of the American Academy of Sleep Medicine and Sleep Research Society on the Recommended Amount of Sleep for a Healthy Adult: Methodology and Discussion. J Clin Sleep Med. 2015 Aug 15; 11(8):931-52. PMID: 26235159.
      View in: PubMed
    12. Joint Consensus Statement of the American Academy of Sleep Medicine and Sleep Research Society on the Recommended Amount of Sleep for a Healthy Adult: Methodology and Discussion. Sleep. 2015 Aug 01; 38(8):1161-83. PMID: 26194576.
      View in: PubMed
    13. Pamidi S, Wroblewski K, Stepien M, Sharif-Sidi K, Kilkus J, Whitmore H, Tasali E. Eight Hours of Nightly Continuous Positive Airway Pressure Treatment of Obstructive Sleep Apnea Improves Glucose Metabolism in Patients with Prediabetes. A Randomized Controlled Trial. Am J Respir Crit Care Med. 2015 Jul 01; 192(1):96-105. PMID: 25897569.
      View in: PubMed
    14. Recommended Amount of Sleep for a Healthy Adult: A Joint Consensus Statement of the American Academy of Sleep Medicine and Sleep Research Society. J Clin Sleep Med. 2015 Jun 15; 11(6):591-2. PMID: 25979105.
      View in: PubMed
    15. Watson NF, Badr MS, Belenky G, Bliwise DL, Buxton OM, Buysse D, Dinges DF, Gangwisch J, Grandner MA, Kushida C, Malhotra RK, Martin JL, Patel SR, Quan SF, Tasali E. Recommended Amount of Sleep for a Healthy Adult: A Joint Consensus Statement of the American Academy of Sleep Medicine and Sleep Research Society. Sleep. 2015 Jun 01; 38(6):843-4. PMID: 26039963.
      View in: PubMed
    16. Broussard JL, Chapotot F, Abraham V, Day A, Delebecque F, Whitmore HR, Tasali E. Sleep restriction increases free fatty acids in healthy men. Diabetologia. 2015 Apr; 58(4):791-8. PMID: 25702040.
      View in: PubMed
    17. Hanlon EC, Tasali E, Leproult R, Stuhr KL, Doncheck E, de Wit H, Hillard CJ, Van Cauter E. Circadian rhythm of circulating levels of the endocannabinoid 2-arachidonoylglycerol. J Clin Endocrinol Metab. 2015 Jan; 100(1):220-6. PMID: 25368979.
      View in: PubMed
    18. Ayas NT, Hirsch AA, Laher I, Bradley TD, Malhotra A, Polotsky VY, Tasali E. New frontiers in obstructive sleep apnoea. Clin Sci (Lond). 2014 Aug; 127(4):209-16. PMID: 24780001.
      View in: PubMed
    19. Tasali E, Chapotot F, Wroblewski K, Schoeller D. The effects of extended bedtimes on sleep duration and food desire in overweight young adults: a home-based intervention. Appetite. 2014 Sep; 80:220-4. PMID: 24858836.
      View in: PubMed
    20. Guyon A, Balbo M, Morselli LL, Tasali E, Leproult R, L'Hermite-Balériaux M, Van Cauter E, Spiegel K. Adverse effects of two nights of sleep restriction on the hypothalamic-pituitary-adrenal axis in healthy men. J Clin Endocrinol Metab. 2014 Aug; 99(8):2861-8. PMID: 24823456.
      View in: PubMed
    21. Broussard JL, Ehrmann DA, Van Cauter E, Tasali E, Brady MJ. Impaired insulin signaling in human adipocytes after experimental sleep restriction: a randomized, crossover study. Ann Intern Med. 2012 Oct 16; 157(8):549-57. PMID: 23070488.
      View in: PubMed
    22. Pamidi S, Wroblewski K, Broussard J, Day A, Hanlon EC, Abraham V, Tasali E. Obstructive sleep apnea in young lean men: impact on insulin sensitivity and secretion. Diabetes Care. 2012 Nov; 35(11):2384-9. PMID: 22912423.
      View in: PubMed
    23. Pamidi S, Tasali E. Obstructive sleep apnea and type 2 diabetes: is there a link? Front Neurol. 2012; 3:126. PMID: 23015803.
      View in: PubMed
    24. Tasali E, Chapotot F, Leproult R, Whitmore H, Ehrmann DA. Treatment of obstructive sleep apnea improves cardiometabolic function in young obese women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2011 Feb; 96(2):365-74. PMID: 21123449.
      View in: PubMed
    25. Spiegel K, Tasali E, Leproult R, Scherberg N, Van Cauter E. Twenty-four-hour profiles of acylated and total ghrelin: relationship with glucose levels and impact of time of day and sleep. J Clin Endocrinol Metab. 2011 Feb; 96(2):486-93. PMID: 21106712.
      View in: PubMed
    26. Pamidi S, Aronsohn RS, Tasali E. Obstructive sleep apnea: role in the risk and severity of diabetes. Best Pract Res Clin Endocrinol Metab. 2010 Oct; 24(5):703-15. PMID: 21112020.
      View in: PubMed
    27. Aronsohn RS, Whitmore H, Van Cauter E, Tasali E. Impact of untreated obstructive sleep apnea on glucose control in type 2 diabetes. Am J Respir Crit Care Med. 2010 Mar 01; 181(5):507-13. PMID: 20019340.
      View in: PubMed
    28. Spiegel K, Tasali E, Leproult R, Van Cauter E. Effects of poor and short sleep on glucose metabolism and obesity risk. Nat Rev Endocrinol. 2009 May; 5(5):253-61. PMID: 19444258.
      View in: PubMed
    29. Tasali E, Leproult R, Spiegel K. Reduced sleep duration or quality: relationships with insulin resistance and type 2 diabetes. Prog Cardiovasc Dis. 2009 Mar-Apr; 51(5):381-91. PMID: 19249444.
      View in: PubMed
    30. Van Cauter E, Spiegel K, Tasali E, Leproult R. Metabolic consequences of sleep and sleep loss. Sleep Med. 2008 Sep; 9 Suppl 1:S23-8. PMID: 18929315.
      View in: PubMed
    31. Tasali E, Van Cauter E, Hoffman L, Ehrmann DA. Impact of obstructive sleep apnea on insulin resistance and glucose tolerance in women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2008 Oct; 93(10):3878-84. PMID: 18647805.
      View in: PubMed
    32. Tasali E, Van Cauter E, Ehrmann DA. Polycystic Ovary Syndrome and Obstructive Sleep Apnea. Sleep Med Clin. 2008 Mar; 3(1):37-46. PMID: 19255602.
      View in: PubMed
    33. Tasali E, Ip MS. Obstructive sleep apnea and metabolic syndrome: alterations in glucose metabolism and inflammation. Proc Am Thorac Soc. 2008 Feb 15; 5(2):207-17. PMID: 18250214.
      View in: PubMed
    34. Tasali E, Mokhlesi B, Van Cauter E. Obstructive sleep apnea and type 2 diabetes: interacting epidemics. Chest. 2008 Feb; 133(2):496-506. PMID: 18252916.
      View in: PubMed
    35. Tasali E, Leproult R, Ehrmann DA, Van Cauter E. Slow-wave sleep and the risk of type 2 diabetes in humans. Proc Natl Acad Sci U S A. 2008 Jan 22; 105(3):1044-9. PMID: 18172212.
      View in: PubMed
    36. Van Cauter E, Holmback U, Knutson K, Leproult R, Miller A, Nedeltcheva A, Pannain S, Penev P, Tasali E, Spiegel K. Impact of sleep and sleep loss on neuroendocrine and metabolic function. Horm Res. 2007; 67 Suppl 1:2-9. PMID: 17308390.
      View in: PubMed
    37. Latta F, Leproult R, Tasali E, Hofmann E, Van Cauter E. Sex differences in delta and alpha EEG activities in healthy older adults. Sleep. 2005 Dec; 28(12):1525-34. PMID: 16408411.
      View in: PubMed
    38. Latta F, Leproult R, Tasali E, Hofmann E, L'Hermite-Balériaux M, Copinschi G, Van Cauter E. Sex differences in nocturnal growth hormone and prolactin secretion in healthy older adults: relationships with sleep EEG variables. Sleep. 2005 Dec; 28(12):1519-24. PMID: 16408410.
      View in: PubMed
    39. Spiegel K, Knutson K, Leproult R, Tasali E, Van Cauter E. Sleep loss: a novel risk factor for insulin resistance and Type 2 diabetes. J Appl Physiol (1985). 2005 Nov; 99(5):2008-19. PMID: 16227462.
      View in: PubMed
    40. Tasali E, Van Cauter E, Ehrmann DA. Relationships between sleep disordered breathing and glucose metabolism in polycystic ovary syndrome. J Clin Endocrinol Metab. 2006 Jan; 91(1):36-42. PMID: 16219719.
      View in: PubMed
    41. Spiegel K, Tasali E, Penev P, Van Cauter E. Brief communication: Sleep curtailment in healthy young men is associated with decreased leptin levels, elevated ghrelin levels, and increased hunger and appetite. Ann Intern Med. 2004 Dec 07; 141(11):846-50. PMID: 15583226.
      View in: PubMed
    42. Tasali E, Van Cauter E. Sleep-disordered breathing and the current epidemic of obesity: consequence or contributing factor? Am J Respir Crit Care Med. 2002 Mar 01; 165(5):562-3. PMID: 11874803.
      View in: PubMed
    43. Erkan F, Gül A, Tasali E. Pulmonary manifestations of Behçet's disease. Thorax. 2001 Jul; 56(7):572-8. PMID: 11413359.
      View in: PubMed
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